{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T02:21:57Z","timestamp":1789438917742,"version":"build-2803163510"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51808540"],"award-info":[{"award-number":["51808540"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011395","name":"Major Science and Technology Program for Water Pollution Control and Treatment","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011395","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","award":["2017ZX07102-002"],"award-info":[{"award-number":["2017ZX07102-002"]}],"id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Waste Management"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.wasman.2021.10.010","type":"journal-article","created":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T01:10:21Z","timestamp":1634605821000},"page":"122-131","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"special_numbering":"C","title":["Zero valent iron improved methane production and specifically reduced aminoglycoside and tetracycline resistance genes in anaerobic digestion"],"prefix":"10.1016","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7959-2701","authenticated-orcid":false,"given":"Junya","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiedong","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peihong","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuansong","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wasman.2021.10.010_b0005","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1128\/AEM.67.1.22-32.2001","article-title":"Molecular Ecology of Tetracycline Resistance : Development and Validation of Primers for Detection of Tetracycline Resistance Genes Encoding Ribosomal Protection Proteins","volume":"67","author":"Aminov","year":"2001","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.wasman.2021.10.010_b0010","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.watres.2015.02.043","article-title":"Application of real-time PCR to determination of combined effect of antibiotics on Bacteria, Methanogenic Archaea, Archaea in anaerobic sequencing batch reactors","volume":"76","author":"Aydin","year":"2015","journal-title":"Water Res."},{"key":"10.1016\/j.wasman.2021.10.010_b0015","first-page":"361","article-title":"Gephi: An open source software for exploring and manipulating networks","volume":"2","author":"Bastian","year":"2009","journal-title":"Proc. Third Int. ICWSM Conf."},{"key":"10.1016\/j.wasman.2021.10.010_b0020","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.wasman.2019.05.036","article-title":"Enhanced methanogenic performance and metabolic pathway of high solid anaerobic digestion of chicken manure by Fe2+ and Ni2+ supplementation","volume":"94","author":"Bi","year":"2019","journal-title":"Waste Manag."},{"key":"10.1016\/j.wasman.2021.10.010_b0025","doi-asserted-by":"crossref","first-page":"123816","DOI":"10.1016\/j.jhazmat.2020.123816","article-title":"Profiles of antibiotic resistome and microbial community in groundwater of CKDu prevalence zones in Sri Lanka","volume":"403","author":"Cooray","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.wasman.2021.10.010_b0030","article-title":"Antibiotics on the Farm : Agriculture\u2019s Role in Drug Resistance","volume":"059","author":"Elliott","year":"2015","journal-title":"CGD Policy Paper"},{"issue":"6","key":"10.1016\/j.wasman.2021.10.010_b0035","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.chemosphere.2013.05.082","article-title":"Transcriptional and proteomic stress responses of a soil bacterium bacillus cereus to nanosized zero-valent iron (nZVI) particles","volume":"93","author":"Fajardo","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.wasman.2021.10.010_b0040","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.watres.2016.12.047","article-title":"The role of zero valent iron on the fate of tetracycline resistance genes and class 1 integrons during thermophilic anaerobic co-digestion of waste sludge and kitchen waste","volume":"111","author":"Gao","year":"2017","journal-title":"Water Res."},{"issue":"3-4","key":"10.1016\/j.wasman.2021.10.010_b0045","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1574-6968.1990.tb04928.x","article-title":"Taxonomy and ecology of methanogens","volume":"87","author":"Garcia","year":"1990","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.wasman.2021.10.010_b0050","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.watres.2017.03.048","article-title":"Analysing the mechanisms of sludge digestion enhanced by iron","volume":"117","author":"Hao","year":"2017","journal-title":"Water Res."},{"key":"10.1016\/j.wasman.2021.10.010_b0055","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.envint.2017.07.003","article-title":"Environmental and human health challenges of industrial livestock and poultry farming in China and their mitigation","volume":"107","author":"Hu","year":"2017","journal-title":"Environ. Int."},{"key":"10.1016\/j.wasman.2021.10.010_b0060","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.biortech.2018.08.106","article-title":"Temperature shapes the microbiota in anaerobic digestion and drives efficiency to a maximum at 45 \u00b0C","volume":"269","author":"Hupfauf","year":"2018","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.wasman.2021.10.010_b0065","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1126\/science.347.6223.704","article-title":"China\u2019s lakes of pig manure spawn antibiotic resistance","volume":"347","author":"Larson","year":"2015","journal-title":"Science (80-.)"},{"key":"10.1016\/j.wasman.2021.10.010_b0070","doi-asserted-by":"crossref","first-page":"121393","DOI":"10.1016\/j.biortech.2019.121393","article-title":"Effects of ferric oxide on the microbial community and functioning during anaerobic digestion of swine manure","volume":"287","author":"Lu","year":"2019","journal-title":"Bioresour. Technol."},{"issue":"1","key":"10.1016\/j.wasman.2021.10.010_b0075","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1021\/acs.est.5b03522","article-title":"Metagenomic Assembly Reveals Hosts of Antibiotic Resistance Genes and the Shared Resistome in Pig, Chicken, and Human Feces","volume":"50","author":"Ma","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.wasman.2021.10.010_b0080","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.wasman.2020.08.021","article-title":"Relieving ammonia inhibition by zero-valent iron (ZVI) dosing to enhance methanogenesis in the high solid anaerobic digestion of swine manure","volume":"118","author":"Meng","year":"2020","journal-title":"Waste Manag."},{"key":"10.1016\/j.wasman.2021.10.010_b0085","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.cej.2018.11.135","article-title":"Impact of nano zero valent iron on tetracycline degradation and microbial community succession during anaerobic digestion","volume":"359","author":"Pan","year":"2019","journal-title":"Chem. Eng. J."},{"issue":"7","key":"10.1016\/j.wasman.2021.10.010_b0090","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.1128\/AEM.01285-09","article-title":"Detection and quantification of functional genes of cellulosedegrading, fermentative, and sulfate-reducing bacteria and methanogenic archaea","volume":"76","author":"Pereyra","year":"2010","journal-title":"Appl. Environ. Microbiol."},{"issue":"6435","key":"10.1016\/j.wasman.2021.10.010_b0095","doi-asserted-by":"crossref","first-page":"eaau4679","DOI":"10.1126\/science.aau4679","article-title":"The challenge of antimicrobial resistance: What economics can contribute","volume":"364","author":"Roope","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.wasman.2021.10.010_b0100","doi-asserted-by":"crossref","first-page":"735","DOI":"10.2166\/wst.2008.097","article-title":"Ammonia, a selective agent for methane production by syntrophic acetate oxidation at mesophilic temperature","volume":"57","author":"Schn\u00fcrer","year":"2008","journal-title":"Water Sci. Technol."},{"key":"10.1016\/j.wasman.2021.10.010_b0105","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1099\/ijs.0.64734-0","article-title":"Syntrophomonas zehnderi sp. nov., an anaerobe that degrades long-chain fatty acids in co-culture with Methanobacterium formicicum","volume":"57","author":"Sousa","year":"2007","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"10.1016\/j.wasman.2021.10.010_b0110","doi-asserted-by":"crossref","first-page":"fiy130","DOI":"10.1093\/femsec\/fiy130","article-title":"Primer set 2.0 for highly parallel qPCR array targeting antibiotic resistance genes and mobile genetic elements","volume":"94","author":"Stedtfeld","year":"2018","journal-title":"FEMS Microbiol. Ecol."},{"key":"10.1016\/j.wasman.2021.10.010_b0115","unstructured":"UNEP, 2017. Frontiers 2017: Emerging issues of environmental concern."},{"key":"10.1016\/j.wasman.2021.10.010_b0120","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1128\/AEM.00062-07","article-title":"Na\u00efve Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy","volume":"73","author":"Wang","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.wasman.2021.10.010_b0125","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.cej.2018.06.160","article-title":"Zero valent iron enhances methane production from primary sludge in anaerobic digestion","volume":"351","author":"Wei","year":"2018","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.wasman.2021.10.010_b0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jhazmat.2014.12.029","article-title":"Performance of a zero valent iron-based anaerobic system in swine wastewater treatment","volume":"286","author":"Wu","year":"2015","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.wasman.2021.10.010_b0135","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.wasman.2020.12.003","article-title":"Performance prediction of ZVI-based anaerobic digestion reactor using machine learning algorithms","volume":"121","author":"Xu","year":"2021","journal-title":"Waste Manag."},{"key":"10.1016\/j.wasman.2021.10.010_b0140","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.biortech.2018.09.008","article-title":"Enhanced anaerobic digestion of ammonia-rich swine manure by zero-valent iron: With special focus on the enhancement effect on hydrogenotrophic methanogenesis activity","volume":"270","author":"Yang","year":"2018","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.wasman.2021.10.010_b0145","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.wasman.2020.04.004","article-title":"Exploring the roles of zero-valent iron in two-stage food waste anaerobic digestion","volume":"107","author":"Yuan","year":"2020","journal-title":"Waste Manag."},{"key":"10.1016\/j.wasman.2021.10.010_b0150","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.scitotenv.2018.12.175","article-title":"Which animal type contributes the most to the emission of antibiotic resistance genes in large-scale swine farms in China?","volume":"658","author":"Zhang","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.wasman.2021.10.010_b0155","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.chemosphere.2019.05.036","article-title":"The role of substrate types and substrate microbial community on the fate of antibiotic resistance genes during anaerobic digestion","volume":"229","author":"Zhang","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.wasman.2021.10.010_b0160","doi-asserted-by":"crossref","first-page":"121847","DOI":"10.1016\/j.biortech.2019.121847","article-title":"Effects of magnetite on anaerobic digestion of swine manure: attention to methane production and fate of antibiotic resistance genes","volume":"291","author":"Zhang","year":"2019","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.wasman.2021.10.010_b0165","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.biortech.2015.10.037","article-title":"Optimization and microbial community analysis of anaerobic co-digestion of food waste and sewage sludge based on microwave pretreatment","volume":"200","author":"Zhang","year":"2016","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.wasman.2021.10.010_b0170","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.watres.2016.09.055","article-title":"Sludge Bio-drying: Effective to Reduce both Antibiotic Resistance Genes and Mobile Genetic Elements","volume":"106","author":"Zhang","year":"2016","journal-title":"Water Res."},{"key":"10.1016\/j.wasman.2021.10.010_b0175","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.biortech.2018.03.005","article-title":"Impacts of zero valent iron, natural zeolite and Dnase on the fate of antibiotic resistance genes during thermophilic and mesophilic anaerobic digestion of swine manure","volume":"258","author":"Zhang","year":"2018","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.wasman.2021.10.010_b0180","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.jhazmat.2018.11.106","article-title":"Response and mechanisms of the performance and fate of antibiotic resistance genes to nano-magnetite during anaerobic digestion of swine manure","volume":"366","author":"Zhang","year":"2019","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.wasman.2021.10.010_b0185","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.biortech.2017.08.217","article-title":"Effects of graphene oxide on the performance, microbial community dynamics and antibiotic resistance genes reduction during anaerobic digestion of swine manure","volume":"245","author":"Zhang","year":"2017","journal-title":"Bioresour. Technol."},{"issue":"11","key":"10.1016\/j.wasman.2021.10.010_b0190","doi-asserted-by":"crossref","first-page":"6772","DOI":"10.1021\/acs.est.5b00729","article-title":"Comprehensive evaluation of antibiotics emission and fate in the river basins of China: Source analysis, multimedia modeling, and linkage to bacterial resistance","volume":"49","author":"Zhang","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.wasman.2021.10.010_b0195","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.watres.2018.12.034","article-title":"Deciphering of microbial community and antibiotic resistance genes in activated sludge reactors under high selective pressure of different antibiotics","volume":"151","author":"Zhao","year":"2019","journal-title":"Water Res."},{"key":"10.1016\/j.wasman.2021.10.010_b0200","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.renene.2019.01.055","article-title":"Application of ethanol-type fermentation in establishment of direct interspecies electron transfer: A practical engineering case study","volume":"136","author":"Zhao","year":"2019","journal-title":"Renew. Energy"},{"issue":"9","key":"10.1016\/j.wasman.2021.10.010_b0205","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1073\/pnas.1222743110","article-title":"Diverse and abundant antibiotic resistance genes in Chinese swine farms","volume":"110","author":"Zhu","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4","key":"10.1016\/j.wasman.2021.10.010_b0210","doi-asserted-by":"crossref","DOI":"10.1038\/nmicrobiol.2016.270","article-title":"Continental-scale pollution of estuaries with antibiotic resistance genes","volume":"2","author":"Zhu","year":"2017","journal-title":"Nat. Microbiol."},{"issue":"14","key":"10.1016\/j.wasman.2021.10.010_b0215","doi-asserted-by":"crossref","first-page":"7290","DOI":"10.1021\/acs.est.6b01897","article-title":"Environmental Remediation and Application of Nanoscale Zero-Valent Iron and Its Composites for the Removal of Heavy Metal Ions: A Review","volume":"50","author":"Zou","year":"2016","journal-title":"Environ. Sci. Technol."}],"container-title":["Waste Management"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956053X21005468?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956053X21005468?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T17:51:50Z","timestamp":1760637110000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956053X21005468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":43,"alternative-id":["S0956053X21005468"],"URL":"https:\/\/doi.org\/10.1016\/j.wasman.2021.10.010","relation":{},"ISSN":["0956-053X"],"issn-type":[{"value":"0956-053X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Zero valent iron improved methane production and specifically reduced aminoglycoside and tetracycline resistance genes in anaerobic digestion","name":"articletitle","label":"Article Title"},{"value":"Waste Management","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wasman.2021.10.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}