{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T21:10:03Z","timestamp":1736457003188,"version":"3.32.0"},"reference-count":109,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vascular Pharmacology"],"published-print":{"date-parts":[[2006,10]]},"DOI":"10.1016\/j.vph.2005.08.031","type":"journal-article","created":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T14:43:11Z","timestamp":1152283391000},"page":"227-234","source":"Crossref","is-referenced-by-count":15,"title":["Neurokinin3 receptor regulation of the airways"],"prefix":"10.1016","volume":"45","author":[{"given":"Brendan J.","family":"Canning","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0014-2999(87)90244-5","article-title":"Relative potencies of neurokinins in guinea pig trachea and human bronchus","volume":"139","author":"Advenier","year":"1987","journal-title":"Eur. J. Pharmacol."},{"issue":"5 Pt 1","key":"10.1016\/j.vph.2005.08.031_bib2","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1164\/ajrccm\/146.5_Pt_1.1177","article-title":"Effects on the isolated human bronchus of SR 48968, a potent and selective nonpeptide antagonist of the neurokinin A (NK2) receptors","volume":"146","author":"Advenier","year":"1992","journal-title":"Am. Rev. Respir. Dis."},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib3","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0014-2999(02)02124-6","article-title":"SCH 206272: a potent, orally active tachykinin NK(1), NK(2), and NK(3) receptor antagonist","volume":"450","author":"Anthes","year":"2002","journal-title":"Eur. J. Pharmacol."},{"issue":"3 Pt 1","key":"10.1016\/j.vph.2005.08.031_bib4","first-page":"L309","article-title":"Substance P (NK1)- and neurokinin A (NK2)-receptor gene expression in inflammatory airway diseases","volume":"269","author":"Bai","year":"1995","journal-title":"Am. J. Physiol."},{"issue":"4","key":"10.1016\/j.vph.2005.08.031_bib5","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1002\/cne.903190408","article-title":"Substance P-immunoreactive sensory axons in the rat respiratory tract: a quantitative study of their distribution and role in neurogenic inflammation","volume":"319","author":"Baluk","year":"1992","journal-title":"J. Comp. Neurol."},{"issue":"4","key":"10.1016\/j.vph.2005.08.031_bib6","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1152\/jn.2001.85.4.1502","article-title":"Depression of windup of spinal neurons in the neonatal rat spinal cord in vitro by an NK3 tachykinin receptor antagonist","volume":"85","author":"Barbieri","year":"2001","journal-title":"J. Neurophysiol."},{"issue":"8475","key":"10.1016\/j.vph.2005.08.031_bib7","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/S0140-6736(86)90777-4","article-title":"Asthma as an axon reflex","volume":"1","author":"Barnes","year":"1986","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib8","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1476-5381.1994.tb14030.x","article-title":"Facilitatory effects of selective agonists for tachykinin receptors on cholinergic neurotransmission: evidence for species differences","volume":"111","author":"Belvisi","year":"1994","journal-title":"Br. J. Pharmacol."},{"issue":"4 Pt 1","key":"10.1016\/j.vph.2005.08.031_bib9","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1164\/ajrccm\/148.4_Pt_1.909","article-title":"Capsaicin increases airflow resistance in guinea pigs in vivo by activating both NK2 and NK1 tachykinin receptors","volume":"148","author":"Bertrand","year":"1993","journal-title":"Am. Rev. Respir. Dis."},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib10","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/j.1476-5381.1992.tb12763.x","article-title":"Tachykinin receptors in rabbit airways\u2014characterization by functional, autoradiographic and binding studies","volume":"107","author":"Black","year":"1992","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib11","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1006\/pupt.2002.0363","article-title":"Interactions between vagal afferent nerve subtypes mediating cough","volume":"15","author":"Canning","year":"2002","journal-title":"Pulm. Pharmacol. Ther."},{"issue":"Pt 3","key":"10.1016\/j.vph.2005.08.031_bib12","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1113\/jphysiol.1994.sp020388","article-title":"Evidence that antidromically stimulated vagal afferents activate inhibitory neurones innervating guinea-pig trachealis","volume":"480","author":"Canning","year":"1994","journal-title":"J. Physiol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib13","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/S0022-3565(24)37235-0","article-title":"Pharmacological analysis of the tachykinin receptors that mediate activation of nonadrenergic, noncholinergic relaxant nerves that innervate guinea pig trachealis","volume":"284","author":"Canning","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"6","key":"10.1016\/j.vph.2005.08.031_bib14","doi-asserted-by":"crossref","first-page":"2642","DOI":"10.1152\/jappl.2001.91.6.2642","article-title":"Multiple mechanisms of reflex bronchospasm in guinea pigs","volume":"91","author":"Canning","year":"2001","journal-title":"J. Appl. Physiol."},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib15","doi-asserted-by":"crossref","first-page":"R320","DOI":"10.1152\/ajpregu.00001.2002","article-title":"Endogenous neurokinins facilitate synaptic transmission in guinea pig airway parasympathetic ganglia","volume":"283","author":"Canning","year":"2002","journal-title":"Am. J. Physiol. Regul., Integr. Comp. Physiol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib16","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0014-2999(00)00199-0","article-title":"Tachykinin NK(2) receptors facilitate acetylcholine release from guinea-pig isolated trachea","volume":"396","author":"D'Agostino","year":"2000","journal-title":"Eur. J. Pharmacol."},{"issue":"5\u20136","key":"10.1016\/j.vph.2005.08.031_bib17","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1006\/pupt.1998.0104","article-title":"A tachykinin NK3 receptor antagonist, SR 142801 (osanetant), prevents substance P-induced bronchial hyperreactivity in guinea-pigs","volume":"10","author":"Daoui","year":"1997","journal-title":"Pulm. Pharmacol. Ther."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib18","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1164\/ajrccm.158.1.9705052","article-title":"Involvement of tachykinin NK3 receptors in citric acid-induced cough and bronchial responses in guinea pigs","volume":"158","author":"Daoui","year":"1998","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib19","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/sj.bjp.0703278","article-title":"Neurokinin B- and specific tachykinin NK(3) receptor agonists-induced airway hyperresponsiveness in the guinea-pig","volume":"130","author":"Daoui","year":"2000","journal-title":"Br. J. Pharmacol."},{"issue":"2\u20133","key":"10.1016\/j.vph.2005.08.031_bib20","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0014-2999(01)01505-9","article-title":"Tachykinin NK(3) receptor agonists induced microvascular leakage hypersensitivity in the guinea-pig airways","volume":"433","author":"Daoui","year":"2001","journal-title":"Eur. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib21","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1183\/09031936.02.00250902","article-title":"Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation","volume":"20","author":"Daoui","year":"2002","journal-title":"Eur. Respir. J."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib22","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1165\/ajrcmb.14.3.8845170","article-title":"Neurochemical characterization of intrinsic neurons in ferret tracheal plexus","volume":"14","author":"Dey","year":"1996","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib23","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/(SICI)1096-9861(19960108)364:2<290::AID-CNE8>3.0.CO;2-0","article-title":"Localization of the neuromedin K receptor (NK3) in the central nervous system of the rat","volume":"364","author":"Ding","year":"1996","journal-title":"J. Comp. Neurol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib24","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0143-4179(87)90088-6","article-title":"Selective agonists for substance P and neurokinin receptors","volume":"10","author":"Drapeau","year":"1987","journal-title":"Neuropeptides"},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib25","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1152\/jappl.1994.77.1.147","article-title":"Responses of lung parenchyma and airways to tachykinin peptides in piglets","volume":"77","author":"Dreshaj","year":"1994","journal-title":"J. Appl. Physiol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib26","first-page":"95","article-title":"Pharmacological examination of receptors mediating contractile responses to tachykinins in airways isolated from human, guinea pig and hamster","volume":"267","author":"Ellis","year":"1993","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib27","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1164\/ajrccm.155.2.9032224","article-title":"Tachykinin-independent effects of capsaicin on smooth muscle in human isolated bronchi","volume":"155","author":"Ellis","year":"1997","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"5","key":"10.1016\/j.vph.2005.08.031_bib28","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1139\/y02-041","article-title":"Biochemical and pharmacological activities of SSR 146977, a new potent nonpeptide tachykinin NK3 receptor antagonist","volume":"80","author":"Emonds-Alt","year":"2002","journal-title":"Can. J. Physiol. Pharm."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib29","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1164\/ajrccm.152.3.7663799","article-title":"Effect of an NK1 receptor antagonist (CP-99,994) on hypertonic saline-induced bronchoconstriction and cough in male asthmatic subjects","volume":"152","author":"Fahy","year":"1995","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"5","key":"10.1016\/j.vph.2005.08.031_bib30","doi-asserted-by":"crossref","first-page":"L1033","DOI":"10.1152\/ajplung.00063.2002","article-title":"In vitro sensitization of human bronchus by beta2-adrenergic agonists","volume":"283","author":"Faisy","year":"2002","journal-title":"Am. J. Physiol., Lung Cell. Mol. Physiol."},{"issue":"6","key":"10.1016\/j.vph.2005.08.031_bib108","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1111\/j.1476-5381.1996.tb16725.x","article-title":"Evidence that tachykinins relax the guinea-pig trachea via nitric oxide release and by stimulation of a septide-insensitive NK1 receptor","volume":"117","author":"Figini","year":"1996","journal-title":"Br. J. Pharmacol"},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib31","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1164\/ajrccm.154.1.8680682","article-title":"Nitric oxide synthase in neurons and nerve fibers of lower airways and in vagal sensory ganglia of man. Correlation with neuropeptides","volume":"154","author":"Fischer","year":"1996","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib32","doi-asserted-by":"crossref","first-page":"L344","DOI":"10.1152\/ajplung.2000.278.2.L344","article-title":"Substance P and neurokinin-1 receptor expression by intrinsic airway neurons in the rat","volume":"278","author":"Fontan","year":"2000","journal-title":"Am. J. Physiol., Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.vph.2005.08.031_bib33","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1054\/npep.2001.0858","article-title":"NK(3) receptors in the feline nucleus tractus solitarius are not involved with the muscle pressor response","volume":"35","author":"Fry","year":"2001","journal-title":"Neuropeptides"},{"issue":"5","key":"10.1016\/j.vph.2005.08.031_bib34","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1038\/sj.bjp.0704572","article-title":"Tachykinins via tachykinin NK(2) receptor activation mediate ozone-induced increase in the permeability of the tracheal mucosa in guinea-pigs","volume":"135","author":"Fu","year":"2002","journal-title":"Br. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.vph.2005.08.031_bib35","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1152\/jappl.1985.58.4.1080","article-title":"Bronchoconstrictor response to inhaled capsaicin in humans","volume":"58","author":"Fuller","year":"1985","journal-title":"J. Appl. Physiol."},{"issue":"1\u20132","key":"10.1016\/j.vph.2005.08.031_bib36","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/S0006-8993(03)02871-3","article-title":"Tachykinin receptor (NK(1), NK(2), NK(3)) binding sites in the rat caudal brainstem following neonatal capsaicin administration","volume":"979","author":"Geraghty","year":"2003","journal-title":"Brain Res."},{"issue":"5","key":"10.1016\/j.vph.2005.08.031_bib37","first-page":"515","article-title":"Tachykinin-induced phosphoinositide breakdown in airway smooth muscle and epithelium: relationship to contraction","volume":"33","author":"Grandordy","year":"1988","journal-title":"Mol. Pharmacol."},{"issue":"Pt 3","key":"10.1016\/j.vph.2005.08.031_bib38","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1113\/jphysiol.2002.018846","article-title":"Neurokinin B induces oedema formation in mouse lung via tachykinin receptor-independent mechanisms","volume":"543","author":"Grant","year":"2002","journal-title":"J. Physiol."},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib39","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/j.1600-0773.1981.tb00884.x","article-title":"Pharmacological characterization of the autonomous innervation of the guinea pig tracheobronchial smooth muscle","volume":"49","author":"Grundstrom","year":"1981","journal-title":"Acta Pharm. Toxicol. (Copenh.)"},{"issue":"11","key":"10.1016\/j.vph.2005.08.031_bib40","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1136\/thx.52.11.964","article-title":"Effects of inhaled histamine, methacholine and capsaicin on sputum levels of alpha 2 macroglobulin","volume":"52","author":"Halldorsdottir","year":"1997","journal-title":"Thorax"},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib41","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.brainresbull.2003.11.003","article-title":"Distinct regional distributions of NK1 and NK3 neurokinin receptor immunoreactivity in rat brainstem gustatory centers","volume":"63","author":"Harrison","year":"2004","journal-title":"Brain Res. Bull."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib42","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1124\/jpet.300.1.314","article-title":"Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyper-reactivity in guinea pigs","volume":"300","author":"Hay","year":"2002","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib43","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1165\/ajrcmb.13.3.7654385","article-title":"Neuropeptide-containing nerves in endobronchial biopsies from asthmatic and nonasthmatic subjects","volume":"13","author":"Howarth","year":"1995","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0167-0115(85)90082-5","article-title":"Multiple tachykinins (neurokinin A, neuropeptide K and substance P) in capsaicin-sensitive sensory neurons in the guinea-pig","volume":"13","author":"Hua","year":"1985","journal-title":"Regul Pept."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib45","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1164\/ajrccm.153.3.8630576","article-title":"A neurokinin 1-receptor antagonist improves exercise-induced airway narrowing in asthmatic patients","volume":"153","author":"Ichinose","year":"1996","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib46","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1136\/thx.50.3.217","article-title":"Neurogenic inflammation in human airways: is it important?","volume":"50","author":"Joos","year":"1995","journal-title":"Thorax"},{"issue":"6 Pt 1","key":"10.1016\/j.vph.2005.08.031_bib47","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1164\/ajrccm.153.6.8665034","article-title":"The effect of inhaled FK224, a tachykinin NK-1 and NK-2 receptor antagonist, on neurokinin A-induced bronchoconstriction in asthmatics","volume":"153","author":"Joos","year":"1996","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib48","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0014-2999(97)81929-2","article-title":"Role of 5-hydroxytryptamine and mast cells in the tachykinin-induced contraction of rat trachea in vitro","volume":"338","author":"Joos","year":"1997","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib49","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1183\/09031936.03.00101902","article-title":"Dual tachykinin NK1\/NK2 antagonist DNK333 inhibits neurokinin A-induced bronchoconstriction in asthma patients","volume":"23","author":"Joos","year":"2004","journal-title":"Eur. Respir. J."},{"issue":"1 Pt 1","key":"10.1016\/j.vph.2005.08.031_bib50","first-page":"L119","article-title":"Migration and proliferation of guinea pig and human airway epithelial cells in response to tachykinins","volume":"269","author":"Kim","year":"1995","journal-title":"Am. J. Physiol."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib51","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/0306-4522(92)90239-X","article-title":"The sensory and sympathetic innervation of guinea-pig lung and trachea as studied by retrograde neuronal tracing and double-labelling immunohistochemistry","volume":"49","author":"Kummer","year":"1992","journal-title":"Neuroscience"},{"issue":"6","key":"10.1016\/j.vph.2005.08.031_bib52","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.phrs.2004.07.002","article-title":"Tachykinin NK3-receptor deficiency does not inhibit pulmonary eosinophilia in allergic mice","volume":"50","author":"Kung","year":"2004","journal-title":"Pharmacol. Res."},{"issue":"9","key":"10.1016\/j.vph.2005.08.031_bib53","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1164\/rccm.2112018","article-title":"Three-dimensional mapping of sensory innervation with substance p in porcine bronchial mucosa: comparison with human airways","volume":"166","author":"Lamb","year":"2002","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib54","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/ar.a.10005","article-title":"Functional morphology and physiological properties of bronchopulmonary C-fiber afferents","volume":"270","author":"Lee","year":"2003","journal-title":"Anat. Rec. A Discov. Mol. Cell Evol. Biol."},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib55","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1476-5381.1992.tb14243.x","article-title":"Inhibition of neurogenic plasma exudation in guinea-pig airways by CP-96,345, a new non-peptide NK1 receptor antagonist","volume":"105","author":"Lei","year":"1992","journal-title":"Br. J. Pharmacol."},{"issue":"1\u20132","key":"10.1016\/j.vph.2005.08.031_bib56","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0304-3959(98)00222-X","article-title":"Spinal neurokinin3 receptors mediate thermal but not mechanical hyperalgesia via nitric oxide","volume":"80","author":"Linden","year":"1999","journal-title":"Pain"},{"issue":"1\u20132","key":"10.1016\/j.vph.2005.08.031_bib57","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0304-3959(98)00223-1","article-title":"Spinal neurokin3 receptors facilitate the nociceptive flexor reflex via a pathway involving nitric oxide","volume":"80","author":"Linden","year":"1999","journal-title":"Pain"},{"issue":"4","key":"10.1016\/j.vph.2005.08.031_bib58","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1748-1716.1982.tb07116.x","article-title":"Capsaicin-sensitive vagal neurons involved in control of vascular permeability in rat trachea","volume":"115","author":"Lundberg","year":"1982","journal-title":"Acta Physiol. Scand."},{"issue":"4","key":"10.1016\/j.vph.2005.08.031_bib59","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1748-1716.1982.tb07170.x","article-title":"Bronchial smooth muscle contraction induced by stimulation of capsaicin-sensitive sensory neurons","volume":"116","author":"Lundberg","year":"1982","journal-title":"Acta Physiol. Scand."},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib60","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/BF00217848","article-title":"Substance P-immunoreactive sensory nerves in the lower respiratory tract of various mammals including man","volume":"235","author":"Lundberg","year":"1984","journal-title":"Cell Tissue Res."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib61","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/BF00178976","article-title":"Sensory nerves, vascular endothelium and neurogenic relaxation of the guinea-pig isolated pulmonary artery","volume":"342","author":"Maggi","year":"1990","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib62","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1165\/rcmb.4635","article-title":"Airway smooth muscle cells express functional neurokinin-1 receptors and the nerve-derived preprotachykinin-a gene: regulation by passive sensitization","volume":"28","author":"Maghni","year":"2003","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"4","key":"10.1016\/j.vph.2005.08.031_bib63","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1111\/j.1476-5381.1992.tb09086.x","article-title":"Bronchodilatation by tachykinins and capsaicin in the mouse main bronchus","volume":"105","author":"Manzini","year":"1992","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib64","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S1471-4892(02)00151-0","article-title":"Central nervous system control of the airways: pharmacological implications","volume":"2","author":"Mazzone","year":"2002","journal-title":"Curr. Opin. Pharmacol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib65","doi-asserted-by":"crossref","first-page":"R86","DOI":"10.1152\/ajpregu.00007.2002","article-title":"Synergistic interactions between airway afferent nerve subtypes mediating reflex bronchospasm in guinea pigs","volume":"283","author":"Mazzone","year":"2002","journal-title":"Am. J. Physiol. Regul., Integr. Comp. Physiol."},{"key":"10.1016\/j.vph.2005.08.031_bib66","series-title":"Handbook of Experimental Pharmacology, Volume 164, Tachykinins","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-18891-6_8","article-title":"Tachykinin NK3 receptor antagonists","author":"Mazzone","year":"2004"},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib67","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/sj.bjp.0702522","article-title":"Respiratory action of capsaicin microinjected into the nucleus of the solitary tract: involvement of vanilloid and tachykinin receptors","volume":"127","author":"Mazzone","year":"1999","journal-title":"Br. J. Pharmacol."},{"issue":"6","key":"10.1016\/j.vph.2005.08.031_bib68","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1038\/sj.bjp.0703172","article-title":"Respiratory actions of tachykinins in the nucleus of the solitary tract: characterization of receptors using selective agonists and antagonists","volume":"129","author":"Mazzone","year":"2000","journal-title":"Br. J. Pharmacol."},{"issue":"Pt 2","key":"10.1016\/j.vph.2005.08.031_bib69","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1113\/jphysiol.2005.093153","article-title":"Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs","volume":"569","author":"Mazzone","year":"2005","journal-title":"J. Physiol."},{"issue":"25","key":"10.1016\/j.vph.2005.08.031_bib70","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1016\/0024-3205(89)90004-0","article-title":"Effect of sensory neuropeptides on canine bronchial and pulmonary vessels in vitro","volume":"45","author":"McCormack","year":"1989","journal-title":"Life Sci."},{"issue":"5","key":"10.1016\/j.vph.2005.08.031_bib71","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/BF01260988","article-title":"Neurogenic inflammation in the rat trachea. I. Changes in venules, leucocytes and epithelial cells","volume":"17","author":"McDonald","year":"1988","journal-title":"J. Neurocytol."},{"issue":"5","key":"10.1016\/j.vph.2005.08.031_bib72","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/BF01260989","article-title":"Neurogenic inflammation in the rat trachea. II. Identity and distribution of nerves mediating the increase in vascular permeability","volume":"17","author":"McDonald","year":"1988","journal-title":"J. Neurocytol."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib73","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0014-2999(00)00763-9","article-title":"Role of substance P and tachykinin receptor antagonists in citric acid-induced cough in pigs","volume":"408","author":"Moreaux","year":"2000","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib74","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1046\/j.1472-8206.2001.00008.x","article-title":"Role of bradykinin and tachykinins in the potentiation by enalapril of coughing induced by citric acid in pigs","volume":"15","author":"Moreaux","year":"2001","journal-title":"Fundam. Clin. Pharmacol."},{"issue":"4","key":"10.1016\/j.vph.2005.08.031_bib75","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/0306-4522(92)90285-A","article-title":"Distribution of neurokinin B in rat spinal cord and peripheral tissues: comparison with neurokinin A and substance P and effects of neonatal capsaicin treatment","volume":"48","author":"Moussaoui","year":"1992","journal-title":"Neuroscience"},{"issue":"1\u20133","key":"10.1016\/j.vph.2005.08.031_bib76","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ejphar.2004.07.071","article-title":"Involvement of enhanced neurokinin NK3 receptor expression in the severe asthma guinea pig model","volume":"498","author":"Mukaiyama","year":"2004","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib77","first-page":"403","article-title":"Effects of FK224, a novel compound NK1 and NK2 receptor antagonist, on airway constriction and airway edema induced by neurokinins and sensory nerve stimulation in guinea pigs","volume":"262","author":"Murai","year":"1992","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.vph.2005.08.031_bib78","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1113\/jphysiol.1993.sp019881","article-title":"Electrophysiological effects of tachykinins and capsaicin on guinea-pig bronchial parasympathetic ganglion neurones","volume":"470","author":"Myers","year":"1993","journal-title":"J. Physiol."},{"issue":"2","key":"10.1016\/j.vph.2005.08.031_bib79","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S0165-1838(96)00081-1","article-title":"Anatomical and electrophysiological comparison of the sensory innervation of bronchial and tracheal parasympathetic ganglion neurons","volume":"61","author":"Myers","year":"1996","journal-title":"J. Auton. Nerv. Syst."},{"key":"10.1016\/j.vph.2005.08.031_bib80","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1164\/rccm.200405-600OC","article-title":"A novel role for tachykinin neurokinin-3 receptors in regulation of human bronchial ganglia neurons","volume":"171","author":"Myers","year":"2005","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib81","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0034-5687(94)90040-X","article-title":"Tachykinins induce a [Ca2+]i rise in the acinar cells of feline tracheal submucosal gland","volume":"98","author":"Nagaki","year":"1994","journal-title":"Respir. Physiol."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib82","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1164\/ajrccm\/140.3.679","article-title":"Characterization of neurokinin effects and receptor selectivity in human isolated bronchi","volume":"140","author":"Naline","year":"1989","journal-title":"Am. Rev. Respir. Dis."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib83","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0014-2999(01)01036-6","article-title":"Inhibition of inflammatory cell recruitment by the tachykinin NK(3)-receptor antagonist, SR 142801, in a murine model of asthma","volume":"421","author":"Nenan","year":"2001","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib84","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0022-3565(24)35294-2","article-title":"Pharmacological examination of the neurokinin-1 receptor mediating relaxation of human intralobar pulmonary artery","volume":"292","author":"Pedersen","year":"2000","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib85","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/sj.bjp.0705029","article-title":"Tachykinin NK3 and NK1 receptor activation elicits secretion from porcine airway submucosal glands","volume":"138","author":"Phillips","year":"2003","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.vph.2005.08.031_bib86","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0024-3205(02)02243-9","article-title":"SR 142801, a tachykinin NK(3) receptor antagonist, prevents beta(2)-adrenoceptor agonist-induced hyperresponsiveness to neurokinin A in guinea-pig isolated trachea","volume":"72","author":"Pinto","year":"2002","journal-title":"Life Sci."},{"issue":"2\u20133","key":"10.1016\/j.vph.2005.08.031_bib87","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ejphar.2004.05.016","article-title":"mRNA expression of tachykinins and tachykinin receptors in different human tissues","volume":"494","author":"Pinto","year":"2004","journal-title":"Eur. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib88","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1046\/j.1440-1843.2001.00333.x","article-title":"Pre-protachykinin-A mRNA is increased in the airway epithelium of smokers with chronic bronchitis","volume":"6","author":"Reynolds","year":"2001","journal-title":"Respirology"},{"key":"10.1016\/j.vph.2005.08.031_bib89","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0034-5687(00)00209-7","article-title":"Motor control of airway goblet cells and glands","volume":"125","author":"Rogers","year":"2001","journal-title":"Respir. Physiol."},{"issue":"4","key":"10.1016\/j.vph.2005.08.031_bib90","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1111\/j.1476-5381.1988.tb11745.x","article-title":"Effects and interactions of sensory neuropeptides on airway microvascular leakage in guinea-pigs","volume":"95","author":"Rogers","year":"1988","journal-title":"Br. J. Pharmacol."},{"issue":"2\u20133","key":"10.1016\/j.vph.2005.08.031_bib91","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0014-2999(89)90322-1","article-title":"Effects of tachykinins on mucus secretion in human bronchi in vitro","volume":"174","author":"Rogers","year":"1989","journal-title":"Eur. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib92","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1124\/mol.58.3.552","article-title":"Evidence that the proposed novel human \u201cneurokinin-4\u201d receptor is pharmacologically similar to the human neurokinin-3 receptor but is not of human origin","volume":"58","author":"Sarau","year":"2000","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.vph.2005.08.031_bib93","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0014-2999(01)00732-4","article-title":"Molecular and pharmacological characterization of the murine tachykinin NK(3) receptor","volume":"413","author":"Sarau","year":"2001","journal-title":"Eur. J. Pharmacol."},{"issue":"6","key":"10.1016\/j.vph.2005.08.031_bib94","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1164\/ajrccm\/137.6.1330","article-title":"Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by bradykinin, histamine, dimethylphenyl piperazinium, and vagal nerve stimulation","volume":"137","author":"Saria","year":"1988","journal-title":"Am. Rev. Respir. Dis."},{"issue":"4","key":"10.1016\/j.vph.2005.08.031_bib95","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/j.1748-1716.1992.tb09459.x","article-title":"Inhibitory effects of capsazepine and the NK2 antagonist SR 48968 on bronchoconstriction evoked by sensory nerve stimulation in guinea-pigs","volume":"146","author":"Satoh","year":"1992","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/j.vph.2005.08.031_bib109","article-title":"The triple neurokinin-receptor antagonist CS-003 inhibits neurokinin A-induced bronchoconstriction in patients with asthma","author":"Schelfhout","year":"2005","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.vph.2005.08.031_bib96","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/sj.bjp.0702093","article-title":"NK-3 receptors mediate enhancement of substance P release from capsaicin-sensitive spinal cord afferent terminals","volume":"125","author":"Schmid","year":"1998","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib97","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1002\/(SICI)1096-9861(19960826)372:3<395::AID-CNE5>3.0.CO;2-Y","article-title":"In situ hybridization analysis of the distribution of neurokinin-3 mRNA in the rat central nervous system","volume":"372","author":"Shughrue","year":"1996","journal-title":"J. Comp. Neurol."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib98","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/1096-9861(20001023)426:3<413::AID-CNE6>3.0.CO;2-A","article-title":"Distribution of Fos-like immunoreactivity within the rat brain following intraventricular injection of the selective NK(3) receptor agonist senktide","volume":"426","author":"Smith","year":"2000","journal-title":"J. Comp. Neurol."},{"issue":"1\u20133","key":"10.1016\/j.vph.2005.08.031_bib99","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.regpep.2004.07.017","article-title":"Inflammatory cells as source of tachykinin induced mucus secretion in chronic bronchitis","volume":"124","author":"Springer","year":"2005","journal-title":"Regul Pept."},{"issue":"5","key":"10.1016\/j.vph.2005.08.031_bib100","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1152\/jappl.1995.78.5.1679","article-title":"Sensory nerve- and neuropeptide-mediated relaxation responses in airways of Sprague\u2013Dawley rats","volume":"78","author":"Szarek","year":"1995","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.vph.2005.08.031_bib101","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1113\/jphysiol.1995.sp020950","article-title":"Role of nitric oxide in tachykinin-induced increase in potential difference of rabbit tracheal mucosa","volume":"488","author":"Tamaoki","year":"1995","journal-title":"J. Physiol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib102","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0167-0115(95)00121-2","article-title":"Tachykinins stimulate nitric oxide generation by canine cultured tracheal epithelium","volume":"60","author":"Tamaoki","year":"1995","journal-title":"Regul Pept."},{"issue":"3","key":"10.1016\/j.vph.2005.08.031_bib103","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1164\/ajrccm\/136.3.718","article-title":"Neurokinin A as a potent bronchoconstrictor","volume":"136","author":"Uchida","year":"1987","journal-title":"Am. Rev. Respir. Dis."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib104","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1183\/09031936.98.12010017","article-title":"The effect of the NK2 tachykinin receptor antagonist SR 48968 (saredutant) on neurokinin A-induced bronchoconstriction in asthmatics","volume":"12","author":"Van Schoor","year":"1998","journal-title":"Eur. Respir. J."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib105","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1054\/npep.1999.0014","article-title":"Effects of selective tachykinin-receptor antagonists on tachykinin-induced airway mucus secretion in the rat","volume":"33","author":"Wagner","year":"1999","journal-title":"Neuropeptides"},{"issue":"6 Pt 1","key":"10.1016\/j.vph.2005.08.031_bib106","first-page":"L889","article-title":"Protective effect of substance P on permeability of airway epithelial cells in culture","volume":"271","author":"Yu","year":"1996","journal-title":"Am. J. Physiol."},{"issue":"1","key":"10.1016\/j.vph.2005.08.031_bib107","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0028-3908(99)00087-8","article-title":"NK3 receptor blockade prevents hyperalgesia and the associated spinal cord substance P release in monoarthritic rats","volume":"39","author":"Zaratin","year":"2000","journal-title":"Neuropharmacology"}],"container-title":["Vascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153718910600156X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153718910600156X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T20:40:49Z","timestamp":1736455249000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S153718910600156X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":109,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["S153718910600156X"],"URL":"https:\/\/doi.org\/10.1016\/j.vph.2005.08.031","relation":{},"ISSN":["1537-1891"],"issn-type":[{"type":"print","value":"1537-1891"}],"subject":[],"published":{"date-parts":[[2006,10]]}}}