{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:27:50Z","timestamp":1792801670893,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Virus Research"],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1016\/j.virusres.2008.02.008","type":"journal-article","created":{"date-parts":[[2008,4,11]],"date-time":"2008-04-11T19:19:05Z","timestamp":1207941545000},"page":"64-71","source":"Crossref","is-referenced-by-count":66,"title":["DC-SIGN enhances infection of cells with glycosylated West Nile virus in vitro and virus replication in human dendritic cells induces production of IFN-\u03b1 and TNF-\u03b1"],"prefix":"10.1016","volume":"135","author":[{"given":"Byron E.E.","family":"Martina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penelopie","family":"Koraka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"van den Doel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guus F.","family":"Rimmelzwaan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart L.","family":"Haagmans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert D.M.E.","family":"Osterhaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.virusres.2008.02.008_bib1","doi-asserted-by":"crossref","first-page":"3605","DOI":"10.1182\/blood-2004-05-1952","article-title":"Uptake and presentation of hepatitis C virus-like particles by human dendritic cells","volume":"105","author":"Barth","year":"2005","journal-title":"Blood"},{"issue":"24","key":"10.1016\/j.virusres.2008.02.008_bib2","doi-asserted-by":"crossref","first-page":"13097","DOI":"10.1128\/JVI.76.24.13097-13100.2002","article-title":"Identification of neutralizing epitopes within structural domain III of the West Nile virus envelope protein","volume":"76","author":"Beasley","year":"2002","journal-title":"J. Virol."},{"issue":"Suppl. 18","key":"10.1016\/j.virusres.2008.02.008_bib3","first-page":"35","article-title":"Molecular determinants of virulence of West Nile virus in North America","author":"Beasley","year":"2004","journal-title":"Arch. Virol."},{"issue":"1","key":"10.1016\/j.virusres.2008.02.008_bib4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1006\/viro.2002.1372","article-title":"Mouse neuroinvasive phenotype of West Nile virus strains varies depending upon virus genotype","volume":"296","author":"Beasley","year":"2002","journal-title":"Virology"},{"issue":"13","key":"10.1016\/j.virusres.2008.02.008_bib5","doi-asserted-by":"crossref","first-page":"8339","DOI":"10.1128\/JVI.79.13.8339-8347.2005","article-title":"Envelope protein glycosylation status influences mouse neuroinvasion phenotype of genetic lineage 1 West Nile virus strains","volume":"79","author":"Beasley","year":"2005","journal-title":"J. Virol."},{"issue":"Pt 9","key":"10.1016\/j.virusres.2008.02.008_bib6","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1099\/0022-1317-78-9-2293","article-title":"Extensive nucleotide changes and deletions within the envelope glycoprotein gene of Euro-African West Nile viruses","volume":"78","author":"Berthet","year":"1997","journal-title":"J. Gen. Virol."},{"issue":"9","key":"10.1016\/j.virusres.2008.02.008_bib7","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S1473-3099(02)00368-7","article-title":"West Nile virus","volume":"2","author":"Campbell","year":"2002","journal-title":"Lancet Infect. Dis."},{"issue":"2","key":"10.1016\/j.virusres.2008.02.008_bib8","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0042-6822(03)00536-1","article-title":"Evolutionary relationship between Old World West Nile virus strains. Evidence for viral gene flow between Africa, the Middle East, and Europe","volume":"315","author":"Charrel","year":"2003","journal-title":"Virology"},{"issue":"3","key":"10.1016\/j.virusres.2008.02.008_bib9","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1128\/JVI.80.3.1290-1301.2006","article-title":"West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection","volume":"80","author":"Davis","year":"2006","journal-title":"J. Virol."},{"issue":"7","key":"10.1016\/j.virusres.2008.02.008_bib10","doi-asserted-by":"crossref","first-page":"3477","DOI":"10.1128\/JVI.80.7.3477-3486.2006","article-title":"Measles virus targets DC-SIGN to enhance dendritic cell infection","volume":"80","author":"de Witte","year":"2006","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.virusres.2008.02.008_bib11","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1089\/vbz.2006.0586","article-title":"Clinical and pathologic features of lineage 2 West Nile virus infections in birds of prey in Hungary","volume":"7","author":"Erdelyi","year":"2007","journal-title":"Vector Borne Zoonotic Dis."},{"issue":"11","key":"10.1016\/j.virusres.2008.02.008_bib12","doi-asserted-by":"crossref","first-page":"4096","DOI":"10.1128\/JCM.38.11.4096-4101.2000","article-title":"Detection of influenza A viruses from different species by PCR amplification of conserved sequences in the matrix gene","volume":"38","author":"Fouchier","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.virusres.2008.02.008_bib13","article-title":"Evidence that multiple defects in murine DC-SIGN inhibit a functional interaction with pathogens","author":"Gramberg","year":"2005","journal-title":"Virology"},{"issue":"9","key":"10.1016\/j.virusres.2008.02.008_bib14","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S1473-3099(04)01128-4","article-title":"West Nile virus: where are we now?","volume":"4","author":"Granwehr","year":"2004","journal-title":"Lancet Infect. Dis."},{"issue":"5","key":"10.1016\/j.virusres.2008.02.008_bib15","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S1074-7613(02)00447-8","article-title":"Human cytomegalovirus binding to DC-SIGN is required for dendritic cell infection and target cell trans-infection","volume":"17","author":"Halary","year":"2002","journal-title":"Immunity"},{"issue":"21","key":"10.1016\/j.virusres.2008.02.008_bib16","doi-asserted-by":"crossref","first-page":"13262","DOI":"10.1128\/JVI.79.21.13262-13274.2005","article-title":"N-linked glycosylation of west nile virus envelope proteins influences particle assembly and infectivity","volume":"79","author":"Hanna","year":"2005","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.virusres.2008.02.008_bib17","doi-asserted-by":"crossref","first-page":"748","DOI":"10.3201\/eid0704.010428","article-title":"Isolation and characterization of West Nile virus from the blood of viremic patients during the 2000 outbreak in Israel","volume":"7","author":"Hindiyeh","year":"2001","journal-title":"Emerg. Infect. Dis."},{"issue":"7","key":"10.1016\/j.virusres.2008.02.008_bib18","doi-asserted-by":"crossref","first-page":"4761","DOI":"10.1128\/JVI.70.7.4761-4766.1996","article-title":"Phenotypic changes in Langerhans\u2019 cells after infection with arboviruses: a role in the immune response to epidermally acquired viral infection?","volume":"70","author":"Johnston","year":"1996","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virusres.2008.02.008_bib19","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1006\/viro.2002.1449","article-title":"Complete genome sequences and phylogenetic analysis of West Nile virus strains isolated from the United States, Europe, and the Middle East","volume":"298","author":"Lanciotti","year":"2002","journal-title":"Virology"},{"issue":"5448","key":"10.1016\/j.virusres.2008.02.008_bib20","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1126\/science.286.5448.2333","article-title":"Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States","volume":"286","author":"Lanciotti","year":"1999","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.virusres.2008.02.008_bib21","doi-asserted-by":"crossref","first-page":"3501","DOI":"10.1128\/JVI.75.8.3501-3508.2001","article-title":"Human dendritic cells are activated by dengue virus infection: enhancement by gamma interferon and implications for disease pathogenesis","volume":"75","author":"Libraty","year":"2001","journal-title":"J. Virol."},{"issue":"25","key":"10.1016\/j.virusres.2008.02.008_bib22","doi-asserted-by":"crossref","first-page":"23698","DOI":"10.1074\/jbc.M504337200","article-title":"Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals","volume":"280","author":"Lozach","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.virusres.2008.02.008_bib23","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1128\/JVI.74.2.914-922.2000","article-title":"Role of dendritic cell targeting in Venezuelan equine encephalitis virus pathogenesis","volume":"74","author":"MacDonald","year":"2000","journal-title":"J. Virol."},{"issue":"7","key":"10.1016\/j.virusres.2008.02.008_bib24","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/sj.embor.embor866","article-title":"Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses","volume":"4","author":"Navarro-Sanchez","year":"2003","journal-title":"EMBO Rep."},{"issue":"Pt 6","key":"10.1016\/j.virusres.2008.02.008_bib25","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1099\/vir.0.80852-0","article-title":"Infection of mature dendritic cells with herpes simplex virus type 1 dramatically reduces lymphoid chemokine-mediated migration","volume":"86","author":"Prechtel","year":"2005","journal-title":"J. Gen. Virol."},{"issue":"4","key":"10.1016\/j.virusres.2008.02.008_bib26","doi-asserted-by":"crossref","first-page":"600","DOI":"10.4269\/ajtmh.1999.61.600","article-title":"Entomologic and avian investigations of an epidemic of West Nile fever in Romania in 1996, with serologic and molecular characterization of a virus isolate from mosquitoes","volume":"61","author":"Savage","year":"1999","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.virusres.2008.02.008_bib27","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1749-6632.2001.tb02719.x","article-title":"Biological significance of glycosylation of the envelope protein of Kunjin virus","volume":"951","author":"Scherret","year":"2001","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"Pt 12","key":"10.1016\/j.virusres.2008.02.008_bib28","doi-asserted-by":"crossref","first-page":"3637","DOI":"10.1099\/vir.0.80247-0","article-title":"Viral envelope protein glycosylation is a molecular determinant of the neuroinvasiveness of the New York strain of West Nile virus","volume":"85","author":"Shirato","year":"2004","journal-title":"J. Gen. Virol."},{"issue":"24","key":"10.1016\/j.virusres.2008.02.008_bib29","doi-asserted-by":"crossref","first-page":"13640","DOI":"10.1128\/JVI.00857-07","article-title":"Differential activation of human monocyte-derived and plasmacytoid dendritic cells by West Nile virus generated in different host cells","volume":"81","author":"Silva","year":"2007","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virusres.2008.02.008_bib30","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1084\/jem.20021468","article-title":"DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells","volume":"197","author":"Tailleux","year":"2003","journal-title":"J. Exp. Med."},{"issue":"6","key":"10.1016\/j.virusres.2008.02.008_bib31","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1128\/JVI.78.6.2943-2947.2004","article-title":"Human macrophage C-type lectin specific for galactose and N-acetylgalactosamine promotes filovirus entry","volume":"78","author":"Takada","year":"2004","journal-title":"J. Virol."},{"issue":"7","key":"10.1016\/j.virusres.2008.02.008_bib32","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1084\/jem.20021840","article-title":"DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells","volume":"197","author":"Tassaneetrithep","year":"2003","journal-title":"J. Exp. Med."},{"issue":"37","key":"10.1016\/j.virusres.2008.02.008_bib33","doi-asserted-by":"crossref","first-page":"38755","DOI":"10.1074\/jbc.M402385200","article-title":"Solution structure and antibody binding studies of the envelope protein domain III from the New York strain of West Nile virus","volume":"279","author":"Volk","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"7","key":"10.1016\/j.virusres.2008.02.008_bib34","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/77553","article-title":"Human skin Langerhans cells are targets of dengue virus infection","volume":"6","author":"Wu","year":"2000","journal-title":"Nat. Med."},{"issue":"10","key":"10.1016\/j.virusres.2008.02.008_bib35","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1086\/429673","article-title":"DC-SIGN-mediated transfer of HIV-1 is compromised by the ability of Leishmania infantum to exploit DC-SIGN as a ligand","volume":"191","author":"Zhao","year":"2005","journal-title":"J. Infect. Dis."}],"container-title":["Virus Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170208000683?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170208000683?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,4]],"date-time":"2020-05-04T04:42:54Z","timestamp":1588567374000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168170208000683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["S0168170208000683"],"URL":"https:\/\/doi.org\/10.1016\/j.virusres.2008.02.008","relation":{},"ISSN":["0168-1702"],"issn-type":[{"value":"0168-1702","type":"print"}],"subject":[],"published":{"date-parts":[[2008,7]]}}}