{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T19:28:05Z","timestamp":1766172485287,"version":"3.48.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003624","name":"Ministry of Agriculture, Food and Rural Affairs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003624","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003668","name":"Korea Institute of Planning and Evaluation for Technology in Food Agriculture Forestry and Fisheries","doi-asserted-by":"publisher","award":["RS-2022 IP322103"],"award-info":[{"award-number":["RS-2022 IP322103"]}],"id":[{"id":"10.13039\/501100003668","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","award":["2025-RISE-17-001"],"award-info":[{"award-number":["2025-RISE-17-001"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002449","name":"Jeju National University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002449","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014189","name":"Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014189","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Parasitology: Regional Studies and Reports"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.vprsr.2025.101381","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T10:43:00Z","timestamp":1763635380000},"page":"101381","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Pyrosequencing analysis of cytochrome b (CYTb) gene mutations in Babesia gibsoni: Correlation with drug resistance and treatment efficacy in South Korea"],"prefix":"10.1016","volume":"66","author":[{"given":"Galle Hettiarachchilage Ravindi Ashani","family":"Gunawardhana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doosung","family":"Cheon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woo-Jin","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyohoon","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YoungMin","family":"Yun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.vprsr.2025.101381_bb0005","article-title":"Molecular identification and characterization of piroplasms infecting cattle in Azad Kashmir","volume":"44","author":"Ahmed","year":"2024","journal-title":"Pak. Vet. J."},{"issue":"9","key":"10.1016\/j.vprsr.2025.101381_bb0010","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1292\/jvms.20-0209","article-title":"An alternative combination therapy with metronidazole, clindamycin and doxycycline for Babesia gibsoni (Asian genotype) in dogs in Hong Kong","volume":"82","author":"Almendros","year":"2020","journal-title":"J. Vet. Med. Sci."},{"issue":"4","key":"10.1016\/j.vprsr.2025.101381_bb0015","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.vetpar.2008.09.025","article-title":"Molecular detection of Theileria and Babesia infections in cattle","volume":"158","author":"Altay","year":"2008","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vprsr.2025.101381_bb0020","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2020.620462","article-title":"Porcine babesiosis caused by babesia sp. suis in a pot-bellied pig in South Africa","volume":"7","author":"Avenant","year":"2021","journal-title":"Front. Vet. Sci."},{"issue":"1","key":"10.1016\/j.vprsr.2025.101381_bb0025","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1186\/s13071-024-06371-w","article-title":"Description of Babesia galileei sp. nov. A piroplasmid species causing severe disease in domestic cats","volume":"17","author":"Baneth","year":"2024","journal-title":"Parasit. Vectors"},{"issue":"4","key":"10.1016\/j.vprsr.2025.101381_bb0030","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1111\/j.1939-1676.2004.tb02573.x","article-title":"Efficacy of combined atovaquone and azithromycin for therapy of chronic Babesia gibsoni (Asian genotype) infections in dogs","volume":"18","author":"Birkenheuer","year":"2004","journal-title":"J. Vet. Intern. Med."},{"key":"10.1016\/j.vprsr.2025.101381_bb0035","first-page":"33","article-title":"Babesia gibsoni: an emerging pathogen in dogs","volume":"2","author":"Boozer","year":"2005","journal-title":"Compendium"},{"key":"10.1016\/j.vprsr.2025.101381_bb0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13071-017-2049-0","article-title":"Efficacy, safety and tolerance of imidocarb dipropionate versus atovaquone or buparvaquone plus azithromycin used to treat sick dogs naturally infected with the Babesia microti-like piroplasm","volume":"10","author":"Checa","year":"2017","journal-title":"Parasit. Vectors"},{"issue":"1\u20132","key":"10.1016\/j.vprsr.2025.101381_bb0045","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.vetpar.2003.08.006","article-title":"Molecular characterization of a Babesia gibsoni isolate from a Spanish dog","volume":"117","author":"Criado-Fornelio","year":"2003","journal-title":"Vet. Parasitol."},{"issue":"1","key":"10.1016\/j.vprsr.2025.101381_bb0050","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1196\/annals.1428.036","article-title":"Water buffalos as carriers of Babesia bovis in Argentina","volume":"1149","author":"Ferreri","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"3\u20134","key":"10.1016\/j.vprsr.2025.101381_bb0055","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.mcp.2006.01.002","article-title":"Sentinel-base DNA genotyping using multiple sequencing primers for high-risk human papillomaviruses","volume":"20","author":"Gharizadeh","year":"2006","journal-title":"Mol. Cell. Probes"},{"issue":"11","key":"10.1016\/j.vprsr.2025.101381_bb0060","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1292\/jvms.20-0382","article-title":"Further epidemiological survey for atovaquone resistant related gene of Babesia gibsoni in Japan during 2015\u20132018","volume":"82","author":"Iguchi","year":"2020","journal-title":"J. Vet. Med. Sci."},{"issue":"6","key":"10.1016\/j.vprsr.2025.101381_bb0065","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1128\/JCM.42.6.2465-2469.2004","article-title":"Molecular evidence of infections with Babesia gibsoni parasites in Japan and evaluation of the diagnostic potential of a loop-mediated isothermal amplification method","volume":"42","author":"Ikadai","year":"2004","journal-title":"J. Clin. Microbiol."},{"issue":"Suppl. 1","key":"10.1016\/j.vprsr.2025.101381_bb0070","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1186\/1756-3305-2-S1-S4","article-title":"Canine babesiosis: from molecular taxonomy to control","volume":"2","author":"Irwin","year":"2009","journal-title":"Parasit. Vectors"},{"issue":"2","key":"10.1016\/j.vprsr.2025.101381_bb0075","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1645\/0022-3395(2003)089[0409:TSOCBI]2.0.CO;2","article-title":"Two species of canine Babesia in Australia: detection and characterization by PCR","volume":"89","author":"Jefferies","year":"2003","journal-title":"J. Parasitol."},{"key":"10.1016\/j.vprsr.2025.101381_bb0080","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1007\/s12639-019-01109-3","article-title":"Detection of incidence of Babesia spp. in sheep and goats by parasitological diagnostic techniques","volume":"43","author":"Kage","year":"2019","journal-title":"J. Parasit. Dis."},{"key":"10.1016\/j.vprsr.2025.101381_bb0085","first-page":"119","article-title":"Canine babesiosis: a perspective on clinical complications, biomarkers, and treatment","author":"K\u00f6ster","year":"2015","journal-title":"Vet. Med. Res. Rep."},{"issue":"6","key":"10.1016\/j.vprsr.2025.101381_bb0090","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1089\/vbz.2008.0116","article-title":"Epidemiologic and clinical surveys in dogs infected with Babesia gibsoni in South Korea","volume":"9","author":"Lee","year":"2009","journal-title":"Vector Borne Zoonotic Dis."},{"year":"1988","series-title":"The Protozoan Phylum Apicomplexa","author":"Levine","key":"10.1016\/j.vprsr.2025.101381_bb0095"},{"issue":"3\u20134","key":"10.1016\/j.vprsr.2025.101381_bb0100","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.vetpar.2011.11.073","article-title":"The therapeutic efficacy of two antibabesial strategies against Babesia gibsoni","volume":"186","author":"Lin","year":"2012","journal-title":"Vet. Parasitol."},{"issue":"5","key":"10.1016\/j.vprsr.2025.101381_bb0105","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.ttbdis.2016.02.009","article-title":"A SimpleProbe\u00ae real-time PCR assay for differentiating the cytochrome b M121I mutation in clinical specimens from dogs infected with Babesia gibsoni","volume":"7","author":"Liu","year":"2016","journal-title":"Ticks Tick-Borne Dis."},{"issue":"3","key":"10.1016\/j.vprsr.2025.101381_bb0110","doi-asserted-by":"crossref","first-page":"325","DOI":"10.2460\/javma.2002.220.325","article-title":"Babesia gibsoni infection among dogs in the southeastern United States","volume":"220","author":"Macintire","year":"2002","journal-title":"J. Am. Vet. Med. Assoc."},{"issue":"4","key":"10.1016\/j.vprsr.2025.101381_bb0115","doi-asserted-by":"crossref","first-page":"593","DOI":"10.4269\/ajtmh.2006.74.593","article-title":"Cloning of the Babesia gibsoni cytochrome b gene and isolation of three single nucleotide polymorphisms from parasites present after atovaquone treatment","volume":"74","author":"Matsuu","year":"2006","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"4","key":"10.1016\/j.vprsr.2025.101381_bb0120","first-page":"1315","article-title":"First clinical evidence with one-year monitoring of Babesia gibsoni mono-infection in two dogs from Serbia","volume":"44","author":"Milo\u0161evi\u0107","year":"2024","journal-title":"Pak. Vet. J."},{"issue":"3","key":"10.1016\/j.vprsr.2025.101381_bb0125","first-page":"112","article-title":"New therapeutic protocol for canine babesiosis: a case report","volume":"3","author":"Nandini","year":"2016","journal-title":"J. Dairy Vet. Anim. Res."},{"issue":"1","key":"10.1016\/j.vprsr.2025.101381_bb0130","first-page":"41","article-title":"Detection of Babesia bigemina cases in dogs in rural areas\/T\u00fcrkiye by molecular methods","volume":"30","author":"Ozkan","year":"2024"},{"key":"10.1016\/j.vprsr.2025.101381_bb0135","first-page":"33","article-title":"Animal babesiosis: an emerging zoonosis also in Italy?","volume":"49","author":"Pietrobelli","year":"2007","journal-title":"Parassitologia"},{"key":"10.1016\/j.vprsr.2025.101381_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2022.109823","article-title":"Multiple point mutations in cytochrome b gene of Babesia gibsoni\u2013a possible cause for buparvaquone resistance","volume":"312","author":"Rahman","year":"2022","journal-title":"Vet. Parasitol."},{"issue":"2","key":"10.1016\/j.vprsr.2025.101381_bb0145","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1006\/abio.2000.4808","article-title":"Improved performance of pyrosequencing using single-stranded DNA-binding protein","volume":"286","author":"Ronaghi","year":"2000","journal-title":"Anal. Biochem."},{"issue":"3","key":"10.1016\/j.vprsr.2025.101381_bb0150","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1939-1676.2009.0300.x","article-title":"Possible emergence of drug-resistant variants of Babesia gibsoni in clinical cases treated with atovaquone and azithromycin","volume":"23","author":"Sakuma","year":"2009","journal-title":"J. Vet. Intern. Med."},{"issue":"10","key":"10.1016\/j.vprsr.2025.101381_bb0155","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1292\/jvms.12-0140","article-title":"Molecular epidemiological survey of the Babesia gibsoni cytochrome b gene in western Japan","volume":"74","author":"Sakuma","year":"2012","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.vprsr.2025.101381_bb0160","doi-asserted-by":"crossref","first-page":"19S","DOI":"10.1007\/BF02632910","article-title":"Babesiasis in Nanjing area, China","volume":"29","author":"Shen","year":"1997","journal-title":"Trop. Anim. Health Prod."},{"issue":"1","key":"10.1016\/j.vprsr.2025.101381_bb0165","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.vetpar.2011.04.023","article-title":"Babesiosis in dogs and cats\u2014expanding parasitological and clinical spectra","volume":"181","author":"Solano-Gallego","year":"2011","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vprsr.2025.101381_bb0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13071-016-1596-0","article-title":"A review of canine babesiosis: the European perspective","volume":"9","author":"Solano-Gallego","year":"2016","journal-title":"Parasit. Vectors"},{"issue":"7","key":"10.1016\/j.vprsr.2025.101381_bb0175","doi-asserted-by":"crossref","first-page":"439","DOI":"10.3390\/ani9070439","article-title":"Genetic diversity of canine Babesia species prevalent in pet dogs of Punjab, Pakistan","volume":"9","author":"Tayyub","year":"2019","journal-title":"Animals"},{"key":"10.1016\/j.vprsr.2025.101381_bb0180","series-title":"Parasitic Protozoa","first-page":"1","article-title":"CHAPTER 1 - babesial infections in humans and wildlife","author":"Telford","year":"1993"},{"issue":"6","key":"10.1016\/j.vprsr.2025.101381_bb0185","doi-asserted-by":"crossref","first-page":"730","DOI":"10.3390\/ani12060730","article-title":"Babesia gibsoni infection in dogs\u2014a European perspective","volume":"12","author":"Teodorowski","year":"2022","journal-title":"Animals"},{"issue":"1\u20132","key":"10.1016\/j.vprsr.2025.101381_bb0190","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.vetpar.2006.04.036","article-title":"Babesia gibsoni genotype Asia in dogs from Brazil","volume":"141","author":"Trapp","year":"2006","journal-title":"Vet. Parasitol."},{"issue":"3\u20134","key":"10.1016\/j.vprsr.2025.101381_bb0195","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.vetpar.2009.07.022","article-title":"Clinicopathological findings, molecular detection and characterization of Babesia gibsoni infection in a sick dog from Italy","volume":"165","author":"Trotta","year":"2009","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vprsr.2025.101381_bb0200","article-title":"Babesia gibsoni emerging with high prevalence and co-infections in \u201cfighting dogs\u201d in Hungary","volume":"1","author":"Tuska-Szalay","year":"2021","journal-title":"Curr. Res. Parasitol. Vector Borne Dis."},{"issue":"1\u20132","key":"10.1016\/j.vprsr.2025.101381_bb0205","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.vetpar.2006.01.035","article-title":"Babesia\u2014a historical overview","volume":"138","author":"Uilenberg","year":"2006","journal-title":"Vet. Parasitol."},{"issue":"1\u20132","key":"10.1016\/j.vprsr.2025.101381_bb0210","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.vetpar.2006.01.048","article-title":"Chemotherapy against babesiosis","volume":"138","author":"Vial","year":"2006","journal-title":"Vet. Parasitol."},{"year":"2017","series-title":"Efficacy Study of Clindamycin as Potential Monotherapy Treatment Plan for Clinical Case of Dogs Infected with Babesia Gibsoni","author":"Vishnurahav","key":"10.1016\/j.vprsr.2025.101381_bb0215"},{"key":"10.1016\/j.vprsr.2025.101381_bb0220","series-title":"Veterinary Medicine and Pharmaceuticals","first-page":"109","article-title":"Overview of canine babesiosis","author":"Vishwakarma","year":"2019"}],"container-title":["Veterinary Parasitology: Regional Studies and Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405939025001893?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405939025001893?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T19:24:12Z","timestamp":1766172252000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405939025001893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":44,"alternative-id":["S2405939025001893"],"URL":"https:\/\/doi.org\/10.1016\/j.vprsr.2025.101381","relation":{},"ISSN":["2405-9390"],"issn-type":[{"type":"print","value":"2405-9390"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pyrosequencing analysis of cytochrome b (CYTb) gene mutations in Babesia gibsoni: Correlation with drug resistance and treatment efficacy in South Korea","name":"articletitle","label":"Article Title"},{"value":"Veterinary Parasitology: Regional Studies and Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vprsr.2025.101381","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101381"}}