{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T11:49:08Z","timestamp":1793620148438,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82300554"],"award-info":[{"award-number":["82300554"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LQ24H020003"],"award-info":[{"award-number":["LQ24H020003"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LQ21H07001"],"award-info":[{"award-number":["LQ21H07001"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LY23H020004"],"award-info":[{"award-number":["LY23H020004"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vascular Pharmacology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.vph.2026.107687","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T23:38:12Z","timestamp":1786405092000},"page":"107687","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["circFBXO7 promotes ferroptosis in vascular endothelial cells exposed to high glucose through enhancing proteasomal degradation of TFCP2"],"prefix":"10.1016","volume":"164","author":[{"given":"Chenyang","family":"Qiu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianchi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengyuan","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoran","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenpeng","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawei","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanbo","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziheng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.vph.2026.107687_bb0005","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/s42255-024-01190-w","article-title":"Diabetes in China: epidemiology, pathophysiology and multi-omics","volume":"7","author":"Jia","year":"2025","journal-title":"Nat. Metab."},{"issue":"15","key":"10.1016\/j.vph.2026.107687_bb0010","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1056\/NEJMp078030","article-title":"Diabetes treatment--bridging the divide","volume":"356","author":"Rother","year":"2007","journal-title":"N. Engl. J. Med."},{"issue":"6","key":"10.1016\/j.vph.2026.107687_bb0015","doi-asserted-by":"crossref","first-page":"491","DOI":"10.2217\/fca-2018-0045","article-title":"Type-2 diabetes mellitus and cardiovascular disease","volume":"14","author":"Henning","year":"2018","journal-title":"Futur. Cardiol."},{"issue":"5","key":"10.1016\/j.vph.2026.107687_bb0020","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/1753-0407.12521","article-title":"Macro- and microvascular endothelial dysfunction in diabetes","volume":"9","author":"Shi","year":"2017","journal-title":"J. Diabetes"},{"issue":"7","key":"10.1016\/j.vph.2026.107687_bb0025","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/S0735-1097(03)00994-X","article-title":"The clinical implications of endothelial dysfunction","volume":"42","author":"Widlansky","year":"2003","journal-title":"J. Am. Coll. Cardiol."},{"issue":"11","key":"10.1016\/j.vph.2026.107687_bb0030","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1007\/s13238-021-00841-y","article-title":"Ferroptosis, radiotherapy, and combination therapeutic strategies","volume":"12","author":"Lei","year":"2021","journal-title":"Protein Cell"},{"issue":"2","key":"10.1016\/j.vph.2026.107687_bb0035","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/s41422-020-00441-1","article-title":"Ferroptosis: molecular mechanisms and health implications","volume":"31","author":"Tang","year":"2021","journal-title":"Cell Res."},{"issue":"4","key":"10.1016\/j.vph.2026.107687_bb0040","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41580-020-00324-8","article-title":"Ferroptosis: mechanisms, biology and role in disease","volume":"22","author":"Jiang","year":"2021","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"2","key":"10.1016\/j.vph.2026.107687_bb0045","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.cell.2017.09.021","article-title":"Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease","volume":"171","author":"Stockwell","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.vph.2026.107687_bb0050","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ceb.2017.11.001","article-title":"To eat or not to eat-the metabolic flavor of ferroptosis","volume":"51","author":"Gao","year":"2018","journal-title":"Curr. Opin. Cell Biol."},{"issue":"5","key":"10.1016\/j.vph.2026.107687_bb0055","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.vph.2026.107687_bb0060","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.molcel.2018.10.042","article-title":"Role of mitochondria in ferroptosis","volume":"73","author":"Gao","year":"2019","journal-title":"Mol. Cell"},{"key":"10.1016\/j.vph.2026.107687_bb0065","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2018.01310","article-title":"RBPs play important roles in vascular endothelial dysfunction under diabetic conditions","volume":"9","author":"Yang","year":"2018","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.vph.2026.107687_bb0070","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/s41392-021-00569-5","article-title":"Targeting circular RNAs as a therapeutic approach: current strategies and challenges","volume":"6","author":"He","year":"2021","journal-title":"Signal Transduct. Target. Ther."},{"issue":"1","key":"10.1016\/j.vph.2026.107687_bb0075","doi-asserted-by":"crossref","DOI":"10.1007\/s10142-025-01575-4","article-title":"Emerging role and clinical applications of circular RNAs in human diseases","volume":"25","author":"Sur","year":"2025","journal-title":"Funct. Integr. Genomics"},{"issue":"5","key":"10.1016\/j.vph.2026.107687_bb0080","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1038\/s41419-021-03743-3","article-title":"CircRNAs: role in human diseases and potential use as biomarkers","volume":"12","author":"Verduci","year":"2021","journal-title":"Cell Death Dis."},{"issue":"5","key":"10.1016\/j.vph.2026.107687_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2025.167797","article-title":"The IGF2BP2-circ-DAPK1 axis promotes high-glucose-induced ferroptosis of HUVECs by decreasing NQO1 expression","volume":"1871","author":"Qiu","year":"2025","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"issue":"1","key":"10.1016\/j.vph.2026.107687_bb0090","first-page":"359","article-title":"Overexpression of circRNA-001175 promotes proliferation and angiogenesis and inhibits apoptosis of the human umbilical vein endothelial cells (HUVECs) induced by high glucose","volume":"11","author":"Pei","year":"2018","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"1","key":"10.1016\/j.vph.2026.107687_bb0095","doi-asserted-by":"crossref","DOI":"10.1186\/s12943-022-01611-y","article-title":"CircFBXO7\/miR-96-5p\/MTSS1 axis is an important regulator in the Wnt signaling pathway in ovarian cancer","volume":"21","author":"Wu","year":"2022","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.vph.2026.107687_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2022.146972","article-title":"The characteristics of FBXO7 and its role in human diseases","volume":"851","author":"Zhong","year":"2023","journal-title":"Gene"},{"issue":"9","key":"10.1016\/j.vph.2026.107687_bb0105","doi-asserted-by":"crossref","DOI":"10.3390\/biom12091320","article-title":"Role of circRNA in E3 modification under human disease","volume":"12","author":"Chen","year":"2022","journal-title":"Biomolecules"},{"issue":"1","key":"10.1016\/j.vph.2026.107687_bb0110","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1038\/s41392-023-01400-z","article-title":"Diabetic vascular diseases: molecular mechanisms and therapeutic strategies","volume":"8","author":"Li","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"issue":"1","key":"10.1016\/j.vph.2026.107687_bb0115","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/s12933-025-02614-x","article-title":"Ferroptosis: mechanism and role in diabetes-related cardiovascular diseases","volume":"24","author":"Wang","year":"2025","journal-title":"Cardiovasc. Diabetol."},{"issue":"2","key":"10.1016\/j.vph.2026.107687_bb0120","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.ncrna.2024.02.001","article-title":"Expanding roles of circRNAs in cardiovascular diseases","volume":"9","author":"Liu","year":"2024","journal-title":"Non-coding RNA Research."},{"issue":"11","key":"10.1016\/j.vph.2026.107687_bb0125","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1038\/s41417-022-00492-z","article-title":"CircRNA circ_0006156 inhibits the metastasis of prostate cancer by blocking the ubiquitination of S100A9","volume":"29","author":"Zhang","year":"2022","journal-title":"Cancer Gene Ther."},{"issue":"1","key":"10.1016\/j.vph.2026.107687_bb0130","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/s12943-020-01286-3","article-title":"Circular RNA: metabolism, functions and interactions with proteins","volume":"19","author":"Zhou","year":"2020","journal-title":"Mol. Cancer"},{"issue":"3","key":"10.1016\/j.vph.2026.107687_bb0135","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1007\/s10555-024-10175-w","article-title":"TFCP2 as a therapeutic nexus: unveiling molecular signatures in cancer","volume":"43","author":"Kaushik","year":"2024","journal-title":"Cancer Metastasis Rev."},{"key":"10.1016\/j.vph.2026.107687_bb0140","article-title":"Transcriptional repression of ferritin light chain increases ferroptosis sensitivity in lung adenocarcinoma","volume":"9","author":"Wang","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"9","key":"10.1016\/j.vph.2026.107687_bb0145","doi-asserted-by":"crossref","DOI":"10.1038\/s41419-019-1894-5","article-title":"CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer","volume":"10","author":"Liu","year":"2019","journal-title":"Cell Death Dis."}],"container-title":["Vascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189126001072?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1537189126001072?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T03:24:34Z","timestamp":1788578674000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1537189126001072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":29,"alternative-id":["S1537189126001072"],"URL":"https:\/\/doi.org\/10.1016\/j.vph.2026.107687","relation":{},"ISSN":["1537-1891"],"issn-type":[{"value":"1537-1891","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"circFBXO7 promotes ferroptosis in vascular endothelial cells exposed to high glucose through enhancing proteasomal degradation of TFCP2","name":"articletitle","label":"Article Title"},{"value":"Vascular Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vph.2026.107687","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107687"}}