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J. Trop. Med. Hyg."},{"key":"10.1016\/j.virusres.2021.198343_bib0455","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aax2388","article-title":"NS1 DNA vaccination protects against Zika infection through T cell-mediated immunity in immunocompetent mice","volume":"5","author":"Grubor-Bauk","year":"2019","journal-title":"Sci. Adv."},{"key":"10.1016\/j.virusres.2021.198343_bib0460","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1128\/CMR.11.3.480","article-title":"Dengue and dengue hemorrhagic fever","volume":"11","author":"Gubler","year":"1998","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.virusres.2021.198343_bib0465","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1006\/viro.1993.1252","article-title":"Selection and partial characterization of dengue 2 virus mutants that induce fusion at elevated pH","volume":"194","author":"Guirakhoo","year":"1993","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2021.198343_bib0470","doi-asserted-by":"crossref","first-page":"5477","DOI":"10.1128\/JVI.74.12.5477-5485.2000","article-title":"Recombinant chimeric yellow fever-dengue type 2 virus is immunogenic and protective in nonhuman primates","volume":"74","author":"Guirakhoo","year":"2000","journal-title":"J. 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World Health Organ."},{"key":"10.1016\/j.virusres.2021.198343_bib0495","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1080\/21645515.2018.1445448","article-title":"Safety issues from a Phase 3 clinical trial of a live-attenuated chimeric yellow fever tetravalent dengue vaccine","volume":"14","author":"Halstead","year":"2018","journal-title":"Hum. Vaccin. Immunother."},{"key":"10.1016\/j.virusres.2021.198343_bib0500","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1093\/jmedent\/45.1.125","article-title":"Culex pipiens (Diptera: culicidae): a bridge vector of West Nile virus to humans","volume":"45","author":"Hamer","year":"2008","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.virusres.2021.198343_bib0505","doi-asserted-by":"crossref","first-page":"13262","DOI":"10.1128\/JVI.79.21.13262-13274.2005","article-title":"N-linked glycosylation of west nile virus envelope proteins influences particle assembly and infectivity","volume":"79","author":"Hanna","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0510","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1083\/jcb.200809175","article-title":"The pH sensor for flavivirus membrane fusion","volume":"183","author":"Harrison","year":"2008","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.virusres.2021.198343_bib0515","doi-asserted-by":"crossref","first-page":"14722","DOI":"10.1038\/ncomms14722","article-title":"A human antibody against Zika virus crosslinks the E protein to prevent infection","volume":"8","author":"Hasan","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.virusres.2021.198343_bib0520","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41594-017-0010-8","article-title":"Structural biology of Zika virus and other flaviviruses","volume":"25","author":"Hasan","year":"2018","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.virusres.2021.198343_bib0525","doi-asserted-by":"crossref","first-page":"17345","DOI":"10.1073\/pnas.1010811107","article-title":"Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis","volume":"107","author":"Heaton","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.virusres.2021.198343_bib0530","first-page":"339","article-title":"The interactions of the flavivirus envelope proteins: implications for virus entry and release","volume":"9","author":"Heinz","year":"1994","journal-title":"Arch. Virol. Suppl."},{"key":"10.1016\/j.virusres.2021.198343_bib0535","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1006\/viro.1994.1013","article-title":"Structural changes and functional control of the tick-borne encephalitis virus glycoprotein E by the heterodimeric association with protein prM","volume":"198","author":"Heinz","year":"1994","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2021.198343_bib0540","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0264-410X(92)90376-U","article-title":"Molecular epidemiology of tick-borne encephalitis virus: Cross-protection between European and Far Eastern subtypes","volume":"10","author":"Holzmann","year":"1992","journal-title":"Vaccine"},{"key":"10.1016\/j.virusres.2021.198343_bib0545","doi-asserted-by":"crossref","first-page":"4119","DOI":"10.3390\/v7072812","article-title":"Amino terminal region of dengue virus NS4A cytosolic domain binds to highly curved liposomes","volume":"7","author":"Hung","year":"2015","journal-title":"Viruses"},{"key":"10.1016\/j.virusres.2021.198343_bib0550","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1038\/nature08476","article-title":"STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity","volume":"461","author":"Ishikawa","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2021.198343_bib0555","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1006\/viro.1994.1481","article-title":"The envelope glycoproteins of dengue 1 and dengue 2 viruses grown in mosquito cells differ in their utilization of potential glycosylation sites","volume":"203","author":"Johnson","year":"1994","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2021.198343_bib0560","doi-asserted-by":"crossref","first-page":"7143","DOI":"10.1128\/JVI.77.12.7143-7149.2003","article-title":"Flavivirus capsid is a dimeric alpha-helical protein","volume":"77","author":"Jones","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0565","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.virol.2004.10.034","article-title":"Construction and applications of yellow fever virus replicons","volume":"331","author":"Jones","year":"2005","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2021.198343_bib0570","doi-asserted-by":"crossref","first-page":"8870","DOI":"10.1128\/JVI.02774-12","article-title":"Role of RNA interference (RNAi) in dengue virus replication and identification of NS4B as an RNAi suppressor","volume":"87","author":"Kakumani","year":"2013","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0575","doi-asserted-by":"crossref","first-page":"11000","DOI":"10.1128\/JVI.01735-06","article-title":"Crystal structure of west nile virus envelope glycoprotein reveals viral surface epitopes","volume":"80","author":"Kanai","year":"2006","journal-title":"J. Virol."},{"issue":"Pt 2","key":"10.1016\/j.virusres.2021.198343_bib0580","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1042\/bj3230415","article-title":"Regulation of N-linked core glycosylation: use of a site-directed mutagenesis approach to identify Asn-Xaa-Ser\/Thr sequons that are poor oligosaccharide acceptors","volume":"323","author":"Kasturi","year":"1997","journal-title":"Biochem. J."},{"key":"10.1016\/j.virusres.2021.198343_bib0585","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/BF01718326","article-title":"RNA binding properties of core protein of the flavivirus Kunjin","volume":"141","author":"Khromykh","year":"1996","journal-title":"Arch. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0590","first-page":"103","article-title":"Studies on arthropod-borne viruses of Tongaland. VIII. Spondweni virus, an agent previously unknown, isolated from Taeniorhynchus (mansonioides) uniformis","volume":"22","author":"Kokernot","year":"1957","journal-title":"S. Afr. J. Med. Sci."},{"key":"10.1016\/j.virusres.2021.198343_bib0595","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/nature17994","article-title":"Structure of the thermally stable Zika virus","volume":"533","author":"Kostyuchenko","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2021.198343_bib0600","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.08347","article-title":"The global distribution of the arbovirus vectors Aedes aegypti and A. albopictus","volume":"4","author":"Kraemer","year":"2015","journal-title":"eLife"},{"key":"10.1016\/j.virusres.2021.198343_bib0605","first-page":"273","article-title":"Isolation of TBE virus from the tick Ixodes hexagonus","volume":"35","author":"Krivanec","year":"1988","journal-title":"Folia Parasitol (Praha)"},{"key":"10.1016\/j.virusres.2021.198343_bib0610","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0092-8674(02)00660-8","article-title":"Structure of dengue virus: implications for flavivirus organization, maturation, and fusion","volume":"108","author":"Kuhn","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.virusres.2021.198343_bib0615","doi-asserted-by":"crossref","first-page":"4773","DOI":"10.1128\/JVI.76.10.4773-4784.2002","article-title":"Mutations in the yellow fever virus nonstructural protein NS2A selectively block production of infectious particles","volume":"76","author":"Kummerer","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0620","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1128\/JVI.72.1.73-83.1998","article-title":"Phylogeny of the genus flavivirus","volume":"72","author":"Kuno","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0625","first-page":"669","article-title":"Vectors of the 1969 yellow fever epidemic on the Jos Plateau, Nigeria","volume":"46","author":"Lee","year":"1972","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.virusres.2021.198343_bib0630","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1006\/viro.1997.8570","article-title":"Changes in the dengue virus major envelope protein on passaging and their localization on the three-dimensional structure of the protein","volume":"232","author":"Lee","year":"1997","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2021.198343_bib0635","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1074\/jbc.M506614200","article-title":"Quantifying the specific binding between West Nile virus envelope domain III protein and the cellular receptor \u03b1V\u03b23 integrin","volume":"281","author":"Lee","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2021.198343_bib0640","doi-asserted-by":"crossref","first-page":"6171","DOI":"10.1128\/JVI.00546-15","article-title":"Determinants of dengue virus NS4A protein oligomerization","volume":"89","author":"Lee","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0645","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0092-8674(01)00303-8","article-title":"The fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH","volume":"105","author":"Lescar","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.virusres.2021.198343_bib0650","doi-asserted-by":"crossref","first-page":"4731","DOI":"10.1128\/JVI.00002-08","article-title":"Role of nonstructural protein NS2A in flavivirus assembly","volume":"82","author":"Leung","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0655","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1126\/science.1153263","article-title":"The flavivirus precursor membrane-envelope protein complex: structure and maturation","volume":"319","author":"Li","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.virusres.2021.198343_bib0660","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1016\/j.bbamem.2015.06.010","article-title":"Membrane topology of NS2B of dengue virus revealed by NMR spectroscopy","volume":"1848","author":"Li","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.virusres.2021.198343_bib0665","doi-asserted-by":"crossref","first-page":"5735","DOI":"10.1128\/JVI.00340-16","article-title":"Transmembrane domains of NS2B contribute to both viral RNA replication and particle formation in japanese encephalitis virus","volume":"90","author":"Li","year":"2016","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0670","doi-asserted-by":"crossref","first-page":"3067","DOI":"10.1038\/s41467-018-05276-4","article-title":"A Zika virus vaccine expressing premembrane-envelope-NS1 polyprotein","volume":"9","author":"Li","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.virusres.2021.198343_bib0675","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/s41422-018-0007-9","article-title":"Structural insight into the Zika virus capsid encapsulating the viral genome","volume":"28","author":"Li","year":"2018","journal-title":"Cell Res."},{"key":"10.1016\/j.virusres.2021.198343_bib0680","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.bbamem.2017.10.016","article-title":"Secondary structure and membrane topology of dengue virus NS4A protein in micelles","volume":"1860","author":"Li","year":"2018","journal-title":"Biochim. Biophys. Acta Biomembr."},{"key":"10.1016\/j.virusres.2021.198343_bib0685","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.stem.2016.07.019","article-title":"Zika virus NS4A and NS4B proteins deregulate Akt-mTOR signaling in human fetal neural stem cells to inhibit neurogenesis and induce autophagy","volume":"19","author":"Liang","year":"2016","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.virusres.2021.198343_bib0690","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1086\/343813","article-title":"High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever","volume":"186","author":"Libraty","year":"2002","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virusres.2021.198343_bib0695","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1128\/JVI.77.4.2600-2606.2003","article-title":"A functional epitope determinant on domain III of the Japanese encephalitis virus envelope protein interacted with neutralizing-antibody combining sites","volume":"77","author":"Lin","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0700","doi-asserted-by":"crossref","first-page":"5908","DOI":"10.1128\/JVI.02714-05","article-title":"Blocking of interferon-induced Jak-Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism","volume":"80","author":"Lin","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0705","doi-asserted-by":"crossref","first-page":"4611","DOI":"10.1128\/JVI.73.6.4611-4621.1999","article-title":"Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function","volume":"73","author":"Lindenbach","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0710","doi-asserted-by":"crossref","first-page":"7804","DOI":"10.1128\/JVI.77.14.7804-7813.2003","article-title":"Molecular and functional analyses of Kunjin virus infectious cDNA clones demonstrate the essential roles for NS2A in virus assembly and for a nonconservative residue in NS3 in RNA replication","volume":"77","author":"Liu","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0715","doi-asserted-by":"crossref","first-page":"5668","DOI":"10.1128\/JVI.00293-15","article-title":"Structure-based mutational analysis of several sites in the E protein: implications for understanding the entry mechanism of Japanese encephalitis virus","volume":"89","author":"Liu","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0720","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/s41541-018-0072-6","article-title":"Incorporation of NS1 and prM\/M are important to confer effective protection of adenovirus-vectored Zika virus vaccine carrying E protein","volume":"3","author":"Liu","year":"2018","journal-title":"NPJ Vaccines"},{"key":"10.1016\/j.virusres.2021.198343_bib0725","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/nsmb.1382","article-title":"Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins","volume":"15","author":"Lok","year":"2008","journal-title":"Nat. Struct. Mol. 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Public Health"},{"key":"10.1016\/j.virusres.2021.198343_bib0740","doi-asserted-by":"crossref","first-page":"23698","DOI":"10.1074\/jbc.M504337200","article-title":"Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals","volume":"280","author":"Lozach","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2021.198343_bib0745","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.celrep.2018.12.065","article-title":"Double lock of a human neutralizing and protective monoclonal antibody targeting the yellow fever virus envelope","volume":"26","author":"Lu","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.virusres.2021.198343_bib0750","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1128\/JVI.06072-11","article-title":"Crystal structure of the Japanese encephalitis virus envelope protein","volume":"86","author":"Luca","year":"2012","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0755","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1128\/JVI.01788-07","article-title":"Crystal structure of the NS3 protease-helicase from dengue virus","volume":"82","author":"Luo","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0760","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.antiviral.2015.03.014","article-title":"The flavivirus NS2B-NS3 protease-helicase as a target for antiviral drug development","volume":"118","author":"Luo","year":"2015","journal-title":"Antiviral Res."},{"key":"10.1016\/j.virusres.2021.198343_bib0765","doi-asserted-by":"crossref","first-page":"3414","DOI":"10.1073\/pnas.0305892101","article-title":"Solution structure of dengue virus capsid protein reveals another fold","volume":"101","author":"Ma","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.virusres.2021.198343_bib0770","doi-asserted-by":"crossref","first-page":"10678","DOI":"10.1074\/jbc.M607273200","article-title":"Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5","volume":"282","author":"Malet","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2021.198343_bib0775","doi-asserted-by":"crossref","first-page":"411","DOI":"10.4269\/ajtmh.1969.18.411","article-title":"Isolation of Zika virus from Aedes aegypti mosquitoes in Malaysia","volume":"18","author":"Marchette","year":"1969","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.virusres.2021.198343_bib0780","doi-asserted-by":"crossref","first-page":"3345","DOI":"10.1128\/jvi.63.8.3345-3352.1989","article-title":"In vitro processing of dengue virus structural proteins: cleavage of the pre-membrane protein","volume":"63","author":"Markoff","year":"1989","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0785","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1006\/viro.1994.1566","article-title":"Processing of flavivirus structural glycoproteins: Stable membrane insertion of premembrane requires the envelope signal peptide","volume":"204","author":"Markoff","year":"1994","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2021.198343_bib0790","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1006\/viro.1997.8608","article-title":"A conserved internal hydrophobic domain mediates the stable membrane integration of the dengue virus capsid protein","volume":"233","author":"Markoff","year":"1997","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2021.198343_bib0795","first-page":"17","article-title":"The nature and metabolism of the carbohydrate-peptide linkages of glycoproteins","author":"Marshall","year":"1974","journal-title":"Biochem. Soc. Symp."},{"key":"10.1016\/j.virusres.2021.198343_bib0800","doi-asserted-by":"crossref","first-page":"W597","DOI":"10.1093\/nar\/gkt376","article-title":"Analysis tool web services from the EMBL-EBI","volume":"41","author":"McWilliam","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.virusres.2021.198343_bib0805","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1099\/vir.0.82883-0","article-title":"Complete genome characterization of Rocio virus (Flavivirus: flaviviridae), a Brazilian flavivirus isolated from a fatal case of encephalitis during an epidemic in Sao Paulo state","volume":"88","author":"Medeiros","year":"2007","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0810","doi-asserted-by":"crossref","first-page":"6833","DOI":"10.1021\/bi972217k","article-title":"The amino acid following an asn-X-Ser\/Thr sequon is an important determinant of N-linked core glycosylation efficiency","volume":"37","author":"Mellquist","year":"1998","journal-title":"Biochemistry"},{"key":"10.1016\/j.virusres.2021.198343_bib0815","doi-asserted-by":"crossref","first-page":"8854","DOI":"10.1074\/jbc.M512697200","article-title":"Subcellular localization and membrane topology of the Dengue virus type 2 non-structural protein 4B","volume":"281","author":"Miller","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2021.198343_bib0820","doi-asserted-by":"crossref","first-page":"8873","DOI":"10.1074\/jbc.M609919200","article-title":"The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner","volume":"282","author":"Miller","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2021.198343_bib0825","doi-asserted-by":"crossref","first-page":"465","DOI":"10.4269\/ajtmh.1981.30.465","article-title":"Experimental transmission of Rocio virus by mosquitoes","volume":"30","author":"Mitchell","year":"1981","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.virusres.2021.198343_bib0830","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1056\/NEJMoa1600651","article-title":"Zika virus associated with microcephaly","volume":"374","author":"Mlakar","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.virusres.2021.198343_bib0835","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1126\/science.abb9425","article-title":"A broadly protective antibody that targets the flavivirus NS1 protein","volume":"371","author":"Modhiran","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.virusres.2021.198343_bib0840","doi-asserted-by":"crossref","first-page":"6986","DOI":"10.1073\/pnas.0832193100","article-title":"A ligand-binding pocket in the dengue virus envelope glycoprotein","volume":"100","author":"Modis","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.virusres.2021.198343_bib0845","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/nature02165","article-title":"Structure of the dengue virus envelope protein after membrane fusion","volume":"427","author":"Modis","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2021.198343_bib0850","doi-asserted-by":"crossref","first-page":"7136","DOI":"10.1128\/JVI.00116-07","article-title":"Essential role of dengue virus envelope protein N glycosylation at asparagine-67 during viral propagation","volume":"81","author":"Mondotte","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0855","doi-asserted-by":"crossref","first-page":"3112","DOI":"10.1038\/s41467-020-16925-y","article-title":"High flavivirus structural plasticity demonstrated by a non-spherical morphological variant","volume":"11","author":"Morrone","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.virusres.2021.198343_bib0860","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jim.2009.11.006","article-title":"Optimization of a dendritic cell-based assay for the in vitro priming of naive human CD4+ T cells","volume":"353","author":"Moser","year":"2010","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.virusres.2021.198343_bib0865","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1126\/science.1089316","article-title":"Structure of West Nile virus","volume":"302","author":"Mukhopadhyay","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.virusres.2021.198343_bib0870","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/nrmicro1067","article-title":"A structural perspective of the flavivirus life cycle","volume":"3","author":"Mukhopadhyay","year":"2005","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.virusres.2021.198343_bib0875","doi-asserted-by":"crossref","first-page":"14333","DOI":"10.1073\/pnas.2335168100","article-title":"Inhibition of interferon signaling by dengue virus","volume":"100","author":"Munoz-Jordan","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.virusres.2021.198343_bib0880","doi-asserted-by":"crossref","first-page":"e1065","DOI":"10.1016\/S2214-109X(19)30250-5","article-title":"Burden of dengue infection in India, 2017: A cross-sectional population based serosurvey","volume":"7","author":"Murhekar","year":"2019","journal-title":"Lancet Glob. Health"},{"key":"10.1016\/j.virusres.2021.198343_bib0885","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1038\/nrmicro1928","article-title":"Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis","volume":"6","author":"Murray","year":"2008","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.virusres.2021.198343_bib0890","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/sj.embor.embor866","article-title":"Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses","volume":"4","author":"Navarro-Sanchez","year":"2003","journal-title":"EMBO Rep."},{"key":"10.1016\/j.virusres.2021.198343_bib0895","doi-asserted-by":"crossref","first-page":"12631","DOI":"10.1128\/JVI.01072-09","article-title":"Protonation of individual histidine residues is not required for the pH-dependent entry of West Nile virus: Evaluation of the \u201chistidine switch\u201d hypothesis","volume":"83","author":"Nelson","year":"2009","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0900","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.virusres.2009.11.012","article-title":"Nuclear localization of dengue virus capsid protein is required for DAXX interaction and apoptosis","volume":"147","author":"Netsawang","year":"2010","journal-title":"Virus Res."},{"key":"10.1016\/j.virusres.2021.198343_bib0905","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1038\/nature03956","article-title":"Structural basis of West Nile virus neutralization by a therapeutic antibody","volume":"437","author":"Nybakken","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2021.198343_bib0910","doi-asserted-by":"crossref","first-page":"11467","DOI":"10.1128\/JVI.01125-06","article-title":"Crystal structure of the West Nile virus envelope glycoprotein","volume":"80","author":"Nybakken","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0915","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1007\/s10822-017-0076-8","article-title":"New insights into flavivirus biology: the influence of pH over interactions between prM and E proteins","volume":"31","author":"Oliveira","year":"2017","journal-title":"J. Comput. Aided Mol. Des."},{"key":"10.1016\/j.virusres.2021.198343_bib0920","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1093\/infdis\/jir122","article-title":"A tick-borne encephalitis virus vaccine based on the European prototype strain induces broadly reactive cross-neutralizing antibodies in humans","volume":"203","author":"Orlinger","year":"2011","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virusres.2021.198343_bib0925","series-title":"Reported Cases of Dengue Fever in the Americas","author":"PAHO","year":"2020"},{"key":"10.1016\/j.virusres.2021.198343_bib0930","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1146\/annurev-virology-100114-055007","article-title":"Flaviviridae replication organelles: Oh, what a tangled web we weave","volume":"2","author":"Paul","year":"2015","journal-title":"Annu. Rev. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib0935","doi-asserted-by":"crossref","first-page":"e2318","DOI":"10.1371\/journal.pntd.0002318","article-title":"Ilheus virus isolation in the Pantanal, west-central Brazil","volume":"7","author":"Pauvolid-Correa","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.virusres.2021.198343_bib0940","first-page":"50","article-title":"A cultured concentrated inactivated vaccine against tick-borne encephalitis studied during the immunization of children and adolescents","author":"Pavlova","year":"1999","journal-title":"Zh. Mikrobiol. Epidemiol. Immunobiol."},{"key":"10.1016\/j.virusres.2021.198343_bib0945","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0038202","article-title":"Early dengue virus protein synthesis induces extensive rearrangement of the endoplasmic reticulum independent of the UPR and SREBP-2 pathway","volume":"7","author":"Pena","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.virusres.2021.198343_bib0950","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1017\/S0950268812001070","article-title":"Estimated cumulative incidence of West Nile virus infection in US adults, 1999-2010","volume":"141","author":"Petersen","year":"2013","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.virusres.2021.198343_bib0955","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1002\/jcc.20084","article-title":"UCSF Chimera: A visualization system for exploratory research and analysis","volume":"25","author":"Pettersen","year":"2004","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.virusres.2021.198343_bib0960","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1038\/s41564-020-0714-0","article-title":"The continued threat of emerging flaviviruses","volume":"5","author":"Pierson","year":"2020","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.virusres.2021.198343_bib0965","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007736","article-title":"A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle","volume":"15","author":"Plaszczyca","year":"2019","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virusres.2021.198343_bib0970","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/0042-6822(90)90073-Z","article-title":"Nucleotide sequence of the genome and complete amino acid sequence of the polyprotein of tick-borne encephalitis virus","volume":"174","author":"Pletnev","year":"1990","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2021.198343_bib0975","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1038\/embor.2011.75","article-title":"Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres","volume":"12","author":"Plevka","year":"2011","journal-title":"EMBO Rep."},{"key":"10.1016\/j.virusres.2021.198343_bib0980","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.cell.2005.11.042","article-title":"Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN","volume":"124","author":"Pokidysheva","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.virusres.2021.198343_bib0985","doi-asserted-by":"crossref","first-page":"2575","DOI":"10.1016\/j.febslet.2011.06.038","article-title":"RNA binding property and RNA chaperone activity of dengue virus core protein and other viral RNA-interacting proteins","volume":"585","author":"Pong","year":"2011","journal-title":"FEBS Lett."},{"key":"10.1016\/j.virusres.2021.198343_bib0990","doi-asserted-by":"crossref","DOI":"10.3390\/v11070623","article-title":"Crystal structure of the Japanese encephalitis virus capsid protein","volume":"11","author":"Poonsiri","year":"2019","journal-title":"Viruses"},{"key":"10.1016\/j.virusres.2021.198343_bib0995","doi-asserted-by":"crossref","DOI":"10.1590\/0074-02760180278","article-title":"Yellow fever outbreak in Brazil: The puzzle of rapid viral spread and challenges for immunisation","volume":"113","author":"Possas","year":"2018","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"10.1016\/j.virusres.2021.198343_bib1000","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.bpj.2010.04.024","article-title":"Probing the mechanism of pH-induced large-scale conformational changes in dengue virus envelope protein using atomistic simulations","volume":"99","author":"Prakash","year":"2010","journal-title":"Biophys. J."},{"key":"10.1016\/j.virusres.2021.198343_bib1005","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/nsmb.3352","article-title":"Structure of the immature Zika virus at 9 \u00c5 resolution","volume":"24","author":"Prasad","year":"2017","journal-title":"Nat. Struct. Mol. Biol."},{"issue":"Pt 5","key":"10.1016\/j.virusres.2021.198343_bib1010","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1099\/0022-1317-75-5-1183","article-title":"Glycosylation mutants of dengue virus NS1 protein","volume":"75","author":"Pryor","year":"1994","journal-title":"J. Gen. Virol."},{"issue":"Pt 11","key":"10.1016\/j.virusres.2021.198343_bib1015","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1099\/0022-1317-79-11-2631","article-title":"Growth restriction of dengue virus type 2 by site-specific mutagenesis of virus-encoded glycoproteins","volume":"79","author":"Pryor","year":"1998","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1020","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0042-6822(88)90236-X","article-title":"Functional and antigenic domains of the dengue-2 virus nonstructural glycoprotein NS-1","volume":"163","author":"Putnak","year":"1988","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2021.198343_bib1025","first-page":"1179","article-title":"Isolation of tick-borne encephalitis virus from ticks Ixodes ricinus","volume":"88","author":"Rampas","year":"1949","journal-title":"\u010cas L\u00e9k \u010des"},{"key":"10.1016\/j.virusres.2021.198343_bib1030","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.tim.2018.05.010","article-title":"Lipid droplet metabolism during dengue virus infection","volume":"26","author":"Randall","year":"2018","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.virusres.2021.198343_bib1035","doi-asserted-by":"crossref","first-page":"90","DOI":"10.4269\/ajtmh.1998.58.90","article-title":"Conversion of dengue virus replicative form RNA (RF) to replicative intermediate (RI) by nonstructural proteins NS-5 and NS-3","volume":"58","author":"Raviprakash","year":"1998","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.virusres.2021.198343_bib1040","first-page":"37","article-title":"The etiology of Yellow fever: A preliminary note","volume":"26","author":"Reed","year":"1900","journal-title":"Public Health Pap. Rep."},{"key":"10.1016\/j.virusres.2021.198343_bib1045","doi-asserted-by":"crossref","first-page":"662","DOI":"10.2987\/8756-971X(2006)22[662:VCOCIA]2.0.CO;2","article-title":"Vector competence of Culiseta incidens and Culex thriambus for West Nile virus","volume":"22","author":"Reisen","year":"2006","journal-title":"J. Am. Mosq. Control Assoc."},{"key":"10.1016\/j.virusres.2021.198343_bib1050","article-title":"A high resolution view of an adolescent flavivirus","author":"Renner","year":"2020","journal-title":"bioRxiv."},{"key":"10.1016\/j.virusres.2021.198343_bib1055","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/j.cell.2018.02.054","article-title":"Common features of enveloped viruses and implications for immunogen design for next-generation vaccines","volume":"172","author":"Rey","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.virusres.2021.198343_bib1060","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/375291a0","article-title":"The envelope glycoprotein from tick-borne encephalitis virus at 2 \u00c5 resolution","volume":"375","author":"Rey","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.virusres.2021.198343_bib1065","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.coviro.2017.06.009","article-title":"Flavivirus structural heterogeneity: Implications for cell entry","volume":"24","author":"Rey","year":"2017","journal-title":"Curr. Opin. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1070","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1126\/science.4023707","article-title":"Nucleotide sequence of yellow fever virus: Implications for flavivirus gene expression and evolution","volume":"229","author":"Rice","year":"1985","journal-title":"Science"},{"key":"10.1016\/j.virusres.2021.198343_bib1075","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1073\/pnas.1620558114","article-title":"AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses","volume":"114","author":"Richard","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. 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Biol."},{"key":"10.1016\/j.virusres.2021.198343_bib1150","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1099\/vir.0.012864-0","article-title":"NS4A regulates the ATPase activity of the NS3 helicase: A novel cofactor role of the non-structural protein NS4A from West Nile virus","volume":"90","author":"Shiryaev","year":"2009","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1155","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/msb.2011.75","article-title":"Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega","volume":"7","author":"Sievers","year":"2011","journal-title":"Mol. Syst. Biol."},{"key":"10.1016\/j.virusres.2021.198343_bib1160","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1099\/jgv.0.000672","article-title":"ICTV virus taxonomy profile: Flaviviridae","volume":"98","author":"Simmonds","year":"2017","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1165","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1093\/infdis\/jiv023","article-title":"A Japanese encephalitis vaccine from India induces durable and cross-protective immunity against temporally and spatially wide-ranging global field strains","volume":"212","author":"Singh","year":"2015","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virusres.2021.198343_bib1170","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1126\/science.aaf5316","article-title":"The 3.8 \u00c5 resolution cryo-EM structure of Zika virus","volume":"352","author":"Sirohi","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.virusres.2021.198343_bib1175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01240711","article-title":"Experimenteller und epidemiologischer Beitrag zur activen Immunisierung gegen die Fruhling-Sommer-zecken-encephalitis","volume":"2","author":"Smorodintseff","year":"1941","journal-title":"Arch Ges Virusforsch"},{"key":"10.1016\/j.virusres.2021.198343_bib1180","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/nsmb.3213","article-title":"Zika virus NS1 structure reveals diversity of electrostatic surfaces among flaviviruses","volume":"23","author":"Song","year":"2016","journal-title":"Nat. Struct. Mol. 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Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1190","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1126\/science.aaf8505","article-title":"Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection","volume":"353","author":"Stettler","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.virusres.2021.198343_bib1195","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1007\/s00726-009-0370-4","article-title":"Molecular mechanisms of flavivirus membrane fusion","volume":"41","author":"Stiasny","year":"2011","journal-title":"Amino Acids"},{"key":"10.1016\/j.virusres.2021.198343_bib1200","doi-asserted-by":"crossref","first-page":"9227","DOI":"10.1128\/JVI.01087-10","article-title":"Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2","volume":"84","author":"Sukupolvi-Petty","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1205","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01123-16","article-title":"Dengue virus envelope dimer epitope monoclonal antibodies isolated from dengue patients are protective against zika virus","volume":"7","author":"Swanstrom","year":"2016","journal-title":"mBio"},{"key":"10.1016\/j.virusres.2021.198343_bib1210","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s11262-008-0211-7","article-title":"Characterization of Asn130-to-Ala mutant of dengue type 1 virus NS1 protein","volume":"36","author":"Tajima","year":"2008","journal-title":"Virus Genes"},{"key":"10.1016\/j.virusres.2021.198343_bib1215","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/s41467-020-14647-9","article-title":"Capsid protein structure in Zika virus reveals the flavivirus assembly process","volume":"11","author":"Tan","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.virusres.2021.198343_bib1220","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1084\/jem.20021840","article-title":"DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells","volume":"197","author":"Tassaneetrithep","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.virusres.2021.198343_bib1225","doi-asserted-by":"crossref","first-page":"2529","DOI":"10.1016\/j.vaccine.2019.03.030","article-title":"Persistence of the immune response after vaccination with the Japanese encephalitis vaccine, IXIARO\u00ae in healthy adults: A five year follow-up study","volume":"37","author":"Taucher","year":"2019","journal-title":"Vaccine"},{"key":"10.1016\/j.virusres.2021.198343_bib1230","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005886","article-title":"The C-terminal 18 amino acid region of dengue virus NS5 regulates its subcellular localization and contains a conserved arginine residue essential for infectious virus production","volume":"12","author":"Tay","year":"2016","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virusres.2021.198343_bib1235","first-page":"5","article-title":"Epidemiologia e medidas de preven\u00e7\u00e3o do dengue","volume":"8","author":"Teixeira","year":"1999","journal-title":"Inf. Epidemiol. Sus."},{"key":"10.1016\/j.virusres.2021.198343_bib1240","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1128\/JVI.01249-13","article-title":"Cellular vimentin regulates construction of dengue virus replication complexes through interaction with NS4A protein","volume":"88","author":"Teo","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1245","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1084\/jem.65.6.767","article-title":"The effect of prolonged cultivation in vitro upon the pathogenicity of yellow fever virus","volume":"65","author":"Theiler","year":"1937","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.virusres.2021.198343_bib1250","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1084\/jem.65.6.787","article-title":"The use of yellow fever virus modified by in vitro cultivation for human immunization","volume":"65","author":"Theiler","year":"1937","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.virusres.2021.198343_bib1255","doi-asserted-by":"crossref","first-page":"11608","DOI":"10.1073\/pnas.1809304115","article-title":"Flaviviruses have imperfect icosahedral symmetry","volume":"115","author":"Therkelsen","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.virusres.2021.198343_bib1260","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1080\/21645515.2019.1658503","article-title":"A review of Dengvaxia(R): development to deployment","volume":"15","author":"Thomas","year":"2019","journal-title":"Hum. Vaccin. Immunother."},{"key":"10.1016\/j.virusres.2021.198343_bib1265","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1099\/0022-1317-82-8-1885","article-title":"Mapping of a dengue virus neutralizing epitope critical for the infectivity of all serotypes: insight into the neutralization mechanism","volume":"82","author":"Thullier","year":"2001","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1270","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1743-422X-2-25","article-title":"Two dimensional VOPBA reveals laminin receptor (LAMR1) interaction with dengue virus serotypes 1, 2 and 3","volume":"2","author":"Tio","year":"2005","journal-title":"Virol. J."},{"key":"10.1016\/j.virusres.2021.198343_bib1275","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1099\/vir.0.81844-0","article-title":"Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA","volume":"87","author":"Umareddy","year":"2006","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1280","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1093\/trstmh\/trz031","article-title":"Detection of Ilheus virus in mosquitoes from southeast Amazon, Brazil","volume":"113","author":"Vieira","year":"2019","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.virusres.2021.198343_bib1285","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1056\/NEJMoa1411037","article-title":"Efficacy of a tetravalent dengue vaccine in children in Latin America","volume":"372","author":"Villar","year":"2015","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.virusres.2021.198343_bib1290","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1093\/jmedent\/45.3.483","article-title":"Arbovirus transmission by Culex nigripalpus in Florida, 2005","volume":"45","author":"Vitek","year":"2008","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.virusres.2021.198343_bib1295","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0092495","article-title":"Protection against dengue virus infection in mice by administration of antibodies against modified nonstructural protein 1","volume":"9","author":"Wan","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.virusres.2021.198343_bib1300","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aai8336","article-title":"Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus","volume":"8","author":"Wang","year":"2016","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.virusres.2021.198343_bib1305","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/s41467-017-00024-6","article-title":"Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability","volume":"8","author":"Wang","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.virusres.2021.198343_bib1310","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007287","article-title":"Interferon-stimulated TRIM69 interrupts dengue virus replication by ubiquitinating viral nonstructural protein 3","volume":"14","author":"Wang","year":"2018","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virusres.2021.198343_bib1315","doi-asserted-by":"crossref","first-page":"652","DOI":"10.3201\/eid0807.020094","article-title":"Emergence of Usutu virus, an African mosquito-borne flavivirus of the Japanese encephalitis virus group, central Europe","volume":"8","author":"Weissenbock","year":"2002","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.virusres.2021.198343_bib1320","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.chom.2009.03.007","article-title":"Composition and three-dimensional architecture of the dengue virus replication and assembly sites","volume":"5","author":"Welsch","year":"2009","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.virusres.2021.198343_bib1325","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1089\/vbz.2012.1181","article-title":"Human cases of Wesselsbron disease, South Africa 2010-2011","volume":"13","author":"Weyer","year":"2013","journal-title":"Vector Borne Zoonotic Dis."},{"key":"10.1016\/j.virusres.2021.198343_bib1330","doi-asserted-by":"crossref","first-page":"4848","DOI":"10.1016\/j.vaccine.2018.09.063","article-title":"Dengue vaccine: WHO position paper, September 2018 - Recommendations","volume":"37","author":"WHO","year":"2019","journal-title":"Vaccine"},{"key":"10.1016\/j.virusres.2021.198343_bib1335","series-title":"Yellow Fever - Nigeria","author":"WHO","year":"2019"},{"key":"10.1016\/j.virusres.2021.198343_bib1340","series-title":"Dengue and Severe Dengue","author":"WHO","year":"2020"},{"key":"10.1016\/j.virusres.2021.198343_bib1345","series-title":"Yellow Fever Resurgence : Impact of Mass Vaccination Campaigns","author":"WHO","year":"2020"},{"key":"10.1016\/j.virusres.2021.198343_bib1350","first-page":"531","article-title":"Protein identification and analysis tools in the ExPASy server","volume":"112","author":"Wilkins","year":"1999","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.virusres.2021.198343_bib1355","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0042-6822(88)90408-4","article-title":"Evidence that the mature form of the flavivirus nonstructural protein NS1 is a dimer","volume":"162","author":"Winkler","year":"1988","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2021.198343_bib1360","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/0042-6822(89)90544-8","article-title":"Newly synthesized dengue-2 virus nonstructural protein NS1 is a soluble protein but becomes partially hydrophobic and membrane-associated after dimerization","volume":"171","author":"Winkler","year":"1989","journal-title":"Virology"},{"key":"10.1016\/j.virusres.2021.198343_bib1365","doi-asserted-by":"crossref","first-page":"46007","DOI":"10.1074\/jbc.M307776200","article-title":"Structural basis of a flavivirus recognized by its neutralizing antibody: solution structure of the domain III of the Japanese encephalitis virus envelope protein","volume":"278","author":"Wu","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virusres.2021.198343_bib1370","doi-asserted-by":"crossref","first-page":"4281","DOI":"10.1128\/JVI.03011-14","article-title":"Scanning mutagenesis studies reveal a potential intramolecular interaction within the C-terminal half of dengue virus NS2A involved in viral RNA replication and virus assembly and secretion","volume":"89","author":"Wu","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1375","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1128\/JVI.02882-14","article-title":"Two distinct sets of NS2A molecules are responsible for dengue virus RNA synthesis and virion assembly","volume":"89","author":"Xie","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1380","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.chom.2019.09.015","article-title":"Dengue NS2A protein orchestrates virus assembly","volume":"26","author":"Xie","year":"2019","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.virusres.2021.198343_bib1385","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.15252\/embj.201695290","article-title":"Contribution of intertwined loop to membrane association revealed by Zika virus full-length NS1 structure","volume":"35","author":"Xu","year":"2016","journal-title":"EMBO J."},{"key":"10.1016\/j.virusres.2021.198343_bib1390","first-page":"165","article-title":"West Nile virus capsid protein induces p53-mediated apoptosis via the sequestration of HDM2 to the nucleolus","volume":"10","author":"Yang","year":"2008","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.virusres.2021.198343_bib1395","doi-asserted-by":"crossref","first-page":"4753","DOI":"10.1128\/JVI.02283-06","article-title":"Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution","volume":"81","author":"Yap","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virusres.2021.198343_bib1400","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.3389\/fmicb.2017.01415","article-title":"Dengue virus glycosylation: What do we know?","volume":"8","author":"Yap","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.virusres.2021.198343_bib1405","doi-asserted-by":"crossref","first-page":"2704","DOI":"10.4161\/hv.29509","article-title":"Reduction of neutralization antibody against heterologous circulating strains in adults immunized with Japanese encephalitis live vaccine","volume":"10","author":"Ye","year":"2014","journal-title":"Hum. Vaccin. 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