{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:47:31Z","timestamp":1761864451651,"version":"3.44.0"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["BT\/PR30819\/MED\/29\/1368\/2019"],"award-info":[{"award-number":["BT\/PR30819\/MED\/29\/1368\/2019"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001412","name":"Council of Scientific and Industrial Research, India","doi-asserted-by":"publisher","award":["09\/0591(11545)\/2021-EMR-I"],"award-info":[{"award-number":["09\/0591(11545)\/2021-EMR-I"]}],"id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virus Research"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.virusres.2022.198887","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T21:36:35Z","timestamp":1659994595000},"page":"198887","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Novel insights into host responses to Japanese Encephalitis Virus infection: Reanalysis of public transcriptome and microRNAome datasets"],"prefix":"10.1016","volume":"320","author":[{"given":"Roopali","family":"Rajput","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neha","family":"Periwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chitranjan","family":"Mukherjee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priyanshu","family":"Verma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jitender","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooja","family":"Arora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baljeet","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikas","family":"Sood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.virusres.2022.198887_bib0001","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.neulet.2006.11.070","article-title":"Induction of IP-10 (CXCL10) in astrocytes following Japanese encephalitis","volume":"414","author":"Bhowmick","year":"2007","journal-title":"Neurosci. Lett."},{"issue":"12","key":"10.1016\/j.virusres.2022.198887_bib0002","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1002\/glia.20848","article-title":"Astrocyte function and role in motor neuron disease: a future therapeutic target?","volume":"57","author":"Blackburn","year":"2009","journal-title":"Glia"},{"issue":"21","key":"10.1016\/j.virusres.2022.198887_bib0003","doi-asserted-by":"crossref","first-page":"10455","DOI":"10.1128\/JVI.00438-08","article-title":"The cellular antiviral protein viperin is attenuated by proteasome-mediated protein degradation in Japanese encephalitis virus-infected cells","volume":"82","author":"Chan","year":"2008","journal-title":"J. Virol."},{"issue":"39","key":"10.1016\/j.virusres.2022.198887_bib0004","doi-asserted-by":"crossref","first-page":"25414","DOI":"10.18632\/oncotarget.11003","article-title":"miR-513a-5p regulates radiosensitivity of osteosarcoma by targeting human apurinic\/apyrimidinic endonuclease","volume":"9","author":"Dai","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.virusres.2022.198887_bib0005","doi-asserted-by":"crossref","first-page":"10693","DOI":"10.2147\/CMAR.S266575","article-title":"LncRNA ADAMTS9-AS1 Restrains the Aggressive Traits of Breast Carcinoma Cells via Sponging miR-513a-5p","volume":"12","author":"Fang","year":"2020","journal-title":"Cancer Manag. Res."},{"issue":"20","key":"10.1016\/j.virusres.2022.198887_bib0006","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1111\/1759-7714.14111","article-title":"Long noncoding RNA ZBED3-AS1 restrains breast cancer progression by targeting the microRNA-513a-5p\/KLF6 axis","volume":"12","author":"Fu","year":"2021","journal-title":"Thorac. Cancer."},{"key":"10.1016\/j.virusres.2022.198887_bib0007","unstructured":"Gene Cards, 2022. PAQR8. Available at: https:\/\/www.genecards.org\/cgi-bin\/carddisp.pl?gene=PAQR8."},{"key":"10.1016\/j.virusres.2022.198887_bib0008","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/j.biopha.2018.09.112","article-title":"Through oxaliplatin resistance induction in colorectal cancer cells, increasing ABCB1 level accompanies decreasing level of miR-302c-5p, miR-3664-5p and miR-129-5p","volume":"108","author":"Ghanbarian","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"11","key":"10.1016\/j.virusres.2022.198887_bib0009","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.7150\/jca.50403","article-title":"Long non-coding RNA BLACAT2 promotes gastric cancer progression via the miR-193b-5p\/METTL3 pathway","volume":"12","author":"Hu","year":"2021","journal-title":"J. Cancer"},{"issue":"3","key":"10.1016\/j.virusres.2022.198887_bib0010","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.21037\/tcr.2020.02.14","article-title":"MiR-193b-5p inhibits proliferation and enhances radio-sensitivity by downregulating the AKT\/mTOR signaling pathway in tongue cancer","volume":"9","author":"Jiang","year":"2020","journal-title":"Transl. Cancer Res."},{"issue":"7089","key":"10.1016\/j.virusres.2022.198887_bib0011","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/nature04734","article-title":"Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses","volume":"441","author":"Kato","year":"2006","journal-title":"Nature"},{"issue":"9","key":"10.1016\/j.virusres.2022.198887_bib0012","doi-asserted-by":"crossref","first-page":"4446","DOI":"10.4049\/jimmunol.1500204","article-title":"ATF3 is a key regulator of macrophage IFN responses","volume":"195","author":"Labzin","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.virusres.2022.198887_bib0013","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1186\/s12885-015-1102-7","article-title":"Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive value","volume":"15","author":"Lehmann","year":"2015","journal-title":"BMC Cancer"},{"key":"10.1016\/j.virusres.2022.198887_bib0014","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/j.biopha.2018.09.101","article-title":"miR-513a-5p targets Bcl-2 to promote dichlorvos induced apoptosis in HK-2 cells","volume":"108","author":"Li","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.virusres.2022.198887_bib0015","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.immuni.2012.11.005","article-title":"Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol","volume":"38","author":"Liu","year":"2013","journal-title":"Immunity"},{"issue":"3","key":"10.1016\/j.virusres.2022.198887_bib0016","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1161\/CIRCGENETICS.113.000455","article-title":"A point mutation in MYH10 causes major defects in heart development and body wall closure","volume":"7","author":"Ma","year":"2014","journal-title":"Circ. Cardiovasc. Genet."},{"issue":"2","key":"10.1016\/j.virusres.2022.198887_bib0017","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1093\/carcin\/bgx126","article-title":"MiRNA-513a-5p inhibits progesterone receptor expression and constitutes a risk factor for breast cancer: the hOrmone and Diet in the ETiology of breast cancer prospective study","volume":"39","author":"Muti","year":"2018","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.virusres.2022.198887_bib0018","doi-asserted-by":"crossref","unstructured":"Pandian, S., Zhao, J.P., Murata, Y., Bustos, F.J., Tunca, C., Almeida, R.D., Constantine-Paton, M. 2020. Myosin Va brain-specific mutation alters mouse behavior and disrupts hippocampal synapses. eNeuro. 7(6), ENEURO.0284-20.2020. https:\/\/doi.org\/10.1523\/ENEURO.0284-20.2020.","DOI":"10.1523\/ENEURO.0284-20.2020"},{"key":"10.1016\/j.virusres.2022.198887_bib0019","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jnutbio.2018.09.024","article-title":"Quercetin inhibits proliferation of endometriosis regulating cyclin D1 and its target microRNAs in vitro and in vivo","volume":"63","author":"Park","year":"2019","journal-title":"J. Nutr. Biochem."},{"issue":"1","key":"10.1016\/j.virusres.2022.198887_bib0020","doi-asserted-by":"crossref","first-page":"3512","DOI":"10.1038\/s41467-019-11461-w","article-title":"Quantifying the impact of public omics data","volume":"10","author":"Perez-Riverol","year":"2019","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.virusres.2022.198887_bib0021","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1093\/bib\/bbab118","article-title":"Analyzing master regulators and scRNA-seq of COVID-19 patients reveals an underlying anti-SARS-CoV-2 mechanism of ZNF proteins","volume":"22","author":"Qin","year":"2021","journal-title":"Brief. Bioinform."},{"issue":"11","key":"10.1016\/j.virusres.2022.198887_bib0022","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome. Res."},{"key":"10.1016\/j.virusres.2022.198887_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2021.100994","article-title":"Pathobiology of Japanese encephalitis virus infection","volume":"81","author":"Sharma","year":"2021","journal-title":"Mol. Aspects. Med."},{"key":"10.1016\/j.virusres.2022.198887_bib0024","doi-asserted-by":"crossref","first-page":"8789","DOI":"10.1038\/s41598-017-08584-9","article-title":"ATF3 negatively regulates cellular antiviral signaling and autophagy in the absence of type I interferons","volume":"7","author":"Sood","year":"2017","journal-title":"Sci. Rep."},{"issue":"D1","key":"10.1016\/j.virusres.2022.198887_bib0025","doi-asserted-by":"crossref","first-page":"D607","DOI":"10.1093\/nar\/gky1131","article-title":"STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets","volume":"47","author":"Szklarczyk","year":"2019","journal-title":"Nucleic Acids Res."},{"issue":"D1","key":"10.1016\/j.virusres.2022.198887_bib0026","doi-asserted-by":"crossref","first-page":"D360","DOI":"10.1093\/nar\/gkx1144","article-title":"mirDIP 4.1-integrative database of human microRNA target predictions","volume":"46","author":"Tokar","year":"2018","journal-title":"Nucleic Acids Res."},{"issue":"5","key":"10.1016\/j.virusres.2022.198887_bib0027","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/nrneurol.2018.30","article-title":"Japanese encephalitis - the prospects for new treatments","volume":"14","author":"Turtle","year":"2018","journal-title":"Nat. Rev. Neurol."},{"issue":"1","key":"10.1016\/j.virusres.2022.198887_bib0028","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1186\/s12935-021-02353-5","article-title":"Long noncoding RNA CRART16 confers 5-FU resistance in colorectal cancer cells by sponging miR-193b-5p","volume":"21","author":"Wang","year":"2021","journal-title":"Cancer Cell. Int."},{"key":"10.1016\/j.virusres.2022.198887_bib0029","doi-asserted-by":"crossref","first-page":"12846","DOI":"10.1038\/ncomms12846","article-title":"Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd","volume":"7","author":"Wang","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.virusres.2022.198887_bib0030","unstructured":"WHO 2019. Fact sheets. Japanese encephalitis. Available at: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/japanese-encephalitis."},{"issue":"10","key":"10.1016\/j.virusres.2022.198887_bib0031","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1038\/gim.2017.246","article-title":"Making new genetic diagnoses with old data: iterative reanalysis and reporting from genome-wide data in 1,133 families with developmental disorders","volume":"20","author":"Wright","year":"2018","journal-title":"Genet. Med."},{"issue":"3","key":"10.1016\/j.virusres.2022.198887_bib0032","article-title":"clusterProfiler 4.0: a universal enrichment tool for interpreting omics data","volume":"2","author":"Wu","year":"2021","journal-title":"Innovation (Camb)"},{"key":"10.1016\/j.virusres.2022.198887_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2021.112059","article-title":"MiR-193b-5p protects BRL-3A cells from acrylamide-induced cell cycle arrest by targeting FoxO3","volume":"150","author":"Yang","year":"2021","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.virusres.2022.198887_bib0034","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.virol.2018.10.015","article-title":"Neuronal transcriptomic responses to Japanese encephalitis virus infection with a special focus on chemokine CXCL11 and pattern recognition receptors RIG-1 and MDA5","volume":"527","author":"Yu","year":"2019","journal-title":"Virology"},{"issue":"8","key":"10.1016\/j.virusres.2022.198887_bib0035","doi-asserted-by":"crossref","first-page":"12775","DOI":"10.1002\/jcb.28545","article-title":"miR-193b-5p regulates chondrocytes metabolism by directly targeting histone deacetylase 7 in interleukin-1\u03b2-induced osteoarthritis","volume":"120","author":"Zhang","year":"2019","journal-title":"J. Cell. Biochem."},{"issue":"1","key":"10.1016\/j.virusres.2022.198887_bib0036","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3390\/v9010005","article-title":"Mx is not responsible for the antiviral activity of interferon-\u03b1 against Japanese Encephalitis Virus","volume":"9","author":"Zhou","year":"2017","journal-title":"Viruses"}],"container-title":["Virus Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170222002155?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170222002155?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T14:17:50Z","timestamp":1759155470000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168170222002155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":36,"alternative-id":["S0168170222002155"],"URL":"https:\/\/doi.org\/10.1016\/j.virusres.2022.198887","relation":{},"ISSN":["0168-1702"],"issn-type":[{"type":"print","value":"0168-1702"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Novel insights into host responses to Japanese Encephalitis Virus infection: Reanalysis of public transcriptome and microRNAome datasets","name":"articletitle","label":"Article Title"},{"value":"Virus Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virusres.2022.198887","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"198887"}}