{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T12:34:23Z","timestamp":1793450063454,"version":"4.5.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFC2309801"],"award-info":[{"award-number":["2024YFC2309801"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFC2309802"],"award-info":[{"award-number":["2024YFC2309802"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["L242117"],"award-info":[{"award-number":["L242117"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013290","name":"National Key Research and Development Program of China Stem Cell and Translational Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013290","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005088","name":"Beijing Municipal Health Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005088","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virologica Sinica"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.virs.2026.09.004","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T07:13:14Z","timestamp":1789024394000},"page":"1045-1053","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epidemiological characteristics and in-hospital burden of infectious mononucleosis among hospitalized children in China, 2021\u20132023"],"prefix":"10.1016","volume":"41","author":[{"given":"Yuxin","family":"Shao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyi","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueping","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoshuang","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7634-9338","authenticated-orcid":false,"given":"Zhengde","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0243-8538","authenticated-orcid":false,"given":"Ran","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virs.2026.09.004_bib1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jped.2015.06.007","article-title":"Atypical manifestations of Epstein-Barr virus in children: a diagnostic challenge","volume":"92","author":"Bolis","year":"2016","journal-title":"J. Pediatr."},{"key":"10.1016\/j.virs.2026.09.004_bib2","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2023.1064330","article-title":"Seroprevalence of Epstein-Barr virus infection in children during the COVID-19 pandemic in Zhejiang, China","volume":"11","author":"Cai","year":"2023","journal-title":"Front. Pediatr."},{"key":"10.1016\/j.virs.2026.09.004_bib3","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1386-6532(01)00149-4","article-title":"Epstein-Barr virus (EBV) infection in infancy","volume":"21","author":"Chan","year":"2001","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.virs.2026.09.004_bib4","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-020-05623-1","article-title":"Clinical characteristics of Epstein-Barr virus infection in the pediatric nervous system","volume":"20","author":"Cheng","year":"2020","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.virs.2026.09.004_bib5","doi-asserted-by":"crossref","DOI":"10.1186\/1756-0500-5-361","article-title":"Clinical and laboratory characteristics of infectious mononucleosis by Epstein-Barr virus in Mexican children","volume":"5","author":"Gonzalez Saldana","year":"2012","journal-title":"BMC Res. Notes"},{"key":"10.1016\/j.virs.2026.09.004_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1000496","article-title":"The dynamics of EBV shedding implicate a central role for epithelial cells in amplifying viral output","volume":"5","author":"Hadinoto","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virs.2026.09.004_bib7","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/ped4.12294","article-title":"Clinical characteristics and effectiveness of antiviral agents in hospitalized children with infectious mononucleosis in China: a multicenter retrospective study","volume":"5","author":"Hu","year":"2021","journal-title":"Pediatr Investig"},{"key":"10.1016\/j.virs.2026.09.004_bib8","article-title":"Impact of the COVID-19 nonpharmaceutical interventions on influenza and other respiratory viral infections in New Zealand","volume":"12","author":"Huang","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.virs.2026.09.004_bib9","article-title":"Temporal shifts in 24 notifiable infectious diseases in China before and during the COVID-19 pandemic","volume":"15","author":"Li","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.virs.2026.09.004_bib10","doi-asserted-by":"crossref","first-page":"e1054","DOI":"10.1093\/cid\/ciab942","article-title":"Broad impacts of coronavirus disease 2019 (COVID-19) pandemic on acute respiratory infections in China: an observational study","volume":"75","author":"Li","year":"2022","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.virs.2026.09.004_bib11","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.jinf.2023.01.021","article-title":"The influences of the COVID-19 pandemic on Epstein-Barr virus infection in children, Henan, China","volume":"86","author":"Liang","year":"2023","journal-title":"J. Infect."},{"key":"10.1016\/j.virs.2026.09.004_bib12","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.virs.2022.07.007","article-title":"Epidemiological characteristics and disease burden of infectious mononucleosis in hospitalized children in China: a nationwide retrospective study","volume":"37","author":"Liu","year":"2022","journal-title":"Virol. Sin."},{"key":"10.1016\/j.virs.2026.09.004_bib13","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1056\/NEJMcp1001116","article-title":"Infectious mononucleosis","volume":"362","author":"Luzuriaga","year":"2010","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.virs.2026.09.004_bib14","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S1473-3099(03)00543-7","article-title":"Epstein-Barr virus-recent advances","volume":"3","author":"Macsween","year":"2003","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.virs.2026.09.004_bib15","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens14040374","article-title":"Clinical features and laboratory findings of hospitalized children with infectious mononucleosis caused by Epstein-Barr virus from Croatia","volume":"14","author":"Prtoric","year":"2025","journal-title":"Pathogens"},{"key":"10.1016\/j.virs.2026.09.004_bib16","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2018.00211","article-title":"Epstein-Barr virus epidemiology, serology, and genetic variability of LMP-1 oncogene among healthy population: an update","volume":"8","author":"Smatti","year":"2018","journal-title":"Front. Oncol."},{"key":"10.1016\/j.virs.2026.09.004_bib17","first-page":"905","article-title":"[Experts consensus on diagnosis and treatment of Epstein-Barr virus infection-related diseases in children]","volume":"59","year":"2021","journal-title":"Zhonghua Er Ke Za Zhi"},{"key":"10.1016\/j.virs.2026.09.004_bib18","first-page":"563","article-title":"[Principle suggestions for diagnosis and treatment of main nontumorous Epstein-Barr virus-associated diseases in children]","volume":"54","year":"2016","journal-title":"Zhonghua Er Ke Za Zhi"},{"key":"10.1016\/j.virs.2026.09.004_bib19","doi-asserted-by":"crossref","first-page":"908","DOI":"10.3109\/23744235.2015.1082036","article-title":"Clinical characteristics and laboratory findings in Danish children hospitalized with primary Epstein-Barr virus infection","volume":"47","author":"Topp","year":"2015","journal-title":"Infect. Dis. (Lond.)"},{"key":"10.1016\/j.virs.2026.09.004_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.micinf.2021.104911","article-title":"Impact of non-pharmaceutical interventions during the COVID-19 pandemic on common childhood respiratory viruses - an epidemiological study based on hospital data","volume":"24","author":"Ye","year":"2022","journal-title":"Microb. Infect."},{"key":"10.1016\/j.virs.2026.09.004_bib21","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1002\/jmv.27570","article-title":"Epidemiological changes of common respiratory viruses in children during the COVID-19 pandemic","volume":"94","author":"Ye","year":"2022","journal-title":"J. Med. Virol."}],"container-title":["Virologica Sinica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1995820X26001653?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1995820X26001653?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T12:17:49Z","timestamp":1793449069000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1995820X26001653"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S1995820X26001653"],"URL":"https:\/\/doi.org\/10.1016\/j.virs.2026.09.004","relation":{},"ISSN":["1995-820X"],"issn-type":[{"value":"1995-820X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epidemiological characteristics and in-hospital burden of infectious mononucleosis among hospitalized children in China, 2021\u20132023","name":"articletitle","label":"Article Title"},{"value":"Virologica Sinica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virs.2026.09.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.","name":"copyright","label":"Copyright"}]}}