{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T23:42:11Z","timestamp":1790379731888,"version":"4.1.0"},"reference-count":15,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005230","name":"Natural Science Foundation of Chongqing Municipality","doi-asserted-by":"publisher","award":["CSTB2022NSCQ-MSX1112"],"award-info":[{"award-number":["CSTB2022NSCQ-MSX1112"]}],"id":[{"id":"10.13039\/501100005230","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012232","name":"National Key Clinical Specialty Discipline Construction Program of China","doi-asserted-by":"publisher","award":["2024-363"],"award-info":[{"award-number":["2024-363"]}],"id":[{"id":"10.13039\/501100012232","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010905","name":"Major Research Plan","doi-asserted-by":"publisher","award":["82570558"],"award-info":[{"award-number":["82570558"]}],"id":[{"id":"10.13039\/501100010905","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010905","name":"Major Research Plan","doi-asserted-by":"publisher","award":["82270908"],"award-info":[{"award-number":["82270908"]}],"id":[{"id":"10.13039\/501100010905","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vascular Pharmacology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.vph.2026.107611","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:37:49Z","timestamp":1777588669000},"page":"107611","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Single-cell lineage tracing unveils sex differences in VSMCs derived from the cardiac neural crest and second heart field"],"prefix":"10.1016","volume":"163","author":[{"given":"Yanzhi","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songmao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kailong","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing Rex","family":"Lyu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"14","key":"10.1016\/j.vph.2026.107611_bb0005","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1016\/j.jacc.2020.07.061","article-title":"Type a aortic dissection-experience over 5 decades: JACC historical breakthroughs in perspective","volume":"76","author":"Zhu","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"issue":"9","key":"10.1016\/j.vph.2026.107611_bb0010","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.jacc.2023.05.067","article-title":"Sex differences in thoracic aortic disease and dissection: JACC review topic of the week","volume":"82","author":"Crousillat","year":"2023","journal-title":"J. Am. Coll. Cardiol."},{"issue":"25","key":"10.1016\/j.vph.2026.107611_bb0015","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1161\/CIRCULATIONAHA.122.061065","article-title":"Clinical characteristics, incidences, and mortality rates for type A and B aortic dissections: a nationwide Danish population-based cohort study from 1996 to 2016","volume":"146","author":"Obel","year":"2022","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.vph.2026.107611_bb0020","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1093\/cvr\/cvt040","article-title":"Biomechanical factors in the biology of aortic wall and aortic valve diseases","volume":"99","author":"B\u00e4ck","year":"2013","journal-title":"Cardiovasc. Res."},{"issue":"4","key":"10.1016\/j.vph.2026.107611_bb0025","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1093\/cvr\/cvy009","article-title":"Smooth muscle cell and arterial aging: basic and clinical aspects","volume":"114","author":"Lacolley","year":"2018","journal-title":"Cardiovasc. Res."},{"issue":"1","key":"10.1016\/j.vph.2026.107611_bb0030","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1161\/ATVBAHA.116.303229","article-title":"Altered smooth muscle cell force generation as a driver of thoracic aortic aneurysms and dissections","volume":"37","author":"Milewicz","year":"2017","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"5","key":"10.1016\/j.vph.2026.107611_bb0035","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1161\/CIRCRESAHA.120.318049","article-title":"Generation of vascular smooth muscle cells from induced pluripotent stem cells: methods, applications, and considerations","volume":"128","author":"Shen","year":"2021","journal-title":"Circ. Res."},{"issue":"6","key":"10.1016\/j.vph.2026.107611_bb0040","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1161\/ATVBAHA.107.141069","article-title":"Developmental basis of vascular smooth muscle diversity","volume":"27","author":"Majesky","year":"2007","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"17","key":"10.1016\/j.vph.2026.107611_bb0045","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1161\/CIRCULATIONAHA.124.070782","article-title":"Exploring origin-dependent susceptibility of smooth muscle cells to aortic diseases through intersectional genetics","volume":"151","author":"Han","year":"2025","journal-title":"Circulation"},{"issue":"13","key":"10.1016\/j.vph.2026.107611_bb0050","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1161\/CIRCULATIONAHA.121.058173","article-title":"Second heart field-derived cells contribute to angiotensin II-mediated ascending aortopathies","volume":"145","author":"Sawada","year":"2022","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.vph.2026.107611_bb0055","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1161\/ATVBAHA.124.321706","article-title":"Heterogeneous cardiac-derived and neural crest-derived aortic smooth muscle cells exhibit similar transcriptional changes after TGF\u03b2 signaling disruption","volume":"45","author":"Ren","year":"2025","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"2","key":"10.1016\/j.vph.2026.107611_bb0060","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1161\/ATVBAHA.124.321482","article-title":"Single-cell transcriptomics identifies selective lineage-specific regulation of genes in aortic smooth muscle cells in mice","volume":"45","author":"Shukla","year":"2025","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"11","key":"10.1016\/j.vph.2026.107611_bb0065","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1161\/ATVBAHA.122.317953","article-title":"Aortic cellular diversity and quantitative genome-wide association study trait prioritization through single-nuclear RNA sequencing of the aneurysmal human aorta","volume":"42","author":"Chou","year":"2022","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"4","key":"10.1016\/j.vph.2026.107611_bb0070","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1093\/cvr\/cvy006","article-title":"From genetics to response to injury: vascular smooth muscle cells in aneurysms and dissections of the ascending aorta","volume":"114","author":"Michel","year":"2018","journal-title":"Cardiovasc. Res."},{"issue":"1","key":"10.1016\/j.vph.2026.107611_bb0075","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1038\/s41596-024-01045-4","article-title":"CellChat for systematic analysis of cell-cell communication from single-cell transcriptomics","volume":"20","author":"Jin","year":"2025","journal-title":"Nat. Protoc."}],"container-title":["Vascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189126000315?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189126000315?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:35:32Z","timestamp":1786995332000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1537189126000315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":15,"alternative-id":["S1537189126000315"],"URL":"https:\/\/doi.org\/10.1016\/j.vph.2026.107611","relation":{},"ISSN":["1537-1891"],"issn-type":[{"value":"1537-1891","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Single-cell lineage tracing unveils sex differences in VSMCs derived from the cardiac neural crest and second heart field","name":"articletitle","label":"Article Title"},{"value":"Vascular Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vph.2026.107611","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107611"}}