{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:08:01Z","timestamp":1790759281039,"version":"4.1.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T00:00:00Z","timestamp":1668556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003345","name":"Chinese Academy of Meteorological Sciences","doi-asserted-by":"publisher","award":["2021-I2M-1-038"],"award-info":[{"award-number":["2021-I2M-1-038"]}],"id":[{"id":"10.13039\/501100003345","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virus Research"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.virusres.2022.199004","type":"journal-article","created":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T00:13:44Z","timestamp":1668644024000},"page":"199004","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["An atlas of the blood virome in healthy individuals"],"prefix":"10.1016","volume":"323","author":[{"given":"Bo","family":"Feng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3799-5526","authenticated-orcid":false,"given":"Yongfeng","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.virusres.2022.199004_bib0001","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jcv.2004.09.022","article-title":"Simultaneous detection of herpes simplex virus types 1 and 2 by real-time PCR and Pyrosequencing","volume":"33","author":"Adelson","year":"2005","journal-title":"J. Clin. Virol."},{"issue":"6","key":"10.1016\/j.virusres.2022.199004_bib33","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1099\/0022-1317-81-6-1507","article-title":"Complete sequence determination and genetic analysis of Banna virus and Kadipiro virus: proposal for assignment to a new genus (Seadornavirus) within the family Reoviridae","volume":"81","author":"Attoui","year":"2000","journal-title":"J. Gen. Virol."},{"issue":"6378","key":"10.1016\/j.virusres.2022.199004_bib0002","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1126\/science.aap7463","article-title":"The global virome project","volume":"359","author":"Carroll","year":"2018","journal-title":"Science"},{"issue":"11","key":"10.1016\/j.virusres.2022.199004_bib0003","doi-asserted-by":"crossref","DOI":"10.3390\/v13112322","article-title":"Exploring the diversity of the human blood virome","volume":"13","author":"Cebria-Mendoza","year":"2021","journal-title":"Viruses"},{"issue":"10","key":"10.1016\/j.virusres.2022.199004_bib0004","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1002\/jmv.21592","article-title":"Human papillomavirus DNA detected in peripheral blood samples from healthy Australian male blood donors","volume":"81","author":"Chen","year":"2009","journal-title":"J. Med. Virol."},{"issue":"1","key":"10.1016\/j.virusres.2022.199004_bib0005","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1080\/22221751.2019.1603791","article-title":"Detection of dicistroviruses RNA in blood of febrile Tanzanian children","volume":"8","author":"Cordey","year":"2019","journal-title":"Emerg. Microbes Infect."},{"issue":"5","key":"10.1016\/j.virusres.2022.199004_bib0006","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/j.cell.2013.10.034","article-title":"Temporal response of the human virome to immunosuppression and antiviral therapy","volume":"155","author":"De Vlaminck","year":"2013","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.virusres.2022.199004_bib0007","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/s12915-019-0704-y","article-title":"Studying the gut virome in the metagenomic era: challenges and perspectives","volume":"17","author":"Garmaeva","year":"2019","journal-title":"BMC Biol."},{"issue":"3","key":"10.1016\/j.virusres.2022.199004_bib0008","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1574-695X.2006.00044.x","article-title":"Bacteriophage translocation","volume":"46","author":"Gorski","year":"2006","journal-title":"FEMS Immunol. Med. Microbiol."},{"issue":"7","key":"10.1016\/j.virusres.2022.199004_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmi.2015.03.006","article-title":"Serial high-resolution analysis of blood virome and host cytokines expression profile of a patient with fatal H7N9 infection by massively parallel RNA sequencing","volume":"21","author":"Hu","year":"2015","journal-title":"Clin. Microbiol. Infect."},{"issue":"1","key":"10.1016\/j.virusres.2022.199004_bib0010","doi-asserted-by":"crossref","first-page":"6909","DOI":"10.1038\/s41467-021-26980-8","article-title":"Plasma virome and the risk of blood-borne infection in persons with substance use disorder","volume":"12","author":"Kandathil","year":"2021","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.virusres.2022.199004_bib0011","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01466-15","article-title":"Virome analysis of transfusion recipients reveals a novel human virus that shares genomic features with hepaciviruses and pegiviruses","volume":"6","author":"Kapoor","year":"2015","journal-title":"mBio"},{"key":"10.1016\/j.virusres.2022.199004_bib0012","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.coviro.2021.02.002","article-title":"The healthy human virome: from virus-host symbiosis to disease","volume":"47","author":"Koonin","year":"2021","journal-title":"Curr. Opin. Virol."},{"issue":"3-4","key":"10.1016\/j.virusres.2022.199004_bib0013","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/j.1399-3062.2005.00106.x","article-title":"Retrospective analysis of varicella zoster virus (VZV) copy DNA numbers in plasma of immunocompetent patients with herpes zoster, of immunocompromised patients with disseminated VZV disease, and of asymptomatic solid organ transplant recipients","volume":"7","author":"Kronenberg","year":"2005","journal-title":"Transpl. Infect. Dis."},{"issue":"1","key":"10.1016\/j.virusres.2022.199004_bib0014","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12915-020-00785-5","article-title":"A tissue level atlas of the healthy human virome","volume":"18","author":"Kumata","year":"2020","journal-title":"BMC Biol."},{"issue":"6","key":"10.1016\/j.virusres.2022.199004_bib31","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.3390\/v13061073","article-title":"Full-Genome Sequences of Alphacoronaviruses and Astroviruses from Myotis and Pipistrelle Bats in Denmark","volume":"13","author":"Lazov","year":"2021","journal-title":"Viruses"},{"issue":"10","key":"10.1016\/j.virusres.2022.199004_bib0015","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.1111\/trf.15476","article-title":"Full annotation of serum virome in Chinese blood donors with elevated alanine aminotransferase levels","volume":"59","author":"Li","year":"2019","journal-title":"Transfusion"},{"issue":"8","key":"10.1016\/j.virusres.2022.199004_bib0016","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/s41579-021-00536-5","article-title":"The human virome: assembly, composition and host interactions","volume":"19","author":"Liang","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"issue":"7809","key":"10.1016\/j.virusres.2022.199004_bib0017","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/s41586-020-2192-1","article-title":"The stepwise assembly of the neonatal virome is modulated by breastfeeding","volume":"581","author":"Liang","year":"2020","journal-title":"Nature"},{"issue":"37","key":"10.1016\/j.virusres.2022.199004_bib0018","doi-asserted-by":"crossref","first-page":"10400","DOI":"10.1073\/pnas.1601060113","article-title":"Healthy human gut phageome","volume":"113","author":"Manrique","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"3","key":"10.1016\/j.virusres.2022.199004_bib0019","article-title":"The blood DNA virome in 8000 humans","volume":"13","author":"Moustafa","year":"2017","journal-title":"PLoS Pathog."},{"issue":"12","key":"10.1016\/j.virusres.2022.199004_bib30","doi-asserted-by":"crossref","first-page":"3359","DOI":"10.1099\/jgv.0.000644","article-title":"The plasma virome of febrile adult Kenyans shows frequent parvovirus B19 infections and a novel arbovirus (Kadipiro virus)","volume":"97","author":"Ngoi","year":"2016","journal-title":"J. Gen. Virol."},{"issue":"3","key":"10.1016\/j.virusres.2022.199004_bib32","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1099\/jgv.0.000762","article-title":"Corrigendum: The plasma virome of febrile adult Kenyans shows frequent parvovirus B19 infections and a novel arbovirus (Kadipiro virus)","volume":"98","author":"Ngoi","year":"2017","journal-title":"J. Gen. Virol."},{"issue":"26","key":"10.1016\/j.virusres.2022.199004_bib0020","doi-asserted-by":"crossref","first-page":"7099","DOI":"10.1182\/blood-2010-09-310557","article-title":"Merkel cell polyomavirus DNA sequences in the buffy coats of healthy blood donors","volume":"117","author":"Pancaldi","year":"2011","journal-title":"Blood"},{"issue":"9","key":"10.1016\/j.virusres.2022.199004_bib0021","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1000578","article-title":"Quantitation of human seroresponsiveness to Merkel cell polyomavirus","volume":"5","author":"Pastrana","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virusres.2022.199004_bib0022","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1146\/annurev-micro-102215-095431","article-title":"Metagenomics and the human virome in asymptomatic individuals","volume":"70","author":"Rascovan","year":"2016","journal-title":"Annu. Rev. Microbiol."},{"issue":"30","key":"10.1016\/j.virusres.2022.199004_bib0023","doi-asserted-by":"crossref","first-page":"4725","DOI":"10.3748\/wjg.14.4725","article-title":"Hepatitis G virus","volume":"14","author":"Reshetnyak","year":"2008","journal-title":"World J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.virusres.2022.199004_bib0024","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12985-022-01769-3","article-title":"Clinical and molecular aspects of human pegiviruses in the interaction host and infectious agent","volume":"19","author":"Samadi","year":"2022","journal-title":"Virol. J."},{"issue":"3","key":"10.1016\/j.virusres.2022.199004_bib0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003631","article-title":"Discovery of novel rhabdoviruses in the blood of healthy individuals from West Africa","volume":"9","author":"Stremlau","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"3","key":"10.1016\/j.virusres.2022.199004_bib29","first-page":"173","article-title":"The first report of Kadipiro virus isolation in China","volume":"25","author":"Sun","year":"2009","journal-title":"Bing Du Xue Bao."},{"issue":"1","key":"10.1016\/j.virusres.2022.199004_bib0026","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.cell.2014.02.032","article-title":"The virome in mammalian physiology and disease","volume":"157","author":"Virgin","year":"2014","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.virusres.2022.199004_bib28","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s12985-018-0966-y","article-title":"Identification and genetic analysis of Kadipiro virus isolated in Shandong province, China","volume":"15","author":"Zhang","year":"2018","journal-title":"Virol. J."},{"key":"10.1016\/j.virusres.2022.199004_bib0027","doi-asserted-by":"crossref","DOI":"10.1177\/17590914211053505","article-title":"Simultaneous detection of herpes simplex virus type 1 latent and lytic transcripts in brain tissue","volume":"14","author":"Zhang","year":"2022","journal-title":"ASN Neuro"}],"container-title":["Virus Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170222003331?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168170222003331?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T14:22:17Z","timestamp":1759155737000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168170222003331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":33,"alternative-id":["S0168170222003331"],"URL":"https:\/\/doi.org\/10.1016\/j.virusres.2022.199004","relation":{},"ISSN":["0168-1702"],"issn-type":[{"value":"0168-1702","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An atlas of the blood virome in healthy individuals","name":"articletitle","label":"Article Title"},{"value":"Virus Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virusres.2022.199004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"199004"}}