{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:04:33Z","timestamp":1762160673201,"version":"3.33.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,18]],"date-time":"2013-07-18T00:00:00Z","timestamp":1374105600000},"content-version":"vor","delay-in-days":1994,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vision Research"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1016\/j.visres.2007.07.009","type":"journal-article","created":{"date-parts":[[2007,9,4]],"date-time":"2007-09-04T12:42:51Z","timestamp":1188909771000},"page":"325-331","source":"Crossref","is-referenced-by-count":22,"title":["Retinal degeneration in children: Dark adapted visual threshold and arteriolar diameter"],"prefix":"10.1016","volume":"48","author":[{"given":"Ronald M.","family":"Hansen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan E.","family":"Eklund","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilan Y.","family":"Benador","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie A.","family":"Mocko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James D.","family":"Akula","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Elena","family":"Martinez-Perez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne B.","family":"Fulton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.visres.2007.07.009_bib1","first-page":"1446","article-title":"Acuity-luminance and foveal increment threshold functions in retinitis pigmentosa","volume":"32","author":"Alexander","year":"1991","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"3","key":"10.1016\/j.visres.2007.07.009_bib2","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/0002-9394(85)90351-4","article-title":"Natural course of retinitis pigmentosa over a three-year interval","volume":"99","author":"Berson","year":"1985","journal-title":"American Journal of Ophthalmology"},{"issue":"3","key":"10.1016\/j.visres.2007.07.009_bib3","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1167\/iovs.06-0978","article-title":"Distribution and associations of retinal vascular caliber with ethnicity, gender, and birth parameters in young children","volume":"48","author":"Cheung","year":"2007","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"6","key":"10.1016\/j.visres.2007.07.009_bib4","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1097\/00006982-200509000-00014","article-title":"Outcome measures and their application in clinical trials for retinal degenerative diseases: Outline, review, and perspective","volume":"25","author":"Fishman","year":"2005","journal-title":"Retina"},{"key":"10.1016\/j.visres.2007.07.009_bib5","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3109\/13816818309007807","article-title":"Retinal adaptation in infants and children with retinal degenerations","volume":"2","author":"Fulton","year":"1983","journal-title":"Ophthalmic Paediatrics and Genetics"},{"issue":"1","key":"10.1016\/j.visres.2007.07.009_bib6","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0166-4328(83)90151-1","article-title":"Retinal sensitivity and adaptation in pediatric patients","volume":"10","author":"Fulton","year":"1983","journal-title":"Behavioral Brain Research"},{"key":"10.1016\/j.visres.2007.07.009_bib7","series-title":"Principles and practice of clinical electrophysiology of vision","first-page":"281","article-title":"Testing pediatric patients","author":"Fulton","year":"1991"},{"issue":"6","key":"10.1016\/j.visres.2007.07.009_bib8","first-page":"1588","article-title":"The development of scotopic sensitivity","volume":"41","author":"Fulton","year":"2000","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"11","key":"10.1016\/j.visres.2007.07.009_bib9","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1001\/archopht.1993.01090110066026","article-title":"Natural course of visual functions in the Bardet-Biedl syndrome","volume":"111","author":"Fulton","year":"1993","journal-title":"Archives of Ophthalmology"},{"issue":"6","key":"10.1016\/j.visres.2007.07.009_bib10","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1001\/archopht.1996.01100130690009","article-title":"Vision in Leber congenital amaurosis","volume":"114","author":"Fulton","year":"1996","journal-title":"Archives of Ophthalmology"},{"issue":"7","key":"10.1016\/j.visres.2007.07.009_bib11","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1097\/00006982-200510000-00016","article-title":"Evaluation of genotype\u2013phenotype associations in Leber congenital amaurosis","volume":"25","author":"Galvin","year":"2005","journal-title":"Retina"},{"issue":"12","key":"10.1016\/j.visres.2007.07.009_bib12","doi-asserted-by":"crossref","first-page":"4734","DOI":"10.1167\/iovs.05-0646","article-title":"Diagnosis of plus disease in retinopathy of prematurity using Retinal Image multiScale Analysis","volume":"46","author":"Gelman","year":"2005","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"4","key":"10.1016\/j.visres.2007.07.009_bib13","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/S0002-9394(14)72109-9","article-title":"Retinal hemodynamics in retinitis pigmentosa","volume":"122","author":"Grunwald","year":"1996","journal-title":"American Journal of Ophthalmology"},{"issue":"3","key":"10.1016\/j.visres.2007.07.009_bib14","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1017\/S0952523800008415","article-title":"Dark adapted thresholds at 10- and 30-deg eccentricities in 10-week-old infants","volume":"12","author":"Hansen","year":"1995","journal-title":"Visual Neuroscience"},{"issue":"5","key":"10.1016\/j.visres.2007.07.009_bib15","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/0042-6989(86)90092-1","article-title":"Background adaptation in human infants","volume":"26","author":"Hansen","year":"1986","journal-title":"Vision Research"},{"issue":"8","key":"10.1016\/j.visres.2007.07.009_bib16","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1097\/00006324-199908000-00022","article-title":"Glaucoma screening: The importance of combining test data","volume":"76","author":"Harper","year":"1999","journal-title":"Optometry and Vision Science"},{"issue":"3","key":"10.1016\/j.visres.2007.07.009_bib17","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1034\/j.1600-0420.1998.760302.x","article-title":"Optic disc size and retinal vessel characteristics in healthy children","volume":"76","author":"Hellstrom","year":"1998","journal-title":"Acta Ophthalmologica Scandinavica"},{"issue":"1","key":"10.1016\/j.visres.2007.07.009_bib18","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0042-6989(90)90127-7","article-title":"Models of the normal and abnormal rod system","volume":"30","author":"Hood","year":"1990","journal-title":"Vision Research"},{"issue":"7","key":"10.1016\/j.visres.2007.07.009_bib19","first-page":"1898","article-title":"Disease expression of RP1 mutations causing autosomal dominant retinitis pigmentosa","volume":"41","author":"Jacobson","year":"2000","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"2","key":"10.1016\/j.visres.2007.07.009_bib20","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.exer.2005.03.006","article-title":"Retinal remodeling during retinal degeneration","volume":"81","author":"Jones","year":"2005","journal-title":"Experimental Eye Research"},{"issue":"Spec No 1","key":"10.1016\/j.visres.2007.07.009_bib21","doi-asserted-by":"crossref","first-page":"R65","DOI":"10.1093\/hmg\/ddh092","article-title":"The oligogenic properties of Bardet-Biedl syndrome","volume":"13","author":"Katsanis","year":"2004","journal-title":"Human Molecular Genetics"},{"issue":"4","key":"10.1016\/j.visres.2007.07.009_bib22","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.survophthal.2004.04.003","article-title":"An overview of Leber congenital amaurosis: A model to understand human retinal development","volume":"49","author":"Koenekoop","year":"2004","journal-title":"Survey of Ophthalmology"},{"issue":"Spec No 2","key":"10.1016\/j.visres.2007.07.009_bib23","doi-asserted-by":"crossref","first-page":"R262","DOI":"10.1093\/hmg\/ddl205","article-title":"Usher syndrome: Molecular links of pathogenesis, proteins and pathways","volume":"15","author":"Kremer","year":"2006","journal-title":"Human Molecular Genetics"},{"issue":"3","key":"10.1016\/j.visres.2007.07.009_bib24","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1001\/archopht.119.3.415","article-title":"Mutations in the CRB1 gene cause Leber congenital amaurosis","volume":"119","author":"Lotery","year":"2001","journal-title":"Archives of Ophthalmology"},{"key":"10.1016\/j.visres.2007.07.009_bib25","unstructured":"Lu, M., Hansen, R.M., Cunningham, M.J., Eklund, S.E., & Fulton, A.B. (in press). Effects of Desferoxamine (DFO) on Retinal and Visual Function. Archives of Ophthalmology."},{"key":"10.1016\/j.visres.2007.07.009_bib26","series-title":"Department of Biological and Medical Systems","first-page":"195","article-title":"Computer analysis of the geometry of the retinal vasculature","author":"Martinez-Perez","year":"2001"},{"issue":"8","key":"10.1016\/j.visres.2007.07.009_bib27","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1109\/TBME.2002.800789","article-title":"Retinal vascular tree morphology: A semi-automatic quantification","volume":"49","author":"Martinez-Perez","year":"2002","journal-title":"IEEE Transactions on Biomedical Engineering"},{"issue":"1","key":"10.1016\/j.visres.2007.07.009_bib28","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.media.2006.11.004","article-title":"Segmentation of blood vessels from red-free and fluorescein retinal images","volume":"11","author":"Martinez-Perez","year":"2007","journal-title":"Medical Image Analysis"},{"issue":"6","key":"10.1016\/j.visres.2007.07.009_bib29","doi-asserted-by":"crossref","first-page":"3088","DOI":"10.1073\/pnas.95.6.3088","article-title":"Mutations in the RPE65 gene in patients with autosomal recessive retinitis pigmentosa or leber congenital amaurosis","volume":"95","author":"Morimura","year":"1998","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"4","key":"10.1016\/j.visres.2007.07.009_bib30","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/ng935","article-title":"Identification of the gene (BBS1) most commonly involved in Bardet-Biedl syndrome, a complex human obesity syndrome","volume":"31","author":"Mykytyn","year":"2002","journal-title":"Nature Genetics"},{"issue":"8","key":"10.1016\/j.visres.2007.07.009_bib31","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1093\/hmg\/10.8.865","article-title":"Positional cloning of a novel gene on chromosome 16q causing Bardet-Biedl syndrome (BBS2)","volume":"10","author":"Nishimura","year":"2001","journal-title":"Human Molecular Genetics"},{"issue":"12","key":"10.1016\/j.visres.2007.07.009_bib32","first-page":"4007","article-title":"Ambient hypoxia reverses retinal vascular attenuation in a transgenic mouse model of autosomal dominant retinitis pigmentosa","volume":"41","author":"Penn","year":"2000","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"1","key":"10.1016\/j.visres.2007.07.009_bib33","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.exer.2005.11.010","article-title":"Molecular basis of human Usher syndrome: Deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease","volume":"83","author":"Reiners","year":"2006","journal-title":"Experimental Eye Research"},{"issue":"2","key":"10.1016\/j.visres.2007.07.009_bib34","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.exer.2004.09.008","article-title":"Quantifying rod photoreceptor-mediated vision in retinal degenerations: Dark adapted thresholds as outcome measures","volume":"80","author":"Roman","year":"2005","journal-title":"Experimental Eye Research"},{"issue":"12","key":"10.1016\/j.visres.2007.07.009_bib35","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1016\/0042-6989(84)90006-3","article-title":"Area-threshold relations at controlled retinal locations in 1-month-old infants","volume":"24","author":"Schneck","year":"1984","journal-title":"Vision Research"},{"issue":"8","key":"10.1016\/j.visres.2007.07.009_bib36","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1167\/iovs.03-1208","article-title":"Fundus autofluorescence in patients with Leber congenital amaurosis","volume":"45","author":"Scholl","year":"2004","journal-title":"Investigative Ophthalmology and Visual Science"},{"key":"10.1016\/j.visres.2007.07.009_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.2044-8317.1965.tb00689.x","article-title":"Sequential Estimation of Points on a Psychometric Function","volume":"18","author":"Wetherill","year":"1965","journal-title":"British Journal of Mathematical and Statistical Psychology"},{"key":"10.1016\/j.visres.2007.07.009_bib38","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1080\/00031305.1986.10475378","article-title":"Prediction limits for a univariate normal observation","volume":"40","author":"Whitmore","year":"1986","journal-title":"The American Statistician"}],"container-title":["Vision Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042698907003136?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042698907003136?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T20:45:53Z","timestamp":1737405953000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042698907003136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["S0042698907003136"],"URL":"https:\/\/doi.org\/10.1016\/j.visres.2007.07.009","relation":{},"ISSN":["0042-6989"],"issn-type":[{"type":"print","value":"0042-6989"}],"subject":[],"published":{"date-parts":[[2008,2]]}}}