{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T17:55:51Z","timestamp":1768586151207,"version":"3.49.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006537","name":"Vanderbilt University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006537","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022833","name":"Rajiv Gandhi Centre for Biotechnology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100022833","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vision Research"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.visres.2024.108534","type":"journal-article","created":{"date-parts":[[2024,12,25]],"date-time":"2024-12-25T00:06:17Z","timestamp":1735085177000},"page":"108534","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Functional genomics of primary congenital glaucoma by pathway analysis and functional characterization of CYP1B1 mutations"],"prefix":"10.1016","volume":"227","author":[{"given":"Muneeb A.","family":"Faiq","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Himanshu N.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mashooq","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rima","family":"Dada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin C.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanuj","family":"Dada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daman","family":"Saluja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.visres.2024.108534_b0005","doi-asserted-by":"crossref","first-page":"4329","DOI":"10.1529\/biophysj.106.085498","article-title":"Disease-causing mutations in proteins: Structural analysis of the CYP1B1 mutations causing primary congenital glaucoma in humans","volume":"91","author":"Achary","year":"2006","journal-title":"Biophysical Journal"},{"key":"10.1016\/j.visres.2024.108534_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2019.100798","article-title":"Melatonin and the control of intraocular pressure","volume":"75","author":"Alkozi","year":"2020","journal-title":"Progress in Retinal and Eye Research"},{"issue":"7","key":"10.1016\/j.visres.2024.108534_b0015","article-title":"Targeted lipidomic analysis of aqueous humor reveals signaling lipid-mediated pathways in primary open-angle glaucoma","volume":"10","author":"Azbukina","year":"2021","journal-title":"Biology (Basel)"},{"issue":"4","key":"10.1016\/j.visres.2024.108534_b0020","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.sjopt.2019.10.002","article-title":"Primary congenital glaucoma: An updated review","volume":"33","author":"Badawi","year":"2019","journal-title":"Saudi J Ophthalmol."},{"issue":"2","key":"10.1016\/j.visres.2024.108534_b0025","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1042\/bj2350365","article-title":"Purification and characterization of the NADPH-cytochrome P-450 (cytochrome c) reductase from higher-plant microsomal fraction","volume":"235","author":"Benveniste","year":"1986","journal-title":"Biochemical Journal"},{"key":"10.1016\/j.visres.2024.108534_b0030","first-page":"841","article-title":"Leu432Val polymorphism in CYP1B1 as a susceptible factor towards predisposition to primary open-angle glaucoma","volume":"14","author":"Bhattacharjee","year":"2008","journal-title":"Molecular Vision"},{"issue":"2","key":"10.1016\/j.visres.2024.108534_b0035","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1006\/abbi.1995.1421","article-title":"7-HETE, 10-HETE, and 13-HETE are major products of NADPH-dependent arachidonic acid metabolism in rat liver microsomes: Analysis of their stereochemistry, and the stereochemistry of their acid-catalyzed rearrangement","volume":"321","author":"Brash","year":"1995","journal-title":"Archives of Biochemistry and Biophysics"},{"issue":"6","key":"10.1016\/j.visres.2024.108534_b0040","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1124\/dmd.106.014282","article-title":"Cyp1b1 protein in the mouse eye during development: An immunohistochemical study","volume":"35","author":"Choudhary","year":"2007","journal-title":"Drug Metabolism and Disposition"},{"issue":"8","key":"10.1016\/j.visres.2024.108534_b0045","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1097\/FPC.0b013e3282ff5a36","article-title":"Characterization of the biochemical and structural phenotypes of four CYP1B1 mutations observed in individuals with primary congenital glaucoma","volume":"18","author":"Choudhary","year":"2008","journal-title":"Pharmacogenetics and Genomics"},{"issue":"8","key":"10.1016\/j.visres.2024.108534_b0050","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1124\/dmd.32.8.840","article-title":"Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1","volume":"32","author":"Choudhary","year":"2004","journal-title":"Drug Metabolism and Disposition"},{"issue":"3","key":"10.1016\/j.visres.2024.108534_b0055","article-title":"Hypotensive effect of nanomicellar formulation of melatonin and agomelatine in a rat model: significance for glaucoma therapy","volume":"10","author":"Dal Monte","year":"2020","journal-title":"Diagnostics (Basel)"},{"issue":"1","key":"10.1016\/j.visres.2024.108534_b0060","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.exer.2005.04.016","article-title":"Immunolocalization of CYP1B1 in normal, human, fetal and adult eyes","volume":"82","author":"Doshi","year":"2006","journal-title":"Experimental Eye Research"},{"issue":"10","key":"10.1016\/j.visres.2024.108534_b0065","article-title":"A novel methodology for enhanced and consistent heterologous expression of unmodified human cytochrome P450 1B1 (CYP1B1)","volume":"9","author":"Faiq","year":"2014","journal-title":"PLoS One1"},{"issue":"3","key":"10.1016\/j.visres.2024.108534_b0070","doi-asserted-by":"crossref","first-page":"77","DOI":"10.5005\/jp-journals-10008-1189","article-title":"CYP1B1-mediated pathobiology of primary congenital glaucoma","volume":"9","author":"Faiq","year":"2015","journal-title":"Journal of Current Glaucoma Practice"},{"issue":"9","key":"10.1016\/j.visres.2024.108534_b0075","doi-asserted-by":"crossref","first-page":"893","DOI":"10.2174\/1389200216666150206130058","article-title":"CYP1B1: A unique gene with unique characteristics","volume":"15","author":"Faiq","year":"2014","journal-title":"Current Drug Metabolism"},{"issue":"1","key":"10.1016\/j.visres.2024.108534_b0080","doi-asserted-by":"crossref","first-page":"25","DOI":"10.5005\/jp-journals-10008-1133","article-title":"Molecular diagnostics and genetic counseling in primary congenital glaucoma","volume":"7","author":"Faiq","year":"2013","journal-title":"Journal of Current Glaucoma Practice"},{"issue":"2","key":"10.1016\/j.visres.2024.108534_b0085","doi-asserted-by":"crossref","first-page":"66","DOI":"10.5005\/jp-journals-10008-1140","article-title":"Genetic, biochemical and clinical insights into primary congenital glaucoma","volume":"7","author":"Faiq","year":"2013","journal-title":"Journal of Current Glaucoma Practice"},{"issue":"12","key":"10.1016\/j.visres.2024.108534_b0090","doi-asserted-by":"crossref","first-page":"10964","DOI":"10.1021\/acscatal.8b03401","article-title":"Mechanisms of Cytochrome P450-Catalyzed Oxidations","volume":"8","author":"Guengerich","year":"2018","journal-title":"ACS Catalysis"},{"issue":"1","key":"10.1016\/j.visres.2024.108534_b0095","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1124\/dmd.121.000739","article-title":"Drug Metabolism: A half-century plus of progress, continued needs, and new opportunities","volume":"51","author":"Guengerich","year":"2023","journal-title":"Drug Metabolism and Disposition"},{"issue":"6","key":"10.1016\/j.visres.2024.108534_b0100","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1124\/dmd.123.001431","article-title":"Cytochrome P450 enzymes as drug targets in human disease","volume":"52","author":"Guengerich","year":"2024","journal-title":"Drug Metabolism and Disposition"},{"issue":"15","key":"10.1016\/j.visres.2024.108534_b0105","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1002\/elps.1150181505","article-title":"SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling","volume":"18","author":"Guex","year":"1997","journal-title":"Electrophoresis"},{"issue":"Suppl 1","key":"10.1016\/j.visres.2024.108534_b0110","first-page":"S162","article-title":"Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: A historical perspective","volume":"30","author":"Guex","year":"2009","journal-title":"Electrophoresis"},{"issue":"7","key":"10.1016\/j.visres.2024.108534_b0115","first-page":"1588","article-title":"Effect of inhibitors of arachidonic acid metabolism on corneal neovascularization in the rat","volume":"30","author":"Haynes","year":"1989","journal-title":"Investigative Ophthalmology & Visual Science"},{"issue":"2","key":"10.1016\/j.visres.2024.108534_b0120","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0003-9861(75)90047-8","article-title":"Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent formation and breakdown of hydrogen peroxide during mixed function oxidation reactions in liver microsomes","volume":"171","author":"Hildebraunt","year":"1975","journal-title":"Archives of Biochemistry and Biophysics"},{"issue":"1\u20133","key":"10.1016\/j.visres.2024.108534_b0125","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0300-483X(99)00209-7","article-title":"Enhanced expression of CYP1B1 in Escherichia coli","volume":"144","author":"Jansson","year":"2000","journal-title":"Toxicology"},{"issue":"9","key":"10.1016\/j.visres.2024.108534_b0130","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1097\/00008571-200112000-00007","article-title":"Effect of two mutations of human CYP1B1, G61E and R469W, on stability and endogenous steroid substrate metabolism","volume":"11","author":"Jansson","year":"2001","journal-title":"Pharmacogenetics"},{"key":"10.1016\/j.visres.2024.108534_b0135","unstructured":"Kaur, K., Gurnani, B. (2024). Primary Congenital Glaucoma. StatPearls. Treasure Island (FL) ineligible companies. Disclosure: Bharat Gurnani declares no relevant financial relationships with ineligible companies."},{"issue":"1","key":"10.1016\/j.visres.2024.108534_b0140","doi-asserted-by":"crossref","first-page":"7","DOI":"10.4103\/0974-9233.75878","article-title":"Primary congenital glaucoma and the involvement of CYP1B1","volume":"18","author":"Kaur","year":"2011","journal-title":"Middle East African Journal of Ophthalmology"},{"issue":"2","key":"10.1016\/j.visres.2024.108534_b0145","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1136\/bjophthalmol-2020-318563","article-title":"CYP1B1 and MYOC variants in neonatal-onset versus infantile-onset primary congenital glaucoma","volume":"107","author":"Kaushik","year":"2021","journal-title":"British Journal of Ophthalmology."},{"issue":"4","key":"10.1016\/j.visres.2024.108534_b0150","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1006\/jmbi.1993.1351","article-title":"Main-chain bond lengths and bond angles in protein structures","volume":"231","author":"Laskowski","year":"1993","journal-title":"Journal of Molecular Biology"},{"issue":"4","key":"10.1016\/j.visres.2024.108534_b0155","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0263-7855(92)80074-N","article-title":"POCKET: A computer graphics method for identifying and displaying protein cavities and their surrounding amino acids","volume":"10","author":"Levitt","year":"1992","journal-title":"Journal of Molecular Graphics"},{"issue":"3","key":"10.1016\/j.visres.2024.108534_b0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellin.2024.100162","article-title":"The development and the genetic diseases of the ciliary body","volume":"3","author":"Li","year":"2024","journal-title":"Cell Insight."},{"issue":"7","key":"10.1016\/j.visres.2024.108534_b0165","first-page":"325","article-title":"Interpretation of biological and mechanical variations between the Lowry versus Bradford method for protein quantification","volume":"2","author":"Lu","year":"2010","journal-title":"North American Journal of Medical Sciences"},{"issue":"6364","key":"10.1016\/j.visres.2024.108534_b0170","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/356083a0","article-title":"Assessment of protein models with three-dimensional profiles","volume":"356","author":"Luthy","year":"1992","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.visres.2024.108534_b0175","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1006\/jmbi.1994.1334","article-title":"Satisfying hydrogen bonding potential in proteins","volume":"238","author":"McDonald","year":"1994","journal-title":"Journal of Molecular Biology"},{"issue":"7","key":"10.1016\/j.visres.2024.108534_b0180","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1093\/bioinformatics\/14.7.617","article-title":"JOY: Protein sequence-structure representation and analysis","volume":"14","author":"Mizuguchi","year":"1998","journal-title":"Bioinformatics"},{"issue":"9","key":"10.1016\/j.visres.2024.108534_b0185","article-title":"Molecular basis for involvement of CYP1B1 in MYOC upregulation and its potential implication in glaucoma pathogenesis","volume":"7","author":"Mookherjee","year":"2012","journal-title":"PLoS One1"},{"issue":"4","key":"10.1016\/j.visres.2024.108534_b0190","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1167\/iovs.03-0404","article-title":"Correlations of genotype with phenotype in Indian patients with primary congenital glaucoma","volume":"45","author":"Panicker","year":"2004","journal-title":"Investigative Ophthalmology & Visual Science"},{"issue":"5","key":"10.1016\/j.visres.2024.108534_b0195","first-page":"1358","article-title":"Identification of novel mutations causing familial primary congenital glaucoma in Indian pedigrees","volume":"43","author":"Panicker","year":"2002","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"10.1016\/j.visres.2024.108534_b0205","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.exer.2017.01.006","article-title":"Myocilin expression is regulated by retinoic acid in the trabecular meshwork-derived cellular environment","volume":"155","author":"Prat","year":"2017","journal-title":"Experimental Eye Research"},{"issue":"7","key":"10.1016\/j.visres.2024.108534_b0210","article-title":"In search of novel CYP1B1 mutations that cause primary congenital glaucoma","volume":"56","author":"Reddy","year":"2015","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"4","key":"10.1016\/j.visres.2024.108534_b0215","doi-asserted-by":"crossref","DOI":"10.3390\/ph17040441","article-title":"The therapeutic trip of melatonin eye drops: from the ocular surface to the retina","volume":"17","author":"Rusciano","year":"2024","journal-title":"Pharmaceuticals (Basel)"},{"key":"10.1016\/j.visres.2024.108534_b0220","first-page":"25","article-title":"Spectral analyses of cytochromes P450","volume":"107","author":"Schenkman","year":"1998","journal-title":"Methods in Molecular Biology"},{"issue":"7","key":"10.1016\/j.visres.2024.108534_b0225","doi-asserted-by":"crossref","DOI":"10.3390\/jcm11072048","article-title":"Geographical variability in CYP1B1 mutations in primary congenital glaucoma","volume":"11","author":"Shah","year":"2022","journal-title":"Journal of Clinical Medicine"},{"issue":"1","key":"10.1016\/j.visres.2024.108534_b0230","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1006\/abbi.1998.0808","article-title":"Recombinant human cytochrome P450 1B1 expression in Escherichia coli","volume":"357","author":"Shimada","year":"1998","journal-title":"Archives of Biochemistry and Biophysics"},{"issue":"10","key":"10.1016\/j.visres.2024.108534_b0235","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1038\/sj.eye.6702852","article-title":"Molecular and developmental mechanisms of anterior segment dysgenesis","volume":"21","author":"Sowden","year":"2007","journal-title":"Eye (London, England)"},{"issue":"4","key":"10.1016\/j.visres.2024.108534_b0240","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1093\/hmg\/6.4.641","article-title":"Identification of three different truncating mutations in cytochrome P4501B1 (CYP1B1) as the principal cause of primary congenital glaucoma (Buphthalmos) in families linked to the GLC3A locus on chromosome 2p21","volume":"6","author":"Stoilov","year":"1997","journal-title":"Human Molecular Genetics"},{"issue":"5","key":"10.1016\/j.visres.2024.108534_b0245","doi-asserted-by":"crossref","first-page":"565","DOI":"10.4103\/0301-4738.126988","article-title":"Demographic features of subjects with congenital glaucoma","volume":"62","author":"Tamcelik","year":"2014","journal-title":"Indian Journal of Ophthalmology"},{"key":"10.1016\/j.visres.2024.108534_b0250","first-page":"1200","article-title":"Mutation spectrum of CYP1B1 in North Indian congenital glaucoma patients","volume":"15","author":"Tanwar","year":"2009","journal-title":"Molecular Vision"},{"key":"10.1016\/j.visres.2024.108534_b0255","unstructured":"Tanwar, M., Dada, T., Sihota, R., Dada, R. (2009). Identification of four novel cytochrome P4501B1 mutations (p.I94X, p.H279D, p.Q340H, and p.K433K) in primary congenital glaucoma patients. Molecular Vision 15, 2926-37."},{"issue":"2","key":"10.1016\/j.visres.2024.108534_b0260","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1177\/0300985814535613","article-title":"Ultrastructural abnormalities of the trabecular meshwork extracellular matrix in Cyp1b1-deficient mice","volume":"52","author":"Teixeira","year":"2015","journal-title":"Veterinary Pathology"},{"issue":"9","key":"10.1016\/j.visres.2024.108534_b0265","doi-asserted-by":"crossref","first-page":"3119","DOI":"10.1158\/0008-5472.CAN-04-0166","article-title":"Human CYP1B1 is regulated by estradiol via estrogen receptor","volume":"64","author":"Tsuchiya","year":"2004","journal-title":"Cancer Research"},{"issue":"19","key":"10.1016\/j.visres.2024.108534_b0270","doi-asserted-by":"crossref","first-page":"10339","DOI":"10.1073\/pnas.2001250117","article-title":"Cell atlas of aqueous humor outflow pathways in eyes of humans and four model species provides insight into glaucoma pathogenesis","volume":"117","author":"van Zyl","year":"2020","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"17","key":"10.1016\/j.visres.2024.108534_b0275","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23179912","article-title":"All-trans Retinoic Acids Synergistically and Beneficially Affect In Vitro Glaucomatous Trabecular Meshwork (TM) Models Using 2D and 3D Cell Cultures of Human TM Cells","volume":"23","author":"Watanabe","year":"2022","journal-title":"International Journal of Molecular Sciences"},{"issue":"11","key":"10.1016\/j.visres.2024.108534_b0280","first-page":"1708","article-title":"Arachidonic acid metabolism in human trabecular meshwork cells","volume":"29","author":"Weinreb","year":"1988","journal-title":"Investigative Ophthalmology & Visual Science"},{"issue":"2","key":"10.1016\/j.visres.2024.108534_b0285","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1006\/abbi.1998.0654","article-title":"Characterization of the cytochrome P450 CYP2J4: Expression in rat small intestine and role in retinoic acid biotransformation from retinal","volume":"353","author":"Zhang","year":"1998","journal-title":"Archives of Biochemistry and Biophysics"},{"issue":"1","key":"10.1016\/j.visres.2024.108534_b0290","doi-asserted-by":"crossref","first-page":"60","DOI":"10.4103\/2008-322X.156116","article-title":"Cytochrome P450 1B1 and primary congenital glaucoma","volume":"10","author":"Zhao","year":"2015","journal-title":"Journal of Ophthalmic and Vision Research"},{"issue":"21","key":"10.1016\/j.visres.2024.108534_b0295","doi-asserted-by":"crossref","first-page":"4225","DOI":"10.1128\/MCB.00856-13","article-title":"Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress","volume":"33","author":"Zhao","year":"2013","journal-title":"Molecular Cell. Biology"}],"container-title":["Vision Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042698924001780?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042698924001780?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T01:16:22Z","timestamp":1738718182000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042698924001780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":58,"alternative-id":["S0042698924001780"],"URL":"https:\/\/doi.org\/10.1016\/j.visres.2024.108534","relation":{},"ISSN":["0042-6989"],"issn-type":[{"value":"0042-6989","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Functional genomics of primary congenital glaucoma by pathway analysis and functional characterization of CYP1B1 mutations","name":"articletitle","label":"Article Title"},{"value":"Vision Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.visres.2024.108534","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108534"}}