{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T22:23:43Z","timestamp":1759530223471,"version":"3.40.5"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004434","name":"University of Florence","doi-asserted-by":"crossref","award":["NISTATEN11"],"award-info":[{"award-number":["NISTATEN11"]}],"id":[{"id":"10.13039\/501100004434","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vascular Pharmacology"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.vph.2015.06.008","type":"journal-article","created":{"date-parts":[[2015,6,23]],"date-time":"2015-06-23T04:49:39Z","timestamp":1435034979000},"page":"19-28","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Protection of coronary endothelial cells from cigarette smoke-induced oxidative stress by a new MnII-containing polyamine-polycarboxilate scavenger of superoxide anion"],"prefix":"10.1016","volume":"75","author":[{"given":"Matteo","family":"Becatti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Boccalini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9828-2082","authenticated-orcid":false,"given":"Alessandro","family":"Pini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Fiorillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Bencini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Bani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Nistri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vph.2015.06.008_bb0005","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/S0140-6736(06)69249-0","article-title":"Tobacco use and risk of myocardial infarction in 52 countries in the INTERHEART study: a case\u2013control study","volume":"368","author":"Teo","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.vph.2015.06.008_bb0010","series-title":"WHO global report: mortality attributable to tobacco","first-page":"1","author":"World Health Organization","year":"2012"},{"key":"10.1016\/j.vph.2015.06.008_bb0015","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1161\/01.CIR.0000085996.95532.FF","article-title":"Cardiovascular risk factors and atherosclerosis in young males: ARMY study (atherosclerosis risk-factors in male youngsters.)","volume":"108","author":"Knoflach","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.vph.2015.06.008_bb0020","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1046\/j.1365-2613.2000.00162.x","article-title":"Cigarette smoking, endothelial injury and cardiovascular disease","volume":"81","author":"Pittilo","year":"2000","journal-title":"Int. J. Exp. Pathol."},{"key":"10.1016\/j.vph.2015.06.008_bb0025","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0033-0620(03)00076-8","article-title":"Oxidative stress and smoking-induced vascular injury","volume":"46","author":"Burke","year":"2003","journal-title":"Prog. Cardiovasc. Dis."},{"key":"10.1016\/j.vph.2015.06.008_bb0030","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1016\/j.jacc.2003.12.047","article-title":"The pathophysiology of cigarette smoking and cardiovascular disease: an update","volume":"43","author":"Ambrose","year":"2004","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.vph.2015.06.008_bb0035","doi-asserted-by":"crossref","first-page":"3128","DOI":"10.2741\/3440","article-title":"Oxidative stress and accelerated vascular aging: implications for cigarette smoking","volume":"14","author":"Csiszar","year":"2009","journal-title":"Front. Biosci."},{"key":"10.1016\/j.vph.2015.06.008_bb0040","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.2174\/138161210792062830","article-title":"Adverse effects of cigarette smoke and induction of oxidative stress in cardiomyocytes and vascular endothelium","volume":"16","author":"Varela-Carver","year":"2010","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.vph.2015.06.008_bb0045","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1161\/ATVBAHA.113.300156","article-title":"Smoking and cardiovascular disease: mechanisms of endothelial dysfunction and early atherogenesis","volume":"34","author":"Messner","year":"2014","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.vph.2015.06.008_bb0050","first-page":"68612","article-title":"Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite","author":"Pryor","year":"1993","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.vph.2015.06.008_bb0055","doi-asserted-by":"crossref","first-page":"276","DOI":"10.2174\/157016107782023406","article-title":"Structural and functional alteration of blood vessels caused by cigarette smoking: an overview of molecular mechanisms","volume":"5","author":"Rahman","year":"2007","journal-title":"Curr. Vasc. Pharmacol."},{"key":"10.1016\/j.vph.2015.06.008_bb0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejphar.2010.09.042","article-title":"Nitric oxide-mediated blood flow regulation as affected by smoking and nicotine","volume":"649","author":"Toda","year":"2010","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.vph.2015.06.008_bb0065","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/nrcardio.2013.8","article-title":"The biology behind the atherothrombotic effects of cigarette smoke","volume":"10","author":"Csordas","year":"2013","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.vph.2015.06.008_bb0070","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1124\/jpet.103.064154","article-title":"A newly identified role for superoxide in inflammatory pain","volume":"309","author":"Wang","year":"2004","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.vph.2015.06.008_bb0075","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1038\/nrm1763","article-title":"Radical medicine: treating ageing to cure disease","volume":"6","author":"Finkel","year":"2005","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.vph.2015.06.008_bb0080","doi-asserted-by":"crossref","first-page":"7273","DOI":"10.1021\/jm901298x","article-title":"A novel manganese complex effective as superoxide anion scavenger and therapeutic agent against cell and tissue oxidative injury","volume":"52","author":"Failli","year":"2009","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.vph.2015.06.008_bb0085","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1016\/j.freeradbiomed.2010.02.041","article-title":"Suppression of allergen-induced respiratory dysfunction and airway inflammation in sensitized guinea pigs by Mn(II)(Me(2)DO2A), a novel superoxide scavenger compound","volume":"48","author":"Cinci","year":"2010","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.vph.2015.06.008_bb0090","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/905360","article-title":"Therapeutic effects of the superoxide dismutase mimetic compound MnIIMe2DO2A on experimental articular pain in rats","author":"Di Cesare","year":"2013","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.vph.2015.06.008_bb0095","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3109\/10715762.2014.979168","article-title":"A new low molecular weight, MnII-containing scavenger of superoxide anion protects cardiac muscle cells from hypoxia\/reoxygenation injury","volume":"49","author":"Nistri","year":"2015","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.vph.2015.06.008_bb0100","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0010-8545(99)00237-4","article-title":"Thermodynamics and structural properties of Gd(III) complexes with polyamino\u2013polycarboxylic ligands: basic compound for the development of MRI contrast agents","volume":"24","author":"Bianchi","year":"2000","journal-title":"Coord. Chem. Rev."},{"year":"2001","series-title":"The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging","author":"Merbach","key":"10.1016\/j.vph.2015.06.008_bb0105"},{"key":"10.1016\/j.vph.2015.06.008_bb0110","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1124\/jpet.111.179978","article-title":"Cerium oxide nanoparticles inhibits oxidative stress and nuclear factor-KB activation in H9C2 cardiomyocytes exposed to cigarette smoke extract","volume":"338","author":"Niu","year":"2011","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.vph.2015.06.008_bb0115","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1096\/fj.01-0569fje","article-title":"Relaxin up-regulates inducible nitric oxide synthase expression and nitric oxide generation in rat coronary endothelial cells","volume":"16","author":"Failli","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/j.vph.2015.06.008_bb0120","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/jcmm.12206","article-title":"SIRT1 regulates MAPK pathways in vitiligo skin: insight into the molecular pathways of cell survival","volume":"18","author":"Becatti","year":"2014","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.vph.2015.06.008_bb0125","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1007\/s00018-012-0925-5","article-title":"SIRT1 modulates MAPK pathways in ischemic-reperfused cardiomyocytes","volume":"69","author":"Becatti","year":"2012","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.vph.2015.06.008_bb0130","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.atherosclerosis.2013.09.030","article-title":"Platelet and leukocyte ROS production and lipoperoxidation are associated with high platelet reactivity in Non-ST elevation myocardial infarction (NSTEMI) patients on dual antiplatelet treatment","volume":"231","author":"Becatti","year":"2013","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.vph.2015.06.008_bb0135","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1179\/1351000213Y.0000000045","article-title":"Altered redox status in the blood of psoriatic patients: involvement of NADPH oxidase and role of anti-TNF-\u03b1 therapy","volume":"18","author":"Barygina","year":"2013","journal-title":"Redox Rep."},{"key":"10.1016\/j.vph.2015.06.008_bb0140","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1161\/01.ATV.21.5.863","article-title":"Cadmium accumulation in aortas of smokers","volume":"21","author":"Abu-Hayyeh","year":"2001","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.vph.2015.06.008_bb0145","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.2174\/092986707781058959","article-title":"Smoking, oxidative stress and cardiovascular diseases\u2014do anti-oxidative therapies fail?","volume":"14","author":"Bernhard","year":"2007","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.vph.2015.06.008_bb0150","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1096\/fj.03-0312fje","article-title":"Disruption of vascular endothelial homeostasis by tobacco smoke: impact on atherosclerosis","volume":"17","author":"Bernhard","year":"2003","journal-title":"FASEB J."},{"key":"10.1016\/j.vph.2015.06.008_bb0155","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/cvr\/cvr165","article-title":"Cigarette smoke extract induces prolonged endoplasmic reticulum stress and autophagic cell death in human umbilical vein endothelial cells","volume":"92","author":"Csordas","year":"2011","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.vph.2015.06.008_bb0160","doi-asserted-by":"crossref","first-page":"e424","DOI":"10.1038\/cddis.2012.162","article-title":"Apoptosis and necrosis: two different outcomes of cigarette smoke condensate-induced endothelial cell death","volume":"3","author":"Messner","year":"2012","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.vph.2015.06.008_bb0165","doi-asserted-by":"crossref","first-page":"386","DOI":"10.3109\/10715762.2013.780286","article-title":"Recombinant PTD-Cu\/Zn SOD attenuates hypoxia-reoxygenation injury in cardiomyocytes","volume":"47","author":"Liu","year":"2013","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.vph.2015.06.008_bb0170","doi-asserted-by":"crossref","first-page":"4228","DOI":"10.1002\/anie.200905936","article-title":"Striking inflammation from both sides: manganese(II) pentaazamacrocyclic SOD mimics act also as nitric oxide dismutases: a single-cell study","volume":"49","author":"Filipovi\u0107","year":"2010","journal-title":"Angew. Chem. Int. Ed. Engl."}],"container-title":["Vascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189115001391?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189115001391?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T11:08:43Z","timestamp":1589540923000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1537189115001391"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":34,"alternative-id":["S1537189115001391"],"URL":"https:\/\/doi.org\/10.1016\/j.vph.2015.06.008","relation":{},"ISSN":["1537-1891"],"issn-type":[{"type":"print","value":"1537-1891"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protection of coronary endothelial cells from cigarette smoke-induced oxidative stress by a new MnII-containing polyamine-polycarboxilate scavenger of superoxide anion","name":"articletitle","label":"Article Title"},{"value":"Vascular Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vph.2015.06.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}