{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:36:48Z","timestamp":1759963008484},"reference-count":39,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vascular Pharmacology"],"published-print":{"date-parts":[[2004,8]]},"DOI":"10.1016\/j.vph.2004.11.002","type":"journal-article","created":{"date-parts":[[2004,12,16]],"date-time":"2004-12-16T20:34:57Z","timestamp":1103229297000},"page":"7-15","source":"Crossref","is-referenced-by-count":12,"title":["Anti-inflammatory effects of a traditional Korean herbal formulation, Silsosangami, consisting of seven medicinal herbs: effect on hemolysis, neutrophil function, and gene expressions of iNOS and COX-2"],"prefix":"10.1016","volume":"42","author":[{"given":"Won-Hwan","family":"Park","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Hwan","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Choon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheorl-Ho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vph.2004.11.002_bib1","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1111\/j.1476-5381.1993.tb14007.x","article-title":"ZD1542, a potent thromboxane A2 synthase inhibitor and receptor antagonist in vitro","volume":"110","author":"Brownlie","year":"1993","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.vph.2004.11.002_bib2","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/BF00233250","article-title":"A study of the novel anti-inflammatory agent florifenine. Topical anti-inflammatory activity and influence on arachidonic acid metabolism and neutrophil functions","volume":"351","author":"Bustos","year":"1995","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"key":"10.1016\/j.vph.2004.11.002_bib3","first-page":"123","article-title":"Variabilin: a dual inhibitor of human secretory and cytosolic phospholipase A2 with anti-inflammatory activity","volume":"282","author":"Escrig","year":"1997","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.vph.2004.11.002_bib4","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1248\/bpb.26.271","article-title":"Anti-tumor promoting effect of glycosides from Prunus persica seeds","volume":"26","author":"Fukuda","year":"2003","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.vph.2004.11.002_bib5","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1002\/(SICI)1099-1573(199909)13:6<526::AID-PTR487>3.0.CO;2-O","article-title":"Effect of extract prepared from the roots of Paeonia lactiflora on endothelium-dependent relaxation and antioxidant enzyme activity in rats administered high-fat diet","volume":"13","author":"Goto","year":"1999","journal-title":"Phytother. Res."},{"key":"10.1016\/j.vph.2004.11.002_bib6","doi-asserted-by":"crossref","first-page":"25722","DOI":"10.1016\/S0021-9258(18)35667-9","article-title":"Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle","volume":"267","author":"Gross","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2004.11.002_bib7","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1248\/cpb.38.1224","article-title":"Inhibitory effects of tannins and related polyphenols on xanthine oxidase","volume":"38","author":"Hatano","year":"1990","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.vph.2004.11.002_bib8","doi-asserted-by":"crossref","first-page":"684","DOI":"10.7326\/0003-4819-121-9-199411010-00010","article-title":"The role of leukotrienes in inflammation","volume":"121","author":"Henderson","year":"1994","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.vph.2004.11.002_bib9","unstructured":"Hong, M.Y., 2001. Inhibitory effects of Hwaotang (HOT) on the atherosclerosis and the venous thrombosis. Thesis for the degree of doctor, Dongguk University, Kyungju, Korea."},{"key":"10.1016\/j.vph.2004.11.002_bib10","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0378-8741(01)00371-3","article-title":"Inhibitory effect of a Korean traditional medicine, Honghwain-Jahage (water extracts of Carthamus tinctorius L. seed and Hominis placenta) on interleukin-1-mediated bone resorption","volume":"29","author":"Hong","year":"2002","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.vph.2004.11.002_bib11","first-page":"370","article-title":"A nitric oxide synthase inhibitor reduces inflammation, down-regulates inflammatory cytokines and enhances interleukin-10 production in carrageenin-induced oedema in mice","volume":"82","author":"Ianaro","year":"1994","journal-title":"Immunology"},{"key":"10.1016\/j.vph.2004.11.002_bib12","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0021-9673(01)00969-4","article-title":"Quantitative determination of amygdalin epimers by cyclodextrin-modified micellar electrokinetic chromatography","volume":"923","author":"Isoza","year":"2001","journal-title":"J. Chromatogr., A"},{"key":"10.1016\/j.vph.2004.11.002_bib13","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1055\/s-0029-1243114","article-title":"Hyaluronidase inhibitory active 6H-dibenzo[b,d]pyran-6-ones from the feces of Trogopterus xanthipes","volume":"66","author":"Jeong","year":"2000","journal-title":"Planta Med."},{"key":"10.1016\/j.vph.2004.11.002_bib14","series-title":"Yu yanjiu xinbian","first-page":"521","author":"Jiang","year":"1990"},{"key":"10.1016\/j.vph.2004.11.002_bib15","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1093\/rheumatology\/35.8.711","article-title":"Expression of cyclooxygenase-2 in human and an animal model of rheumatoid arthritis","volume":"35","author":"Kang","year":"1996","journal-title":"Br. J. Rheumatol."},{"key":"10.1016\/j.vph.2004.11.002_bib16","series-title":"Clinic Lipid","first-page":"241","author":"Kim","year":"1995"},{"issue":"38","key":"10.1016\/j.vph.2004.11.002_bib17","first-page":"307","article-title":"Anti-thrombosis activity","volume":"8","author":"Kubo","year":"1994","journal-title":"Mokdanpi Study"},{"key":"10.1016\/j.vph.2004.11.002_bib18","series-title":"Herbal Theory","first-page":"54","author":"Lee","year":"1975"},{"key":"10.1016\/j.vph.2004.11.002_bib19","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1146\/annurev.immunol.15.1.323","article-title":"Nitric oxide and macrophage function","volume":"15","author":"MacMicking","year":"1997","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.vph.2004.11.002_bib20","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1002\/eji.1830250414","article-title":"Nitric oxide up-regulates the release of inflammatory mediators by mouse macrophages","volume":"25","author":"Marcinkiewicz","year":"1995","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.vph.2004.11.002_bib21","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1006\/abio.1993.1449","article-title":"A fluorometric assay for the measurement of nitrite in biological samples","volume":"214","author":"Misko","year":"1993","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.vph.2004.11.002_bib22","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1111\/j.2042-7158.1988.tb05173.x","article-title":"Selectivity of neutrophil 5-lipoxygenase and COX inhibition by an anti-inflammatory flavonoid glycoside and related aglycone flavonoids","volume":"40","author":"Moroney","year":"1988","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.vph.2004.11.002_bib23","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1248\/yakushi1947.108.6_555","article-title":"Screening test for platelet aggregation inhibitor in natural products. The active principle of Anemarrhenae Rhizoma","volume":"108","author":"Niwa","year":"1988","journal-title":"Yakugaku Zasshi"},{"key":"10.1016\/j.vph.2004.11.002_bib24","first-page":"197","article-title":"Traditional medicine","volume":"2","author":"Okuda","year":"1991","journal-title":"J. Act. Oxygens Free Radicals"},{"issue":"1","key":"10.1016\/j.vph.2004.11.002_bib25","first-page":"19","article-title":"A study of the influence of both of Shunqidaotantang and Huayutang on thrombosis, contusion-hyperemia, and hyperlipidemia","volume":"2","author":"Park","year":"1993","journal-title":"J. Dongguk Orient. Med."},{"key":"10.1016\/j.vph.2004.11.002_bib26","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1021\/np010039x","article-title":"Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: a drug discovery effort against Alzheimer's disease","volume":"65","author":"Park","year":"2002","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.vph.2004.11.002_bib27","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0014-2999(96)00140-9","article-title":"Evidence of peroxynitrite involvement in the carrageenan-induced rat paw ooedema","volume":"303","author":"Salvemini","year":"1996","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.vph.2004.11.002_bib28","doi-asserted-by":"crossref","first-page":"12013","DOI":"10.1073\/pnas.91.25.12013","article-title":"Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain","volume":"91","author":"Seibert","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.vph.2004.11.002_bib29","series-title":"Adult and Aged disease","first-page":"38","author":"Seo","year":"1992"},{"key":"10.1016\/j.vph.2004.11.002_bib30","unstructured":"Shin, M.G., 1986. Clinic Herbs Science, Seoul, Korea. NamSanDang Publishing, pp. 143, 453."},{"issue":"5","key":"10.1016\/j.vph.2004.11.002_bib31","first-page":"818","article-title":"An experimental study on inhibitory effects of Silsosangami on the atherosclerosis in hypercholesterolemic rabbits","volume":"15","author":"Shin","year":"2001","journal-title":"Korean J. Orient. Physiol. Pathol."},{"key":"10.1016\/j.vph.2004.11.002_bib32","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1002\/jlb.56.6.672","article-title":"Neutrophils, host defense, and inflammation: a double-edged sword","volume":"56","author":"Smith","year":"1994","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.vph.2004.11.002_bib33","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1248\/bpb1978.4.565","article-title":"Anti-inflammatory testing methods: comparative evaluation of mice and rats","volume":"4","author":"Sugishita","year":"1981","journal-title":"J. Pharmacobio-Dyn."},{"key":"10.1016\/j.vph.2004.11.002_bib34","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/j.1476-5381.1988.tb11557.x","article-title":"Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: biochemical assessment in vitro and ex vivo","volume":"94","author":"Tateson","year":"1988","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.vph.2004.11.002_bib35","series-title":"Dictionary of Traditional Chinese Medicine","first-page":"192","author":"Xie","year":"1984"},{"key":"10.1016\/j.vph.2004.11.002_bib36","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1055\/s-2001-18364","article-title":"Anti-thrombosis effect of paeoniflorin: evaluated in a photochemical reaction thrombosis model in vivo","volume":"67","author":"Ye","year":"2001","journal-title":"Planta Med."},{"key":"10.1016\/j.vph.2004.11.002_bib37","series-title":"Clinic of Traditional Chinese Medicine (\u25a1) in a Practical English\u2013Chinese Library of TCM","first-page":"102","author":"Zhang","year":"1990"},{"key":"10.1016\/j.vph.2004.11.002_bib38","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0024-3205(97)00395-0","article-title":"Inhibitory effects of jasmine green tea epicatechine isomers on free radical-induced lysis of red blood cells","volume":"61","author":"Zhang","year":"1997","journal-title":"Life Sci."},{"key":"10.1016\/j.vph.2004.11.002_bib39","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/0049-3848(90)90162-6","article-title":"The antiatherogenic effects of components isolated from pollen typhae","volume":"57","author":"Zhao","year":"1990","journal-title":"Thromb. Res."}],"container-title":["Vascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189104001132?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189104001132?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T18:01:01Z","timestamp":1625162461000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1537189104001132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,8]]}},"alternative-id":["S1537189104001132"],"URL":"https:\/\/doi.org\/10.1016\/j.vph.2004.11.002","relation":{},"ISSN":["1537-1891"],"issn-type":[{"value":"1537-1891","type":"print"}],"subject":[],"published":{"date-parts":[[2004,8]]}}}