{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T12:30:26Z","timestamp":1791117026099,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T00:00:00Z","timestamp":1120176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T00:00:00Z","timestamp":1120176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP\u201364376"],"award-info":[{"award-number":["MOP\u201364376"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virus Research"],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1016\/j.virusres.2005.03.010","type":"journal-article","created":{"date-parts":[[2005,4,30]],"date-time":"2005-04-30T07:22:07Z","timestamp":1114845727000},"page":"55-60","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Comparative pathogenesis of the SAD-L16 strain of rabies virus and a mutant modifying the dynein light chain binding site of the rabies virus phosphoprotein in young mice"],"prefix":"10.1016","volume":"111","author":[{"given":"Pamini","family":"Rasalingam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Rossiter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teshome","family":"Mebatsion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan C.","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virusres.2005.03.010_bib1","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1046\/j.1460-9568.2003.02497.x","article-title":"Connecting the dots: trafficking of neurotrophins, lectins and diverse pathogens by binding to the neurotrophin receptor p75NTR","volume":"17","author":"Butowt","year":"2003","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.virusres.2005.03.010_bib2","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1097\/00005072-198611000-00002","article-title":"Axonal transport of rabies virus in the central nervous system of the rat","volume":"45","author":"Gillet","year":"1986","journal-title":"J. Neuropathol. Exp. Neurol."},{"issue":"Suppl. 1","key":"10.1016\/j.virusres.2005.03.010_bib3","first-page":"A102","article-title":"Neuronal apoptosis in experimental rabies: role of the route of viral entry","volume":"60","author":"Jackson","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.virusres.2005.03.010_bib4","series-title":"Rabies","first-page":"245","article-title":"Pathogenesis","author":"Jackson","year":"2002"},{"key":"10.1016\/j.virusres.2005.03.010_bib5","series-title":"Rabies","first-page":"219","article-title":"Human disease","author":"Jackson","year":"2002"},{"key":"10.1016\/j.virusres.2005.03.010_bib6","first-page":"85","article-title":"Animal models of rabies virus neurovirulence","volume":"vol. 187","author":"Jackson","year":"1994"},{"key":"10.1016\/j.virusres.2005.03.010_bib7","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s004010050781","article-title":"Apoptotic cell death in experimental rabies in suckling mice","volume":"95","author":"Jackson","year":"1998","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.virusres.2005.03.010_bib8","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/BF00688204","article-title":"Pathogenesis of experimental rabies in mice: an immunohistochemical study","volume":"78","author":"Jackson","year":"1989","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.virusres.2005.03.010_bib9","doi-asserted-by":"crossref","first-page":"5603","DOI":"10.1128\/jvi.71.7.5603-5607.1997","article-title":"Apoptosis plays an important role in experimental rabies virus infection","volume":"71","author":"Jackson","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2005.03.010_bib10","series-title":"Rabies","author":"Jackson","year":"2002"},{"key":"10.1016\/j.virusres.2005.03.010_bib11","first-page":"945","article-title":"Extraneural organ involvement in human rabies","volume":"79","author":"Jackson","year":"1999","journal-title":"Lab. Invest."},{"key":"10.1016\/j.virusres.2005.03.010_bib12","doi-asserted-by":"crossref","first-page":"10217","DOI":"10.1128\/JVI.74.21.10217-10222.2000","article-title":"Cytoplasmic dynein LC8 interacts with lyssavirus phosphoprotein","volume":"74","author":"Jacob","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2005.03.010_bib13","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1080\/13550280590900427","article-title":"Rabies virus receptors","volume":"11","author":"Lafon","year":"2005","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.virusres.2005.03.010_bib14","doi-asserted-by":"crossref","first-page":"14059","DOI":"10.1074\/jbc.M010320200","article-title":"The 8-kDa dynein light chain binds to its targets via a conserved (K\/R)XTQT motif","volume":"276","author":"Lo","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2005.03.010_bib15","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1093\/hmg\/10.19.2109","article-title":"Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery","volume":"10","author":"Mazarakis","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.virusres.2005.03.010_bib16","doi-asserted-by":"crossref","first-page":"11496","DOI":"10.1128\/JVI.75.23.11496-11502.2001","article-title":"Extensive attenuation of rabies virus by simultaneously modifying the dynein light chain binding site in the P protein and replacing Arg333 in the G protein","volume":"75","author":"Mebatsion","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2005.03.010_bib17","doi-asserted-by":"crossref","first-page":"7897","DOI":"10.1074\/jbc.M111937200","article-title":"Interaction of the poliovirus receptor CD155 with the dynein light chain Tctex-1 and its implication for poliovirus pathogenesis","volume":"277","author":"Mueller","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2005.03.010_bib18","series-title":"Rabies","first-page":"163","article-title":"Animal rabies","author":"Niezgoda","year":"2002"},{"key":"10.1016\/j.virusres.2005.03.010_bib19","first-page":"100","article-title":"Recombinant rabies virus vaccine strain SAD-L16 inoculated intracerebrally in young mice produces a severe encephalitis with extensive neuronal apoptosis","volume":"69","author":"Rasalingam","year":"2005","journal-title":"Can. J. Vet. Res."},{"key":"10.1016\/j.virusres.2005.03.010_bib20","unstructured":"Rasalingam, P., Rossiter, J.P., Mebatsion, T., Jackson, A.C., 2003. Pathogenesis of SAD-L16 and mutants modifying the dynein light chain (LC8) binding site and replacing arg333 in the rabies virus glycoprotein in suckling mice. Presented at the XIVth International Meeting on Research Advances and Rabies Control in the Americas in Philadelphia, PA 21 October, 2003."},{"key":"10.1016\/j.virusres.2005.03.010_bib21","doi-asserted-by":"crossref","first-page":"10212","DOI":"10.1128\/JVI.74.21.10212-10216.2000","article-title":"Interaction of the rabies virus P protein with the LC8 dynein light chain","volume":"74","author":"Raux","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2005.03.010_bib22","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1080\/135502801753248097","article-title":"Experimental rabies virus infection in Artibeus jamaicensis bats with CVS-24 variants","volume":"7","author":"Reid","year":"2001","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.virusres.2005.03.010_bib23","doi-asserted-by":"crossref","first-page":"4195","DOI":"10.1002\/j.1460-2075.1994.tb06739.x","article-title":"Infectious rabies viruses from cloned cDNA","volume":"13","author":"Schnell","year":"1994","journal-title":"EMBO J."},{"key":"10.1016\/j.virusres.2005.03.010_bib24","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1080\/13550280590900436","article-title":"The application of reverse genetics technology in the study of rabies virus (RV) pathogenesis and for the development of novel RV vaccines","volume":"11","author":"Schnell","year":"2005","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.virusres.2005.03.010_bib25","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1099\/0022-1317-65-4-781","article-title":"Mechanism of rabies virus entry into CER cells","volume":"65","author":"Superti","year":"1984","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virusres.2005.03.010_bib26","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1097\/00005072-197905000-00008","article-title":"Evidence for an intraaxonal transport of fixed and street rabies virus","volume":"38","author":"Tsiang","year":"1979","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.virusres.2005.03.010_bib27","doi-asserted-by":"crossref","first-page":"7250","DOI":"10.1093\/emboj\/17.24.7250","article-title":"Low-affinity nerve-growth factor receptor (P75NTR) can serve as a receptor for rabies virus","volume":"17","author":"Tuffereau","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/j.virusres.2005.03.010_bib28","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/neu.10314","article-title":"Dynein: an ancient motor protein involved in multiple modes of transport","volume":"58","author":"Vallee","year":"2004","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.virusres.2005.03.010_bib29","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/neu.10315","article-title":"Axonal transport and neuronal transcytosis of trophic factors, tracers, and pathogens","volume":"58","author":"Von Bartheld","year":"2004","journal-title":"J. Neurobiol."}],"container-title":["Virus Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170205000742?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170205000742?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T14:00:12Z","timestamp":1759154412000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168170205000742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["S0168170205000742"],"URL":"https:\/\/doi.org\/10.1016\/j.virusres.2005.03.010","relation":{},"ISSN":["0168-1702"],"issn-type":[{"value":"0168-1702","type":"print"}],"subject":[],"published":{"date-parts":[[2005,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparative pathogenesis of the SAD-L16 strain of rabies virus and a mutant modifying the dynein light chain binding site of the rabies virus phosphoprotein in young mice","name":"articletitle","label":"Article Title"},{"value":"Virus Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virusres.2005.03.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}