{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T01:53:37Z","timestamp":1791338017514,"version":"4.3.1"},"reference-count":70,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Virus Research"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1016\/j.virusres.2008.01.007","type":"journal-article","created":{"date-parts":[[2008,3,5]],"date-time":"2008-03-05T18:20:24Z","timestamp":1204741224000},"page":"64-73","source":"Crossref","is-referenced-by-count":84,"title":["Implications of recombination for HIV diversity"],"prefix":"10.1016","volume":"134","author":[{"given":"Bertha Cecilia","family":"Ramirez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Simon-Loriere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roman","family":"Galetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Negroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virusres.2008.01.007_bib1","doi-asserted-by":"crossref","first-page":"8543","DOI":"10.1128\/JVI.00463-07","article-title":"Recombination confounds the early evolutionary history of human immunodeficiency virus type 1: subtype G is a circulating recombinant form","volume":"81","author":"Abecasis","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib2","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1128\/JVI.72.2.1195-1202.1998","article-title":"Retroviral recombination rates do not increase linearly with marker distance and are limited by the size of the recombining subpopulation","volume":"72","author":"Anderson","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib3","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1086\/512682","article-title":"HIV-1 subtype D infection is associated with faster disease progression than subtype A in spite of similar plasma HIV-1 loads","volume":"195","author":"Baeten","year":"2007","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virusres.2008.01.007_bib4","doi-asserted-by":"crossref","first-page":"5203","DOI":"10.1093\/nar\/gkl669","article-title":"Sequence determinants of breakpoint location during HIV-1 intersubtype recombination","volume":"34","author":"Baird","year":"2006","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.virusres.2008.01.007_bib5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.virusres.2007.12.017","article-title":"Strand transfer events during HIV-1 reverse transcription","volume":"134","author":"Basu","year":"2008","journal-title":"Virus Res."},{"key":"10.1016\/j.virusres.2008.01.007_bib6","doi-asserted-by":"crossref","first-page":"5198","DOI":"10.1128\/JVI.72.6.5198-5206.1998","article-title":"Relative rates of retroviral reverse transcriptase template switching during RNA- and DNA-dependent DNA synthesis","volume":"72","author":"Bowman","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib7","doi-asserted-by":"crossref","first-page":"10209","DOI":"10.1128\/JVI.00872-07","article-title":"Human immunodeficiency virus type 1 subtype distribution in the worldwide epidemic: pathogenetic and therapeutic implications","volume":"81","author":"Buonaguro","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib8","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1172\/JCI200522873","article-title":"HIV-1 clade promoters strongly influence spatial and temporal dynamics of viral replication in vivo","volume":"115","author":"Centlivre","year":"2005","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.virusres.2008.01.007_bib9","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.virol.2007.01.034","article-title":"Molecular determinants of HIV-1 intersubtype recombination potential","volume":"363","author":"Chin","year":"2007","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2008.01.007_bib10","doi-asserted-by":"crossref","first-page":"9002","DOI":"10.1073\/pnas.0502522102","article-title":"Identification of a major restriction in HIV-1 intersubtype recombination","volume":"102","author":"Chin","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.virusres.2008.01.007_bib11","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1128\/JVI.78.4.1962-1970.2004","article-title":"Comparative study of adaptive molecular evolution in different human immunodeficiency virus groups and subtypes","volume":"78","author":"Choisy","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib12","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1023\/B:VIRU.0000025773.12621.a8","article-title":"Evidence for selection of more adapted human immunodeficiency virus type 1 recombinant strains in a dually infected transfusion recipient","volume":"28","author":"Costa","year":"2004","journal-title":"Virus Genes"},{"key":"10.1016\/j.virusres.2008.01.007_bib13","doi-asserted-by":"crossref","first-page":"47446","DOI":"10.1074\/jbc.M408927200","article-title":"Mechanistic analysis of pause site-dependent and -independent recombinogenic strand transfer from structurally diverse regions of the HIV genome","volume":"279","author":"Derebail","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2008.01.007_bib14","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0021-9258(17)42329-5","article-title":"The mechanism of human immunodeficiency virus reverse transcriptase-catalyzed strand transfer from internal regions of heteropolymeric RNA templates","volume":"269","author":"DeStefano","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2008.01.007_bib15","doi-asserted-by":"crossref","first-page":"6370","DOI":"10.1128\/JVI.66.11.6370-6378.1992","article-title":"Requirements for strand transfer between internal regions of heteropolymer templates by human immunodeficiency virus reverse transcriptase","volume":"66","author":"DeStefano","year":"1992","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib16","doi-asserted-by":"crossref","first-page":"3273","DOI":"10.1128\/JVI.69.6.3273-3281.1995","article-title":"Dual human immunodeficiency virus type 1 infection and recombination in a dually exposed transfusion recipient. The Transfusion Safety Study Group","volume":"69","author":"Diaz","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib17","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1099\/0022-1317-83-10-2533","article-title":"Requirements for RNA heterodimerization of the human immunodeficiency virus type 1 (HIV-1) and HIV-2 genomes","volume":"83","author":"Dirac","year":"2002","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib18","doi-asserted-by":"crossref","first-page":"F9","DOI":"10.1083\/jcb.151.2.F9","article-title":"HIV-1 membrane fusion: targets of opportunity","volume":"151","author":"Doms","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.virusres.2008.01.007_bib19","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1534\/genetics.105.052019","article-title":"Evolution of the human immunodeficiency virus envelope gene is dominated by purifying selection","volume":"174","author":"Edwards","year":"2006","journal-title":"Genetics"},{"key":"10.1016\/j.virusres.2008.01.007_bib20","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.meegid.2007.07.012","article-title":"The distribution of HIV-1 recombination breakpoints","volume":"6","author":"Fan","year":"2007","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.virusres.2008.01.007_bib21","doi-asserted-by":"crossref","first-page":"29605","DOI":"10.1074\/jbc.271.47.29605","article-title":"Strand displacement synthesis in the central polypurine tract region of HIV-1 promotes DNA to DNA strand transfer recombination","volume":"271","author":"Fuentes","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2008.01.007_bib22","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1074\/jbc.M505457200","article-title":"Dissection of a circumscribed recombination hot spot in HIV-1 after a single infectious cycle","volume":"281","author":"Galetto","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2008.01.007_bib23","doi-asserted-by":"crossref","first-page":"36625","DOI":"10.1074\/jbc.M405476200","article-title":"The structure of HIV-1 genomic RNA in the gp120 gene determines a recombination hot spot in vivo","volume":"279","author":"Galetto","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2008.01.007_bib24","first-page":"92","article-title":"Mechanistic features of recombination in HIV","volume":"7","author":"Galetto","year":"2005","journal-title":"AIDS Rev."},{"key":"10.1016\/j.virusres.2008.01.007_bib25","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1038\/17130","article-title":"Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes","volume":"397","author":"Gao","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2008.01.007_bib26","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/358495a0","article-title":"Human infection by genetically diverse SIVSM-related HIV-2 in west Africa","volume":"358","author":"Gao","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2008.01.007_bib27","doi-asserted-by":"crossref","first-page":"6222","DOI":"10.1074\/jbc.M610056200","article-title":"Insights into the multiple roles of pausing in HIV-1 reverse transcriptase-promoted strand transfers","volume":"282","author":"Gao","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2008.01.007_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.qco.0000200293.45532.68","article-title":"HIV-1 subtypes: epidemiology and significance for HIV management","volume":"19","author":"Geretti","year":"2006","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.virusres.2008.01.007_bib29","doi-asserted-by":"crossref","first-page":"4886","DOI":"10.1128\/JVI.01954-06","article-title":"Clade-specific differences between human immunodeficiency virus type 1 clades B and C: diversity and correlations in C3-V4 regions of gp120","volume":"81","author":"Gnanakaran","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib30","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1128\/JVI.38.1.136-150.1981","article-title":"Generation of novel, biologically active Harvey sarcoma viruses via apparent illegitimate recombination","volume":"38","author":"Goldfarb","year":"1981","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib31","doi-asserted-by":"crossref","first-page":"5413","DOI":"10.1128\/JVI.02554-06","article-title":"Independent evolution of human immunodeficiency virus type 1 env V1\/V2 and V4\/V5 hypervariable regions during chronic infection","volume":"81","author":"Harrington","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib32","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/373123a0","article-title":"Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection","volume":"373","author":"Ho","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2008.01.007_bib33","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1073\/pnas.87.4.1556","article-title":"Genetic consequences of packaging two RNA genomes in one retroviral particle: pseudodiploidy and high rate of genetic recombination","volume":"87","author":"Hu","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.virusres.2008.01.007_bib34","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1128\/JVI.74.3.1234-1240.2000","article-title":"High rate of recombination throughout the human immunodeficiency virus type 1 genome","volume":"74","author":"Jetzt","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib35","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/418144a","article-title":"Multiply infected spleen cells in HIV patients","volume":"418","author":"Jung","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2008.01.007_bib36","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0092-8674(82)90011-3","article-title":"Retroviral DNA H structures: displacement-assimilation model of recombination","volume":"30","author":"Junghans","year":"1982","journal-title":"Cell"},{"key":"10.1016\/j.virusres.2008.01.007_bib37","doi-asserted-by":"crossref","first-page":"e112","DOI":"10.1371\/journal.pmed.0020112","article-title":"Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: results of a global collaboration","volume":"2","author":"Kantor","year":"2005","journal-title":"PLoS Med."},{"key":"10.1016\/j.virusres.2008.01.007_bib38","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1128\/JVI.69.2.669-674.1995","article-title":"Retroviral recombination can lead to linkage of reverse transcriptase mutations that confer increased zidovudine resistance","volume":"69","author":"Kellam","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib39","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.virusres.2006.03.007","article-title":"Risk of HIV-1 transmission by breastfeeding among mothers infected with recombinant and non-recombinant HIV-1 genotypes","volume":"120","author":"Koulinska","year":"2006","journal-title":"Virus Res."},{"key":"10.1016\/j.virusres.2008.01.007_bib40","doi-asserted-by":"crossref","first-page":"8807","DOI":"10.1128\/JVI.02706-05","article-title":"Role of the envelope genetic context in the development of enfuvirtide resistance in human immunodeficiency virus type 1-infected patients","volume":"80","author":"Labrosse","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib41","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1128\/JVI.01659-06","article-title":"Impact of natural polymorphism within the gp41 cytoplasmic tail of human immunodeficiency virus type 1 on the intracellular distribution of envelope glycoproteins and viral assembly","volume":"81","author":"Lambele","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1054-3589(07)55001-5","article-title":"HIV-1 RNA packaging","volume":"55","author":"Lever","year":"2007","journal-title":"Adv. Pharmacol."},{"key":"10.1016\/j.virusres.2008.01.007_bib43","doi-asserted-by":"crossref","first-page":"4204","DOI":"10.1073\/pnas.0306764101","article-title":"Dynamics of HIV-1 recombination in its natural target cells","volume":"101","author":"Levy","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.virusres.2008.01.007_bib44","doi-asserted-by":"crossref","first-page":"10674","DOI":"10.1128\/JVI.76.21.10674-10684.2002","article-title":"Selection for human immunodeficiency virus type 1 recombinants in a patient with rapid progression to AIDS","volume":"76","author":"Liu","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib45","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1099\/vir.0.19180-0","article-title":"In vivo characteristics of human immunodeficiency virus type 1 intersubtype recombination: determination of hot spots and correlation with sequence similarity","volume":"84","author":"Magiorkinis","year":"2003","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib46","doi-asserted-by":"crossref","first-page":"5087","DOI":"10.1128\/JVI.69.8.5087-5094.1995","article-title":"Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase","volume":"69","author":"Mansky","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib47","doi-asserted-by":"crossref","first-page":"15973","DOI":"10.1074\/jbc.M212306200","article-title":"Evidence for a mechanism of recombination during reverse transcription dependent on the structure of the acceptor RNA","volume":"278","author":"Moumen","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2008.01.007_bib48","doi-asserted-by":"crossref","first-page":"6106","DOI":"10.1073\/pnas.93.12.6106","article-title":"Recombination leads to the rapid emergence of HIV-1 dually resistant mutants under selective drug pressure","volume":"93","author":"Moutouh","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.virusres.2008.01.007_bib49","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1742-4690-1-9","article-title":"Early steps of retrovirus replicative cycle","volume":"1","author":"Nisole","year":"2004","journal-title":"Retrovirology"},{"key":"10.1016\/j.virusres.2008.01.007_bib50","doi-asserted-by":"crossref","first-page":"7620","DOI":"10.1128\/JVI.00083-07","article-title":"Contribution of recombination to the evolution of human immunodeficiency viruses expressing resistance to antiretroviral treatment","volume":"81","author":"Nora","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib51","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/00002030-200003100-00019","article-title":"Maternal plasma viral RNA levels determine marked differences in mother-to-child transmission rates of HIV-1 and HIV-2 in The Gambia. MRC\/Gambia Government\/University College London Medical School working group on mother-child transmission of HIV","volume":"14","author":"O\u2019Donovan","year":"2000","journal-title":"AIDS"},{"key":"10.1016\/j.virusres.2008.01.007_bib52","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1097\/00002030-200003100-00018","article-title":"Maternal HIV-1 and HIV-2 infection and child survival in The Gambia","volume":"14","author":"Ota","year":"2000","journal-title":"AIDS"},{"key":"10.1016\/j.virusres.2008.01.007_bib53","doi-asserted-by":"crossref","first-page":"7368","DOI":"10.1128\/JVI.73.9.7368-7375.1999","article-title":"Characterization of a highly replicative intergroup M\/O human immunodeficiency virus type 1 recombinant isolated from a Cameroonian patient","volume":"73","author":"Peeters","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib54","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1086\/386307","article-title":"Minor mutations in HIV protease at baseline and appearance of primary mutation 90M in patients for whom their first protease-inhibitor antiretroviral regimens failed","volume":"189","author":"Perno","year":"2004","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virusres.2008.01.007_bib55","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1600-065X.1999.tb01282.x","article-title":"The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors","volume":"168","author":"Piguet","year":"1999","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.virusres.2008.01.007_bib56","doi-asserted-by":"crossref","first-page":"9600","DOI":"10.1128\/JVI.76.19.9600-9613.2002","article-title":"In vitro intersubtype recombinants of human immunodeficiency virus type 1: comparison to recent and circulating in vivo recombinant forms","volume":"76","author":"Quinones-Mateu","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib57","doi-asserted-by":"crossref","first-page":"46900","DOI":"10.1074\/jbc.M208638200","article-title":"Strand transfer occurs in retroviruses by a pause-initiated two-step mechanism","volume":"277","author":"Roda","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2008.01.007_bib58","doi-asserted-by":"crossref","first-page":"4492","DOI":"10.1128\/JVI.02050-06","article-title":"Extensive intrasubtype recombination in South African human immunodeficiency virus type 1 subtype C infections","volume":"81","author":"Rousseau","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib59","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1097\/00042560-200007010-00011","article-title":"Lower HIV-2 plasma viral loads may explain differences between the natural histories of HIV-1 and HIV-2 infections","volume":"24","author":"Shanmugam","year":"2000","journal-title":"J. Acquir. Immune Defic. Syndr."},{"key":"10.1016\/j.virusres.2008.01.007_bib60","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1534\/genetics.166.3.1155","article-title":"Influence of random genetic drift on human immunodeficiency virus type 1 env evolution during chronic infection","volume":"166","author":"Shriner","year":"2004","journal-title":"Genetics"},{"key":"10.1016\/j.virusres.2008.01.007_bib61","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1126\/science.1371365","article-title":"Mechanism of transduction by retroviruses","volume":"255","author":"Swain","year":"1992","journal-title":"Science"},{"key":"10.1016\/j.virusres.2008.01.007_bib62","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1073\/pnas.80.9.2519","article-title":"Transduction of a cellular oncogene: the genesis of Rous sarcoma virus","volume":"80","author":"Swanstrom","year":"1983","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.virusres.2008.01.007_bib63","doi-asserted-by":"crossref","first-page":"6810","DOI":"10.1128\/JVI.73.8.6810-6820.1999","article-title":"Human immunodeficiency virus type 1 intergroup (M\/O) recombination in Cameroon","volume":"73","author":"Takehisa","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib64","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1038\/444164a","article-title":"Human immunodeficiency viruses: SIV infection in wild gorillas","volume":"444","author":"Van Heuverswyn","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2008.01.007_bib65","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/nature01470","article-title":"Antibody neutralization and escape by HIV-1","volume":"422","author":"Wei","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2008.01.007_bib66","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1074\/jbc.270.1.325","article-title":"Strand transfer mediated by human immunodeficiency virus reverse transcriptase in vitro is promoted by pausing and results in misincorporation","volume":"270","author":"Wu","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2008.01.007_bib67","doi-asserted-by":"crossref","first-page":"28384","DOI":"10.1074\/jbc.273.43.28384","article-title":"The nature of human immunodeficiency virus type 1 strand transfers","volume":"273","author":"Yu","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2008.01.007_bib68","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0166-3542(97)00053-3","article-title":"HIV-1 acquires resistance to two classes of antiviral drugs through homologous recombination","volume":"36","author":"Yusa","year":"1997","journal-title":"Antiviral Res."},{"key":"10.1016\/j.virusres.2008.01.007_bib69","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1128\/JVI.74.5.2313-2322.2000","article-title":"Most retroviral recombinations occur during minus-strand DNA synthesis","volume":"74","author":"Zhang","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2008.01.007_bib70","doi-asserted-by":"crossref","first-page":"11273","DOI":"10.1128\/JVI.76.22.11273-11282.2002","article-title":"Human immunodeficiency virus type 1 recombination: rate, fidelity, and putative hot spots","volume":"76","author":"Zhuang","year":"2002","journal-title":"J. Virol."}],"container-title":["Virus Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170208000270?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170208000270?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,5]],"date-time":"2021-09-05T08:20:11Z","timestamp":1630830011000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168170208000270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6]]},"references-count":70,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["S0168170208000270"],"URL":"https:\/\/doi.org\/10.1016\/j.virusres.2008.01.007","relation":{},"ISSN":["0168-1702"],"issn-type":[{"value":"0168-1702","type":"print"}],"subject":[],"published":{"date-parts":[[2008,6]]}}}