{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T21:50:50Z","timestamp":1789077050966,"version":"build-2803163510"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81070190"],"award-info":[{"award-number":["81070190"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81072634"],"award-info":[{"award-number":["81072634"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81373413"],"award-info":[{"award-number":["81373413"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81470458"],"award-info":[{"award-number":["81470458"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People&apos;s Republic of China","doi-asserted-by":"publisher","award":["2013YGYL008"],"award-info":[{"award-number":["2013YGYL008"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People&apos;s Republic of China","doi-asserted-by":"publisher","award":["NCET-10-0409"],"award-info":[{"award-number":["NCET-10-0409"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","award":["2011zx09102-004-001"],"award-info":[{"award-number":["2011zx09102-004-001"]}],"id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","award":["2013zx09103-001-020"],"award-info":[{"award-number":["2013zx09103-001-020"]}],"id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vascular Pharmacology"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.vph.2015.07.004","type":"journal-article","created":{"date-parts":[[2015,7,15]],"date-time":"2015-07-15T23:29:15Z","timestamp":1437002955000},"page":"141-152","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":94,"special_numbering":"C","title":["Salidroside improves endothelial function and alleviates atherosclerosis by activating a mitochondria-related AMPK\/PI3K\/Akt\/eNOS pathway"],"prefix":"10.1016","volume":"72","author":[{"given":"Sha-Sha","family":"Xing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Yan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang-Yang","family":"Chi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang-Li","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang-Jie","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You-Zhi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cun-tai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Hui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Sheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vph.2015.07.004_bb0005","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1161\/01.CIR.0000028581.07992.56","article-title":"Endothelial function: a barometer for cardiovascular risk?","volume":"106","author":"Vita","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.vph.2015.07.004_bb0010","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1038\/nature01323","article-title":"Inflammation in atherosclerosis","volume":"420","author":"Libby","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.vph.2015.07.004_bb0015","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1038\/nm1102-1235","article-title":"The macrophage foam cell as a target for therapeutic intervention","volume":"8","author":"Li","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.vph.2015.07.004_bb0020","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1021\/np200555s","article-title":"Salidroside protects human erythrocytes against hydrogen peroxide-induced apoptosis","volume":"75","author":"Qian","year":"2012","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.vph.2015.07.004_bb0025","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1016\/j.foodchem.2012.04.026","article-title":"Protection of curcumin against fructose-induced hyperuricaemia and renal endothelial dysfunction involves NO-mediated JAK-STAT signalling in rats","volume":"134","author":"Zhang","year":"2012","journal-title":"Food Chem."},{"issue":"12","key":"10.1016\/j.vph.2015.07.004_bb0030","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1089\/ars.2013.5600","article-title":"Binding to WGR domain by Salidroside activates PARP1 and protects hematopoietic stem cells from oxidative stress","volume":"20","author":"Li","year":"2014","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.vph.2015.07.004_bb0035","first-page":"607508","article-title":"Salidroside decreases atherosclerotic plaque formation in low-density lipoprotein receptor-deficient mice","author":"Zhang","year":"2012","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.vph.2015.07.004_bb0040","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1161\/CIRCRESAHA.109.201590","article-title":"Activation and signaling by the AMP-activated protein kinase in endothelial cells","volume":"105","author":"Fisslthaler","year":"2009","journal-title":"Circ. Res."},{"issue":"Suppl. 4","key":"10.1016\/j.vph.2015.07.004_bb0045","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1038\/ijo.2008.116","article-title":"AMPK: a key regulator of energy balance in the single cell and the whole organism","volume":"32","author":"Hardie","year":"2008","journal-title":"Int. J. Obes. (Lond)"},{"key":"10.1016\/j.vph.2015.07.004_bb0050","doi-asserted-by":"crossref","first-page":"3329","DOI":"10.1073\/pnas.0308061100","article-title":"The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress","volume":"101","author":"Shaw","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.vph.2015.07.004_bb0055","doi-asserted-by":"crossref","first-page":"496","DOI":"10.2337\/diabetes.55.02.06.db05-1064","article-title":"Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase","volume":"55","author":"Davis","year":"2006","journal-title":"Diabetes"},{"key":"10.1016\/j.vph.2015.07.004_bb0060","doi-asserted-by":"crossref","first-page":"45021","DOI":"10.1074\/jbc.M307878200","article-title":"Adiponectin stimulates production of nitric oxide in vascular endothelial cells","volume":"278","author":"Chen","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2015.07.004_bb0065","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.febslet.2004.07.078","article-title":"Thrombin and histamine stimulate endothelial nitric-oxide synthase phosphorylation at Ser1177 via an AMPK mediated pathway independent of PI3K-Akt","volume":"573","author":"Thors","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.vph.2015.07.004_bb0070","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1016\/j.bbamcr.2008.07.003","article-title":"Mechanism of thrombin mediated eNOS phosphorylation in endothelial cells is dependent on ATP levels after stimulation","volume":"1783","author":"Thors","year":"2008","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.vph.2015.07.004_bb0075","doi-asserted-by":"crossref","first-page":"20351","DOI":"10.1074\/jbc.M702182200","article-title":"Agonist-modulated regulation of AMP-activated protein kinase (AMPK) in endothelial cells. Evidence for an AMPK\u2192Rac1\u2192Akt\u2192endothelial nitric-oxide synthase pathway","volume":"282","author":"Levine","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2015.07.004_bb0080","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0014-5793(98)01705-0","article-title":"AMP-activated protein kinase phosphorylation of endothelial NO synthase","volume":"443","author":"Chen","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1016\/j.vph.2015.07.004_bb0085","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1074\/jbc.M310389200","article-title":"Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells","volume":"279","author":"Ouchi","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2015.07.004_bb0090","doi-asserted-by":"crossref","first-page":"31000","DOI":"10.1074\/jbc.M300643200","article-title":"AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress","volume":"278","author":"Nagata","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2015.07.004_bb0095","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1161\/ATVBAHA.112.300560","article-title":"Depolarization of mitochondria in endothelial cells promotes cerebral artery vasodilation by activation of nitric oxide synthase","volume":"33","author":"Katakam","year":"2013","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.vph.2015.07.004_bb0100","doi-asserted-by":"crossref","first-page":"R289","DOI":"10.1152\/ajpregu.90656.2008","article-title":"Impaired mitochondria-dependent vasodilation in cerebral arteries of Zucker obese rats with insulin resistance","volume":"296","author":"Katakam","year":"2009","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.vph.2015.07.004_bb0105","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s11357-012-9394-x","article-title":"Rejuvenating activity of salidroside (SDS): dietary intake of SDS enhances the immune response of aged rats","volume":"35","author":"Lu","year":"2013","journal-title":"Age (Dordr.)"},{"key":"10.1016\/j.vph.2015.07.004_bb0110","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0021-9150(87)90202-4","article-title":"Quantitative assessment of atherosclerotic lesions in mice","volume":"68","author":"Paigen","year":"1987","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.vph.2015.07.004_bb0115","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1161\/CIRCULATIONAHA.109.872663","article-title":"Impaired fibrillin-1 function promotes features of plaque instability in apolipoprotein E-deficient mice","volume":"120","author":"Van Herck","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.vph.2015.07.004_bb0120","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1172\/JCI107470","article-title":"Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria","volume":"52","author":"Jaffe","year":"1973","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.vph.2015.07.004_bb0125","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1182\/blood-2009-04-216432","article-title":"Induction of nitric oxide by erythropoietin is mediated by the {beta} common receptor and requires interaction with VEGF receptor 2","volume":"115","author":"Sautina","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.vph.2015.07.004_bb0130","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.cardiores.2005.10.014","article-title":"Apurinic\/apyrimidinic endonuclease1\/redox factor-1 inhibits monocyte adhesion in endothelial cells","volume":"69","author":"Kim","year":"2006","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.vph.2015.07.004_bb0135","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1093\/gerona\/glr228","article-title":"Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment","volume":"67","author":"Csiszar","year":"2012","journal-title":"J. Gerontol. A: Biol. Med. Sci."},{"key":"10.1016\/j.vph.2015.07.004_bb0140","doi-asserted-by":"crossref","first-page":"7217","DOI":"10.1073\/pnas.0610068104","article-title":"Resveratrol stimulates AMP kinase activity in neurons","volume":"104","author":"Dasgupta","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.vph.2015.07.004_bb0145","doi-asserted-by":"crossref","first-page":"4480","DOI":"10.1021\/bi00232a015","article-title":"J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential","volume":"30","author":"Reers","year":"1991","journal-title":"Biochemistry"},{"key":"10.1016\/j.vph.2015.07.004_bb0150","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1194\/jlr.M035907","article-title":"Ginsenoside Rb1 reduces fatty liver by activating AMP-activated protein kinase in obese rats","volume":"54","author":"Shen","year":"2013","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.vph.2015.07.004_bb0155","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/21218","article-title":"Regulation of endothelium-derived nitric oxide production by the protein kinase Akt","volume":"399","author":"Fulton","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.vph.2015.07.004_bb0160","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.tem.2009.03.005","article-title":"eNOS, metabolic syndrome and cardiovascular disease","volume":"20","author":"Huang","year":"2009","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.vph.2015.07.004_bb0165","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.yjmcc.2006.05.023","article-title":"Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation","volume":"42","author":"Mount","year":"2007","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.vph.2015.07.004_bb0170","doi-asserted-by":"crossref","first-page":"31629","DOI":"10.1074\/jbc.M212831200","article-title":"Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells","volume":"278","author":"Morrow","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2015.07.004_bb0175","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/21224","article-title":"Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation","volume":"399","author":"Dimmeler","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.vph.2015.07.004_bb0180","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1161\/CIRCRESAHA.108.178467","article-title":"An ezrin\/calpain\/PI3K\/AMPK\/eNOSs1179 signaling cascade mediating VEGF-dependent endothelial nitric oxide production","volume":"104","author":"Youn","year":"2009","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2015.07.004_bb0185","doi-asserted-by":"crossref","first-page":"32207","DOI":"10.1074\/jbc.M606357200","article-title":"Dissecting the role of 5\u2032-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase","volume":"281","author":"Suter","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2015.07.004_bb0190","first-page":"417","article-title":"Mitochondria: structure and function","volume":"147","author":"Sherratt","year":"1991","journal-title":"Rev. Neurol."},{"key":"10.1016\/j.vph.2015.07.004_bb0195","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.molmed.2008.09.007","article-title":"AMPK: a metabolic gauge regulating whole-body energy homeostasis","volume":"14","author":"Lage","year":"2008","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.vph.2015.07.004_bb0200","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1161\/01.STR.0000226901.34927.10","article-title":"Inflammation and atherosclerosis: novel insights into plaque formation and destabilization","volume":"37","author":"Stoll","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.vph.2015.07.004_bb0205","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/00041433-200404000-00007","article-title":"The role of chemokines in atherosclerosis: recent evidence from experimental models and population genetics","volume":"15","author":"Bursill","year":"2004","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.vph.2015.07.004_bb0210","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0031-6997(25)06663-3","article-title":"Nitric oxide: physiology, pathophysiology, and pharmacology","volume":"43","author":"Moncada","year":"1991","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.vph.2015.07.004_bb0215","doi-asserted-by":"crossref","first-page":"2494","DOI":"10.1161\/01.CIR.97.25.2494","article-title":"Reduced endothelial nitric oxide synthase expression and production in human atherosclerosis","volume":"97","author":"Oemar","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.vph.2015.07.004_bb0220","doi-asserted-by":"crossref","first-page":"E68","DOI":"10.1161\/hh1101.092677","article-title":"Phosphorylation of Thr(495) regulates Ca2+\/calmodulin-dependent endothelial nitric oxide synthase activity","volume":"88","author":"Fleming","year":"2001","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2015.07.004_bb0225","first-page":"679635","article-title":"Salidroside improves homocysteine-induced endothelial dysfunction by reducing oxidative stress","author":"Leung","year":"2013","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.vph.2015.07.004_bb0230","doi-asserted-by":"crossref","first-page":"3584","DOI":"10.1210\/en.2008-0921","article-title":"Leptin-stimulated endothelial nitric-oxide synthase via an adenosine 5\u2032-monophosphate-activated protein kinase\/Akt signaling pathway is attenuated by interaction with C-reactive protein","volume":"150","author":"Procopio","year":"2009","journal-title":"Endocrinology"},{"key":"10.1016\/j.vph.2015.07.004_bb0235","doi-asserted-by":"crossref","first-page":"39422","DOI":"10.1074\/jbc.M305371200","article-title":"Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart","volume":"278","author":"Kovacic","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2015.07.004_bb0240","doi-asserted-by":"crossref","first-page":"H2472","DOI":"10.1152\/ajpheart.01206.2005","article-title":"Activation of cardiac AMP-activated protein kinase by LKB1 expression or chemical hypoxia is blunted by increased Akt activity","volume":"290","author":"Soltys","year":"2006","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.vph.2015.07.004_bb0245","doi-asserted-by":"crossref","first-page":"5335","DOI":"10.1074\/jbc.M506850200","article-title":"Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485\/491","volume":"281","author":"Horman","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2015.07.004_bb0250","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1016\/j.cub.2003.10.031","article-title":"LKB1 is the upstream kinase in the AMP-activated protein kinase cascade","volume":"13","author":"Woods","year":"2003","journal-title":"Curr. Biol."},{"key":"10.1016\/j.vph.2015.07.004_bb0255","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1080\/1028602042000325645","article-title":"The effect of salidroside on cell damage induced by glutamate and intracellular free calcium in PC12 cells","volume":"8","author":"Cao","year":"2006","journal-title":"J. Asian Nat. Prod. Res."},{"key":"10.1016\/j.vph.2015.07.004_bb0260","doi-asserted-by":"crossref","first-page":"2855","DOI":"10.1242\/jcs.03062","article-title":"Nitric oxide and mitochondrial biogenesis","volume":"119","author":"Nisoli","year":"2006","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.vph.2015.07.004_bb0265","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1089\/ars.2008.2331","article-title":"Mitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function","volume":"11","author":"Stowe","year":"2009","journal-title":"Antioxid. Redox Signal."}],"container-title":["Vascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189115001536?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189115001536?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T07:47:00Z","timestamp":1748504820000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1537189115001536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":53,"alternative-id":["S1537189115001536"],"URL":"https:\/\/doi.org\/10.1016\/j.vph.2015.07.004","relation":{},"ISSN":["1537-1891"],"issn-type":[{"value":"1537-1891","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Salidroside improves endothelial function and alleviates atherosclerosis by activating a mitochondria-related AMPK\/PI3K\/Akt\/eNOS pathway","name":"articletitle","label":"Article Title"},{"value":"Vascular Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vph.2015.07.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}