{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T14:30:12Z","timestamp":1759588212195,"version":"3.37.0"},"reference-count":83,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2009,8,1]],"date-time":"2009-08-01T00:00:00Z","timestamp":1249084800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vascular Pharmacology"],"published-print":{"date-parts":[[2009,8]]},"DOI":"10.1016\/j.vph.2009.04.004","type":"journal-article","created":{"date-parts":[[2009,5,5]],"date-time":"2009-05-05T09:31:38Z","timestamp":1241515898000},"page":"101-109","source":"Crossref","is-referenced-by-count":26,"title":["Global upregulation of gene expression associated with renal dysfunction in DOCA\u2013salt-induced hypertensive rats occurs via signaling cascades involving epidermal growth factor receptor: A microarray analysis"],"prefix":"10.1016","volume":"51","author":[{"given":"Ibrahim F.","family":"Benter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halit","family":"Canatan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustapha","family":"Benboubetra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariam H.M.","family":"Yousif","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saghir","family":"Akhtar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vph.2009.04.004_bib1","doi-asserted-by":"crossref","first-page":"29,857","DOI":"10.1074\/jbc.M313320200","article-title":"S-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells","volume":"279","author":"Adachi","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2009.04.004_bib2","doi-asserted-by":"crossref","first-page":"3623","DOI":"10.1172\/JCI33494","article-title":"Nonviral delivery of synthetic siRNAs in vivo","volume":"117","author":"Akhtar","year":"2007","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.vph.2009.04.004_bib3","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1517\/14728214.12.2.271","article-title":"Ras as a therapeutic target in hemotologic maligancies","volume":"12","author":"Alvarado","year":"2007","journal-title":"Expert Opin. Emerg. Drugs"},{"key":"10.1016\/j.vph.2009.04.004_bib4","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjaminin","year":"1995","journal-title":"J. R. Stat. Soc., B"},{"key":"10.1016\/j.vph.2009.04.004_bib5","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.phrs.2005.06.001","article-title":"Signal transduction involving Ras-GTPase contributes to development of hypertension and end-organ damage in spontaneously hypertensive rats-treated with L-NAME","volume":"52","author":"Benter","year":"2005","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.vph.2009.04.004_bib6","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.phrs.2005.04.001","article-title":"Inhibition of Ca2+\/calmodulin-dependent protein kinase II, RAS-GTPase and 20-hydroxyeicosatetraenoic acid attenuates the development of diabetes-induced vascular dysfunction in the rat carotid artery","volume":"52","author":"Benter","year":"2005","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.vph.2009.04.004_bib7","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/sj.bjp.0706238","article-title":"Epidermal growth factor receptor tyrosine kinase-mediated signalling contributes to diabetes-induced vascular dysfunction in the mesenteric bed","volume":"145","author":"Benter","year":"2005","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.vph.2009.04.004_bib8","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1159\/000085904","article-title":"Diabetes-induced renal vascular dysfunction is normalized by inhibition of epidermal growth factor receptor tyrosine kinase","volume":"42","author":"Benter","year":"2005","journal-title":"J. Vasc. Res."},{"key":"10.1016\/j.vph.2009.04.004_bib9","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1038\/ncpneph0299","article-title":"The benefits of renin\u2013angiotensin blockade in hypertension are dependent on blood-pressure lowering","volume":"2","author":"Bidani","year":"2006","journal-title":"Nat. Clin. Pract. Nephrol."},{"key":"10.1016\/j.vph.2009.04.004_bib10","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/01.hjh.0000191244.91314.9d","article-title":"Blockade of the renin\u2013angiotensin\u2013aldosterone system: a key therapeutic strategy to reduce renal and cardiovascular events in patients with diabetes","volume":"24","author":"Burnier","year":"2006","journal-title":"J. Hypertens."},{"key":"10.1016\/j.vph.2009.04.004_bib11","doi-asserted-by":"crossref","first-page":"13,801","DOI":"10.1073\/pnas.0600362103","article-title":"Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor","volume":"103","author":"Cai","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.vph.2009.04.004_bib12","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/cbf.1425","article-title":"The effect of cardiac ischemic preconditioning on rat left ventricular gene expression profile","volume":"26","author":"Canatan","year":"2008","journal-title":"Cell Biochem. Funct."},{"key":"10.1016\/j.vph.2009.04.004_bib13","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1161\/01.HYP.37.2.569","article-title":"Tyrosine kinase involvement in renal arteriolar constrictor responses to angiotensin II","volume":"37","author":"Carmines","year":"2001","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib14","doi-asserted-by":"crossref","first-page":"16,045","DOI":"10.1074\/jbc.M011766200","article-title":"c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation","volume":"276","author":"Chen","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2009.04.004_bib15","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1056\/NEJMra0707704","article-title":"EGFR antagonists in cancer treatment","volume":"358","author":"Ciardiello","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.vph.2009.04.004_bib16","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1001\/archinte.161.9.1207","article-title":"Prevalence of high blood pressure and elevated serum creatinine level in the United States: findings from the third National Health and Nutrition Examination Survey (1988\u20131994)","volume":"161","author":"Coresh","year":"2001","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.vph.2009.04.004_bib17","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1161\/hc0802.104324","article-title":"Protection of human endothelial cells from oxidative stress: role of Ras-ERK1\/2 signaling","volume":"105","author":"Cuda","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.vph.2009.04.004_bib18","doi-asserted-by":"crossref","first-page":"F1049","DOI":"10.1152\/ajprenal.00132.2004","article-title":"EGFR-independent activation of p38 MAPK and EGFR-dependent activation of ERK1\/2 are required for ROS-induced renal cell death","volume":"287","author":"Dong","year":"2004","journal-title":"Am. J. Physiol., Renal Physiol."},{"key":"10.1016\/j.vph.2009.04.004_bib19","unstructured":"Eguchi, S., Iwasaki, H., Ueno, H., Frank, G.D., Motley, E.D., Eguchi, K., et al., Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt. J Biol Chem. 1999; 274: 36,843-351."},{"key":"10.1016\/j.vph.2009.04.004_bib20","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1055\/s-0037-1614389","article-title":"Rapid release of matrix metalloproteinase-2 by thrombin in the rat aorta: modulation by protein tyrosine kinase\/phosphatase","volume":"82","author":"Fernandez-Patron","year":"1999","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.vph.2009.04.004_bib21","first-page":"H976","article-title":"Epidermal growth factor: a potent vasoconstrictor in experimental hypertension","volume":"276","author":"Florian","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.vph.2009.04.004_bib22","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1096\/fj.03-0702fje","article-title":"Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition","volume":"18","author":"Fran\u00e7ois","year":"2004","journal-title":"FASEB J."},{"key":"10.1016\/j.vph.2009.04.004_bib23","doi-asserted-by":"crossref","first-page":"3120","DOI":"10.1210\/en.141.9.3120","article-title":"Involvement of reactive oxygen species in the activation of tyrosine kinase and extracellular signal-regulated kinase by angiotensin II","volume":"141","author":"Frank","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.vph.2009.04.004_bib24","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.steroids.2007.12.008","article-title":"Nongenotropic aldosterone effects and the EGFR: interaction and biological relevance","volume":"73","author":"Grossmann","year":"2008","journal-title":"Steroids"},{"key":"10.1016\/j.vph.2009.04.004_bib25","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1161\/01.RES.0000109413.57726.91","article-title":"Agonist-induced activation of matrix metalloproteinase-7 promotes vasoconstriction through the epidermal growth factor-receptor pathway","volume":"94","author":"Hao","year":"2004","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2009.04.004_bib26","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1042\/BJ20051628","article-title":"Ras triggers acidosis-induced activation of the extracellular-signal-regulated kinase pathway in cardiac myocytes","volume":"399","author":"Haworth","year":"2006","journal-title":"Biochem. J."},{"key":"10.1016\/j.vph.2009.04.004_bib27","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1161\/01.HYP.33.1.283","article-title":"Interleukin-1beta regulation of the human brain natriuretic peptide promoter involves Ras-, Rac-, and p38 kinase-dependent pathways in cardiac myocytes","volume":"33","author":"He","year":"1999","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib28","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1161\/CIRCRESAHA.107.150474","article-title":"Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage","volume":"101","author":"Henke","year":"2007","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2009.04.004_bib29","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1042\/CS20060342","article-title":"Angiotensin II signal transduction through the AT1 receptor: novel insights into mechanisms and pathophysiology","volume":"112","author":"Higuchi","year":"2007","journal-title":"Clin. Sci. (Lond)."},{"key":"10.1016\/j.vph.2009.04.004_bib30","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF01076566","article-title":"Tyrosine kinase-mediated signal transduction pathways and the actions of polypeptide growth factors and G-protein-coupled agonists in smooth muscle","volume":"149\u2013150","author":"Hollenberg","year":"1995","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.vph.2009.04.004_bib31","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1080\/10611860601151860","article-title":"Toxicogenomics of drug delivery systems: exploiting delivery system-induced changes in target gene expression to enhance siRNA activity","volume":"15","author":"Hollins","year":"2007","journal-title":"J. Drug Target."},{"issue":"Suppl 1","key":"10.1016\/j.vph.2009.04.004_bib32","doi-asserted-by":"crossref","first-page":"S96","DOI":"10.1093\/bioinformatics\/18.suppl_1.S96","article-title":"Variance stabilization applied to microarray data calibration and to the quantification of differential expression","volume":"18","author":"Huber","year":"2002","journal-title":"Bioinformatics"},{"key":"10.1016\/j.vph.2009.04.004_bib33","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1161\/01.HYP.0000047104.42047.9B","article-title":"Antisense to epidermal growth factor receptor prevents the development of left ventricular hypertrophy","volume":"41","author":"Kagiyama","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib34","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1254\/jphs.FP0060021","article-title":"Epidermal growth factor induces vasoconstriction through the phosphatidylinositol 3-kinase-mediated mitogen-activated protein kinase pathway in hypertensive rats","volume":"101","author":"Kim","year":"2006","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.vph.2009.04.004_bib35","doi-asserted-by":"crossref","first-page":"H1789","DOI":"10.1152\/ajpheart.01118.2006","article-title":"Resistance artery remodeling in deoxycorticosterone acetate\u2013salt hypertension is dependent on vascular inflammation: evidence from m-CSF-deficient mice","volume":"292","author":"Ko","year":"2007","journal-title":"Am. J. Physiol, Heart Circ. Physiol."},{"key":"10.1016\/j.vph.2009.04.004_bib36","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1161\/01.HYP.0000056768.03657.B4","article-title":"Enhancement of intrarenal angiotensinogen in Dahl salt-sensitive rats on high salt diet","volume":"41","author":"Kobori","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib37","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1161\/HYPERTENSIONAHA.107.096289","article-title":"Axl mediates vascular remodeling induced by deoxycorticosterone acetate\u2013salt hypertension","volume":"50","author":"Korshunov","year":"2007","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib38","doi-asserted-by":"crossref","first-page":"8075","DOI":"10.1128\/MCB.19.12.8075","article-title":"Axl\u2013gas6 interaction counteracts E1A-mediated cell growth suppression and proapoptotic activity","volume":"19","author":"Lee","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.vph.2009.04.004_bib39","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1152\/physiolgenomics.00083.2001","article-title":"Renal medullary genes in salt-sensitive hypertension: a chromosomal substitution and cDNA microarray study","volume":"8","author":"Liang","year":"2002","journal-title":"Physiol. Genomics"},{"key":"10.1016\/j.vph.2009.04.004_bib40","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1152\/physiolgenomics.00089.2002","article-title":"Insights into Dahl salt-sensitive hypertension revealed by temporal patterns of renal medullary gene expression","volume":"12","author":"Liang","year":"2003","journal-title":"Physiol. Genomics"},{"key":"10.1016\/j.vph.2009.04.004_bib41","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1126\/science.1061663","article-title":"Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family","volume":"293","author":"Lu","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.vph.2009.04.004_bib42","doi-asserted-by":"crossref","unstructured":"Mancia, G., Zanchetti, A., 2008. Choice of antihypertensive drugs in the European Society of Hypertension\u2013European Society of Cardiology guidelines: specific indications rather than ranking for general usage. J. Hypertens. 26 (2), 164\u2013168.","DOI":"10.1097\/HJH.0b013e3282f52fa8"},{"key":"10.1016\/j.vph.2009.04.004_bib43","doi-asserted-by":"crossref","first-page":"23,285","DOI":"10.1074\/jbc.272.37.23285","article-title":"GAS6 mediates adhesion of cells expressing the receptor tyrosine kinase Axl","volume":"272","author":"McCloskey","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2009.04.004_bib44","doi-asserted-by":"crossref","first-page":"C82","DOI":"10.1152\/ajpcell.00287.2006","article-title":"Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system","volume":"292","author":"Mehta","year":"2007","journal-title":"Am. J. Physiol., Cell Physiol."},{"key":"10.1016\/j.vph.2009.04.004_bib45","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1161\/HYPERTENSIONAHA.107.105395","article-title":"Altered release of cytochrome p450 metabolites of arachidonic acid in renovascular disease","volume":"51","author":"Minuz","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib46","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1681\/ASN.2007121271","article-title":"High perfusion pressure accelerates renal injury in salt-sensitive hypertension","volume":"19","author":"Mori","year":"2008","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.vph.2009.04.004_bib47","doi-asserted-by":"crossref","first-page":"30,149","DOI":"10.1074\/jbc.271.47.30149","article-title":"Calcium\/calmodulin-dependent protein kinase IIalpha mediates activation of mitogen-activated protein kinase and cytosolic phospholipase A2 in norepinephrine-induced arachidonic acid release in rabbit aortic smooth muscle cells","volume":"271","author":"Muthalif","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2009.04.004_bib48","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1161\/01.HYP.35.1.457","article-title":"Contribution of Ras-GTPase GTPase\/MAP kinase and cytochrome P450 metabolites to deoxycorticosterone\u2013salt-induced hypertension","volume":"35","author":"Muthalif","year":"2000","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib49","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1161\/01.HYP.36.4.604","article-title":"Angiotensin II-induced hypertension: contribution of Ras GTPase\/Mitogen-activated protein kinase and cytochrome P450 metabolites","volume":"36","author":"Muthalif","year":"2000","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib50","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1161\/01.HYP.35.1.457","article-title":"Contribution of Ras GTPase\/MAP kinase and cytochrome P450 metabolites to deoxycorticosterone\u2013salt-induced hypertension","volume":"35","author":"Muthalif","year":"2000","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib51","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/S0022-3565(24)39228-6","article-title":"Ras\/mitogen-activated protein kinase mediates norepinephrine-induced phospholipase D activation in rabbit aortic smooth muscle cells by a phosphorylation-dependent mechanism","volume":"293","author":"Muthalif","year":"2000","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.vph.2009.04.004_bib52","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1161\/hy0202.103823","article-title":"Functional significance of activation of calcium\/calmodulin-dependent protein kinase II in angiotensin II-induced vascular hyperplasia and hypertension","volume":"39","author":"Muthalif","year":"2002","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1161\/01.HYP.0000237975.90870.eb","article-title":"Angiotensin II signal transduction through small GTP-binding proteins","volume":"48","author":"Ohtsu","year":"2006","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib54","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1080\/10611860310001636908","article-title":"Toxicogenomics of non-viral vectors for gene therapy: a microarray study of lipofectin- and oligofectamine-induced gene expression changes in human epithelial cells","volume":"11","author":"Omidi","year":"2003","journal-title":"J. Drug Target."},{"key":"10.1016\/j.vph.2009.04.004_bib55","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1080\/10611860500418881","article-title":"Polypropylenimine dendrimer-induced gene expression changes: the effect of complexation with DNA, dendrimer generation and cell type","volume":"13","author":"Omidi","year":"2005","journal-title":"J. Drug Target."},{"key":"10.1016\/j.vph.2009.04.004_bib56","doi-asserted-by":"crossref","first-page":"F100","DOI":"10.1152\/ajprenal.00520.2006","article-title":"Crucial role of Rho-nuclear factor-kappaB axis in angiotensin II-induced renal injury","volume":"293","author":"Ozawa","year":"2007","journal-title":"Am. J. Physiol., Renal Physiol."},{"key":"10.1016\/j.vph.2009.04.004_bib57","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S0006-2952(03)00407-6","article-title":"Messenger RNA expression profiling of genes involved in epidermal growth factor receptor signalling in human cancer cells treated with scanning array-designed antisense oligonucleotides","volume":"66","author":"Petch","year":"2003","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.vph.2009.04.004_bib58","doi-asserted-by":"crossref","first-page":"R435","DOI":"10.1152\/ajpregu.00300.2005","article-title":"Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes","volume":"290","author":"Portik-Dobos","year":"2006","journal-title":"Am. J. Physiol., Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.vph.2009.04.004_bib59","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/jcp.21246","article-title":"Mitogenic signaling pathways induced by G protein-coupled receptors","volume":"213","author":"Rozengurt","year":"2007","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.vph.2009.04.004_bib60","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1111\/j.1523-1755.2005.09908.x","article-title":"The Rho-kinase pathway regulates angiotensin II-induced renal damage","volume":"99","author":"Rup\u00e9rez","year":"2005","journal-title":"Kidney Inter. Suppl."},{"key":"10.1016\/j.vph.2009.04.004_bib61","doi-asserted-by":"crossref","first-page":"C2019","DOI":"10.1152\/ajpcell.1997.272.6.C2019","article-title":"G protein-coupled receptors control vascular smooth muscle cell proliferation via pp60c-src and p21ras","volume":"272","author":"Schieffer","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.vph.2009.04.004_bib62","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/35075603","article-title":"Phagocytosis and clearance of apoptotic cells is mediated by MER","volume":"411","author":"Scott","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.vph.2009.04.004_bib63","doi-asserted-by":"crossref","first-page":"9268","DOI":"10.1074\/jbc.M109221200","article-title":"AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs","volume":"277","author":"Seta","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2009.04.004_bib64","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1161\/01.CIR.101.14.1722","article-title":"Vascular superoxide production and vasomotor function in hypertension induced by deoxycorticosterone acetate\u2013salt","volume":"101","author":"Somers","year":"2000","journal-title":"Circulation"},{"issue":"15","key":"10.1016\/j.vph.2009.04.004_bib65","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.2174\/092986708784638825","article-title":"Farnesyltransferase inhibitors: a detailed chemical view on an elusive biological problem","volume":"15","author":"Sousa","year":"2008","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.vph.2009.04.004_bib66","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1161\/01.HYP.13.2.115","article-title":"Enalapril prevents stroke and kidney dysfunction in salt-loaded stroke-prone spontaneously hypertensive rats","volume":"13","author":"Stier","year":"1989","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib67","doi-asserted-by":"crossref","first-page":"6017","DOI":"10.1074\/jbc.M109107200","article-title":"Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway","volume":"277","author":"Thomas","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2009.04.004_bib68","first-page":"571","article-title":"Improvement of organ damage by a non-depressor dose of imidapril in diabetic spontaneously hypertensive rats","volume":"19","author":"Tomita","year":"2007","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.vph.2009.04.004_bib69","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1097\/00004872-200406000-00015","article-title":"Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells","volume":"22","author":"Touyz","year":"2004","journal-title":"J. Hypertens."},{"issue":"3","key":"10.1016\/j.vph.2009.04.004_bib70","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1080\/10799890802084671","article-title":"Biochemical assay-based selectivity profiling of clinically relevant kinase inhibitors on mutant forms of EGF receptor","volume":"28","author":"Varkondi","year":"2008","journal-title":"J. Recept. Signal Transduct. Res."},{"key":"10.1016\/j.vph.2009.04.004_bib71","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1139\/o96-053","article-title":"Protein kinase C mediation of Ca2+-independent contractions of vascular smooth muscle","volume":"74","author":"Walsh","year":"1996","journal-title":"Biochem. Cell. Biol."},{"key":"10.1016\/j.vph.2009.04.004_bib72","doi-asserted-by":"crossref","first-page":"14,624","DOI":"10.1074\/jbc.275.19.14624","article-title":"Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival","volume":"275","author":"Wang","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2009.04.004_bib73","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1111\/j.1523-1755.2004.00955.x","article-title":"Epidermal growth factor receptor inhibition attenuates early kidney enlargement in experimental diabetes","volume":"66","author":"Wassef","year":"2004","journal-title":"Kidney. Int."},{"key":"10.1016\/j.vph.2009.04.004_bib74","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/S0022-3565(24)37741-9","article-title":"Dissociation of angiotensin II-stimulated activation of mitogen-activated protein kinase kinase from vascular contraction","volume":"286","author":"Watts","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.vph.2009.04.004_bib75","doi-asserted-by":"crossref","first-page":"II 127","DOI":"10.1161\/01.HYP.8.6_Pt_2.II127","article-title":"Definitions and characteristics of sodium sensitivity and blood pressure resistance","volume":"8","author":"Weinberger","year":"1986","journal-title":"Hypertension"},{"issue":"Suppl. 2","key":"10.1016\/j.vph.2009.04.004_bib76","first-page":"29","article-title":"Renal protection in hypertensive patients: selection of antihypertensive therapy","volume":"65","author":"Wenzel","year":"2005","journal-title":"Drugs"},{"key":"10.1016\/j.vph.2009.04.004_bib77","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1161\/HYPERTENSIONAHA.107.099432","article-title":"Hypertension induces somatic cellular senescence in rats and humans by induction of cell cycle inhibitor p16INK4a","volume":"52","author":"Westhoff","year":"2008","journal-title":"Hypertension"},{"issue":"51","key":"10.1016\/j.vph.2009.04.004_bib78","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1016\/j.jacc.2008.03.010","article-title":"The year in hypertension","volume":"51","author":"Williams","year":"2008","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.vph.2009.04.004_bib79","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1161\/01.RES.0000160556.52369.61","article-title":"Identification of hypertension-related genes through an integrated genomic-transcriptomic approach","volume":"96","author":"Yagil","year":"2005","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2009.04.004_bib80","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1002\/cbf.1446","article-title":"Role of Ca2+\/calmodulin-dependent protein kinase II in development of vascular dysfunction in diabetic rats with hypertension","volume":"26","author":"Yousif","year":"2008","journal-title":"Cell. Biochem. Funct."},{"key":"10.1016\/j.vph.2009.04.004_bib81","doi-asserted-by":"crossref","unstructured":"Yousif, M.H., Benter, I.F., Abul, A.H., Abraham, S., Walther, T., Akhtar, S., 2008b. Inhibition of Ras-GTPase signaling by FPTIII ameliorates development of cardiovascular dysfunction in diabetic-hypertensive rats. Vascul Pharmacol. 49, 151\u2013157.","DOI":"10.1016\/j.vph.2008.05.004"},{"key":"10.1016\/j.vph.2009.04.004_bib82","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1161\/01.HYP.0000094220.06020.C8","article-title":"In salt-sensitive hypertension, increased superoxide production is linked to functional upregulation of angiotensin II","volume":"42","author":"Zhou","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.vph.2009.04.004_bib83","doi-asserted-by":"crossref","first-page":"20,989","DOI":"10.1074\/jbc.274.30.20989","article-title":"Distinct calcium-dependent pathways of epidermal growth factor receptor transactivation and PYK2 tyrosine phosphorylation in PC12 cells","volume":"274","author":"Zwick","year":"1999","journal-title":"J. Biol. Chem."}],"container-title":["Vascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189109000469?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189109000469?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T08:27:10Z","timestamp":1739089630000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1537189109000469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8]]},"references-count":83,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2009,8]]}},"alternative-id":["S1537189109000469"],"URL":"https:\/\/doi.org\/10.1016\/j.vph.2009.04.004","relation":{},"ISSN":["1537-1891"],"issn-type":[{"type":"print","value":"1537-1891"}],"subject":[],"published":{"date-parts":[[2009,8]]}}}