{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T16:20:49Z","timestamp":1793118049767,"version":"4.5.0"},"reference-count":55,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000199","name":"USDA","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Nebraska Center for Virology","award":["1P20RR15635"],"award-info":[{"award-number":["1P20RR15635"]}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"crossref"}]},{"name":"NIH"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Virus Research"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.virusres.2011.06.003","type":"journal-article","created":{"date-parts":[[2011,6,24]],"date-time":"2011-06-24T14:04:12Z","timestamp":1308924252000},"page":"143-149","source":"Crossref","is-referenced-by-count":15,"title":["Cytoplasmic localized infected cell protein 0 (bICP0) encoded by bovine herpesvirus 1 inhibits \u03b2 interferon promoter activity and reduces IRF3 (interferon response factor 3) protein levels"],"prefix":"10.1016","volume":"160","author":[{"given":"Leticia Frizzo","family":"da Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha","family":"Gaudreault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clinton","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virusres.2011.06.003_bib0005","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1089\/107999002753452665","article-title":"On the control of IRF in host defense","volume":"22","author":"Barnes","year":"2002","journal-title":"J. Interferon Cytokine Res."},{"issue":"38","key":"10.1016\/j.virusres.2011.06.003_bib0010","doi-asserted-by":"crossref","first-page":"36596","DOI":"10.1074\/jbc.M300776200","article-title":"The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with an ubiquitinates p53","volume":"278","author":"Boutell","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2011.06.003_bib0015","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1128\/JVI.76.2.841-850.2002","article-title":"Herpes simplex virus type 1 immediate-early protein ICP0 and its isolated RING finger domain act as ubiquitin E3 ligases in vitro","volume":"76","author":"Boutell","year":"2002","journal-title":"J. Virol."},{"issue":"7","key":"10.1016\/j.virusres.2011.06.003_bib0020","doi-asserted-by":"crossref","first-page":"4904","DOI":"10.1128\/JVI.71.7.4904-4914.1997","article-title":"The ICP0 protein of equine herpesvirus 1 is an early protein that independently transactivates expression of all classes of viral promoters","volume":"71","author":"Bowles","year":"1997","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.virusres.2011.06.003_bib0025","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1128\/JVI.74.3.1200-1208.2000","article-title":"Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein","volume":"74","author":"Bowles","year":"2000","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.virusres.2011.06.003_bib0030","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1128\/JVI.63.4.1525-1530.1989","article-title":"Inhibition of T-lymphocyte mitogenic responses and effects on cell functions by bovine herpesvirus 1","volume":"63","author":"Carter","year":"1989","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2011.06.003_bib0035","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.virusres.2011.02.004","article-title":"Infection of cultured bovine cells with bovine herpesvirus 1 (BHV-1) or Sendai virus induces different beta interferon subtypes","volume":"157","author":"da Silva","year":"2011","journal-title":"Virus Res."},{"key":"10.1016\/j.virusres.2011.06.003_bib0040","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.cellsig.2004.07.003","article-title":"Herpes virus proteins ICP0 and BICP0 can activate NF-kB by catalyzing IkBa ubiquitination","volume":"17","author":"Dia","year":"2005","journal-title":"Cell. Signal."},{"key":"10.1016\/j.virusres.2011.06.003_bib0045","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S1074-7613(02)00390-4","article-title":"IRF3 mediates a TLR3\/TLR4-specific antiviral gene program","volume":"17","author":"Doyle","year":"2002","journal-title":"Immunity"},{"issue":"11","key":"10.1016\/j.virusres.2011.06.003_bib0050","doi-asserted-by":"crossref","first-page":"7339","DOI":"10.1128\/JVI.69.11.7339-7344.1995","article-title":"Point mutations in the herpes simplex virus type 1 Vmw110 RING finger helix affect activation of gene expression, viral growth, and interaction with PML-containing nuclear structures","volume":"69","author":"Everett","year":"1995","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virusres.2011.06.003_bib0055","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0022-2836(88)90521-9","article-title":"Analysis of the functional domains of herpes simplex virus type 1 immediate-early polypeptide Vmw110","volume":"202","author":"Everett","year":"1988","journal-title":"J. Mol. Biol."},{"issue":"8","key":"10.1016\/j.virusres.2011.06.003_bib0060","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1002\/1521-1878(200008)22:8<761::AID-BIES10>3.0.CO;2-A","article-title":"ICP0, a regulator of herpes simplex virus during lytic and latent infection","volume":"22","author":"Everett","year":"2000","journal-title":"Bioessays"},{"issue":"4","key":"10.1016\/j.virusres.2011.06.003_bib0065","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1006\/jmbi.1993.1657","article-title":"A novel arrangement of zinc-binding residues and secondary structure in the C3HC4 motif of an alpha herpes virus protein family","volume":"234","author":"Everett","year":"1993","journal-title":"J. Mol. Biol."},{"issue":"6","key":"10.1016\/j.virusres.2011.06.003_bib0070","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1093\/emboj\/18.6.1526","article-title":"Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110","volume":"18","author":"Everett","year":"1999","journal-title":"EMBO J."},{"issue":"Pt 24","key":"10.1016\/j.virusres.2011.06.003_bib0075","doi-asserted-by":"crossref","first-page":"4581","DOI":"10.1242\/jcs.112.24.4581","article-title":"Cell cycle regulation of PML modification and ND10 composition","volume":"112","author":"Everett","year":"1999","journal-title":"J. Cell Sci."},{"issue":"7","key":"10.1016\/j.virusres.2011.06.003_bib0080","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1093\/emboj\/16.7.1519","article-title":"A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein [corrected and republished article originally printed in EMBO J 1997 Feb 3;16(3):566\u201377]","volume":"16","author":"Everett","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/j.virusres.2011.06.003_bib0085","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.biochi.2007.01.004","article-title":"PML and PML nuclear bodies: implications in antiviral defence","volume":"74","author":"Everett","year":"2007","journal-title":"Biochemie"},{"issue":"2","key":"10.1016\/j.virusres.2011.06.003_bib0090","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1002\/jcb.22700","article-title":"2,3,7,8-Tetrachlorodibenzo-p-dioxin modifies expression and nuclear\/cytosolic localization of bovine herpesvirus 1 immediate-early protein (bICP0) during infection","volume":"111","author":"Fiorito","year":"2009","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.virusres.2011.06.003_bib0095","first-page":"491","article-title":"IKKe and TBKI are essential components of the IRF3 signaling pathway","volume":"4","author":"Fitzgerald","year":"2003","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.virusres.2011.06.003_bib0100","doi-asserted-by":"crossref","first-page":"3154","DOI":"10.1128\/JVI.68.5.3154-3162.1994","article-title":"Identification and zinc dependence of the bovine herpesvirus 1 transactivator protein BICP0","volume":"68","author":"Fraefel","year":"1994","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2011.06.003_bib0105","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.virusres.2010.12.010","article-title":"Regulation of promyelocytic leukemia (PML) protein levels and cell morphology by bovine herpesvirus 1 infected cell protein 0 (bICP0) and mutant bICP0 proteins that do not localize to the nucleus","volume":"156","author":"Gaudreault","year":"2011","journal-title":"Virus Res."},{"key":"10.1016\/j.virusres.2011.06.003_bib0110","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1126\/science.1189157","article-title":"PML regulates apoptosis at endoplasmic reticulum by modulating calcium release","volume":"330","author":"Giorgi","year":"2010","journal-title":"Science"},{"issue":"Pt 2","key":"10.1016\/j.virusres.2011.06.003_bib0115","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1099\/0022-1317-71-2-369","article-title":"The interaction between bovine herpesvirus type 1 and activated bovine T lymphocytes","volume":"71","author":"Griebel","year":"1990","journal-title":"J. Gen. Virol."},{"issue":"4","key":"10.1016\/j.virusres.2011.06.003_bib0120","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1089\/vim.1987.1.287","article-title":"T lymphocyte population dynamics and function following a primary bovine herpesvirus type-1 infection","volume":"1","author":"Griebel","year":"1987","journal-title":"Viral Immunol."},{"issue":"4","key":"10.1016\/j.virusres.2011.06.003_bib0125","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1089\/vim.1987.1.267","article-title":"Bovine peripheral blood leukocyte subpopulation dynamics following a primary bovine herpesvirus-1 infection","volume":"1","author":"Griebel","year":"1987","journal-title":"Viral Immunol."},{"issue":"4","key":"10.1016\/j.virusres.2011.06.003_bib0130","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1089\/vim.1993.6.273","article-title":"Down regulation of murine MHC class I expression by bovine herpesvirus 1","volume":"6","author":"Hariharan","year":"1993","journal-title":"Viral Immunol."},{"key":"10.1016\/j.virusres.2011.06.003_bib0135","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1099\/vir.0.81109-0","article-title":"The bovine herpesvirus 1 gene encoding infected cell protein 0 (bICP0) can inhibit interferon-dependent transcription in the absence of other viral genes","volume":"86","author":"Henderson","year":"2005","journal-title":"J. Gen. Virol."},{"issue":"1","key":"10.1016\/j.virusres.2011.06.003_bib0140","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0168-1702(97)00128-7","article-title":"Bovine herpesvirus-1 infection affects the peptide transport activity in bovine cells","volume":"53","author":"Hinkley","year":"1998","journal-title":"Virus Res."},{"key":"10.1016\/j.virusres.2011.06.003_bib0145","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1038\/nature03464","article-title":"IRF-7 is the master regulator of type-I interferon-dependent immune responses","volume":"434","author":"Honda","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2011.06.003_bib0150","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1099\/0022-1317-82-3-483","article-title":"The zinc ring finger in the bICP0 protein encoded by bovine herpes virus-1 mediates toxicity and activates productive infection","volume":"82","author":"Inman","year":"2001","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virusres.2011.06.003_bib0155","doi-asserted-by":"crossref","first-page":"255","DOI":"10.3390\/v1020255","article-title":"Regulation of innate immune responses by bovine herpesvirus 1 and infected cell protein 0","volume":"1","author":"Jones","year":"2009","journal-title":"Viruses"},{"issue":"2","key":"10.1016\/j.virusres.2011.06.003_bib0160","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1017\/S146625230700134X","article-title":"A review of the biology of bovine herpesvirus type 1 (BHV-1), its role as a cofactor in the bovine respiratory disease complex and development of improved vaccines","volume":"8","author":"Jones","year":"2007","journal-title":"Anim. Health Res. Rev."},{"key":"10.1016\/j.virusres.2011.06.003_bib0165","doi-asserted-by":"crossref","first-page":"4222","DOI":"10.1128\/JVI.02585-09","article-title":"Role of the herpes simplex virus ICP0 in the transactivation of genes introduced by infection or transfection: a reappraisal","volume":"84","author":"Kalamvoki","year":"2010","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.virusres.2011.06.003_bib0170","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1128\/JVI.71.2.1019-1024.1997","article-title":"Interaction of herpes simplex virus 1 alpha regulatory protein ICP0 with elongation factor 1delta: ICP0 affects translational machinery","volume":"71","author":"Kawaguchi","year":"1997","journal-title":"J. Virol."},{"issue":"11","key":"10.1016\/j.virusres.2011.06.003_bib0175","doi-asserted-by":"crossref","first-page":"7471","DOI":"10.1128\/JVI.70.11.7471-7477.1996","article-title":"Attenuation of DNA-dependent protein kinase activity and its catalytic subunit by the herpes simplex virus type 1 transactivator ICP0","volume":"70","author":"Lees-Miller","year":"1996","journal-title":"J. Virol."},{"issue":"11","key":"10.1016\/j.virusres.2011.06.003_bib0180","doi-asserted-by":"crossref","first-page":"8602","DOI":"10.1128\/JVI.71.11.8602-8614.1997","article-title":"Mutational analysis of the herpes simplex virus type 1 ICP0 C3HC4 zinc ring finger reveals a requirement for ICP0 in the expression of the essential alpha27 gene","volume":"71","author":"Lium","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2011.06.003_bib0185","doi-asserted-by":"crossref","first-page":"3832","DOI":"10.1128\/JVI.75.8.3832-3840.2001","article-title":"Requirements for the nuclear-cytoplasmic translocation of infected-cell protein 0 of herpes simplex virus type 1","volume":"75","author":"Lopez","year":"2001","journal-title":"J. Virol."},{"issue":"Pt 6","key":"10.1016\/j.virusres.2011.06.003_bib0190","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1099\/0022-1317-75-6-1223","article-title":"The nuclear location of PML, a cellular member of the C3HC4 zinc-binding domain protein family, is rearranged during herpes simplex virus infection by the C3HC4 viral protein ICP0","volume":"75","author":"Maul","year":"1994","journal-title":"J. Gen. Virol."},{"issue":"Pt 12","key":"10.1016\/j.virusres.2011.06.003_bib0195","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1099\/0022-1317-74-12-2679","article-title":"Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0)","volume":"74","author":"Maul","year":"1993","journal-title":"J. Gen. Virol."},{"issue":"1","key":"10.1016\/j.virusres.2011.06.003_bib0200","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1089\/vim.1997.10.21","article-title":"Bovine herpesvirus 1 downregulates the expression of bovine MHC class I molecules","volume":"10","author":"Nataraj","year":"1997","journal-title":"Viral Immunol."},{"key":"10.1016\/j.virusres.2011.06.003_bib0205","doi-asserted-by":"crossref","first-page":"e10428","DOI":"10.1371\/journal.pone.0010428","article-title":"Cellular localization of the herpes simplex virus ICP0 protein dictates its ability to block IRF-3 mediated innate immune responses","volume":"5","author":"Paladino","year":"2010","journal-title":"PLOS One"},{"issue":"21","key":"10.1016\/j.virusres.2011.06.003_bib0210","doi-asserted-by":"crossref","first-page":"10006","DOI":"10.1128\/JVI.74.21.10006-10017.2000","article-title":"Alphaherpesvirus proteins related to herpes simplex virus type 1 ICP0 affect cellular structures and proteins","volume":"74","author":"Parkinson","year":"2000","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virusres.2011.06.003_bib0215","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1128\/JVI.73.1.650-657.1999","article-title":"Herpes simplex virus type 1 immediate-early protein vmw110 induces the proteasome-dependent degradation of the catalytic subunit of DNA-dependent protein kinase","volume":"73","author":"Parkinson","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2011.06.003_bib0220","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1099\/vir.0.83481-0","article-title":"Premature expression of the latency-related RNA encoded by bovine herpesvirus 1 correlates with higher levels of beta interferon RNA expression in productively infected cells","volume":"89","author":"Perez","year":"2008","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virusres.2011.06.003_bib0230","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1128\/JVI.02064-06","article-title":"The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) induces degradation of interferon response factor 3 (IRF3), and consequently inhibits beta interferon promoter activity","volume":"81","author":"Saira","year":"2007","journal-title":"J. Virol."},{"issue":"8","key":"10.1016\/j.virusres.2011.06.003_bib0240","doi-asserted-by":"crossref","first-page":"3977","DOI":"10.1128\/JVI.02400-08","article-title":"The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) associates with interferon regulatory factor 7 and consequently inhibits beta interferon promoter activity","volume":"83","author":"Saira","year":"2009","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2011.06.003_bib0250","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1089\/107999002753452656","article-title":"Overlapping and distinct mechanisms regulating IRF-3 and IRF-7 function","volume":"22","author":"Servant","year":"2002","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.virusres.2011.06.003_bib0255","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0065-3527(08)60061-5","article-title":"Bovine herpesvirus 1 (BHV-1): biology, pathogenesis, and control","volume":"45","author":"Tikoo","year":"1995","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.virusres.2011.06.003_bib0260","doi-asserted-by":"crossref","first-page":"7325","DOI":"10.1128\/JVI.00723-08","article-title":"Cellular proteins PML and Daxx mediate an innate anitviral defense antagonized by the adenovirus E4 ORF3 protein","volume":"82","author":"Ullman","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2011.06.003_bib0265","doi-asserted-by":"crossref","first-page":"8426","DOI":"10.1128\/JVI.77.15.8426-8439.2003","article-title":"Role of alpha\/beta interferons in the attenuation and immunogenecity of recombinant bovine respiratory syncitial viruses lacking NS proteins","volume":"77","author":"Valarcher","year":"2003","journal-title":"J. Virol."},{"issue":"15","key":"10.1016\/j.virusres.2011.06.003_bib0270","doi-asserted-by":"crossref","first-page":"8815","DOI":"10.1073\/pnas.161283098","article-title":"The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity","volume":"98","author":"Van Sant","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.virusres.2011.06.003_bib0275","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0022-2836(83)80281-2","article-title":"A comparison of vertebrate interferon gene families deteced by hybridization with human interferon DNA","volume":"166","author":"Wilson","year":"1983","journal-title":"J. Mol. Biol."},{"issue":"10","key":"10.1016\/j.virusres.2011.06.003_bib0280","doi-asserted-by":"crossref","first-page":"8657","DOI":"10.1128\/JVI.73.10.8657-8668.1999","article-title":"Bovine herpesvirus 1 can infect CD4(+) T lymphocytes and induce programmed cell death during acute infection of cattle","volume":"73","author":"Winkler","year":"1999","journal-title":"J. Virol."},{"issue":"5","key":"10.1016\/j.virusres.2011.06.003_bib0285","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1128\/JVI.66.5.2763-2772.1992","article-title":"Immediate-early RNA 2.9 and early RNA 2.6 of bovine herpesvirus 1 are 3\u2032 coterminal and encode a putative zinc finger transactivator protein","volume":"66","author":"Wirth","year":"1992","journal-title":"J. Virol."},{"issue":"Pt 4","key":"10.1016\/j.virusres.2011.06.003_bib0295","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1099\/vir.0.80698-0","article-title":"Identification of functional domains within the bICP0 protein encoded by bovine herpesvirus 1","volume":"86","author":"Zhang","year":"2005","journal-title":"J. Gen. Virol."}],"container-title":["Virus Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170211002267?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170211002267?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T11:25:43Z","timestamp":1637925943000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168170211002267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":55,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S0168170211002267"],"URL":"https:\/\/doi.org\/10.1016\/j.virusres.2011.06.003","relation":{},"ISSN":["0168-1702"],"issn-type":[{"value":"0168-1702","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}