{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T22:20:44Z","timestamp":1783981244130,"version":"3.55.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100010042","name":"Special Fund for Agro-Scientific Research in the Public Interest","doi-asserted-by":"crossref","award":["201103032"],"award-info":[{"award-number":["201103032"]}],"id":[{"id":"10.13039\/501100010042","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Natural Science Foundation for Young Scholars","award":["31101791"],"award-info":[{"award-number":["31101791"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Virus Research"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.virusres.2012.07.024","type":"journal-article","created":{"date-parts":[[2012,8,3]],"date-time":"2012-08-03T16:02:15Z","timestamp":1344009735000},"page":"169-174","source":"Crossref","is-referenced-by-count":24,"title":["Small interfering RNAs targeting the rabies virus nucleoprotein gene"],"prefix":"10.1016","volume":"169","author":[{"given":"Yu-Jiao","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping-Sen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua-Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Ru","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Li","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Xia","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tie-Cheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song-Tao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian-Zhu","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virusres.2012.07.024_bib0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/B978-0-12-387040-7.00001-9","article-title":"Rabies virus transcription and replication","volume":"79","author":"Albertini","year":"2011","journal-title":"Advances in Virus Research"},{"issue":"2","key":"10.1016\/j.virusres.2012.07.024_bib0010","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1007\/s00018-007-7298-1","article-title":"Structural aspects of rabies virus replication","volume":"65","author":"Albertini","year":"2008","journal-title":"Cellular and Molecular Life Sciences"},{"issue":"14","key":"10.1016\/j.virusres.2012.07.024_bib0015","doi-asserted-by":"crossref","first-page":"e86","DOI":"10.1093\/nar\/gkn371","article-title":"Efficient delivery of RNA interference to peripheral neurons in vivo using herpes simplex virus","volume":"36","author":"Anesti","year":"2008","journal-title":"Nucleic Acids Research"},{"issue":"1","key":"10.1016\/j.virusres.2012.07.024_bib0020","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/nm1164","article-title":"Inhibition of respiratory viruses by nasally administered siRNA","volume":"11","author":"Bitko","year":"2005","journal-title":"Nature Medicine"},{"issue":"3","key":"10.1016\/j.virusres.2012.07.024_bib0025","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1093\/nar\/gkh278","article-title":"Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins","volume":"32","author":"Boden","year":"2004","journal-title":"Nucleic Acids Research"},{"issue":"2","key":"10.1016\/j.virusres.2012.07.024_bib0030","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1590\/S1413-86702007000200011","article-title":"Short-interfering RNAs as antivirals against rabies","volume":"11","author":"Brandao","year":"2007","journal-title":"Brazilian Journal of Infectious Diseases"},{"issue":"19","key":"10.1016\/j.virusres.2012.07.024_bib0035","doi-asserted-by":"crossref","first-page":"8800","DOI":"10.1073\/pnas.0912186107","article-title":"A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus","volume":"107","author":"DeVincenzo","year":"2010","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"1","key":"10.1016\/j.virusres.2012.07.024_bib0040","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.virusres.2011.08.004","article-title":"Intracerebral delivery of small interfering RNAs (siRNAs) using adenoviral vector protects mice against lethal peripheral rabies challenge","volume":"163","author":"Gupta","year":"2011","journal-title":"Virus Research"},{"issue":"5","key":"10.1016\/j.virusres.2012.07.024_bib0045","doi-asserted-by":"crossref","first-page":"e5731","DOI":"10.1371\/journal.pone.0005731","article-title":"Nora virus persistent infections are not affected by the RNAi machinery","volume":"4","author":"Habayeb","year":"2009","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.virusres.2012.07.024_bib0050","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1080\/13550280600902295","article-title":"Failure of therapeutic coma and ketamine for therapy of human rabies","volume":"12","author":"Hemachudha","year":"2006","journal-title":"Journal of Neurovirology"},{"issue":"1","key":"10.1016\/j.virusres.2012.07.024_bib0055","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.antiviral.2009.07.012","article-title":"Inhibition of rabies virus replication by multiple artificial microRNAs","volume":"84","author":"Israsena","year":"2009","journal-title":"Antiviral Research"},{"issue":"2","key":"10.1016\/j.virusres.2012.07.024_bib0060","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.antiviral.2008.06.001","article-title":"Therapeutic application of RNA interference against foot-and-mouth disease virus in vitro and in vivo","volume":"80","author":"Kim","year":"2008","journal-title":"Antiviral Research"},{"issue":"4","key":"10.1016\/j.virusres.2012.07.024_bib0065","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.cell.2008.06.034","article-title":"T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice","volume":"134","author":"Kumar","year":"2008","journal-title":"Cell"},{"issue":"9","key":"10.1016\/j.virusres.2012.07.024_bib0070","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1038\/nm1280","article-title":"Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque","volume":"11","author":"Li","year":"2005","journal-title":"Nature Medicine"},{"issue":"10","key":"10.1016\/j.virusres.2012.07.024_bib0075","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1038\/mt.2009.176","article-title":"Combinatorial RNAi against HIV-1 using extended short hairpin RNAs","volume":"17","author":"Liu","year":"2009","journal-title":"Molecular Therapy"},{"issue":"3","key":"10.1016\/j.virusres.2012.07.024_bib0080","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.jhep.2007.12.007","article-title":"RNAi: a powerful tool to unravel hepatitis C virus\u2013host interactions within the infectious life cycle","volume":"48","author":"Lupberger","year":"2008","journal-title":"Journal of Hepatology"},{"issue":"6","key":"10.1016\/j.virusres.2012.07.024_bib0085","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/nbt824","article-title":"Inhibition of hepatitis B virus in mice by RNA interference","volume":"21","author":"McCaffrey","year":"2003","journal-title":"Nature Biotechnology"},{"issue":"8","key":"10.1016\/j.virusres.2012.07.024_bib0090","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1038\/nbt1122","article-title":"Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs","volume":"23","author":"Morrissey","year":"2005","journal-title":"Nature Biotechnology"},{"issue":"2","key":"10.1016\/j.virusres.2012.07.024_bib0095","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/j.1525-1438.2006.00384.x","article-title":"Inhibition of HPV 16 E6 oncogene expression by RNA interference in vitro and in vivo","volume":"16","author":"Niu","year":"2006","journal-title":"International Journal of Gynecological Cancer"},{"issue":"2","key":"10.1016\/j.virusres.2012.07.024_bib0100","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1007\/s11262-009-0328-3","article-title":"RNA interference inhibits yellow fever virus replication in vitro and in vivo","volume":"38","author":"Pacca","year":"2009","journal-title":"Virus Genes"},{"issue":"6","key":"10.1016\/j.virusres.2012.07.024_bib0105","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.imbio.2008.11.010","article-title":"RNA interference mediated silencing of Hsp60 gene in human monocytic myeloma cell line U937 revealed decreased dengue virus multiplication","volume":"214","author":"Padwad","year":"2009","journal-title":"Immunobiology"},{"issue":"3","key":"10.1016\/j.virusres.2012.07.024_bib0110","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1637\/0005-2086(2007)51[725:IOSDOV]2.0.CO;2","article-title":"Influence of strain, dose of virus, and age at inoculation on subgroup J avian leukosis virus persistence, antibody response, and oncogenicity in commercial meat-type chickens","volume":"51","author":"Pandiri","year":"2007","journal-title":"Avian Diseases"},{"issue":"1","key":"10.1016\/j.virusres.2012.07.024_bib0115","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.virusres.2004.01.010","article-title":"RNA silencing in viral infections: insights from poliovirus","volume":"102","author":"Saleh","year":"2004","journal-title":"Virus Research"},{"issue":"3","key":"10.1016\/j.virusres.2012.07.024_bib0120","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nm828","article-title":"RNA interference targeting Fas protects mice from fulminant hepatitis","volume":"9","author":"Song","year":"2003","journal-title":"Nature Medicine"},{"issue":"1","key":"10.1016\/j.virusres.2012.07.024_bib0125","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.rvsc.2011.06.008","article-title":"Inhibition of rabies virus multiplication by siRNA delivered through adenoviral vector in vitro in BHK-21 cells and in vivo in mice","volume":"93","author":"Sonwane","year":"2012","journal-title":"Research in Veterinary Science"},{"issue":"24","key":"10.1016\/j.virusres.2012.07.024_bib0130","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1056\/NEJMoa050382","article-title":"Survival after treatment of rabies with induction of coma","volume":"352","author":"Willoughby","year":"2005","journal-title":"New England Journal of Medicine"},{"issue":"8","key":"10.1016\/j.virusres.2012.07.024_bib0135","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1007\/s00705-004-0299-6","article-title":"Selection of genetic inhibitors of rabies virus","volume":"149","author":"Wunner","year":"2004","journal-title":"Archives of Virology"},{"issue":"3","key":"10.1016\/j.virusres.2012.07.024_bib0140","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.bbrc.2009.09.039","article-title":"Inhibition of highly pathogenic avian influenza virus H5N1 replication by the small interfering RNA targeting polymerase A gene","volume":"390","author":"Zhang","year":"2009","journal-title":"Biochemical and Biophysical Research Communications"}],"container-title":["Virus Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170212002900?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170212002900?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T04:43:36Z","timestamp":1588826616000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168170212002900"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0168170212002900"],"URL":"https:\/\/doi.org\/10.1016\/j.virusres.2012.07.024","relation":{},"ISSN":["0168-1702"],"issn-type":[{"value":"0168-1702","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}