{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:53:35Z","timestamp":1777618415429,"version":"3.51.4"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T00:00:00Z","timestamp":1679356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005848","name":"Henry Luce Foundation","doi-asserted-by":"publisher","award":["201602877"],"award-info":[{"award-number":["201602877"]}],"id":[{"id":"10.13039\/100005848","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005848","name":"Henry Luce Foundation","doi-asserted-by":"publisher","award":["20180244"],"award-info":[{"award-number":["20180244"]}],"id":[{"id":"10.13039\/100005848","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005848","name":"Henry Luce Foundation","doi-asserted-by":"publisher","award":["20180247"],"award-info":[{"award-number":["20180247"]}],"id":[{"id":"10.13039\/100005848","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005848","name":"Henry Luce Foundation","doi-asserted-by":"publisher","award":["20200520"],"award-info":[{"award-number":["20200520"]}],"id":[{"id":"10.13039\/100005848","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005848","name":"Henry Luce Foundation","doi-asserted-by":"publisher","award":["20200621"],"award-info":[{"award-number":["20200621"]}],"id":[{"id":"10.13039\/100005848","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005848","name":"Henry Luce Foundation","doi-asserted-by":"publisher","award":["20210466"],"award-info":[{"award-number":["20210466"]}],"id":[{"id":"10.13039\/100005848","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010665","name":"H2020 Marie Sk\u0142odowska-Curie Actions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019771","name":"European Union's Research and Innovation","doi-asserted-by":"publisher","award":["722609"],"award-info":[{"award-number":["722609"]}],"id":[{"id":"10.13039\/100019771","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002996","name":"Hartstichting","doi-asserted-by":"publisher","award":["2019T067"],"award-info":[{"award-number":["2019T067"]}],"id":[{"id":"10.13039\/501100002996","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003748","name":"Svenska S\u00e4llskapet f\u00f6r Medicinsk Forskning","doi-asserted-by":"publisher","award":["P13-0171"],"award-info":[{"award-number":["P13-0171"]}],"id":[{"id":"10.13039\/501100003748","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vascular Pharmacology"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.vph.2023.107167","type":"journal-article","created":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T14:52:25Z","timestamp":1679410345000},"page":"107167","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Mast cells participate in smooth muscle cell reprogramming and atherosclerotic plaque calcification"],"prefix":"10.1016","volume":"150","author":[{"given":"Nikolaos T.","family":"Skenteris","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esmeralda","family":"Hemme","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucie","family":"Delfos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glykeria","family":"Karadimou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Karl\u00f6f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariette","family":"Lengquist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malin","family":"Kronqvist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Maegdefessel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leon J.","family":"Schurgers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hildur","family":"Arnardottir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik A.L.","family":"Biessen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilze","family":"Bot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ljubica","family":"Matic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.vph.2023.107167_bb0005","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1016\/j.jacc.2019.07.061","article-title":"From focal lipid storage to systemic inflammation: JACC review topic of the week","volume":"74","author":"Libby","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"issue":"6","key":"10.1016\/j.vph.2023.107167_bb0010","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nrneph.2017.51","article-title":"The immunology of atherosclerosis","volume":"13","author":"Gistera","year":"2017","journal-title":"Nat. Rev. Nephrol."},{"issue":"7","key":"10.1016\/j.vph.2023.107167_bb0015","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1161\/ATVBAHA.108.179739","article-title":"Concept of vulnerable\/unstable plaque","volume":"30","author":"Finn","year":"2010","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"6","key":"10.1016\/j.vph.2023.107167_bb0020","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1253\/circj.CJ-11-0395","article-title":"Cardiovascular calcification: an inflammatory disease","volume":"75","author":"New","year":"2011","journal-title":"Circulat. J."},{"issue":"13","key":"10.1016\/j.vph.2023.107167_bb0025","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.1093\/cvr\/cvab301","article-title":"Two-faced Janus: the dual role of macrophages in atherosclerotic calcification","volume":"118","author":"Waring","year":"2022","journal-title":"Cardiovasc. Res."},{"issue":"3","key":"10.1016\/j.vph.2023.107167_bb0030","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/joim.12448","article-title":"Gene expression signatures, pathways and networks in carotid atherosclerosis","volume":"279","author":"Perisic","year":"2016","journal-title":"J. Intern. Med."},{"issue":"4","key":"10.1016\/j.vph.2023.107167_bb0035","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.jvs.2009.08.072","article-title":"Systematic review on the association between calcification in carotid plaques and clinical ischemic symptoms","volume":"51","author":"Kwee","year":"2010","journal-title":"J. Vasc. Surg."},{"issue":"9","key":"10.1016\/j.vph.2023.107167_bb0040","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.3174\/ajnr.A7223","article-title":"Roadmap consensus on carotid artery plaque imaging and impact on therapy strategies and guidelines: an international multispecialty, expert review and position statement","volume":"42","author":"Saba","year":"2021","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.vph.2023.107167_bb0045","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.atherosclerosis.2019.05.005","article-title":"Correlation of computed tomography with carotid plaque transcriptomes associates calcification with lesion-stabilization","volume":"288","author":"Karlof","year":"2019","journal-title":"Atherosclerosis"},{"issue":"18","key":"10.1016\/j.vph.2023.107167_bb0050","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1016\/j.jacc.2012.03.012","article-title":"Spotty calcification as a marker of accelerated progression of coronary atherosclerosis: insights from serial intravascular ultrasound","volume":"59","author":"Kataoka","year":"2012","journal-title":"J. Am. Coll. Cardiol."},{"issue":"1","key":"10.1016\/j.vph.2023.107167_bb0055","article-title":"Computed tomographic coronary angiography-derived plaque characteristics predict major adverse cardiovascular events: a systematic review and Meta-analysis","volume":"11","author":"Nerlekar","year":"2018","journal-title":"Circulation. Cardiovasc. Imag."},{"issue":"24","key":"10.1016\/j.vph.2023.107167_bb0060","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1161\/CIRCULATIONAHA.107.732867","article-title":"Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo","volume":"116","author":"Aikawa","year":"2007","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.vph.2023.107167_bb0065","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.ejvs.2021.07.011","article-title":"Carotid plaque phenotyping by correlating plaque morphology from computed tomography angiography with transcriptional profiling","volume":"62","author":"Karlof","year":"2021","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"issue":"6","key":"10.1016\/j.vph.2023.107167_bb0070","doi-asserted-by":"crossref","DOI":"10.3390\/cells10061276","article-title":"Proteoglycan 4 modulates osteogenic smooth muscle cell differentiation during vascular remodeling and intimal calcification","volume":"10","author":"Seime","year":"2021","journal-title":"Cells"},{"issue":"2","key":"10.1016\/j.vph.2023.107167_bb0075","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.682","article-title":"Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification","volume":"12","author":"Skenteris","year":"2022","journal-title":"Clin Transl Med"},{"issue":"5","key":"10.1016\/j.vph.2023.107167_bb0080","first-page":"820","article-title":"Mast cells in atherosclerosis","volume":"106","author":"Bot","year":"2011","journal-title":"Thromb. Haemost."},{"issue":"18","key":"10.1016\/j.vph.2023.107167_bb0085","doi-asserted-by":"crossref","first-page":"4479","DOI":"10.3390\/ijms20184479","article-title":"Mast cells as potential accelerators of human atherosclerosis\u2014from early to late lesions","volume":"20","author":"Kovanen","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.vph.2023.107167_bb0090","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1161\/01.CIR.90.4.1669","article-title":"Accumulation of activated mast cells in the shoulder region of human coronary atheroma, the predilection site of atheromatous rupture","volume":"90","author":"Kaartinen","year":"1994","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.vph.2023.107167_bb0095","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1161\/01.CIR.92.5.1084","article-title":"Infiltrates of activated mast cells at the site of coronary atheromatous erosion or rupture in myocardial infarction","volume":"92","author":"Kovanen","year":"1995","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.vph.2023.107167_bb0100","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1161\/01.CIR.99.3.361","article-title":"Association between myocardial infarction and the mast cells in the adventitia of the infarct-related coronary artery","volume":"99","author":"Laine","year":"1999","journal-title":"Circulation"},{"issue":"1\u20132","key":"10.1016\/j.vph.2023.107167_bb0105","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0021-9150(95)05794-3","article-title":"Mast cells accompany microvessels in human coronary atheromas: implications for intimal neovascularization and hemorrhage","volume":"123","author":"Kaartinen","year":"1996","journal-title":"Atherosclerosis"},{"issue":"10","key":"10.1016\/j.vph.2023.107167_bb0110","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1161\/01.ATV.0000140820.51174.8d","article-title":"Mast cells in neovascularized human coronary plaques store and secrete basic fibroblast growth factor, a potent angiogenic mediator","volume":"24","author":"Lappalainen","year":"2004","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"48","key":"10.1016\/j.vph.2023.107167_bb0115","doi-asserted-by":"crossref","first-page":"3699","DOI":"10.1093\/eurheartj\/eht186","article-title":"Mast cells in human carotid atherosclerotic plaques are associated with intraplaque microvessel density and the occurrence of future cardiovascular events","volume":"34","author":"Willems","year":"2013","journal-title":"Eur. Heart J."},{"issue":"19","key":"10.1016\/j.vph.2023.107167_bb0120","doi-asserted-by":"crossref","first-page":"2516","DOI":"10.1161\/CIRCULATIONAHA.106.660472","article-title":"Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E-deficient mice","volume":"115","author":"Bot","year":"2007","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.vph.2023.107167_bb0125","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.atherosclerosis.2009.04.014","article-title":"Chymase activity is closely related with plaque vulnerability in a hamster model of atherosclerosis","volume":"207","author":"Guo","year":"2009","journal-title":"Atherosclerosis"},{"issue":"1","key":"10.1016\/j.vph.2023.107167_bb0130","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/(SICI)1096-9896(199705)182:1<115::AID-PATH806>3.0.CO;2-9","article-title":"Mast cell distribution, activation, and phenotype in atherosclerotic lesions of human carotid arteries","volume":"182","author":"Jeziorska","year":"1997","journal-title":"J. Pathol."},{"issue":"2","key":"10.1016\/j.vph.2023.107167_bb0135","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1053\/ejvs.2002.1946","article-title":"Overview of the principal results and secondary analyses from the European and north American randomised trials of endarterectomy for symptomatic carotid stenosis","volume":"26","author":"Naylor","year":"2003","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"issue":"9746","key":"10.1016\/j.vph.2023.107167_bb0140","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1016\/S0140-6736(10)61197-X","article-title":"10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial","volume":"376","author":"Halliday","year":"2010","journal-title":"Lancet"},{"issue":"9","key":"10.1016\/j.vph.2023.107167_bb0145","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1161\/ATVBAHA.116.307893","article-title":"Phenotypic modulation of smooth muscle cells in atherosclerosis is associated with downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM","volume":"36","author":"Matic","year":"2016","journal-title":"Arterioscl. Thromb. Vasc. Biol."},{"issue":"10","key":"10.1016\/j.vph.2023.107167_bb0150","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1161\/ATVBAHA.113.301743","article-title":"Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis","volume":"33","author":"Perisic","year":"2013","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"2","key":"10.1016\/j.vph.2023.107167_bb0155","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1148\/radiol.2017170127","article-title":"Atherosclerotic plaque tissue: noninvasive quantitative assessment of characteristics with software-aided measurements from conventional CT angiography","volume":"286","author":"Sheahan","year":"2017","journal-title":"Radiology"},{"issue":"3","key":"10.1016\/j.vph.2023.107167_bb0160","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.jvs.2018.11.050","article-title":"Quantitative assessment of carotid plaque morphology (geometry and tissue composition) using computed tomography angiography","volume":"70","author":"Chrencik","year":"2019","journal-title":"J. Vasc. Surg."},{"issue":"4","key":"10.1016\/j.vph.2023.107167_bb0165","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.jvs.2021.10.056","article-title":"Computed tomography angiographic biomarkers help identify vulnerable carotid artery plaque","volume":"75","author":"Lal","year":"2022","journal-title":"J. Vasc. Surg."},{"issue":"5","key":"10.1016\/j.vph.2023.107167_bb0170","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1161\/ATVBAHA.121.315969","article-title":"Virtual Transcriptomics","volume":"41","author":"Buckler","year":"2021","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"4","key":"10.1016\/j.vph.2023.107167_bb0175","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.jacbts.2018.04.001","article-title":"Novel multiomics profiling of human carotid atherosclerotic plaques and plasma reveals biliverdin reductase b as a marker of intraplaque hemorrhage","volume":"3","author":"Matic","year":"2018","journal-title":"JACC Basic Transl Sci"},{"issue":"5","key":"10.1016\/j.vph.2023.107167_bb0180","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/nmeth.3337","article-title":"Robust enumeration of cell subsets from tissue expression profiles","volume":"12","author":"Newman","year":"2015","journal-title":"Nat. Methods"},{"issue":"7","key":"10.1016\/j.vph.2023.107167_bb0185","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1038\/ni.3445","article-title":"Expression profiling of constitutive mast cells reveals a unique identity within the immune system","volume":"17","author":"Dwyer","year":"2016","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.vph.2023.107167_bb0190","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s40413-016-0094-3","article-title":"Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases","volume":"9","author":"Metcalfe","year":"2016","journal-title":"World Allergy Organ J"},{"key":"10.1016\/j.vph.2023.107167_bb0195","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.ijcard.2018.02.111","article-title":"Statin use is associated with carotid plaque composition: the Rotterdam study","volume":"260","author":"Mujaj","year":"2018","journal-title":"Int. J. Cardiol."},{"issue":"6","key":"10.1016\/j.vph.2023.107167_bb0200","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1161\/01.ATV.14.6.966","article-title":"Mast cells of two types differing in neutral protease composition in the human aortic intima. Demonstration of tryptase- and tryptase\/chymase-containing mast cells in normal intimas, fatty streaks, and the shoulder region of atheromas","volume":"14","author":"Kaartinen","year":"1994","journal-title":"Arterioscler. Thromb."},{"issue":"11","key":"10.1016\/j.vph.2023.107167_bb0205","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1161\/CIRCRESAHA.120.316770","article-title":"Microanatomy of the human atherosclerotic plaque by single-cell transcriptomics","volume":"127","author":"Depuydt","year":"2020","journal-title":"Circ. Res."},{"issue":"4","key":"10.1016\/j.vph.2023.107167_bb0210","doi-asserted-by":"crossref","DOI":"10.3390\/cells8040334","article-title":"Flow cytometry-based characterization of mast cells in human atherosclerosis","volume":"8","author":"Kritikou","year":"2019","journal-title":"Cells"},{"issue":"6","key":"10.1016\/j.vph.2023.107167_bb0215","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.4049\/jimmunol.1202323","article-title":"The tetraspanin CD63 is required for efficient IgE-mediated mast cell degranulation and anaphylaxis","volume":"191","author":"Kraft","year":"2013","journal-title":"J. Immunol."},{"issue":"4","key":"10.1016\/j.vph.2023.107167_bb0220","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1093\/cvr\/cvy010","article-title":"Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness","volume":"114","author":"Durham","year":"2018","journal-title":"Cardiovasc. Res."},{"issue":"1","key":"10.1016\/j.vph.2023.107167_bb0225","doi-asserted-by":"crossref","first-page":"1697583","DOI":"10.1080\/20013078.2019.1697583","article-title":"Characterization of protein, long noncoding RNA and microRNA signatures in extracellular vesicles derived from resting and degranulated mast cells","volume":"9","author":"Liang","year":"2020","journal-title":"J. Extracellular Ves."},{"issue":"12","key":"10.1016\/j.vph.2023.107167_bb0230","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1161\/01.ATV.0000147029.63303.28","article-title":"Decorin promotes aortic smooth muscle cell calcification and colocalizes to calcified regions in human atherosclerotic lesions","volume":"24","author":"Fischer","year":"2004","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.vph.2023.107167_bb0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.bone.2020.115542","article-title":"The role of bone morphogenetic protein signaling in vascular calcification","volume":"141","author":"Yang","year":"2020","journal-title":"Bone"},{"issue":"7","key":"10.1016\/j.vph.2023.107167_bb0240","doi-asserted-by":"crossref","first-page":"5001","DOI":"10.4049\/jimmunol.181.7.5001","article-title":"Mast cells promote airway smooth muscle cell differentiation via autocrine up-regulation of TGF-beta 1","volume":"181","author":"Woodman","year":"2008","journal-title":"J. Immunol."},{"issue":"10","key":"10.1016\/j.vph.2023.107167_bb0245","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1007\/s11255-022-03195-4","article-title":"Both high glucose and phosphate overload promote senescence-associated calcification of vascular muscle cells","volume":"54","author":"Zhang","year":"2022","journal-title":"Int. Urol. Nephrol."},{"issue":"1","key":"10.1016\/j.vph.2023.107167_bb0250","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1161\/ATVBAHA.120.313791","article-title":"Transcriptional programming in arteriosclerotic disease","volume":"41","author":"Chen","year":"2021","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"12","key":"10.1016\/j.vph.2023.107167_bb0255","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1161\/hh2401.101070","article-title":"Smooth muscle cell phenotypic transition associated with calcification","volume":"89","author":"Steitz","year":"2001","journal-title":"Circ. Res."},{"issue":"7","key":"10.1016\/j.vph.2023.107167_bb0260","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1002\/stem.3358","article-title":"A synthetic mRNA cell reprogramming method using CYCLIN D1 promotes DNA repair, generating improved genetically stable human induced pluripotent stem cells","volume":"39","author":"Alvarez-Palomo","year":"2021","journal-title":"Stem Cells"},{"issue":"4","key":"10.1016\/j.vph.2023.107167_bb0265","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.carpath.2009.09.007","article-title":"Common pathogenic features of atherosclerosis and calcific aortic stenosis: role of transforming growth factor-\u03b2","volume":"19","author":"Xu","year":"2010","journal-title":"Cardiovasc. Pathol."},{"issue":"15","key":"10.1016\/j.vph.2023.107167_bb0270","doi-asserted-by":"crossref","first-page":"4353","DOI":"10.7150\/ijbs.66537","article-title":"IL-1\u03b2 in atherosclerotic vascular calcification: from bench to bedside","volume":"17","author":"Shen","year":"2021","journal-title":"Int. J. Biol. Sci."},{"issue":"12","key":"10.1016\/j.vph.2023.107167_bb0275","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1161\/CIRCRESAHA.117.312509","article-title":"Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of aortic macrophages in murine atherosclerosis","volume":"122","author":"Cochain","year":"2018","journal-title":"Circ. Res."},{"issue":"1","key":"10.1016\/j.vph.2023.107167_bb0280","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/(SICI)1096-9896(199805)185:1<10::AID-PATH71>3.0.CO;2-0","article-title":"Calcification in atherosclerotic plaque of human carotid arteries: associations with mast cells and macrophages","volume":"185","author":"Jeziorska","year":"1998","journal-title":"J. Pathol."},{"issue":"3","key":"10.1016\/j.vph.2023.107167_bb0285","doi-asserted-by":"crossref","DOI":"10.3390\/cells9030701","article-title":"Local mast cell activation promotes neovascularization","volume":"9","author":"Bot","year":"2020","journal-title":"Cells"},{"issue":"11","key":"10.1016\/j.vph.2023.107167_bb0290","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1161\/01.CIR.103.11.1522","article-title":"Bone formation and inflammation in cardiac valves","volume":"103","author":"Mohler","year":"2001","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.vph.2023.107167_bb0295","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s10753-012-9565-z","article-title":"Mast cells in human stenotic aortic valves are associated with the severity of stenosis","volume":"36","author":"Wypasek","year":"2013","journal-title":"Inflammation"},{"issue":"4","key":"10.1016\/j.vph.2023.107167_bb0300","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.prp.2012.02.009","article-title":"Calcific aortic valve stenosis: Immunohistochemical analysis of inflammatory infiltrate","volume":"208","author":"\u0160teiner","year":"2012","journal-title":"Pathol. Res. Pract."},{"issue":"1","key":"10.1016\/j.vph.2023.107167_bb0305","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.prp.2017.07.016","article-title":"Mast cells in calcific aortic stenosis","volume":"214","author":"\u0160teiner","year":"2018","journal-title":"Pathol. Res. Pract."},{"issue":"4","key":"10.1016\/j.vph.2023.107167_bb0310","article-title":"Original articleAssociation of mast cells with calcification in the human pineal gland","volume":"48","author":"Ma\u015bli\u0144ska","year":"2010","journal-title":"Folia Neuropathol."},{"issue":"3 Suppl","key":"10.1016\/j.vph.2023.107167_bb0315","first-page":"981","article-title":"Macrophages and mast cells are involved in carotid plaque instability","volume":"52","author":"Marzullo","year":"2011","journal-title":"Romanian J. Morphol. Embryol."},{"issue":"5","key":"10.1016\/j.vph.2023.107167_bb0320","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1159\/000084497","article-title":"Carotid plaque mast cells associate with Atherogenic serum lipids, high grade carotid stenosis and symptomatic carotid artery disease","volume":"19","author":"Lehtonen-Smeds","year":"2005","journal-title":"Cerebrovasc. Dis."},{"key":"10.1016\/j.vph.2023.107167_bb0325","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2021.696244","article-title":"Warfarin treatment is associated to increased internal carotid artery calcification","volume":"12","author":"Nuotio","year":"2021","journal-title":"Front. Neurol."},{"issue":"2","key":"10.1016\/j.vph.2023.107167_bb0330","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0088984","article-title":"Circulating immunoglobulins are not associated with intraplaque mast cell number and other vulnerable plaque characteristics in patients with carotid artery stenosis","volume":"9","author":"Willems","year":"2014","journal-title":"PLoS One"},{"issue":"13","key":"10.1016\/j.vph.2023.107167_bb0335","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1001\/archinte.158.13.1434","article-title":"Prediction of myocardial infarction in dyslipidemic men by elevated levels of immunoglobulin classes A E, and G, but not M","volume":"158","author":"Kovanen","year":"1998","journal-title":"Arch. Intern. Med."},{"issue":"1","key":"10.1016\/j.vph.2023.107167_bb0340","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1161\/CIRCRESAHA.116.309606","article-title":"Increased plasma IgE accelerate atherosclerosis in secreted IgM deficiency","volume":"120","author":"Tsiantoulas","year":"2017","journal-title":"Circ. Res."},{"key":"10.1016\/j.vph.2023.107167_bb0345","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3389\/fimmu.2020.00163","article-title":"The role of mast cells in bone metabolism and bone disorders","volume":"11","author":"Ragipoglu","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.vph.2023.107167_bb0350","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.599415","article-title":"Role of vascular smooth muscle cell plasticity and interactions in Vessel Wall inflammation","volume":"11","author":"Sorokin","year":"2020","journal-title":"Front. Immunol."},{"issue":"11","key":"10.1016\/j.vph.2023.107167_bb0355","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1093\/cvr\/cvab046","article-title":"Vascular smooth muscle cells in atherosclerosis: time for a re-assessment","volume":"117","author":"Grootaert","year":"2021","journal-title":"Cardiovasc. Res."},{"issue":"1\u20133","key":"10.1016\/j.vph.2023.107167_bb0360","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1159\/000237574","article-title":"GM-CSF downregulates expression of tryptase, fc epsilon RI and histamine in HMC-1 mast cells","volume":"113","author":"Welker","year":"1997","journal-title":"Int. Arch. Allergy Immunol."},{"issue":"4","key":"10.1016\/j.vph.2023.107167_bb0365","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1046\/j.1365-2133.2001.04435.x","article-title":"Effect of granulocyte macrophage colony-stimulating factor in a patient with benign systemic mastocytosis","volume":"145","author":"Zuberbier","year":"2001","journal-title":"Br. J. Dermatol."},{"issue":"3","key":"10.1016\/j.vph.2023.107167_bb0370","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1016\/j.ijcard.2013.01.211","article-title":"Nalp3 inflammasome is activated and required for vascular smooth muscle cell calcification","volume":"168","author":"Wen","year":"2013","journal-title":"Int. J. Cardiol."}],"container-title":["Vascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189123000277?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189123000277?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T01:22:14Z","timestamp":1761528134000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1537189123000277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":74,"alternative-id":["S1537189123000277"],"URL":"https:\/\/doi.org\/10.1016\/j.vph.2023.107167","relation":{},"ISSN":["1537-1891"],"issn-type":[{"value":"1537-1891","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mast cells participate in smooth muscle cell reprogramming and atherosclerotic plaque calcification","name":"articletitle","label":"Article Title"},{"value":"Vascular Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vph.2023.107167","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"107167"}}