{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T07:33:16Z","timestamp":1770276796849,"version":"3.49.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Water Research"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.watres.2018.07.032","type":"journal-article","created":{"date-parts":[[2018,7,17]],"date-time":"2018-07-17T10:07:16Z","timestamp":1531822036000},"page":"265-273","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["Fundamental study of the ultrasonic induced degradation of the popular antihistamine, diphenhydramine (DPH)"],"prefix":"10.1016","volume":"144","author":[{"given":"Danni","family":"Cui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander M.","family":"Mebel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis E.","family":"Arroyo-Mora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"De Caprio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"O'Shea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.watres.2018.07.032_bib1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0920-5861(99)00102-9","article-title":"Advanced oxidation processes ( AOP ) for water purification and recovery","volume":"53","author":"Andreozzi","year":"1999","journal-title":"Catal. Today"},{"key":"10.1016\/j.watres.2018.07.032_bib2","series-title":"Elements of Physical Chemistry","author":"Atkins","year":"2013"},{"key":"10.1016\/j.watres.2018.07.032_bib3","doi-asserted-by":"crossref","first-page":"6927","DOI":"10.1021\/jp980930t","article-title":"Chemical bubble dynamics and quantitative sonochemistry","volume":"102","author":"Colussi","year":"1998","journal-title":"J.\u00a0Phys. Chem. A"},{"key":"10.1016\/j.watres.2018.07.032_bib4","series-title":"Free Radical Mechanisms for the Treatment of Methyl Tert -Butyl Ether ( MTBE ) via Advanced Oxidation\/Reductive Processes in Aqueous Solutions","first-page":"1302","author":"Cooper","year":"2009"},{"key":"10.1016\/j.watres.2018.07.032_bib5","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.watres.2017.09.005","article-title":"Kinetic, product, and computational studies of the ultrasonic induced degradation of 4-methylcyclohexanemethanol (MCHM)","volume":"126","author":"Cui","year":"2017","journal-title":"Water Res."},{"key":"10.1016\/j.watres.2018.07.032_bib6","doi-asserted-by":"crossref","first-page":"7007","DOI":"10.1021\/ie300360p","article-title":"Effect of Fe(III)\/citrate concentrations and ratio on the photoproduction of hydroxyl radicals: application on the degradation of diphenhydramine","volume":"51","author":"Feng","year":"2012","journal-title":"Ind. Eng. Chem. Res."},{"key":"10.1016\/j.watres.2018.07.032_bib7","doi-asserted-by":"crossref","first-page":"2866","DOI":"10.1002\/etc.2378","article-title":"Acute and chronic effects of diphenhydramine and sertraline mixtures in Ceriodaphnia dubia","volume":"32","author":"Goolsby","year":"2013","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.watres.2018.07.032_bib8","series-title":"Organic Chemistry","author":"Graham Solomons","year":"2001"},{"key":"10.1016\/j.watres.2018.07.032_bib9","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.ultsonch.2010.03.008","article-title":"Degradation of diclofenac in water by homogeneous and heterogeneous sonolysis","volume":"18","author":"G\u00fcyer","year":"2011","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.watres.2018.07.032_bib10","doi-asserted-by":"crossref","first-page":"S163","DOI":"10.1016\/S1350-4177(96)00022-3","article-title":"Application of ultrasonic irradiation for the degradation of chemical contaminants in water","volume":"3","author":"Hoffmann","year":"1996","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.watres.2018.07.032_bib11","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1021\/j100008a015","article-title":"Sonolytic hydrolysis of p-nitrophenyl acetate: the role of supercritical water","volume":"99","author":"Hua","year":"1995","journal-title":"J.\u00a0Phys. Chem."},{"key":"10.1016\/j.watres.2018.07.032_bib12","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1007\/s00216-012-6144-y","article-title":"Pharmaceuticals in biota in the aquatic environment: analytical methods and environmental implications","volume":"404","author":"Huerta","year":"2012","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.watres.2018.07.032_bib13","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S1350-4177(02)00085-8","article-title":"Kinetics and mechanisms of ultrasonic degradation of volatile chlorinated aromatics in aqueous solutions","volume":"9","author":"Jiang","year":"2002","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.watres.2018.07.032_bib14","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S1350-4177(01)00114-6","article-title":"Effect of pH on the ultrasonic degradation of ionic aromatic compounds in aqueous solution","volume":"9","author":"Jiang","year":"2002","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.watres.2018.07.032_bib15","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.ultsonch.2011.12.003","article-title":"Mechanistic considerations for the degradation of methyl tert-butyl ether (MTBE) by sonolysis: effect of argon vs. oxygen saturated solutions","volume":"19","author":"Kim","year":"2012","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.watres.2018.07.032_bib16","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.ultsonch.2016.01.006","article-title":"Irradiation of ultrasound to 5-methylbenzotriazole in aqueous phase: degradation kinetics and mechanisms","volume":"31","author":"Kim","year":"2016","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.watres.2018.07.032_bib17","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1897\/05-187R.1","article-title":"Presence and distribution of wastewater-derived pharmaceuticals in soil irrigated with reclaimed water","volume":"25","author":"Kinney","year":"2006","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.watres.2018.07.032_bib18","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.envint.2008.07.009","article-title":"Removal of residual pharmaceuticals from aqueous systems by advanced oxidation processes","volume":"35","author":"Klavarioti","year":"2009","journal-title":"Environ. Int."},{"key":"10.1016\/j.watres.2018.07.032_bib19","first-page":"54","article-title":"The fundamentals of power ultrasound \u2013 a review","volume":"39","author":"Leong","year":"2011","journal-title":"Acoust Aust."},{"key":"10.1016\/j.watres.2018.07.032_bib20","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.jcis.2011.04.030","article-title":"Removal of diphenhydramine from water by swelling clay minerals","volume":"360","author":"Li","year":"2011","journal-title":"J.\u00a0Colloid Interface Sci."},{"key":"10.1016\/j.watres.2018.07.032_bib21","first-page":"119","volume":"vol. 72","author":"Louit","year":"2005"},{"key":"10.1016\/j.watres.2018.07.032_bib22","series-title":"Advances in Sonochemistry: V.6, Ultrasound in Environmental Protection","first-page":"273","author":"Mason","year":"2001"},{"key":"10.1016\/j.watres.2018.07.032_bib23","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1002\/jms.3607","article-title":"Identification of position isomers by energy-resolved mass spectrometry","volume":"50","author":"Menachery","year":"2015","journal-title":"J.\u00a0Mass Spectrom."},{"key":"10.1016\/j.watres.2018.07.032_bib24","series-title":"Transformation Reactions of Radicals from the Oxidation of Diphenhydramine\u202f: Pulse Radiolysis and Mass Spectrometric Studies","first-page":"924","author":"Menachery","year":"2016"},{"key":"10.1016\/j.watres.2018.07.032_bib25","first-page":"473","volume":"vol. 75","author":"Newton","year":"2006"},{"key":"10.1016\/j.watres.2018.07.032_bib26","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.ultsonch.2004.01.038","article-title":"Sonochemical degradation of azo dyes in aqueous solution: a new heterogeneous kinetics model taking into account the local concentration of OH radicals and azo dyes","volume":"12","author":"Okitsu","year":"2005","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.watres.2018.07.032_bib27","doi-asserted-by":"crossref","first-page":"4141","DOI":"10.1016\/j.scitotenv.2010.08.061","article-title":"Combination of Advanced Oxidation Processes and biological treatments for wastewater decontamination-A review","volume":"409","author":"Oller","year":"2011","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2018.07.032_bib28","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1021\/jz300929x","article-title":"Advanced oxidation processes for water treatment","volume":"3","author":"O'Shea","year":"2012","journal-title":"J.\u00a0Phys. Chem. Lett."},{"key":"10.1016\/j.watres.2018.07.032_bib29","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.apcatb.2011.11.041","article-title":"Degradation of diphenhydramine pharmaceutical in aqueous solutions by using two highly active TiO 2 photocatalysts: operating parameters and photocatalytic mechanism","volume":"113\u2013114","author":"Pastrana-Mart\u00ednez","year":"2012","journal-title":"Appl. Catal. B Environ."},{"key":"10.1016\/j.watres.2018.07.032_bib30","doi-asserted-by":"crossref","DOI":"10.1021\/jp003478y","article-title":"Sonolysis of 2,4-dichlorophenoxyacetic acid in aqueous solutions. Evidence for.OH-radical-mediated degradation","author":"Peller","year":"2001","journal-title":"J.\u00a0Phys. Chem. A"},{"key":"10.1016\/j.watres.2018.07.032_bib31","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S1350-4177(97)00039-4","article-title":"Sonochemical reactions at 640 kHz using an efficient reactor. Oxidation of potassium iodide","volume":"4","author":"Seymour","year":"1997","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.watres.2018.07.032_bib32","doi-asserted-by":"crossref","first-page":"54701","DOI":"10.1088\/1674-1056\/24\/5\/054701","article-title":"Effect of supercritical water shell on cavitation bubble dynamics","volume":"24","author":"Shao","year":"2015","journal-title":"Chin. Phys. B"},{"key":"10.1016\/j.watres.2018.07.032_bib33","first-page":"3338","article-title":"A\u00a0new mechanism for hydroxyl radical production in irradiated nanoparticle solutions","volume":"10","author":"Sicard-Roselli","year":"2014","journal-title":"Nanoparticle Solut"},{"key":"10.1016\/j.watres.2018.07.032_bib34","series-title":"Ultrasound Technology in Green Chemistry","first-page":"1","author":"Sillanp\u00e4\u00e4","year":"2011"},{"key":"10.1016\/j.watres.2018.07.032_bib35","doi-asserted-by":"crossref","first-page":"6300","DOI":"10.1021\/es048350z","article-title":"Ultrasonically induced degradation and detoxification of microcystin-LR (Cyanobacterial toxin)","volume":"39","author":"Song","year":"2005","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2018.07.032_bib36","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.watres.2008.11.018","article-title":"Free-radical-induced oxidative and reductive degradation of N,N\u2018-diethyl-m-toluamide (DEET): kinetic studies and degradation pathway","volume":"43","author":"Song","year":"2009","journal-title":"Water Res."},{"key":"10.1016\/j.watres.2018.07.032_bib37","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.scitotenv.2004.03.015","article-title":"Persistence of pharmaceutical compounds and other organic wastewater contaminants in a conventional drinking-water-treatment plant","volume":"329","author":"Stackelber","year":"2004","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2018.07.032_bib38","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/0041-624X(90)90033-K","article-title":"On the origin of sonoluminescence and sonochemistry","volume":"28","author":"Suslick","year":"1990","journal-title":"Ultrasonics"},{"key":"10.1016\/j.watres.2018.07.032_bib39","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1098\/rsta.1999.0330","article-title":"Acoustic cavitation and its chemical consequences","volume":"357","author":"Suslick","year":"1999","journal-title":"Phil. Trans. Roy. Soc. Lond."},{"key":"10.1016\/j.watres.2018.07.032_bib40","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1080\/09593330.2013.864711","article-title":"On the ultrasonic degradation of Rhodamine B in water\u202f: kinetics and operational conditions effect","volume":"35","author":"Taylor","year":"2014","journal-title":"Environ. Technol."},{"key":"10.1016\/j.watres.2018.07.032_bib41","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.scitotenv.2012.09.033","article-title":"The antihistamine diphenhydramine is extremely persistent in agricultural soil","volume":"439","author":"Topp","year":"2012","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2018.07.032_bib42","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/978-94-007-5533-8_2","article-title":"Advances in ultrasound technology for environmental remediation","author":"Wu","year":"2013","journal-title":"Adv. Ultrasound Technol. Environ. Remediat"},{"key":"10.1016\/j.watres.2018.07.032_bib43","doi-asserted-by":"crossref","first-page":"9675","DOI":"10.1021\/es5016197","article-title":"Kinetics and mechanism of sonochemical degradation of pharmaceuticals in municipal wastewater","volume":"48","author":"Xiao","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2018.07.032_bib44","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1016\/j.watres.2009.01.008","article-title":"Degradation of selected pharmaceuticals in aqueous solution with UV and UV\/H2O2","volume":"43","author":"Yuan","year":"2009","journal-title":"Water Res."}],"container-title":["Water Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004313541830575X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004313541830575X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T01:53:17Z","timestamp":1758592397000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004313541830575X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":44,"alternative-id":["S004313541830575X"],"URL":"https:\/\/doi.org\/10.1016\/j.watres.2018.07.032","relation":{},"ISSN":["0043-1354"],"issn-type":[{"value":"0043-1354","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fundamental study of the ultrasonic induced degradation of the popular antihistamine, diphenhydramine (DPH)","name":"articletitle","label":"Article Title"},{"value":"Water Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.watres.2018.07.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}