{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T23:47:21Z","timestamp":1768693641363,"version":"3.49.0"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:00:00Z","timestamp":1755216000000},"content-version":"am","delay-in-days":318,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100008893","name":"University of Iowa","doi-asserted-by":"publisher","award":["P30EY025580"],"award-info":[{"award-number":["P30EY025580"]}],"id":[{"id":"10.13039\/100008893","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"NEI","doi-asserted-by":"publisher","award":["R21EY029991"],"award-info":[{"award-number":["R21EY029991"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"NEI","doi-asserted-by":"publisher","award":["R01EY035679"],"award-info":[{"award-number":["R01EY035679"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002924","name":"Glaucoma Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002924","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vision Research"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.visres.2024.108464","type":"journal-article","created":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T06:59:31Z","timestamp":1723705171000},"page":"108464","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Minimal phenotypes in transgenic mice with the human LOXL1\/LOXL1-AS1 locus associated with exfoliation glaucoma"],"prefix":"10.1016","volume":"223","author":[{"given":"Kacie J.","family":"Meyer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah E.","family":"Mercer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben R.","family":"Roos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John H.","family":"Fingert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael G.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.visres.2024.108464_b0005","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.exer.2016.11.011","article-title":"Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology","volume":"154","author":"Aboobakar","year":"2017","journal-title":"Experimental Eye Research"},{"issue":"1","key":"10.1016\/j.visres.2024.108464_b0010","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/s12920-022-01216-w","article-title":"The landscape of GWAS validation; systematic review identifying 309 validated non-coding variants across 130 human diseases","volume":"15","author":"Alsheikh","year":"2022","journal-title":"BMC Medical Genomics"},{"key":"10.1016\/j.visres.2024.108464_b0015","unstructured":"Anderson, M.G. (2024). DIAMOND: The Database of Iowa Animal Models for Ophthalmic and Neurologic Disease. Dataset 2: Slit-lamp images for transgenic mice with the human LOXL1\/LOXL1-AS1 locus associated with exfoliation glaucoma. DOI: 10.25820\/data.007304. University of Iowa."},{"issue":"Suppl 1","key":"10.1016\/j.visres.2024.108464_b0020","doi-asserted-by":"crossref","first-page":"S78","DOI":"10.1097\/IJG.0000000000000911","article-title":"Update on Animal Models of Exfoliation Syndrome","volume":"27","author":"Anderson","year":"2018","journal-title":"Journal of Glaucoma"},{"issue":"Suppl 1","key":"10.1016\/j.visres.2024.108464_b0025","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1097\/IJG.0000000000000928","article-title":"Genetics of Exfoliation Syndrome","volume":"27","author":"Aung","year":"2018","journal-title":"Journal of Glaucoma"},{"issue":"7","key":"10.1016\/j.visres.2024.108464_b0030","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1038\/ng.3875","article-title":"Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci","volume":"49","author":"Aung","year":"2017","journal-title":"Nature Genetics"},{"issue":"15","key":"10.1016\/j.visres.2024.108464_b0035","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1093\/hmg\/ddz075","article-title":"The protective variant rs7173049 at LOXL1 locus impacts on retinoic acid signaling pathway in pseudoexfoliation syndrome","volume":"28","author":"Berner","year":"2019","journal-title":"Human Molecular Genetics"},{"issue":"Suppl 1","key":"10.1016\/j.visres.2024.108464_b0040","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.1097\/IJG.0000000000000919","article-title":"Exfoliation Syndrome: A Disease of Autophagy and LOXL1 Proteopathy","volume":"27","author":"Bernstein","year":"2018","journal-title":"Journal of Glaucoma"},{"issue":"12","key":"10.1016\/j.visres.2024.108464_b0045","doi-asserted-by":"crossref","DOI":"10.3390\/cells10123448","article-title":"Primary Human Trabecular Meshwork Model for Pseudoexfoliation","volume":"10","author":"Chakraborty","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.visres.2024.108464_b0050","first-page":"146","article-title":"Analysis of LOXL1 polymorphisms in a United States population with pseudoexfoliation glaucoma","volume":"14","author":"Challa","year":"2008","journal-title":"Molecular Vision"},{"issue":"1","key":"10.1016\/j.visres.2024.108464_b0055","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1038\/s41467-017-00837-5","article-title":"Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility","volume":"8","author":"Chintalapudi","year":"2017","journal-title":"Nature Communications"},{"issue":"1","key":"10.1016\/j.visres.2024.108464_b0060","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1038\/s41467-018-04555-4","article-title":"A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci","volume":"9","author":"Choquet","year":"2018","journal-title":"Nature Communications"},{"key":"10.1016\/j.visres.2024.108464_b0065","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1471-2350-9-5","article-title":"DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity","volume":"9","author":"Fan","year":"2008","journal-title":"BMC Medical Genetics"},{"issue":"6","key":"10.1016\/j.visres.2024.108464_b0070","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/j.ajo.2007.09.034","article-title":"LOXL1 mutations are associated with exfoliation syndrome in patients from the midwestern United States","volume":"144","author":"Fingert","year":"2007","journal-title":"American Journal of Ophthalmology"},{"issue":"7","key":"10.1016\/j.visres.2024.108464_b0075","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1097\/IJG.0b013e318255da16","article-title":"Circumferential iris transillumination defects in exfoliation syndrome","volume":"22","author":"Fingert","year":"2013","journal-title":"Journal of Glaucoma"},{"issue":"1","key":"10.1016\/j.visres.2024.108464_b0080","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s10238-024-01355-7","article-title":"Long non-coding RNA LOXL1-AS1: A potential biomarker and therapeutic target in human malignant tumors","volume":"24","author":"Fu","year":"2024","journal-title":"Clinical and Experimental Medicine"},{"issue":"2","key":"10.1016\/j.visres.2024.108464_b0085","doi-asserted-by":"crossref","first-page":"e9050","DOI":"10.1371\/journal.pone.0009050","article-title":"VAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humans","volume":"5","author":"Fujikawa","year":"2010","journal-title":"PLoS One1"},{"issue":"4","key":"10.1016\/j.visres.2024.108464_b0090","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.ajpath.2015.11.026","article-title":"Mice Homozygous for a Deletion in the Glaucoma Susceptibility Locus INK4 Show Increased Vulnerability of Retinal Ganglion Cells to Elevated Intraocular Pressure","volume":"186","author":"Gao","year":"2016","journal-title":"The American Journal of Pathology"},{"issue":"2","key":"10.1016\/j.visres.2024.108464_b0095","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/aos.14298","article-title":"Recent advances in risk factors associated with ocular exfoliation syndrome","volume":"98","author":"Ghaffari Sharaf","year":"2020","journal-title":"Acta Ophthalmologica"},{"key":"10.1016\/j.visres.2024.108464_b0100","first-page":"2381","article-title":"Evaluation of LOXL1 polymorphisms in primary open-angle glaucoma in southern and northern Chinese","volume":"14","author":"Gong","year":"2008","journal-title":"Molecular Vision"},{"issue":"4","key":"10.1016\/j.visres.2024.108464_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.xops.2024.100504","article-title":"Deep Learning-Based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell Morphology","volume":"4","author":"Greatbatch","year":"2024","journal-title":"Ophthalmol Sci"},{"key":"10.1016\/j.visres.2024.108464_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2020.107975","article-title":"Lysyl Oxidase Like 1: Biological roles and regulation","volume":"193","author":"Greene","year":"2020","journal-title":"Experimental Eye Research"},{"issue":"1","key":"10.1016\/j.visres.2024.108464_b0115","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/s41467-023-44380-y","article-title":"Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma","volume":"15","author":"Hamel","year":"2024","journal-title":"Nature Communications"},{"issue":"7","key":"10.1016\/j.visres.2024.108464_b0120","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1038\/s41588-023-01428-5","article-title":"Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci","volume":"55","author":"Han","year":"2023","journal-title":"Nature Genetics"},{"issue":"22","key":"10.1016\/j.visres.2024.108464_b0125","doi-asserted-by":"crossref","first-page":"6552","DOI":"10.1093\/hmg\/ddv347","article-title":"Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus","volume":"24","author":"Hauser","year":"2015","journal-title":"Human Molecular Genetics"},{"issue":"3","key":"10.1016\/j.visres.2024.108464_b0130","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.ajo.2007.10.023","article-title":"Lysyl oxidase-like 1 polymorphisms and exfoliation syndrome in the Japanese population","volume":"145","author":"Hayashi","year":"2008","journal-title":"American Journal of Ophthalmology"},{"issue":"9","key":"10.1016\/j.visres.2024.108464_b0135","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1167\/tvst.11.9.17","article-title":"Biological Correlations and Confounders for Quantification of Retinal Ganglion Cells by Optical Coherence Tomography Based on Studies of Outbred Mice","volume":"11","author":"Hedberg-Buenz","year":"2022","journal-title":"Translational Vision Science & Technology"},{"issue":"8 Suppl 1","key":"10.1016\/j.visres.2024.108464_b0140","doi-asserted-by":"crossref","first-page":"S68","DOI":"10.1097\/IJG.0000000000000121","article-title":"Animal models of exfoliation syndrome, now and future","volume":"23","author":"John","year":"2014","journal-title":"Journal of Glaucoma"},{"issue":"1","key":"10.1016\/j.visres.2024.108464_b0145","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.ophtha.2011.06.018","article-title":"Demographic and geographic features of exfoliation glaucoma in 2 United States-based prospective cohorts","volume":"119","author":"Kang","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.visres.2024.108464_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2023.101214","article-title":"Current understanding of genetics and epigenetics in pseudoexfoliation syndrome and glaucoma","volume":"94","author":"Kapuganti","year":"2023","journal-title":"Molecular Aspects of Medicine"},{"issue":"3","key":"10.1016\/j.visres.2024.108464_b0155","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1097\/00061198-200306000-00002","article-title":"Estimated incidence of pseudoexfoliation syndrome and pseudoexfoliation glaucoma in Olmsted County, Minnesota","volume":"12","author":"Karger","year":"2003","journal-title":"Journal of Glaucoma"},{"issue":"1","key":"10.1016\/j.visres.2024.108464_b0160","doi-asserted-by":"crossref","first-page":"e1007145","DOI":"10.1371\/journal.pgen.1007145","article-title":"Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma","volume":"14","author":"King","year":"2018","journal-title":"PLoS Genetics"},{"issue":"D1","key":"10.1016\/j.visres.2024.108464_b0165","doi-asserted-by":"crossref","first-page":"D126","DOI":"10.1093\/nar\/gkv1203","article-title":"ORegAnno 3.0: A community-driven resource for curated regulatory annotation","volume":"44","author":"Lesurf","year":"2016","journal-title":"Nucleic Acids Research"},{"issue":"8","key":"10.1016\/j.visres.2024.108464_b0170","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1001\/jama.2021.0507","article-title":"Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye","volume":"325","author":"Li","year":"2021","journal-title":"Journal of the American Medical Association"},{"issue":"5","key":"10.1016\/j.visres.2024.108464_b0175","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1017\/S0952523805225130","article-title":"Inherited glaucoma in DBA\/2J mice: Pertinent disease features for studying the neurodegeneration","volume":"22","author":"Libby","year":"2005","journal-title":"Visual Neuroscience"},{"issue":"2","key":"10.1016\/j.visres.2024.108464_b0180","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/ng1297","article-title":"Elastic fiber homeostasis requires lysyl oxidase-like 1 protein","volume":"36","author":"Liu","year":"2004","journal-title":"Nature Genetics"},{"issue":"5","key":"10.1016\/j.visres.2024.108464_b0185","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1167\/iovs.10-5993","article-title":"Anterior segment dysgenesis and early-onset glaucoma in nee mice with mutation of Sh3pxd2b","volume":"52","author":"Mao","year":"2011","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"10.1016\/j.visres.2024.108464_b0190","doi-asserted-by":"crossref","DOI":"10.1093\/hmg\/ddae088","article-title":"Lack of evidence for GWAS signals of exfoliation glaucoma working via monogenic loss-of-function mutation in the nearest gene","author":"Meyer","year":"2024","journal-title":"Human Molecular Genetics"},{"issue":"10","key":"10.1016\/j.visres.2024.108464_b0195","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1084\/jem.20022041","article-title":"By altering ocular immune privilege, bone marrow-derived cells pathogenically contribute to DBA\/2J pigmentary glaucoma","volume":"197","author":"Mo","year":"2003","journal-title":"The Journal of Experimental Medicine"},{"issue":"7818","key":"10.1016\/j.visres.2024.108464_b0200","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1038\/s41586-020-2493-4","article-title":"Expanded encyclopaedias of DNA elements in the human and mouse genomes","volume":"583","author":"Moore","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.visres.2024.108464_b0205","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/bs.apcsb.2021.03.004","article-title":"Proteomics of pseudoexfoliation materials in the anterior eye segment","volume":"127","author":"Morris","year":"2021","journal-title":"Advances in Protein Chemistry and Structural Biology"},{"key":"10.1016\/j.visres.2024.108464_b0210","unstructured":"Mudumbai, R., Liebmann, J.M., & Ritch, R. (1999). Combined exfoliation and pigment dispersion: an overlap syndrome. Trans Am Ophthalmol Soc, 97, 297-314; discussion 314-221."},{"issue":"1","key":"10.1016\/j.visres.2024.108464_b0215","doi-asserted-by":"crossref","first-page":"4877","DOI":"10.1038\/s41467-021-25181-7","article-title":"GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans","volume":"12","author":"Nair","year":"2021","journal-title":"Nature Communications"},{"issue":"D1","key":"10.1016\/j.visres.2024.108464_b0220","doi-asserted-by":"crossref","first-page":"D1188","DOI":"10.1093\/nar\/gkac1072","article-title":"The UCSC Genome Browser database: 2023 update","volume":"51","author":"Nassar","year":"2023","journal-title":"Nucleic Acids Research"},{"key":"10.1016\/j.visres.2024.108464_b0225","unstructured":"National Research Council Committee for the Update of the Guide for the, C., & Use of Laboratory, A. (2011). The National Academies Collection: Reports funded by National Institutes of Health. In: Guide for the Care and Use of Laboratory Animals (Washington (DC): National Academies Press (US) Copyright \u00a9 2011, National Academy of Sciences."},{"issue":"6","key":"10.1016\/j.visres.2024.108464_b0235","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/S0161-6420(00)00087-7","article-title":"Keratopathy in pseudoexfoliation syndrome as a cause of corneal endothelial decompensation: A clinicopathologic study","volume":"107","author":"Naumann","year":"2000","journal-title":"Ophthalmology"},{"issue":"10","key":"10.1016\/j.visres.2024.108464_b0240","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1136\/bjophthalmol-2017-311321","article-title":"What have we learned about exfoliation syndrome since its discovery by John Lindberg 100 years ago?","volume":"102","author":"Nazarali","year":"2018","journal-title":"The British Journal of Ophthalmology"},{"issue":"Suppl 1","key":"10.1016\/j.visres.2024.108464_b0245","doi-asserted-by":"crossref","first-page":"S83","DOI":"10.1097\/IJG.0000000000000906","article-title":"Mechanisms of Glaucoma in Exfoliation Syndrome","volume":"27","author":"Ozaki","year":"2018","journal-title":"Journal of Glaucoma"},{"issue":"6","key":"10.1016\/j.visres.2024.108464_b0250","doi-asserted-by":"crossref","first-page":"e505","DOI":"10.1111\/aos.12918","article-title":"Exfoliation syndrome: Assembling the puzzle pieces","volume":"94","author":"Pasquale","year":"2016","journal-title":"Acta Ophthalmologica"},{"issue":"1","key":"10.1016\/j.visres.2024.108464_b0255","doi-asserted-by":"crossref","first-page":"4","DOI":"10.31083\/j.fbs1601004","article-title":"Decoding Non-coding Variants: Recent Approaches to Studying Their Role in Gene Regulation and Human Diseases","volume":"16","author":"Pe\u00f1a-Mart\u00ednez","year":"2024","journal-title":"Frontiers in Bioscience (Scholar Edition)"},{"issue":"1","key":"10.1016\/j.visres.2024.108464_b0260","doi-asserted-by":"crossref","first-page":"e000803","DOI":"10.1136\/bmjophth-2021-000803","article-title":"Summary of Utah Project on Exfoliation Syndrome (UPEXS): Using a large database to identify systemic comorbidities","volume":"6","author":"Pompoco","year":"2021","journal-title":"BMJ Open Ophthalmol"},{"issue":"1","key":"10.1016\/j.visres.2024.108464_b0265","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1186\/s12967-023-04737-9","article-title":"TIE1 and TEK signalling, intraocular pressure, and primary open-angle glaucoma: A Mendelian randomization study","volume":"21","author":"Rajasundaram","year":"2023","journal-title":"Journal of Translational Medicine"},{"key":"10.1016\/j.visres.2024.108464_b0270","first-page":"318","article-title":"Association of non-synonymous single nucleotide polymorphisms in the LOXL1 gene with pseudoexfoliation syndrome in India","volume":"14","author":"Ramprasad","year":"2008","journal-title":"Molecular Vision"},{"issue":"12","key":"10.1016\/j.visres.2024.108464_b0275","doi-asserted-by":"crossref","first-page":"e113329","DOI":"10.1371\/journal.pone.0113329","article-title":"Pattern of pseudoexfoliation deposits on the lens and their clinical correlation\u2013clinical study and review of literature","volume":"9","author":"Rao","year":"2014","journal-title":"PLoS One1"},{"issue":"8 Suppl 1","key":"10.1016\/j.visres.2024.108464_b0280","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1097\/IJG.0000000000000106","article-title":"The trabecular meshwork in normal eyes and in exfoliation glaucoma","volume":"23","author":"Rasmussen","year":"2014","journal-title":"Journal of Glaucoma"},{"issue":"2","key":"10.1016\/j.visres.2024.108464_b0285","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1097\/00061198-199400320-00018","article-title":"Exfoliation syndrome-the most common identifiable cause of open-angle glaucoma","volume":"3","author":"Ritch","year":"1994","journal-title":"Journal of Glaucoma"},{"issue":"Suppl 1","key":"10.1016\/j.visres.2024.108464_b0290","doi-asserted-by":"crossref","first-page":"S67","DOI":"10.1097\/IJG.0000000000000986","article-title":"Ocular Findings in Exfoliation Syndrome","volume":"27","author":"Ritch","year":"2018","journal-title":"Journal of Glaucoma"},{"issue":"4","key":"10.1016\/j.visres.2024.108464_b0295","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0039-6257(00)00196-X","article-title":"Exfoliation syndrome","volume":"45","author":"Ritch","year":"2001","journal-title":"Survey of Ophthalmology"},{"key":"10.1016\/j.visres.2024.108464_b0300","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jprot.2013.01.008","article-title":"MALDI MS imaging analysis of apolipoprotein E and lysyl oxidase-like 1 in human lens capsules affected by pseudoexfoliation syndrome","volume":"82","author":"Ronci","year":"2013","journal-title":"Journal of Proteomics"},{"issue":"Suppl 1","key":"10.1016\/j.visres.2024.108464_b0305","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1097\/IJG.0000000000000903","article-title":"Molecular Biology of Exfoliation Syndrome","volume":"27","author":"Schl\u00f6tzer-Schrehardt","year":"2018","journal-title":"Journal of Glaucoma"},{"issue":"2","key":"10.1016\/j.visres.2024.108464_b0310","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1097\/ICU.0000000000000736","article-title":"Pseudoexfoliation syndrome and glaucoma: From genes to disease mechanisms","volume":"32","author":"Schl\u00f6tzer-Schrehardt","year":"2021","journal-title":"Current Opinion in Ophthalmology"},{"issue":"6","key":"10.1016\/j.visres.2024.108464_b0315","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.2353\/ajpath.2008.080535","article-title":"Genotype-correlated expression of lysyl oxidase-like 1 in ocular tissues of patients with pseudoexfoliation syndrome\/glaucoma and normal patients","volume":"173","author":"Schl\u00f6tzer-Schrehardt","year":"2008","journal-title":"The American Journal of Pathology"},{"key":"10.1016\/j.visres.2024.108464_b0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2019.107818","article-title":"The role of lysyl oxidase-like 1 (LOXL1) in exfoliation syndrome and glaucoma","volume":"189","author":"Schl\u00f6tzer-Schrehardt","year":"2019","journal-title":"Experimental Eye Research"},{"issue":"21","key":"10.1016\/j.visres.2024.108464_b0325","doi-asserted-by":"crossref","first-page":"3053","DOI":"10.1093\/hmg\/ddad128","article-title":"Lysyl oxidase-like 1-antisense 1 (LOXL1-AS1) lncRNA differentially regulates gene and protein expression, signaling and morphology of human ocular cells","volume":"32","author":"Schmitt","year":"2023","journal-title":"Human Molecular Genetics"},{"issue":"12","key":"10.1016\/j.visres.2024.108464_b0330","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1093\/hmg\/ddaa021","article-title":"Identification and activity of the functional complex between hnRNPL and the pseudoexfoliation syndrome-associated lncRNA, LOXL1-AS1","volume":"29","author":"Schmitt","year":"2020","journal-title":"Human Molecular Genetics"},{"issue":"11","key":"10.1016\/j.visres.2024.108464_b0335","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.050392","article-title":"Genetic background determines severity of Loxl1-mediated systemic and ocular elastosis in mice","volume":"16","author":"Suarez","year":"2023","journal-title":"Disease Models & Mechanisms"},{"issue":"4","key":"10.1016\/j.visres.2024.108464_b0340","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.21037\/tcr-23-1450","article-title":"Potential role of lncRNA LOXL1-AS1 in human cancer development: A narrative review","volume":"13","author":"Tang","year":"2024","journal-title":"Translational Cancer Research"},{"issue":"5843","key":"10.1016\/j.visres.2024.108464_b0345","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1126\/science.1146554","article-title":"Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma","volume":"317","author":"Thorleifsson","year":"2007","journal-title":"Science"},{"issue":"7","key":"10.1016\/j.visres.2024.108464_b0350","doi-asserted-by":"crossref","first-page":"e1001008","DOI":"10.1371\/journal.pgen.1001008","article-title":"Elevated oxidative membrane damage associated with genetic modifiers of Lyst-mutant phenotypes","volume":"6","author":"Trantow","year":"2010","journal-title":"PLoS Genetics"},{"key":"10.1016\/j.visres.2024.108464_b0355","unstructured":"Tuteja, S., Zeppieri, M., & Chawla, H. (2024). Pseudoexfoliation Syndrome and Glaucoma. In: StatPearls (Treasure Island (FL): StatPearls Publishing Copyright \u00a9 2024, StatPearls Publishing LLC."},{"key":"10.1016\/j.visres.2024.108464_b0365","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2022.101066","article-title":"The genetic basis for adult onset glaucoma: Recent advances and future directions","volume":"90","author":"Wang","year":"2022","journal-title":"Progress in Retinal and Eye Research"},{"key":"10.1016\/j.visres.2024.108464_b0370","doi-asserted-by":"crossref","DOI":"10.1016\/j.mbplus.2022.100120","article-title":"Lysyl oxidase-like 1 deficiency alters ultrastructural and biomechanical properties of the peripapillary sclera in mice","volume":"16","author":"Wareham","year":"2022","journal-title":"Matrix Biol Plus"},{"issue":"2","key":"10.1016\/j.visres.2024.108464_b0375","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/FJC.0000000000000853","article-title":"LOXL1-AS1\/miR-515-5p\/STAT3 Positive Feedback Loop Facilitates Cell Proliferation and Migration in Atherosclerosis","volume":"76","author":"Xie","year":"2020","journal-title":"Journal of Cardiovascular Pharmacology"},{"issue":"4","key":"10.1016\/j.visres.2024.108464_b0380","doi-asserted-by":"crossref","first-page":"247","DOI":"10.4274\/tjo.galenos.2023.76300","article-title":"Pseudoexfoliation Glaucoma: Clinical Presentation and Therapeutic Options","volume":"53","author":"Y\u00fcksel","year":"2023","journal-title":"Turk J Ophthalmol"},{"key":"10.1016\/j.visres.2024.108464_b0385","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.exer.2018.11.001","article-title":"Transgenic lysyl oxidase homolog 1 overexpression in the mouse eye results in the formation and release of protein aggregates","volume":"179","author":"Zadravec","year":"2019","journal-title":"Experimental Eye Research"},{"issue":"8 Suppl 1","key":"10.1016\/j.visres.2024.108464_b0390","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1097\/IJG.0000000000000120","article-title":"Expression and regulation of LOXL1 and elastin-related genes in eyes with exfoliation syndrome","volume":"23","author":"Zenkel","year":"2014","journal-title":"Journal of Glaucoma"}],"container-title":["Vision Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042698924001081?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042698924001081?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T21:19:57Z","timestamp":1727385597000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042698924001081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":76,"alternative-id":["S0042698924001081"],"URL":"https:\/\/doi.org\/10.1016\/j.visres.2024.108464","relation":{},"ISSN":["0042-6989"],"issn-type":[{"value":"0042-6989","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Minimal phenotypes in transgenic mice with the human LOXL1\/LOXL1-AS1 locus associated with exfoliation glaucoma","name":"articletitle","label":"Article Title"},{"value":"Vision Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.visres.2024.108464","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108464"}}