{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T15:43:32Z","timestamp":1789055012225,"version":"build-2803163510"},"reference-count":205,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virus Research"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.virusres.2020.198108","type":"journal-article","created":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T11:27:11Z","timestamp":1596626831000},"page":"198108","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":101,"special_numbering":"C","title":["Melatonin potentials against viral infections including COVID-19: Current evidence and new findings"],"prefix":"10.1016","volume":"287","author":[{"given":"Kobra","family":"Bahrampour Juybari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Hossein","family":"Pourhanifeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azam","family":"Hosseinzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Hemati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed","family":"Mehrzadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.9734\/jammr\/2020\/v32i430393","article-title":"The Coronavirus disease 2019 (COVID-19): a review","volume":"32","author":"Ahmed","year":"2020","journal-title":"J. Adv. Med. Med. Res."},{"issue":"7","key":"10.1016\/j.virusres.2020.198108_bib0010","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1002\/jnr.24220","article-title":"The neuroprotective role of melatonin in neurological disorders","volume":"96","author":"Alghamdi","year":"2018","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0015","series-title":"In press. Chap 4. bk: Frontiers in Clinical Drug Research-Central Nervous System","article-title":"Alpha 7 nicotinic receptor agonist modulatory interactions with melatonin: relevance not only to cognition, but to wider neuropsychiatric and immune inflammatory disorders","author":"Anderson","year":"2016"},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0020","doi-asserted-by":"crossref","first-page":"e2109","DOI":"10.1002\/rmv.2109","article-title":"Melatonin: roles in influenza, Covid\u201019, and other viral infections","volume":"30","author":"Anderson","year":"2020","journal-title":"Rev. Med. Virol."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0025","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/sj.emboj.7601974","article-title":"Protein quality control in the early secretory pathway","volume":"27","author":"Anelli","year":"2008","journal-title":"EMBO J."},{"issue":"2\u20133","key":"10.1016\/j.virusres.2020.198108_bib0030","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1007\/s001090100210","article-title":"Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research","volume":"79","author":"Bader","year":"2001","journal-title":"J. Mol. Med."},{"issue":"7","key":"10.1016\/j.virusres.2020.198108_bib0035","doi-asserted-by":"crossref","first-page":"3558","DOI":"10.1128\/JVI.02827-15","article-title":"Venezuelan equine encephalitis virus induces apoptosis through the unfolded protein response activation of EGR1","volume":"90","author":"Baer","year":"2016","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2020.198108_bib0040","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.biopha.2018.09.044","article-title":"Evaluating the protective effects of melatonin on di (2-ethylhexyl) phthalate-induced testicular injury in adult mice","volume":"108","author":"Bahrami","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0045","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/imm.12443","article-title":"Immune mechanisms linked to depression via oxidative stress and neuroprogression","volume":"144","author":"Bakunina","year":"2015","journal-title":"Immunology"},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0050","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/S0002-9378(15)31857-3","article-title":"Disseminated intravascular coagulation during the continuous infusion of endotoxin in rabbits: morphologic and physiologic studies","volume":"103","author":"Beller","year":"1969","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0055","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/BF01309858","article-title":"Protective effects of melatonin in mice infected with encephalitis viruses","volume":"140","author":"Ben-Nathan","year":"1995","journal-title":"Arch. Virol."},{"issue":"26","key":"10.1016\/j.virusres.2020.198108_bib0060","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1056\/NEJMra1208937","article-title":"Acute liver failure","volume":"369","author":"Bernal","year":"2013","journal-title":"N. Engl. J. Med."},{"issue":"1 Suppl","key":"10.1016\/j.virusres.2020.198108_bib0065","doi-asserted-by":"crossref","first-page":"S112","DOI":"10.1016\/j.jhep.2014.12.016","article-title":"Acute liver failure: a curable disease by 2024?","volume":"62","author":"Bernal","year":"2015","journal-title":"J. Hepatol."},{"issue":"5","key":"10.1016\/j.virusres.2020.198108_bib0070","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/rmv.1714","article-title":"Beneficial actions of melatonin in the management of viral infections: a new use for this \u201cmolecular handyman\u201d?","volume":"22","author":"Boga","year":"2012","journal-title":"Rev. Med. Virol."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0075","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.cyto.2011.08.037","article-title":"Melatonin and zinc treatment: distinctive modulation of cytokine production in chronic experimental Trypanosoma cruzi infection","volume":"56","author":"Braz\u00e3o","year":"2011","journal-title":"Cytokine"},{"key":"10.1016\/j.virusres.2020.198108_bib0080","doi-asserted-by":"crossref","first-page":"428","DOI":"10.3389\/fimmu.2014.00428","article-title":"The role of myeloid cell activation and arginine metabolism in the pathogenesis of virus-induced diseases","volume":"5","author":"Burrack","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.virusres.2020.198108_bib0085","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.jneuroim.2017.04.008","article-title":"Virus entry and replication in the brain precedes blood-brain barrier disruption during intranasal alphavirus infection","volume":"308","author":"Cain","year":"2017","journal-title":"J. Neuroimmunol."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0090","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.regpep.2004.02.001","article-title":"Differential regulation of central vasopressin receptors in transgenic rats with low brain angiotensinogen","volume":"119","author":"Campos","year":"2004","journal-title":"Regul. Pept."},{"key":"10.1016\/j.virusres.2020.198108_bib0095","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/521783","article-title":"The angiotensin-melatonin axis","volume":"2013","author":"Campos","year":"2013","journal-title":"Int. J. Hypertens."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0100","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1600-079X.2011.00910.x","article-title":"Melatonin modulation of intracellular signaling pathways in hepatocarcinoma HepG2 cell line: role of the MT1 receptor","volume":"51","author":"Carbajo\u2010Pescador","year":"2011","journal-title":"J. Pineal Res."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0105","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1159\/000446543","article-title":"Inflammaging, metabolic syndrome and melatonin: a call for treatment studies","volume":"104","author":"Cardinali","year":"2017","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.virusres.2020.198108_bib0110","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1749-6632.2000.tb05403.x","article-title":"Gene regulation by melatonin","volume":"917","author":"Carlberg","year":"2000","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0115","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1096\/fj.03-0694fje","article-title":"Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and\/or paracrine substance","volume":"18","author":"Carrillo-Vico","year":"2004","journal-title":"FASEB J."},{"issue":"5","key":"10.1016\/j.virusres.2020.198108_bib0120","first-page":"423","article-title":"The modulatory role of melatonin on immune responsiveness","volume":"7","author":"Carrillo-Vico","year":"2006","journal-title":"Curr. Opin. Investig. Drugs"},{"issue":"7","key":"10.1016\/j.virusres.2020.198108_bib0125","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.it.2009.05.002","article-title":"Vaccination in the elderly: an immunological perspective","volume":"30","author":"Chen","year":"2009","journal-title":"Trends Immunol."},{"issue":"15","key":"10.1016\/j.virusres.2020.198108_bib0130","doi-asserted-by":"crossref","first-page":"7703","DOI":"10.1128\/JVI.02560-09","article-title":"Upregulation of the chemokine (CC motif) ligand 2 via a severe acute respiratory syndrome coronavirus spike-ACE2 signaling pathway","volume":"84","author":"Chen","year":"2010","journal-title":"J. Virol."},{"issue":"5","key":"10.1016\/j.virusres.2020.198108_bib0135","first-page":"439","article-title":"Melatonin augments apoptotic adipose-derived mesenchymal stem cell treatment against sepsis-induced acute lung injury","volume":"6","author":"Chen","year":"2014","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.eng.2020.02.006","article-title":"Clinical study of mesenchymal stem cell treating acute respiratory distress syndrome induced by epidemic Influenza A (H7N9) infection, a hint for COVID-19 treatment","author":"Chen","year":"2020","journal-title":"Engineering."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0145","first-page":"193","article-title":"Melatonin prevents the decreased activity of antioxidant enzymes and activates nuclear erythroid 2\u2010related factor 2 signaling in an animal model of fulminant hepatic failure of viral origin","volume":"49","author":"Crespo","year":"2010","journal-title":"J. Pineal Res."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0150","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/jpi.12335","article-title":"Melatonin inhibits the sphingosine kinase 1\/sphingosine\u20101\u2010phosphate signaling pathway in rabbits with fulminant hepatitis of viral origin","volume":"61","author":"Crespo","year":"2016","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0155","doi-asserted-by":"crossref","DOI":"10.1111\/jcmm.15398","article-title":"Melatonin modulates mitophagy, innate immunity and circadian clocks in a model of viral\u2010induced fulminant hepatic failure","author":"Crespo","year":"2020","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.virusres.2020.198108_bib0160","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.biopha.2017.11.007","article-title":"The potential use of melatonin to treat protozoan parasitic infections: a review","volume":"97","author":"Daryani","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0165","doi-asserted-by":"crossref","first-page":"194","DOI":"10.4269\/ajtmh.1985.34.194","article-title":"The systemic pathology of Venezuelan equine encephalitis virus infection in humans","volume":"34","author":"de la Monte","year":"1985","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"9","key":"10.1016\/j.virusres.2020.198108_bib0170","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/j.bbamcr.2008.12.011","article-title":"Autophagy in the cardiovascular system","volume":"1793","author":"De Meyer","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.virusres.2020.198108_bib0175","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.lfs.2017.12.001","article-title":"Diabetic retinopathy pathogenesis and the ameliorating effects of melatonin; involvement of autophagy, inflammation and oxidative stress","volume":"193","author":"Dehdashtian","year":"2018","journal-title":"Life Sci."},{"key":"10.1016\/j.virusres.2020.198108_bib0180","doi-asserted-by":"crossref","DOI":"10.1002\/dmrr.3336","article-title":"Therapeutic application of nutraceuticals in diabetic nephropathy: current evidence and future implications","author":"Dehdashtian","year":"2020","journal-title":"Diabetes\/Metabol. Res. Rev."},{"issue":"5","key":"10.1016\/j.virusres.2020.198108_bib0185","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.arcmed.2020.04.019","article-title":"Oxidative stress as key player in severe acute respiratory syndrome coronavirus (SARS-CoV) infection","volume":"51","author":"Delgado-Roche","year":"2020","journal-title":"Arch. Med. Res."},{"issue":"11","key":"10.1016\/j.virusres.2020.198108_bib0190","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1517\/13543784.2012.716037","article-title":"Melatonin in cardiovascular disease","volume":"21","author":"Dominguez-Rodriguez","year":"2012","journal-title":"Expert Opin. Investig. Drugs"},{"issue":"12","key":"10.1016\/j.virusres.2020.198108_bib0195","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.1096\/fasebj.2.12.2842214","article-title":"Pharmacology and function of melatonin receptors","volume":"2","author":"Dubocovich","year":"1988","journal-title":"FASEB J."},{"key":"10.1016\/j.virusres.2020.198108_bib0200","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.phrs.2016.03.018","article-title":"ACE inhibition, ACE2 and angiotensin-(1-7) axis in kidney and cardiac inflammation and fibrosis","volume":"107","author":"e Silva","year":"2016","journal-title":"Pharmacol. Res."},{"issue":"17","key":"10.1016\/j.virusres.2020.198108_bib0205","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1056\/NEJMoa043951","article-title":"Respiratory syncytial virus infection in elderly and high-risk adults","volume":"352","author":"Falsey","year":"2005","journal-title":"N. Engl. J. Med."},{"issue":"12","key":"10.1016\/j.virusres.2020.198108_bib0210","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1093\/infdis\/jit839","article-title":"Respiratory syncytial virus and other respiratory viral infections in older adults with moderate to severe influenza-like illness","volume":"209","author":"Falsey","year":"2014","journal-title":"Journal of Infectious Disease"},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0215","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1007\/s12094-018-1934-0","article-title":"Melatonin as an adjuvant in radiotherapy for radioprotection and radiosensitization","volume":"21","author":"Farhood","year":"2019","journal-title":"Clin. Transl. Oncol."},{"issue":"9","key":"10.1016\/j.virusres.2020.198108_bib0220","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1038\/s41395-018-0160-2","article-title":"Acute liver failure of indeterminate etiology: a comprehensive systematic approach by an expert committee to establish causality","volume":"113","author":"Ganger","year":"2018","journal-title":"Am. J. Gastroenterol."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0225","doi-asserted-by":"crossref","first-page":"574","DOI":"10.4049\/jimmunol.159.2.574","article-title":"Melatonin enhances IL-2, IL-6, and IFN-gamma production by human circulating CD4+ cells: a possible nuclear receptor-mediated mechanism involving T helper type 1 lymphocytes and monocytes","volume":"159","author":"Garcia-Maurino","year":"1997","journal-title":"J. Immunol."},{"issue":"21","key":"10.1016\/j.virusres.2020.198108_bib0230","doi-asserted-by":"crossref","first-page":"10634","DOI":"10.1128\/JVI.01323-08","article-title":"Eastern and venezuelan equine encephalitis viruses differ in their ability to infect dendritic cells and macrophages: impact of altered cell tropism on pathogenesis","volume":"82","author":"Gardner","year":"2008","journal-title":"J. Virol."},{"issue":"9400","key":"10.1016\/j.virusres.2020.198108_bib0235","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1016\/S0140-6736(03)15012-X","article-title":"Treatment of ebola virus infection with a recombinant inhibitor of factor VIIa\/tissue factor: a study in rhesus monkeys","volume":"362","author":"Geisbert","year":"2003","journal-title":"Lancet (London, England)"},{"issue":"21","key":"10.1016\/j.virusres.2020.198108_bib0240","doi-asserted-by":"crossref","first-page":"e831","DOI":"10.1097\/MD.0000000000000831","article-title":"Respiratory syncytial virus bronchiolitis in children up to 5 years of age in Spain: epidemiology and comorbidities: an observational study","volume":"94","author":"Gil-Prieto","year":"2015","journal-title":"Medicine"},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0245","doi-asserted-by":"crossref","first-page":"22","DOI":"10.2174\/1574888X13666180913123424","article-title":"The clinical trials of mesenchymal stem cell therapy in skin diseases: an update and concise review","volume":"14","author":"Golchin","year":"2019","journal-title":"Curr. Stem Cell Res. Ther."},{"key":"10.1016\/j.virusres.2020.198108_bib0250","first-page":"1","article-title":"Mesenchymal stem cell therapy for COVID-19: present or future","author":"Golchin","year":"2020","journal-title":"Stem Cell Rev. Rep."},{"key":"10.1016\/j.virusres.2020.198108_bib0255","article-title":"Correlation analysis between disease severity and inflammation-related parameters in patients with COVID-19 pneumonia","author":"Gong","year":"2020","journal-title":"MedRxiv"},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0260","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s00395-009-0011-9","article-title":"Cardioprotection requires taking out the trash","volume":"104","author":"Gottlieb","year":"2009","journal-title":"Basic Res. Cardiol."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0265","doi-asserted-by":"crossref","first-page":"467","DOI":"10.2174\/1568026616666160824120338","article-title":"Melatonin and respiratory diseases: a review","volume":"17","author":"Habtemariam","year":"2017","journal-title":"Curr. Top. Med. Chem."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0270","doi-asserted-by":"crossref","DOI":"10.1111\/jpi.12525","article-title":"Melatonin and inflammation-Story of a double-edged blade","volume":"65","author":"Hardeland","year":"2018","journal-title":"J. Pineal Res."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0275","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1600-079X.1996.tb00245.x","article-title":"Melatonin rhythms and pineal structure in a tropical bat, Anoura geoffroyi, that does not use photoperiod to regulate seasonal reproduction","volume":"20","author":"Heideman","year":"1996","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0280","article-title":"Melatonin and morphine: potential beneficial effects of co\u2010use","author":"Hemati","year":"2020","journal-title":"Fundam. Clin. Pharmacol."},{"issue":"5","key":"10.1016\/j.virusres.2020.198108_bib0285","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1399-3038.2005.00298.x","article-title":"Hospitalization for RSV bronchiolitis before 12 months of age and subsequent asthma, atopy and wheeze: a longitudinal birth cohort study","volume":"16","author":"Henderson","year":"2005","journal-title":"Pediatr. Allergy Immunol."},{"issue":"6","key":"10.1016\/j.virusres.2020.198108_bib0290","first-page":"2234","article-title":"Biological effects of melatonin on human adipose\u2011derived mesenchymal stem cells","volume":"44","author":"Heo","year":"2019","journal-title":"Int. J. Mol. Med."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0295","doi-asserted-by":"crossref","first-page":"R183","DOI":"10.1530\/ERC-15-0030","article-title":"Melatonin: an inhibitor of breast cancer","volume":"22","author":"Hill","year":"2015","journal-title":"Endocr. Relat. Cancer"},{"issue":"24","key":"10.1016\/j.virusres.2020.198108_bib0300","doi-asserted-by":"crossref","first-page":"13795","DOI":"10.1128\/JVI.02422-13","article-title":"The cytoprotective enzyme heme oxygenase-1 suppresses ebola virus replication","volume":"87","author":"Hill-Batorski","year":"2013","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0305","article-title":"Proceedings: the effect of melatonin on pinealectomy-induced hypertension in the rat","volume":"56","author":"Holmes","year":"1976","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.virusres.2020.198108_bib0310","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1056\/NEJMoa2001191","article-title":"First case of 2019 novel coronavirus in the United States","volume":"382","author":"Holshue","year":"2020","journal-title":"N. Engl. J. Med."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0315","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/jpi.12362","article-title":"Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin","volume":"61","author":"Hosseinzadeh","year":"2016","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0320","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.lfs.2018.03.032","article-title":"Idiopathic pulmonary fibrosis (IPF) signaling pathways and protective roles of melatonin","volume":"201","author":"Hosseinzadeh","year":"2018","journal-title":"Life Sci."},{"issue":"12","key":"10.1016\/j.virusres.2020.198108_bib0325","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1080\/14728222.2018.1541318","article-title":"Oxidative\/nitrosative stress, autophagy and apoptosis as therapeutic targets of melatonin in idiopathic pulmonary fibrosis","volume":"22","author":"Hosseinzadeh","year":"2018","journal-title":"Expert Opin. Ther. Targets"},{"issue":"11","key":"10.1016\/j.virusres.2020.198108_bib0330","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.2174\/1389450120666190319162147","article-title":"Molecular aspects of melatonin treatment in tinnitus: a review","volume":"20","author":"Hosseinzadeh","year":"2019","journal-title":"Curr. Drug Targets"},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0335","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s13287-018-1114-8","article-title":"Melatonin plays critical role in mesenchymal stem cell-based regenerative medicine in vitro and in vivo","volume":"10","author":"Hu","year":"2019","journal-title":"Stem Cell Res. Ther."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0340","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/jmv.20255","article-title":"An interferon\u2010\u03b3\u2010related cytokine storm in SARS patients","volume":"75","author":"Huang","year":"2005","journal-title":"J. Med. Virol."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0345","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/j.1600-079X.2008.00560.x","article-title":"Melatonin decreases TLR3-mediated inflammatory factor expression via inhibition of NF-kappa B activation in respiratory syncytial virus-infected RAW264.7 macrophages","volume":"45","author":"Huang","year":"2008","journal-title":"J. Pineal Res."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0350","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1600-079X.2009.00733.x","article-title":"Inhibitory effect of melatonin on lung oxidative stress induced by respiratory syncytial virus infection in mice","volume":"48","author":"Huang","year":"2010","journal-title":"J. Pineal Res."},{"issue":"10223","key":"10.1016\/j.virusres.2020.198108_bib0355","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet"},{"issue":"10223","key":"10.1016\/j.virusres.2020.198108_bib0360","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.virusres.2020.198108_bib0365","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/678164","article-title":"The bidirectional relationship between sleep and immunity against infections","volume":"2015","author":"Ibarra-Coronado","year":"2015","journal-title":"J. Immunol. Res."},{"issue":"6","key":"10.1016\/j.virusres.2020.198108_bib0370","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.3390\/nu12061562","article-title":"Strengthening the immune system and reducing inflammation and oxidative stress through diet and nutrition: considerations during the COVID-19 crisis","volume":"12","author":"Iddir","year":"2020","journal-title":"Nutrients"},{"issue":"16","key":"10.1016\/j.virusres.2020.198108_bib0375","doi-asserted-by":"crossref","first-page":"3230","DOI":"10.1111\/bph.13898","article-title":"Melatonin in regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis: involvement of circadian clock genes","volume":"175","author":"Jahanban-Esfahlan","year":"2018","journal-title":"Br. J. Pharmacol."},{"issue":"20","key":"10.1016\/j.virusres.2020.198108_bib0380","doi-asserted-by":"crossref","first-page":"10605","DOI":"10.1128\/JVI.01090-09","article-title":"Respiratory syncytial virus infection induces a reactive oxygen species-MSK1-phospho-Ser-276 RelA pathway required for cytokine expression","volume":"83","author":"Jamaluddin","year":"2009","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2020.198108_bib0385","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.12688\/f1000research.9637.1","article-title":"Respiratory syncytial virus infection: an innate perspective","volume":"5","author":"Johansson","year":"2016","journal-title":"F1000Research"},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0390","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2019.100765","article-title":"Ebola hemorrhagic shock syndrome-on-a-Chip","volume":"23","author":"Junaid","year":"2020","journal-title":"iScience"},{"issue":"28","key":"10.1016\/j.virusres.2020.198108_bib0395","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.2174\/1381612825666190829151314","article-title":"Melatonin as a modulator of degenerative and regenerative signaling pathways in injured Retinal Ganglion Cells","volume":"25","author":"Juybari","year":"2019","journal-title":"Curr. Pharm. Des."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0400","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1600-079X.2010.00837.x","article-title":"Human amniotic epithelial cells express melatonin receptor MT1, but not melatonin receptor MT2: a new perspective to neuroprotection","volume":"50","author":"Kaneko","year":"2011","journal-title":"J. Pineal Res."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0405","first-page":"105","article-title":"Melatonin in type 2 diabetes mellitus and obesity. Nature reviews","volume":"15","author":"Karamitri","year":"2019","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0410","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/j.1748-1716.1975.tb05878.x","article-title":"Plasma renin activity and in vitro synthesis of aldosterone by the adrenal glands of rats with spontaneous, renal, or pinealectomy\u2010induced hypertension","volume":"94","author":"Karppanen","year":"1975","journal-title":"Acta Physiol. Scand."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0415","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/j.1600-079X.1999.tb00578.x","article-title":"Effects of melatonin on macrophages\/microglia in postnatal rat brain","volume":"26","author":"Kaur","year":"1999","journal-title":"J. Pineal Res."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0420","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1080\/21505594.2018.1509668","article-title":"Direct and indirect pro-inflammatory cytokine response resulting from TC-83 infection of glial cells","volume":"9","author":"Keck","year":"2018","journal-title":"Virulence"},{"issue":"5","key":"10.1016\/j.virusres.2020.198108_bib0425","first-page":"659","article-title":"Melatonin, advanced oxidation protein products and total antioxidant capacity as seminal parameters of prooxidant-antioxidant balance and their connection with expression of metalloproteinases in context of male fertility","volume":"68","author":"Kratz","year":"2017","journal-title":"J. Physiol. Pharmacol."},{"issue":"13","key":"10.1016\/j.virusres.2020.198108_bib0430","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1161\/CIRCULATIONAHA.105.548156","article-title":"Viral persistence in the myocardium is associated with progressive cardiac dysfunction","volume":"112","author":"Kuhl","year":"2005","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0435","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/jcp.10167","article-title":"Emerging functions of p21\u2010activated kinases in human cancer cells","volume":"193","author":"Kumar","year":"2002","journal-title":"J. Cell. Physiol."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0440","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1111\/j.1600-079X.2012.00995.x","article-title":"Melatonin attenuates inflammation and promotes regeneration in rabbits with fulminant hepatitis of viral origin","volume":"53","author":"Laliena","year":"2012","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0445","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jhep.2017.08.034","article-title":"Type A viral hepatitis: a summary and update on the molecular virology, epidemiology, pathogenesis and prevention","volume":"68","author":"Lemon","year":"2017","journal-title":"J. Hepatol."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0450","doi-asserted-by":"crossref","first-page":"216","DOI":"10.14336\/AD.2020.0228","article-title":"Transplantation of ACE2-mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia","volume":"11","author":"Leng","year":"2020","journal-title":"Aging Dis."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0455","first-page":"159","article-title":"Eating oneself and uninvited guests: autophagy-related pathways in cellular defense","volume":"120","author":"Levine","year":"2005","journal-title":"Cell"},{"issue":"6","key":"10.1016\/j.virusres.2020.198108_bib0460","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1002\/jmv.25728","article-title":"The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients","volume":"92","author":"Li","year":"2020","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.virusres.2020.198108_bib0465","first-page":"v1","article-title":"Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord mesenchymal stem cells","volume":"2","author":"Liang","year":"2020","journal-title":"ChinaXiv"},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0470","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.bbrc.2017.01.116","article-title":"Inhibition of Drp1 attenuates mitochondrial damage and myocardial injury in Coxsackievirus B3 induced myocarditis","volume":"484","author":"Lin","year":"2017","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0475","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1074\/jbc.M307251200","article-title":"Reactive oxygen species mediate virus-induced STAT activation: role of tyrosine phosphatases","volume":"279","author":"Liu","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0480","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/jpi.12045","article-title":"Melatonin mediates protective effects on inflammatory response induced by interleukin\u20101 beta in human mesenchymal stem cells","volume":"55","author":"Liu","year":"2013","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0485","doi-asserted-by":"crossref","first-page":"791","DOI":"10.3389\/fendo.2019.00791","article-title":"Melatonin target proteins: too many or not enough?","volume":"10","author":"Liu","year":"2019","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0490","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1007\/s11427-020-1643-8","article-title":"Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury","volume":"63","author":"Liu","year":"2020","journal-title":"Sci. China Life Sci."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0495","doi-asserted-by":"crossref","DOI":"10.1111\/jpi.12490","article-title":"Melatonin and cardioprotection against ischaemia\/reperfusion injury: what\u2019s new? A review","volume":"65","author":"Lochner","year":"2018","journal-title":"J. Pineal Res."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0500","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1002\/jmv.25678","article-title":"Outbreak of pneumonia of unknown etiology in Wuhan China: the mystery and the miracle","volume":"92","author":"Lu","year":"2020","journal-title":"J. Med. Virol."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0505","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1161\/ATVBAHA.119.313757","article-title":"PTEN (phosphatase and tensin homolog) protects against Ang II (Angiotensin II)-induced pathological vascular fibrosis and remodeling\u2014brief report. Arteriosclerosis","volume":"40","author":"Lu","year":"2020","journal-title":"Thromb. Vasc. Biol."},{"issue":"10","key":"10.1016\/j.virusres.2020.198108_bib0510","doi-asserted-by":"crossref","first-page":"3603","DOI":"10.1096\/fj.10-154450","article-title":"Melatonin signaling and cell protection function","volume":"24","author":"Luchetti","year":"2010","journal-title":"FASEB J."},{"issue":"25","key":"10.1016\/j.virusres.2020.198108_bib0515","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1056\/NEJMoa1409838","article-title":"Clinical care of two patients with Ebola virus disease in the United States","volume":"371","author":"Lyon","year":"2014","journal-title":"N. Engl. J. Med."},{"issue":"0","key":"10.1016\/j.virusres.2020.198108_bib0520","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.5604\/17322693.1221001","article-title":"Immunoregulatory action of melatonin. The mechanism of action and the effect on inflammatory cells","volume":"70","author":"Ma\u0144ka","year":"2016","journal-title":"Postepy Hig. Med. Dosw. Online (Online)"},{"issue":"6","key":"10.1016\/j.virusres.2020.198108_bib0525","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1001\/jamaneurol.2020.1127","article-title":"Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China","volume":"77","author":"Mao","year":"2020","journal-title":"JAMA Neurology"},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0530","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.pharmthera.2010.02.009","article-title":"Is modulation of nicotinic acetylcholine receptors by melatonin relevant for therapy with cholinergic drugs?","volume":"126","author":"Markus","year":"2010","journal-title":"Pharmacol. Ther."},{"issue":"5","key":"10.1016\/j.virusres.2020.198108_bib0535","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1002\/ptr.5054","article-title":"Herbal therapeutics that block the oncogenic kinase PAK1: a practical approach towards PAK1\u2010dependent diseases and longevity","volume":"28","author":"Maruta","year":"2014","journal-title":"Phytother. Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0540","doi-asserted-by":"crossref","DOI":"10.1016\/j.medidd.2020.100039","article-title":"PAK1-blockers: potential therapeutics against COVID-19","author":"Maruta","year":"2020","journal-title":"Med. Drug Discov."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0545","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1139\/cjpp-2015-0277","article-title":"Melatonin synergistically enhances protective effect of atorvastatin against gentamicin-induced nephrotoxicity in rat kidney","volume":"94","author":"Mehrzadi","year":"2016","journal-title":"Can. J. Physiol. Pharmacol."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0550","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1080\/14728222.2020.1737015","article-title":"Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment","volume":"24","author":"Mehrzadi","year":"2020","journal-title":"Expert Opin. Ther. Targets"},{"issue":"20","key":"10.1016\/j.virusres.2020.198108_bib0555","first-page":"19","article-title":"Correspondence COVID-19: consider cytokine storm syndromes and","volume":"6736","author":"Mehta","year":"2020","journal-title":"Lancet"},{"issue":"10229","key":"10.1016\/j.virusres.2020.198108_bib0560","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S0140-6736(20)30628-0","article-title":"COVID-19: consider cytokine storm syndromes and immunosuppression","volume":"395","author":"Mehta","year":"2020","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.virusres.2020.198108_bib0565","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1111\/liv.14458","article-title":"The emergency department as a setting-specific opportunity for population-based hepatitis C screening: an economic evaluation","volume":"40","author":"Mendlowitz","year":"2020","journal-title":"Liver Int."},{"key":"10.1016\/j.virusres.2020.198108_bib0570","first-page":"120","article-title":"Effects of hydrochlorothiazide, furosemide and ethacrynic acid on pinealectomy-induced hypertension in rats","volume":"49","author":"Meneuvonen","year":"1971","journal-title":"Ann. Med. Exp. Biol. Fenn."},{"key":"10.1016\/j.virusres.2020.198108_bib0575","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/s41577-020-0331-4","article-title":"Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages","volume":"20","author":"Merad","year":"2020","journal-title":"Nat. Rev. Immunol."},{"issue":"6","key":"10.1016\/j.virusres.2020.198108_bib0580","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/s41577-020-0331-4","article-title":"Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages","volume":"20","author":"Merad","year":"2020","journal-title":"Nat. Rev. Immunol."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0585","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.0959-9673.2006.00474.x","article-title":"The role of melatonin in immuno\u2010enhancement: potential application in cancer","volume":"87","author":"Miller","year":"2006","journal-title":"Int. J. Exp. Pathol."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0590","doi-asserted-by":"crossref","first-page":"386","DOI":"10.2353\/ajpath.2006.050137","article-title":"Autophagic cardiomyocyte death in cardiomyopathic hamsters and its prevention by granulocyte colony-stimulating factor","volume":"168","author":"Miyata","year":"2006","journal-title":"Am. J. Pathol."},{"issue":"3\u20134","key":"10.1016\/j.virusres.2020.198108_bib0595","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1177\/2040206616660851","article-title":"Melatonin decreases brain apoptosis, oxidative stress, and CD200 expression and increased survival rate in mice infected by Venezuelan equine encephalitis virus","volume":"24","author":"Montiel","year":"2015","journal-title":"Antivir. Chem. Chemother."},{"key":"10.1016\/j.virusres.2020.198108_bib0600","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2019.116960","article-title":"Boosting immune system against cancer by melatonin: a echanistic viewpoint","volume":"238","author":"Mortezaee","year":"2019","journal-title":"Life Sci."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0605","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1213\/ANE.0000000000000866","article-title":"Ebola virus disease: a review of its past and present","volume":"121","author":"Murray","year":"2015","journal-title":"Anesth. Analg."},{"issue":"12","key":"10.1016\/j.virusres.2020.198108_bib0610","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0052010","article-title":"NF-\u03baB drives the synthesis of melatonin in RAW 264.7 macrophages by inducing the transcription of the arylalkylamine-N-acetyltransferase (AA-NAT) gene","volume":"7","author":"Muxel","year":"2012","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0615","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.idc.2019.08.005","article-title":"Ebola virus disease: epidemiology, clinical features, management, and prevention","volume":"33","author":"Nicastri","year":"2019","journal-title":"Infect. Dis. Clin. North Am."},{"key":"10.1016\/j.virusres.2020.198108_bib0620","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.20061.1","article-title":"Chemokine regulation of inflammation during respiratory syncytial virus infection","volume":"8","author":"Nuriev","year":"2019","journal-title":"F1000Research"},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0625","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.bbrc.2016.04.105","article-title":"Anti-inflammatory activity of chloroquine and amodiaquine through p21-mediated suppression of T cell proliferation and Th1 cell differentiation","volume":"474","author":"Oh","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.virusres.2020.198108_bib0630","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3389\/fendo.2020.00085","article-title":"Melatonin and female reproduction: an expanding universe","volume":"11","author":"Olcese","year":"2020","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"10.1016\/j.virusres.2020.198108_bib0635","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1146\/annurev-immunol-051116-052206","article-title":"Protective and harmful immunity to RSV infection","volume":"35","author":"Openshaw","year":"2017","journal-title":"Annu. Rev. Immunol."},{"issue":"11","key":"10.1016\/j.virusres.2020.198108_bib0640","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.tcb.2017.05.007","article-title":"Apoptosis and necroptosis as host defense strategies to prevent viral infection","volume":"27","author":"Orzalli","year":"2017","journal-title":"Trends Cell Biol."},{"issue":"5","key":"10.1016\/j.virusres.2020.198108_bib0645","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/s10735-019-09836-w","article-title":"Inhibitory effect of melatonin on Mst1 ameliorates myocarditis through attenuating ER stress and mitochondrial dysfunction","volume":"50","author":"Ouyang","year":"2019","journal-title":"J. Mol. Histol."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0650","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1186\/s13104-018-3417-3","article-title":"Screening of melatonin, \u03b1-tocopherol, folic acid, acetyl-L-carnitine and resveratrol for anti-dengue 2 virus activity","volume":"11","author":"Paemanee","year":"2018","journal-title":"BMC Res. Notes"},{"issue":"12","key":"10.1016\/j.virusres.2020.198108_bib0655","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/S0022-2828(87)80528-X","article-title":"Short-term inhibition of cardiac cellular autophagy by isoproterenol","volume":"19","author":"Pfeifer","year":"1987","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0660","first-page":"369","article-title":"Impact of melatonin on immunity: a review","volume":"8","author":"Pohanka","year":"2013","journal-title":"Cent. Eur. J. Med."},{"key":"10.1016\/j.virusres.2020.198108_bib0665","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13098-020-00537-z","article-title":"Melatonin: new insights on its therapeutic properties in diabetic complications","volume":"12","author":"Pourhanifeh","year":"2020","journal-title":"Diabetol. Metab. Syndr."},{"key":"10.1016\/j.virusres.2020.198108_bib0670","article-title":"Dysregulation of immune response in patients with COVID-19 in Wuhan","author":"Qin","year":"2020","journal-title":"Clin. Infect. Dis.: China"},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0675","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1210\/edrv-12-2-151","article-title":"Pineal melatonin: cell biology of its synthesis and of its physiological interactions","volume":"12","author":"Reiter","year":"1991","journal-title":"Endocr. Rev."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0680","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/jpi.12360","article-title":"Melatonin as an antioxidant: under promises but over delivers","volume":"61","author":"Reiter","year":"2016","journal-title":"J. Pineal Res."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0685","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/jpi.12360","article-title":"Melatonin as an antioxidant: under promises but over delivers","volume":"61","author":"Reiter","year":"2016","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0690","doi-asserted-by":"crossref","first-page":"226","DOI":"10.3389\/fmed.2020.00226","article-title":"Therapeutic algorithm for use of melatonin in patients with COVID-19","volume":"7","author":"Reiter","year":"2020","journal-title":"Front. Med."},{"issue":"10231","key":"10.1016\/j.virusres.2020.198108_bib0695","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1016\/S0140-6736(20)30627-9","article-title":"COVID-19 and Italy: what next?","volume":"395","author":"Remuzzi","year":"2020","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0700","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1111\/cmi.12043","article-title":"Autophagy in antiviral innate immunity","volume":"15","author":"Richetta","year":"2013","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.virusres.2020.198108_bib0705","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1146\/annurev-virology-092917-043515","article-title":"Quis custodiet ipsos custodes? Regulation of cell-mediated immune responses following viral lung infections","volume":"5","author":"Rogers","year":"2018","journal-title":"Annu. Rev. Virol."},{"issue":"7","key":"10.1016\/j.virusres.2020.198108_bib0710","first-page":"519","article-title":"Signal integration in the endoplasmic reticulum unfolded protein response. Nature reviews","volume":"8","author":"Ron","year":"2007","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.virusres.2020.198108_bib0715","first-page":"1","article-title":"Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China","author":"Ruan","year":"2020","journal-title":"Intensive Care Med."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0720","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.immuni.2019.08.007","article-title":"Immunological lessons from respiratory syncytial virus vaccine development","volume":"51","author":"Ruckwardt","year":"2019","journal-title":"Immunity"},{"issue":"6","key":"10.1016\/j.virusres.2020.198108_bib0725","doi-asserted-by":"crossref","first-page":"3350","DOI":"10.1128\/JVI.79.6.3350-3357.2005","article-title":"Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression","volume":"79","author":"Rudd","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2020.198108_bib0730","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2020.106560","article-title":"Towards treatment planning of COVID-19: Rationale and hypothesis for the use of multiple immunosuppressive agents: anti-antibodies, immunoglobulins, and corticosteroids","volume":"84","author":"Saghazadeh","year":"2020","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0735","doi-asserted-by":"crossref","first-page":"87","DOI":"10.2214\/AJR.20.23034","article-title":"Coronavirus disease 2019 (COVID-19): a systematic review of imaging findings in 919 patients","volume":"215","author":"Salehi","year":"2020","journal-title":"Am. J. Roentgenol."},{"issue":"19","key":"10.1016\/j.virusres.2020.198108_bib0740","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.2174\/092986710791233689","article-title":"Clinical uses of melatonin: evaluation of human trials","volume":"17","author":"Sanchez-Barcelo","year":"2010","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.virusres.2020.198108_bib0745","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.3389\/fphar.2018.01384","article-title":"Melatonin ameliorates Coxsackievirus B3-induced myocarditis by regulating apoptosis and autophagy","volume":"9","author":"Sang","year":"2018","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0750","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/jpi.12124","article-title":"Melatonin modulates the autophagic response in acute liver failure induced by the rabbit hemorrhagic disease virus","volume":"56","author":"San\u2010Miguel","year":"2014","journal-title":"J. Pineal Res."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0755","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1600-079X.2008.00589.x","article-title":"Suppressive action of melatonin on the TH\u20102 immune response in rats infected with Trypanosoma cruzi","volume":"45","author":"Santello","year":"2008","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0760","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1146\/annurev-med-061813-012806","article-title":"Pathogenesis of macrophage activation syndrome and potential for cytokine-directed therapies","volume":"66","author":"Schulert","year":"2015","journal-title":"Annu. Rev. Med."},{"issue":"39","key":"10.1016\/j.virusres.2020.198108_bib0765","doi-asserted-by":"crossref","first-page":"4185","DOI":"10.2174\/1381612825666191113110225","article-title":"Melatonin: implications for ocular disease and therapeutic potential","volume":"25","author":"Scuderi","year":"2019","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.virusres.2020.198108_bib0770","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1186\/1471-2164-9-289","article-title":"Venezuelan equine encephalitis virus infection causes modulation of inflammatory and immune response genes in mouse brain","volume":"9","author":"Sharma","year":"2008","journal-title":"BMC Genomics"},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0775","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.tibs.2016.10.004","article-title":"Pyroptosis: gasdermin-mediated programmed necrotic cell death","volume":"42","author":"Shi","year":"2017","journal-title":"Trends Biochem. Sci."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0780","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41420-019-0181-7","article-title":"SARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes","volume":"5","author":"Shi","year":"2019","journal-title":"Cell Death Discov."},{"issue":"11","key":"10.1016\/j.virusres.2020.198108_bib0785","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1253\/jcj.65.965","article-title":"Autophagic degeneration as a possible mechanism of myocardial cell death in dilated cardiomyopathy","volume":"65","author":"Shimomura","year":"2001","journal-title":"Jpn. Circ. J."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0790","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1080\/08830185.2020.1756284","article-title":"Can melatonin reduce the severity of COVID-19 pandemic?","volume":"39","author":"Shneider","year":"2020","journal-title":"Int. Rev. Immunol."},{"issue":"12","key":"10.1016\/j.virusres.2020.198108_bib0795","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1136\/thx.2009.121582","article-title":"Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life","volume":"65","author":"Sigurs","year":"2010","journal-title":"Thorax"},{"key":"10.1016\/j.virusres.2020.198108_bib0800","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/1824-7288-39-61","article-title":"Melatonin: its possible role in the management of viral infections--a brief review","volume":"39","author":"Silvestri","year":"2013","journal-title":"Ital. J. Pediatr."},{"key":"10.1016\/j.virusres.2020.198108_bib0805","doi-asserted-by":"crossref","first-page":"616","DOI":"10.2741\/4125","article-title":"Experimental models of melatonin-deficient hypertension","volume":"18","author":"Simko","year":"2013","journal-title":"Front. Biosci."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0810","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3390\/molecules23020265","article-title":"Effect of melatonin on the renin-angiotensin-aldosterone system in L-NAME-induced hypertension","volume":"23","author":"Simko","year":"2018","journal-title":"Molecules"},{"issue":"33","key":"10.1016\/j.virusres.2020.198108_bib0815","doi-asserted-by":"crossref","first-page":"11876","DOI":"10.1073\/pnas.0505577102","article-title":"Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry","volume":"102","author":"Simmons","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0820","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.mce.2012.01.004","article-title":"Melatonin membrane receptors in peripheral tissues: distribution and functions","volume":"351","author":"Slominski","year":"2012","journal-title":"Mol. Cell. Endocrinol."},{"issue":"5","key":"10.1016\/j.virusres.2020.198108_bib0825","doi-asserted-by":"crossref","first-page":"H1084","DOI":"10.1152\/ajpheart.00217.2020","article-title":"COVID-19, ACE2, and the cardiovascular consequences","volume":"318","author":"South","year":"2020","journal-title":"Am. J. Physiol.-Heart Circul. Physiol."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0830","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1742-4933-2-17","article-title":"Melatonin, immune function and aging","volume":"2","author":"Srinivasan","year":"2005","journal-title":"Immun. Ageing"},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0835","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1177\/1534735408322846","article-title":"Therapeutic actions of melatonin in cancer: possible mechanisms","volume":"7","author":"Srinivasan","year":"2008","journal-title":"Integr. Cancer Ther."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0840","first-page":"207","article-title":"Breast cancer and circadian disruption from electric lighting in the modern world","volume":"64","author":"Stevens","year":"2014","journal-title":"CA Cancer J. Clin."},{"issue":"10201","key":"10.1016\/j.virusres.2020.198108_bib0845","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/S0140-6736(19)31894-X","article-title":"Acute liver failure","volume":"394","author":"Stravitz","year":"2019","journal-title":"Lancet (London, England)"},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0850","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/jpi.12186","article-title":"Ebola virus disease: potential use of melatonin as a treatment","volume":"57","author":"Tan","year":"2014","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0855","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/s41577-020-0311-8","article-title":"The trinity of COVID-19: immunity, inflammation and intervention","volume":"20","author":"Tay","year":"2020","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.virusres.2020.198108_bib0860","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s00101-020-00758-x","article-title":"Coronavirus disease 2019 \u201c(COVID-19): update f\u00fcr An\u00e4sthesisten und Intensivmediziner M\u00e4rz 2020","volume":"69","author":"Thomas-R\u00fcddel","year":"2020","journal-title":"Anaesthesist"},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0865","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.cbpa.2006.06.045","article-title":"V-H+-ATPase, Na+\/K+-ATPase and NHE2 immunoreactivity in the gill epithelium of the Pacific hagfish (Epatretus stoutii)","volume":"145","author":"Tresguerres","year":"2006","journal-title":"Comp. Biochem. Physiol., Part A Mol. Integr. Physiol."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0870","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/j.1600-079X.2010.00807.x","article-title":"Melatonin attenuates apoptotic liver damage in fulminant hepatic failure induced by the rabbit hemorrhagic disease virus","volume":"50","author":"Tu\u00f1\u00f3n","year":"2011","journal-title":"J. Pineal Res."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib0875","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/jpi.12063","article-title":"Melatonin treatment reduces endoplasmic reticulum stress and modulates the unfolded protein response in rabbits with lethal fulminant hepatitis of viral origin","volume":"55","author":"Tu\u00f1\u00f3n","year":"2013","journal-title":"J. Pineal Res."},{"issue":"1\u20133","key":"10.1016\/j.virusres.2020.198108_bib0880","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.ejphar.2010.04.041","article-title":"Effect of melatonin on neuroinflammation and acetylcholinesterase activity induced by LPS in rat brain","volume":"640","author":"Tyagi","year":"2010","journal-title":"Eur. J. Pharmacol."},{"issue":"11","key":"10.1016\/j.virusres.2020.198108_bib0885","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1007\/s11064-005-8634-1","article-title":"In vitro, melatonin treatment decreases nitric oxide levels in murine splenocytes cultured with the venezuelan equine encephalomyelitis virus","volume":"30","author":"Valero","year":"2005","journal-title":"Neurochem. Res."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0890","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1600-079X.2006.00381.x","article-title":"Melatonin decreases nitric oxide production and lipid peroxidation and increases interleukin-1 beta in the brain of mice infected by the Venezuelan equine encephalomyelitis virus","volume":"42","author":"Valero","year":"2007","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.virusres.2020.198108_bib0895","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.brainres.2015.06.034","article-title":"Melatonin, minocycline and ascorbic acid reduce oxidative stress and viral titers and increase survival rate in experimental Venezuelan equine encephalitis","volume":"1622","author":"Valero","year":"2015","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.virusres.2020.198108_bib0900","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1161\/CIRCRESAHA.114.304951","article-title":"Lack in treatment options for virus-induced inflammatory cardiomyopathy: can iPS-derived cardiomyocytes close the gap?","volume":"115","author":"Van Linthout","year":"2014","journal-title":"Circ. Res."},{"issue":"12","key":"10.1016\/j.virusres.2020.198108_bib0905","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1002\/ejhf.665","article-title":"Relevance of cardiac parvovirus B19 in myocarditis and dilated cardiomyopathy: review of the literature","volume":"18","author":"Verdonschot","year":"2016","journal-title":"Eur. J. Heart Fail."},{"issue":"7","key":"10.1016\/j.virusres.2020.198108_bib0910","first-page":"7277","article-title":"Calumenin relieves cardiac injury by inhibiting ERS-initiated apoptosis during viral myocarditis","volume":"10","author":"Wang","year":"2017","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0915","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1007\/s00380-016-0891-1","article-title":"Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways","volume":"32","author":"Wang","year":"2017","journal-title":"Heart Vessels"},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0920","first-page":"1867","article-title":"Oxidative stress modulates the expression of tolllike receptor 3 during respiratory syncytial virus infection in human lung epithelial A549 cells","volume":"18","author":"Wang","year":"2018","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.virusres.2020.198108_bib0925","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1146\/annurev.ento.49.061802.123422","article-title":"Venezuelan equine encephalitis","volume":"49","author":"Weaver","year":"2004","journal-title":"Annu. Rev. Entomol."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0930","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/MNH.0000000000000378","article-title":"Angiotensin-converting enzyme 2 and renal disease","volume":"27","author":"Williams","year":"2018","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"issue":"5","key":"10.1016\/j.virusres.2020.198108_bib0935","doi-asserted-by":"crossref","first-page":"3197","DOI":"10.1074\/jbc.C300520200","article-title":"A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2","volume":"279","author":"Wong","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"18","key":"10.1016\/j.virusres.2020.198108_bib0940","doi-asserted-by":"crossref","first-page":"9143","DOI":"10.1128\/JVI.00641-08","article-title":"Autophagosome supports coxsackievirus B3 replication in host cells","volume":"82","author":"Wong","year":"2008","journal-title":"J. Virol."},{"issue":"6483","key":"10.1016\/j.virusres.2020.198108_bib0945","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1126\/science.abb2507","article-title":"Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation","volume":"367","author":"Wrapp","year":"2020","journal-title":"Science"},{"issue":"13","key":"10.1016\/j.virusres.2020.198108_bib0950","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1001\/jama.2020.2648","article-title":"Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention","volume":"323","author":"Wu","year":"2020","journal-title":"Jama"},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0955","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1600-079X.2010.00825.x","article-title":"Melatonin inhibits microglial activation, reduces pro\u2010inflammatory cytokine levels, and rescues hippocampal neurons of adult rats with acute Klebsiella pneumoniae meningitis","volume":"50","author":"Wu","year":"2011","journal-title":"J. Pineal Res."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0960","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.bbrc.2003.11.054","article-title":"The SARS-CoV S glycoprotein: expression and functional characterization","volume":"312","author":"Xiao","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0965","first-page":"503","article-title":"Involvement of endoplasmic reticulum stress-associated apoptosis in a heart failure model induced by chronic myocardial ischemia","volume":"27","author":"Xin","year":"2011","journal-title":"Int. J. Mol. Med."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib0970","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1600-079X.2007.00445.x","article-title":"Maternally administered melatonin differentially regulates lipopolysaccharide\u2010induced proinflammatory and anti\u2010inflammatory cytokines in maternal serum, amniotic fluid, fetal liver, and fetal brain","volume":"43","author":"Xu","year":"2007","journal-title":"J. Pineal Res."},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib0975","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/S2213-2600(20)30076-X","article-title":"Pathological findings of COVID-19 associated with acute respiratory distress syndrome","volume":"8","author":"Xu","year":"2020","journal-title":"Lancet Respir. Med."},{"issue":"39","key":"10.1016\/j.virusres.2020.198108_bib0980","doi-asserted-by":"crossref","first-page":"13807","DOI":"10.1073\/pnas.0506843102","article-title":"Autophagy in chronically ischemic myocardium","volume":"102","author":"Yan","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.virusres.2020.198108_bib0985","doi-asserted-by":"crossref","first-page":"588","DOI":"10.3390\/ijms19020588","article-title":"New insights into the immune molecular regulation of the pathogenesis of acute respiratory distress syndrome","volume":"19","author":"Yang","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.virusres.2020.198108_bib0990","article-title":"Exuberant elevation of IP-10, MCP-3 and IL-1ra during SARS-CoV-2 infection is associated with disease severity and fatal outcome","author":"Yang","year":"2020","journal-title":"MedRxiv."},{"issue":"23","key":"10.1016\/j.virusres.2020.198108_bib0995","doi-asserted-by":"crossref","first-page":"11976","DOI":"10.1128\/JVI.01028-08","article-title":"Coxsackievirus B4 uses autophagy for replication after calpain activation in rat primary neurons","volume":"82","author":"Yoon","year":"2008","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.virusres.2020.198108_bib1000","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.phrs.2012.05.001","article-title":"Characterization of Angiotensin-(1\u20137) effects on the cardiovascular system in an experimental model of type-1 diabetes","volume":"66","author":"Yousif","year":"2012","journal-title":"Pharmacol. Res."},{"issue":"5","key":"10.1016\/j.virusres.2020.198108_bib1005","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0178525","article-title":"The anti-inflammatory and antioxidant effects of melatonin on LPS-stimulated bovine mammary epithelial cells","volume":"12","author":"Yu","year":"2017","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.virusres.2020.198108_bib1010","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/jpi.12322","article-title":"Melatonin alleviates acute lung injury through inhibiting the NLRP3 inflammasome","volume":"60","author":"Zhang","year":"2016","journal-title":"J. Pineal Res."},{"issue":"7","key":"10.1016\/j.virusres.2020.198108_bib1015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0235458","article-title":"Clinical characteristics of 82 cases of death from COVID-19","volume":"15","author":"Zhang","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.virusres.2020.198108_bib1020","article-title":"COVID-19: melatonin as a potential adjuvant treatment","author":"Zhang","year":"2020","journal-title":"Life Sci."},{"issue":"1","key":"10.1016\/j.virusres.2020.198108_bib1025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0087162","article-title":"Increased risk of wheeze and decreased lung function after respiratory syncytial virus infection","volume":"9","author":"Zomer-Kooijker","year":"2014","journal-title":"PLoS One"}],"container-title":["Virus Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170220310157?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170220310157?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T14:11:22Z","timestamp":1759155082000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168170220310157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":205,"alternative-id":["S0168170220310157"],"URL":"https:\/\/doi.org\/10.1016\/j.virusres.2020.198108","relation":{},"ISSN":["0168-1702"],"issn-type":[{"value":"0168-1702","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Melatonin potentials against viral infections including COVID-19: Current evidence and new findings","name":"articletitle","label":"Article Title"},{"value":"Virus Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virusres.2020.198108","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"198108"}}