{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T05:48:28Z","timestamp":1780379308862,"version":"3.54.1"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["K01HL145324"],"award-info":[{"award-number":["K01HL145324"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["RO1HL132574-01A1"],"award-info":[{"award-number":["RO1HL132574-01A1"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vascular Pharmacology"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.vph.2022.107002","type":"journal-article","created":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T12:11:03Z","timestamp":1653394263000},"page":"107002","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Mediterranean G6PD variant rats are protected from Angiotensin II-induced hypertension and kidney damage, but not from inflammation and arterial stiffness"],"prefix":"10.1016","volume":"145","author":[{"given":"Shun","family":"Matsumura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"D'Addiaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orazio J.","family":"Slivano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"De Miguel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Stier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakhee","family":"Gupte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph M.","family":"Miano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachin A.","family":"Gupte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vph.2022.107002_bb0005","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/prot.20776","article-title":"Managing and mining protein crystallization data","volume":"62","author":"Amin","year":"2006","journal-title":"Proteins."},{"key":"10.1016\/j.vph.2022.107002_bb0010","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1161\/CIR.0000000000000659","article-title":"American Heart Association Council on E, prevention statistics C and stroke statistics S. heart disease and stroke Statistics-2019 update: a report from the American Heart Association","volume":"139","author":"Benjamin","year":"2019","journal-title":"Circulation."},{"key":"10.1016\/j.vph.2022.107002_bb0015","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1161\/CIRCRESAHA.117.311819","article-title":"Lactate promotes synthetic phenotype in vascular smooth muscle cells","volume":"121","author":"Yang","year":"2017","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2022.107002_bb0020","doi-asserted-by":"crossref","first-page":"H613","DOI":"10.1152\/ajpheart.00220.2020","article-title":"Metabolism of vascular smooth muscle cells in vascular diseases","volume":"319","author":"Shi","year":"2020","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.vph.2022.107002_bb0025","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1161\/CIRCRESAHA.115.306361","article-title":"Vascular smooth muscle cells in atherosclerosis","volume":"118","author":"Bennett","year":"2016","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2022.107002_bb0030","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1161\/01.RES.0000243584.45145.3f","article-title":"Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms","volume":"99","author":"Stenmark","year":"2006","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2022.107002_bb0035","first-page":"L287","article-title":"Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension","volume":"308","author":"Chettimada","year":"2015","journal-title":"Am. J. Phys. Lung Cell. Mol. Phys."},{"key":"10.1016\/j.vph.2022.107002_bb0040","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0140-6736(08)60073-2","article-title":"Glucose-6-phosphate dehydrogenase deficiency","volume":"371","author":"Cappellini","year":"2008","journal-title":"Lancet."},{"key":"10.1016\/j.vph.2022.107002_bb0045","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1182\/blood.V91.2.706","article-title":"Mortality in a cohort of men expressing the glucose-6-phosphate dehydrogenase deficiency","volume":"91","author":"Cocco","year":"1998","journal-title":"Blood."},{"key":"10.1016\/j.vph.2022.107002_bb0050","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/s10545-008-0704-5","article-title":"Glucose-6-phosphate dehydrogenase deficiency protects against coronary heart disease","volume":"31","author":"Meloni","year":"2008","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.vph.2022.107002_bb0055","first-page":"35","article-title":"Associations between red cell glucose-6-phosphate dehydrogenase variants and vascular diseases","volume":"19","author":"Long","year":"1967","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.vph.2022.107002_bb0060","first-page":"231","article-title":"Relationship between high-sensitivity C-reactive protein serum levels and the severity of coronary artery stenosis in patients with coronary artery disease","volume":"12","author":"Seyedian","year":"2016","journal-title":"ARYA Atheroscler."},{"key":"10.1016\/j.vph.2022.107002_bb0065","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s12933-016-0397-2","article-title":"Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway","volume":"15","author":"Peiro","year":"2016","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.vph.2022.107002_bb0070","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.7150\/ijms.6776","article-title":"Glucose-6-phosphate dehydrogenase deficiency and diabetes mellitus with severe retinal complications in a Sardinian population, Italy","volume":"10","author":"Pinna","year":"2013","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.vph.2022.107002_bb0075","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21207474","article-title":"Glucose-6-phosphate dehydrogenase deficiency activates endothelial cell and leukocyte adhesion mediated via the TGFbeta\/NADPH oxidases\/ROS signaling pathway","volume":"21","author":"Parsanathan","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.vph.2022.107002_bb0080","doi-asserted-by":"crossref","first-page":"144","DOI":"10.14503\/THIJ-16-6052","article-title":"Glucose-6-phosphate dehydrogenase deficiency is associated with cardiovascular disease in U.S. military centers","volume":"45","author":"Thomas","year":"2018","journal-title":"Tex. Heart Inst. J."},{"key":"10.1016\/j.vph.2022.107002_bb0085","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.atherosclerosis.2019.01.027","article-title":"Glucose-6-phosphate dehydrogenase deficiency and risk of cardiovascular disease: a propensity score-matched study","volume":"282","author":"Pes","year":"2019","journal-title":"Atherosclerosis."},{"key":"10.1016\/j.vph.2022.107002_bb0090","first-page":"697","article-title":"Monoclonality of smooth muscle cells in human atherosclerosis","volume":"151","author":"Murry","year":"1997","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.vph.2022.107002_bb0095","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1161\/HYPERTENSIONAHA.120.14772","article-title":"CRISPR-mediated single nucleotide polymorphism modeling in rats reveals insight into reduced cardiovascular risk associated with Mediterranean G6PD variant","volume":"76","author":"Kitagawa","year":"2020","journal-title":"Hypertension."},{"key":"10.1016\/j.vph.2022.107002_bb0100","first-page":"C82","article-title":"Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system","volume":"292","author":"Mehta","year":"2007","journal-title":"Am. J. Phys. Cell Phys."},{"key":"10.1016\/j.vph.2022.107002_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2021.111259","article-title":"Angiotensin receptors in the kidney and vasculature in hypertension and kidney disease","volume":"529","author":"Rianto","year":"2021","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.vph.2022.107002_bb0110","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1161\/01.HYP.0000120971.49659.6a","article-title":"Role of pressure in angiotensin II-induced renal injury: chronic servo-control of renal perfusion pressure in rats","volume":"43","author":"Mori","year":"2004","journal-title":"Hypertension."},{"key":"10.1016\/j.vph.2022.107002_bb0115","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1161\/CIRCRESAHA.116.303697","article-title":"Inflammation, immunity, and hypertensive end-organ damage","volume":"116","author":"McMaster","year":"2015","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2022.107002_bb0120","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1161\/CIRCRESAHA.118.313207","article-title":"A novel angiotensin II-induced Long noncoding RNA giver regulates oxidative stress, inflammation, and proliferation in vascular smooth muscle cells","volume":"123","author":"Das","year":"2018","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2022.107002_bb0125","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0031-6997(25)07139-X","article-title":"Vascular smooth muscle. I. Normal structure, pathology, biochemistry, and biophysics","volume":"20","author":"Somlyo","year":"1968","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.vph.2022.107002_bb0130","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1096\/fasebj.8.2.8119488","article-title":"Glucose-6-phosphate dehydrogenase: a \u201chousekeeping\u201d enzyme subject to tissue-specific regulation by hormones, nutrients, and oxidant stress","volume":"8","author":"Kletzien","year":"1994","journal-title":"FASEB J."},{"key":"10.1016\/j.vph.2022.107002_bb0135","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1097\/RUQ.0b013e3181817c3f","article-title":"Carotid Doppler: low velocity as a sign of significant disease","volume":"24","author":"Horrow","year":"2008","journal-title":"Ultrasound Q."},{"key":"10.1016\/j.vph.2022.107002_bb0140","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1038\/nrcardio.2017.155","article-title":"Arterial stiffness as a risk factor for clinical hypertension","volume":"15","author":"Safar","year":"2018","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.vph.2022.107002_bb0145","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1161\/ATVBAHA.116.308563","article-title":"Killing me Unsoftly: causes and mechanisms of arterial stiffness","volume":"37","author":"Lyle","year":"2017","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.vph.2022.107002_bb0150","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/cvr\/cvs135","article-title":"The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles","volume":"95","author":"Lacolley","year":"2012","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.vph.2022.107002_bb0155","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3389\/fphys.2012.00469","article-title":"The regulation and function of the striated muscle activator of rho signaling (STARS) protein","volume":"3","author":"Wallace","year":"2012","journal-title":"Front. Physiol."},{"key":"10.1016\/j.vph.2022.107002_bb0160","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1161\/HYPERTENSIONAHA.115.06123","article-title":"Origin of matrix-producing cells that contribute to aortic fibrosis in hypertension","volume":"67","author":"Wu","year":"2016","journal-title":"Hypertension."},{"key":"10.1016\/j.vph.2022.107002_bb0165","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1161\/01.RES.84.6.695","article-title":"Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-kappa B transcription factors","volume":"84","author":"Han","year":"1999","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2022.107002_bb0170","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1074\/jbc.M111.302224","article-title":"Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cells","volume":"287","author":"Nanda","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2022.107002_bb0175","doi-asserted-by":"crossref","first-page":"H13","DOI":"10.1152\/ajpheart.00629.2004","article-title":"Cytosolic NADPH may regulate differences in basal Nox oxidase-derived superoxide generation in bovine coronary and pulmonary arteries","volume":"288","author":"Gupte","year":"2005","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.vph.2022.107002_bb0180","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1161\/CIRCRESAHA.109.216036","article-title":"Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium\/calmodulin-dependent, rac-1-independent pathways in human endothelial cells","volume":"106","author":"Montezano","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2022.107002_bb0185","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/nm1545","article-title":"Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity","volume":"13","author":"Leopold","year":"2007","journal-title":"Nat. Med."},{"key":"10.1016\/j.vph.2022.107002_bb0190","doi-asserted-by":"crossref","first-page":"H153","DOI":"10.1152\/ajpheart.01142.2008","article-title":"Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH","volume":"297","author":"Serpillon","year":"2009","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.vph.2022.107002_bb0195","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.freeradbiomed.2009.01.028","article-title":"Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa\/fa, rat liver","volume":"47","author":"Gupte","year":"2009","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.vph.2022.107002_bb0200","doi-asserted-by":"crossref","first-page":"8977","DOI":"10.1074\/jbc.M110.193821","article-title":"Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4","volume":"286","author":"Spencer","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2022.107002_bb0205","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1128\/MCB.01260-12","article-title":"Macrophage glucose-6-phosphate dehydrogenase stimulates proinflammatory responses with oxidative stress","volume":"33","author":"Ham","year":"2013","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.vph.2022.107002_bb0210","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.2337\/db16-0060","article-title":"Glucose-6-phosphate dehydrogenase deficiency improves insulin resistance with reduced adipose tissue inflammation in obesity","volume":"65","author":"Ham","year":"2016","journal-title":"Diabetes."},{"key":"10.1016\/j.vph.2022.107002_bb0215","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1161\/CIRCULATIONAHA.104.499095","article-title":"Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II","volume":"112","author":"Matsui","year":"2005","journal-title":"Circulation."},{"key":"10.1016\/j.vph.2022.107002_bb0220","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1136\/bmj.283.6303.1355","article-title":"Evidence for a raised concentration of a circulating sodium transport inhibitor in essential hypertension","volume":"283","author":"MacGregor","year":"1981","journal-title":"Br. Med. J. (Clin. Res. Ed.)"},{"key":"10.1016\/j.vph.2022.107002_bb0225","doi-asserted-by":"crossref","first-page":"5529256","DOI":"10.1155\/2021\/5529256","article-title":"The controversial role of Glucose-6-phosphate dehydrogenase deficiency on cardiovascular disease: a narrative review","volume":"2021","author":"Dore","year":"2021","journal-title":"Oxidative Med. Cell. Longev."},{"key":"10.1016\/j.vph.2022.107002_bb0230","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s40885-018-0102-8","article-title":"Arterial stiffness and hypertension","volume":"24","author":"Oh","year":"2018","journal-title":"Clin Hypertens."},{"key":"10.1016\/j.vph.2022.107002_bb0235","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1161\/ATVBAHA.107.145862","article-title":"Cooperation of SRC-1 and p300 with NF-kappaB and CREB in angiotensin II-induced IL-6 expression in vascular smooth muscle cells","volume":"27","author":"Sahar","year":"2007","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.vph.2022.107002_bb0240","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1161\/CIRCRESAHA.120.318805","article-title":"Immunometabolic endothelial phenotypes: integrating inflammation and glucose metabolism","volume":"129","author":"Xiao","year":"2021","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2022.107002_bb0245","doi-asserted-by":"crossref","first-page":"19770","DOI":"10.1074\/jbc.M006266200","article-title":"Phosphorylation and regulation of G-protein-activated phospholipase C-beta 3 by cGMP-dependent protein kinases","volume":"276","author":"Xia","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vph.2022.107002_bb0250","doi-asserted-by":"crossref","first-page":"H904","DOI":"10.1152\/ajpheart.00335.2016","article-title":"Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and -independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency","volume":"311","author":"Chettimada","year":"2016","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.vph.2022.107002_bb0255","first-page":"3","article-title":"Myocardin in biology and disease","volume":"29","author":"Miano","year":"2015","journal-title":"J. Biomed. Res."},{"key":"10.1016\/j.vph.2022.107002_bb0260","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1161\/01.ATV.0000205850.49390.3b","article-title":"Glucose-6-phosphate dehydrogenase deficiency decreases vascular superoxide and atherosclerotic lesions in apolipoprotein E(\u2212\/\u2212) mice","volume":"26","author":"Matsui","year":"2006","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.vph.2022.107002_bb0265","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1161\/01.ATV.0000046231.17365.9D","article-title":"Functional interplay between angiotensin II and nitric oxide: cyclic GMP as a key mediator","volume":"23","author":"Yan","year":"2003","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.vph.2022.107002_bb0270","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1161\/ATVBAHA.107.161349","article-title":"GIT1 mediates HDAC5 activation by angiotensin II in vascular smooth muscle cells","volume":"28","author":"Pang","year":"2008","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.vph.2022.107002_bb0275","doi-asserted-by":"crossref","first-page":"H999","DOI":"10.1152\/ajpheart.00488.2020","article-title":"G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases","volume":"320","author":"Dhagia","year":"2021","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.vph.2022.107002_bb0280","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.cell.2007.06.044","article-title":"Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice","volume":"130","author":"Rajasekaran","year":"2007","journal-title":"Cell."},{"key":"10.1016\/j.vph.2022.107002_bb0285","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1161\/CIRCHEARTFAILURE.112.969576","article-title":"Glucose 6-phosphate dehydrogenase deficiency increases redox stress and moderately accelerates the development of heart failure","volume":"6","author":"Hecker","year":"2013","journal-title":"Circ. Heart Fail."}],"container-title":["Vascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189122000519?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189122000519?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T01:21:24Z","timestamp":1761528084000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1537189122000519"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":57,"alternative-id":["S1537189122000519"],"URL":"https:\/\/doi.org\/10.1016\/j.vph.2022.107002","relation":{},"ISSN":["1537-1891"],"issn-type":[{"value":"1537-1891","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mediterranean G6PD variant rats are protected from Angiotensin II-induced hypertension and kidney damage, but not from inflammation and arterial stiffness","name":"articletitle","label":"Article Title"},{"value":"Vascular Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vph.2022.107002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"107002"}}