{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T11:58:30Z","timestamp":1777550310626,"version":"3.51.4"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virus Research"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.virusres.2015.08.010","type":"journal-article","created":{"date-parts":[[2015,8,12]],"date-time":"2015-08-12T13:46:43Z","timestamp":1439387203000},"page":"227-231","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Ex vivo modeling of feline herpesvirus replication in ocular and respiratory mucosae, the primary targets of infection"],"prefix":"10.1016","volume":"210","author":[{"given":"Yewei","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jolien","family":"Van Cleemput","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishwanatha R.A.P.","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bart","family":"Mateusen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans J.","family":"Nauwynck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.virusres.2015.08.010_bib0005","doi-asserted-by":"crossref","first-page":"877","DOI":"10.2217\/fmb.11.73","article-title":"Ocular herpes simplex virus: how are latency, reactivation, recurrent disease and therapy interrelated?","volume":"6","author":"Al-Dujaili","year":"2011","journal-title":"Future Microbiol."},{"issue":"1","key":"10.1016\/j.virusres.2015.08.010_bib0010","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1053\/jfms.2001.0110","article-title":"Ocular manifestations of feline herpesvirus","volume":"3","author":"Andrew","year":"2001","journal-title":"J. Feline Med. Surg."},{"issue":"3","key":"10.1016\/j.virusres.2015.08.010_bib0015","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1053\/jfms.2000.0084","article-title":"A study of feline upper respiratory tract disease with reference to prevalence and risk factors for infection with feline calicivirus and feline herpesvirus","volume":"2","author":"Binns","year":"2000","journal-title":"J. Feline Med. Surg."},{"issue":"1\u20132","key":"10.1016\/j.virusres.2015.08.010_bib0020","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0378-1135(01)00492-8","article-title":"Evolution of the herpesviruses","volume":"86","author":"Davison","year":"2002","journal-title":"Vet. Microbiol."},{"issue":"2\u20133","key":"10.1016\/j.virusres.2015.08.010_bib0025","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.antiviral.2006.03.018","article-title":"Herpesvirus latency and therapy\u2014from a veterinary perspective","volume":"71","author":"Field","year":"2006","journal-title":"Antiviral Res."},{"issue":"2","key":"10.1016\/j.virusres.2015.08.010_bib0030","doi-asserted-by":"crossref","first-page":"470","DOI":"10.7589\/0090-3558-42.2.470","article-title":"First evidence of feline herpesvirus, calicivirus, parvovirus, and Ehrlichia exposure in Brazilian free-ranging felids","volume":"42","author":"Filoni","year":"2006","journal-title":"J. Wildl. Dis."},{"issue":"1\u20132","key":"10.1016\/j.virusres.2015.08.010_bib0035","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0378-1135(99)00092-9","article-title":"Herpesviruses of carnivores","volume":"69","author":"Gaskell","year":"1999","journal-title":"Vet. Microbiol."},{"issue":"2","key":"10.1016\/j.virusres.2015.08.010_bib0040","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1051\/vetres:2006063","article-title":"Feline herpesvirus","volume":"38","author":"Gaskell","year":"2007","journal-title":"Vet. Res."},{"issue":"7","key":"10.1016\/j.virusres.2015.08.010_bib0045","doi-asserted-by":"crossref","first-page":"e22160","DOI":"10.1371\/journal.pone.0022160","article-title":"Herpes simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa","volume":"6","author":"Glorieux","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.virusres.2015.08.010_bib0050","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/1297-9716-42-58","article-title":"A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosa","volume":"42","author":"Glorieux","year":"2011","journal-title":"Vet. Res."},{"issue":"3","key":"10.1016\/j.virusres.2015.08.010_bib0055","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1463-5224.2008.00615.x","article-title":"Feline early life ocular disease","volume":"11","author":"Jacobi","year":"2008","journal-title":"Vet. Ophthalmol."},{"issue":"7","key":"10.1016\/j.virusres.2015.08.010_bib0060","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1136\/bjo.76.7.412","article-title":"Non-traumatic acquisition of herpes simplex virus infection through the eye","volume":"76","author":"Kaye","year":"1992","journal-title":"Br. J. Ophthalmol."},{"issue":"1\u20132","key":"10.1016\/j.virusres.2015.08.010_bib0065","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jviromet.2006.07.010","article-title":"Tracheal organ cultures as a useful tool to study Felid herpesvirus 1 infection in respiratory epithelium","volume":"138","author":"Leeming","year":"2006","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.virusres.2015.08.010_bib0070","doi-asserted-by":"crossref","first-page":"495830","DOI":"10.5402\/2012\/495830","article-title":"Felid herpesvirus type 1 infection in cats: a natural host model for alphaherpesvirus pathogenesis","volume":"2012","author":"Maes","year":"2012","journal-title":"ISRN Vet. Sci."},{"issue":"2","key":"10.1016\/j.virusres.2015.08.010_bib0075","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1053\/j.ctsap.2004.12.013","article-title":"Update on pathogenesis, diagnosis, and treatment of feline herpesvirus type 1","volume":"20","author":"Maggs","year":"2005","journal-title":"Clin. Tech. Small Anim. Pract."},{"issue":"6","key":"10.1016\/j.virusres.2015.08.010_bib0080","first-page":"656","article-title":"The basement membrane in pathology","volume":"48","author":"Martinez-Hernandez","year":"1983","journal-title":"Lab. Invest."},{"issue":"8","key":"10.1016\/j.virusres.2015.08.010_bib0085","first-page":"1758","article-title":"Experimental ocular herpesvirus infection in the cat. Sites of virus replication, clinical features and effects of corticosteroid administration","volume":"30","author":"Nasisse","year":"1989","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"5","key":"10.1016\/j.virusres.2015.08.010_bib0090","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1076\/ceyr.16.5.405.7044","article-title":"A histochemical study of the distribution of dextran 500 in human corneas during organ culture","volume":"16","author":"Redbrake","year":"1997","journal-title":"Curr. Eye Res."},{"issue":"2","key":"10.1016\/j.virusres.2015.08.010_bib0095","doi-asserted-by":"crossref","first-page":"217","DOI":"10.2460\/ajvr.2005.66.217","article-title":"Effects of cidofovir on cell death and replication of feline herpesvirus-1 in cultured feline corneal epithelial cells","volume":"66","author":"Sandmeyer","year":"2005","journal-title":"Am. J. Vet. Res."},{"issue":"3","key":"10.1016\/j.virusres.2015.08.010_bib0100","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.tim.2012.01.001","article-title":"Diverse microbial interactions with the basement membrane barrier","volume":"20","author":"Steukers","year":"2012","journal-title":"Trends Microbiol."},{"issue":"1","key":"10.1016\/j.virusres.2015.08.010_bib0105","doi-asserted-by":"crossref","first-page":"E43","DOI":"10.1093\/ilar.53.1.43","article-title":"Kinetics of BoHV-1 dissemination in an in vitro culture of bovine upper respiratory tract mucosa explants","volume":"53","author":"Steukers","year":"2012","journal-title":"ILAR J."},{"issue":"2","key":"10.1016\/j.virusres.2015.08.010_bib0110","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.tvjl.2013.11.018","article-title":"Ocular manifestations of feline viral diseases","volume":"201","author":"Stiles","year":"2014","journal-title":"Vet. J."},{"issue":"7","key":"10.1016\/j.virusres.2015.08.010_bib0115","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.jfms.2009.05.003","article-title":"Feline herpesvirus infection. ABCD guidelines on prevention and management","volume":"11","author":"Thiry","year":"2009","journal-title":"J. Feline Med. Surg."},{"key":"10.1016\/j.virusres.2015.08.010_bib0120","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1186\/1746-6148-9-185","article-title":"Ocular and neural distribution of feline herpesvirus-1 during active and latent experimental infection in cats","volume":"9","author":"Townsend","year":"2013","journal-title":"BMC Vet. Res."},{"issue":"6","key":"10.1016\/j.virusres.2015.08.010_bib0125","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1001\/archopht.1983.01040010961023","article-title":"Ocular infection with herpes simplex virus in nonimmune and immune mice","volume":"101","author":"Tullo","year":"1983","journal-title":"Arch. Ophthalmol."},{"issue":"pt 8","key":"10.1016\/j.virusres.2015.08.010_bib0130","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1099\/vir.0.019257-0","article-title":"Replication kinetics of neurovirulent versus non-neurovirulent equine herpesvirus type 1 strains in equine nasal mucosal explants","volume":"91","author":"Vandekerckhove","year":"2010","journal-title":"J. Gen. Virol."},{"issue":"1\u20132","key":"10.1016\/j.virusres.2015.08.010_bib0135","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.vetmic.2011.03.038","article-title":"Equine alphaherpesviruses (EHV-1 and EHV-4) differ in their efficiency to infect mononuclear cells during early steps of infection in nasal mucosal explants","volume":"152","author":"Vandekerckhove","year":"2011","journal-title":"Vet. Microbiol."},{"issue":"12","key":"10.1016\/j.virusres.2015.08.010_bib0140","doi-asserted-by":"crossref","first-page":"e51054","DOI":"10.1371\/journal.pone.0051054","article-title":"Immobilization of pseudorabies virus in porcine tracheal respiratory mucus revealed by single particle tracking","volume":"7","author":"Yang","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.virusres.2015.08.010_bib0145","first-page":"120","article-title":"Increased severity of HSV-1 keratitis and mortality in mice lacking the 2-5A-dependent RNase L gene","volume":"42","author":"Zheng","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."}],"container-title":["Virus Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170215300423?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170215300423?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T09:53:56Z","timestamp":1584006836000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168170215300423"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":29,"alternative-id":["S0168170215300423"],"URL":"https:\/\/doi.org\/10.1016\/j.virusres.2015.08.010","relation":{},"ISSN":["0168-1702"],"issn-type":[{"value":"0168-1702","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ex vivo modeling of feline herpesvirus replication in ocular and respiratory mucosae, the primary targets of infection","name":"articletitle","label":"Article Title"},{"value":"Virus Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virusres.2015.08.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}