{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T04:03:01Z","timestamp":1793332981677,"version":"4.5.0"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,12]],"date-time":"2021-08-12T00:00:00Z","timestamp":1628726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011718","name":"Eawag ist das Wasserforschungsinstitut","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011718","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Water Research"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.watres.2021.117486","type":"journal-article","created":{"date-parts":[[2021,7,31]],"date-time":"2021-07-31T17:30:33Z","timestamp":1627752633000},"page":"117486","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":65,"special_numbering":"C","title":["Impact of wastewater on the microbial diversity of periphyton and its tolerance to micropollutants in an engineered flow-through channel system"],"prefix":"10.1016","volume":"203","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6576-0279","authenticated-orcid":false,"given":"Louis","family":"Carles","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2764-9216","authenticated-orcid":false,"given":"Simon","family":"Wullschleger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriano","family":"Joss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rik I.L.","family":"Eggen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1116-4724","authenticated-orcid":false,"given":"Kristin","family":"Schirmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nele","family":"Schuwirth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5888-6535","authenticated-orcid":false,"given":"Christian","family":"Stamm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Tlili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.watres.2021.117486_bib0001","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1104\/pp.71.2.388","article-title":"Effects of photosystem II herbicides on the photosynthetic membranes of the cyanobacterium Aphanocapsa 6308","volume":"71","author":"Allen","year":"1983","journal-title":"Plant Physiol."},{"key":"10.1016\/j.watres.2021.117486_bib0002","unstructured":"Andrews, S., 2010. FastQC: a quality control tool for high throughput sequence data [WWW Document]. URL http:\/\/www.bioinformatics.babraham.ac.uk\/projects\/fastqc."},{"key":"10.1016\/j.watres.2021.117486_bib0003","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1016\/j.scitotenv.2016.11.136","article-title":"Impact of wastewater treatment plant discharge on the contamination of river biofilms by pharmaceuticals and antibiotic resistance","volume":"579","author":"Aubertheau","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2021.117486_bib0004","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nrmicro.2016.15","article-title":"The ecology and biogeochemistry of stream biofilms","volume":"14","author":"Battin","year":"2016","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.watres.2021.117486_bib0005","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1127\/archiv-hydrobiol\/143\/1998\/147","article-title":"Periphyton development in three valley segments of a New Zealand grassland river: test of a habitat matrix conceptual model within a catchment","volume":"143","author":"Biggs","year":"1998","journal-title":"Fundamental Appl. Limnol."},{"key":"10.1016\/j.watres.2021.117486_bib0006","series-title":"Functional Testing of Aquatic Biota for Estimating Hazards of Chemicals","author":"Blanck","year":"1988"},{"key":"10.1016\/j.watres.2021.117486_bib0007","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/j.1574-6941.2009.00710.x","article-title":"Protists with different feeding modes change biofilm morphology: protists influence biofilm morphology","volume":"69","author":"B\u00f6hme","year":"2009","journal-title":"FEMS Microbiol. Ecol."},{"key":"10.1016\/j.watres.2021.117486_bib0008","series-title":"Role of Biofilms in Contaminant Bioaccumulation and Trophic Transfer in Aquatic Ecosystems: Current State of Knowledge and Future Challenges","author":"Bonnineau","year":"2020"},{"key":"10.1016\/j.watres.2021.117486_bib0009","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s00248-002-2036-6","article-title":"Incorporation of radiolabeled leucine into protein to estimate bacterial production in plant litter, sediment, epiphytic biofilms, and water samples","volume":"45","author":"Buesing","year":"2003","journal-title":"Microb. Ecol."},{"key":"10.1016\/j.watres.2021.117486_bib0010","doi-asserted-by":"crossref","DOI":"10.1111\/gcb.15302","article-title":"Stream microbial communities and ecosystem functioning show complex responses to multiple stressors in wastewater","author":"Burdon","year":"2020","journal-title":"Global Change Biol."},{"key":"10.1016\/j.watres.2021.117486_bib0011","doi-asserted-by":"crossref","first-page":"2639","DOI":"10.1038\/ismej.2017.119","article-title":"Exact sequence variants should replace operational taxonomic units in marker-gene data analysis","volume":"11","author":"Callahan","year":"2017","journal-title":"ISME J."},{"key":"10.1016\/j.watres.2021.117486_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.137463","article-title":"Interaction between glyphosate and dissolved phosphorus on bacterial and eukaryotic communities from river biofilms","volume":"719","author":"Carles","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2021.117486_bib0013","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1111\/j.1365-2427.2005.01401.x","article-title":"Bacteria and algae in stream periphyton along a nutrient gradient","volume":"50","author":"Carr","year":"2005","journal-title":"Freshwater Biol."},{"key":"10.1016\/j.watres.2021.117486_bib0014","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2019.00653","article-title":"Benthic diatom communities in an alpine river impacted by waste water treatment effluents as revealed using DNA metabarcoding","volume":"10","author":"Chonova","year":"2019","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.watres.2021.117486_bib0015","doi-asserted-by":"crossref","first-page":"9254","DOI":"10.1007\/s11356-017-0024-0","article-title":"River biofilm community changes related to pharmaceutical loads emitted by a wastewater treatment plant","volume":"25","author":"Chonova","year":"2018","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.watres.2021.117486_bib0016","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.chemosphere.2014.03.128","article-title":"Pollution-induced community tolerance to non-steroidal anti-inflammatory drugs (NSAIDs) in fluvial biofilm communities affected by WWTP effluents","volume":"112","author":"Corcoll","year":"2014","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2021.117486_bib0017","article-title":"Micropollutant Biotransformation and Bioaccumulation in Natural Stream biofilms","volume":"116846","author":"Desiante","year":"2021","journal-title":"Water Res."},{"key":"10.1016\/j.watres.2021.117486_bib0018","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1023\/A:1012598816581","article-title":"A pulse-amplitude modulated fluorescence-based method for assessing the effects of photosystem II herbicides on freshwater periphyton","volume":"13","author":"Dorigo","year":"2001","journal-title":"J. Appl. Phycol."},{"key":"10.1016\/j.watres.2021.117486_bib0019","article-title":"SINTAX: a simple non-Bayesian taxonomy classifier for 16S and ITS sequences (preprint)","author":"Edgar","year":"2016","journal-title":"Bioinformatics"},{"key":"10.1016\/j.watres.2021.117486_bib0020","unstructured":"FOEN, 2020. National river monitoring and survey programme (NADUF) [WWW Document]. URL https:\/\/www.bafu.admin.ch\/bafu\/en\/home\/themen\/thema-wasser\/wasser\u2013daten\u2013indikatoren-und-karten\/wasser\u2013messnetze\/nationale-beobachtung-oberflaechengewaesserqualitaet\u2013nawa-\/nationale-dauerbeobachtung-fliessgewaesser\u2013naduf-.html (accessed 6.10.20)."},{"key":"10.1016\/j.watres.2021.117486_bib0021","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1093\/pcp\/pcn021","article-title":"Biochemical bases for a widespread tolerance of cyanobacteria to the phosphonate herbicide glyphosate","volume":"49","author":"Forlani","year":"2008","journal-title":"Plant Cell Physiol."},{"key":"10.1016\/j.watres.2021.117486_bib0022","doi-asserted-by":"crossref","first-page":"4025","DOI":"10.1007\/s11356-014-3289-6","article-title":"Effects of mixtures of dissolved and particulate contaminants on phototrophic biofilms: new insights from a PICT approach combining toxicity tests with passive samplers and model substances","volume":"22","author":"Foulquier","year":"2015","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.watres.2021.117486_bib0023","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/ismej.2011.134","article-title":"Disconnect of microbial structure and function: enzyme activities and bacterial communities in nascent stream corridors","volume":"6","author":"Frossard","year":"2012","journal-title":"The ISME J."},{"key":"10.1016\/j.watres.2021.117486_bib0024","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1111\/fwb.12852","article-title":"Fostering integration of freshwater ecology with ecotoxicology","volume":"61","author":"Gessner","year":"2016","journal-title":"Freshwater Biol."},{"key":"10.1016\/j.watres.2021.117486_bib0025","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.4319\/lo.1987.32.6.1239","article-title":"Regulation of gross growth efficiency and ammonium regeneration in bacteria by substrate C: N ratio 1","volume":"32","author":"Goldman","year":"1987","journal-title":"Limnol. Oceanogr."},{"key":"10.1016\/j.watres.2021.117486_bib0026","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1111\/fwb.12797","article-title":"Influence of grazing on triclosan toxicity to stream periphyton","volume":"61","author":"Guasch","year":"2016","journal-title":"Freshwater Biol."},{"key":"10.1016\/j.watres.2021.117486_bib0027","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1038\/ismej.2011.41","article-title":"Transitions in bacterial communities along the 2000 km salinity gradient of the Baltic Sea","volume":"5","author":"Herlemann","year":"2011","journal-title":"ISME J."},{"key":"10.1016\/j.watres.2021.117486_bib0028","doi-asserted-by":"crossref","first-page":"e95567","DOI":"10.1371\/journal.pone.0095567","article-title":"Systematic design of 18s rRNA gene primers for determining eukaryotic diversity in microbial consortia","volume":"9","author":"Hugerth","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.watres.2021.117486_bib0029","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2016.01388","article-title":"Improving toxicity assessment of pesticide mixtures: the use of polar passive sampling devices extracts in microalgae toxicity tests","volume":"7","author":"Kim Tiam","year":"2016","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.watres.2021.117486_bib0030","doi-asserted-by":"crossref","first-page":"288","DOI":"10.2179\/18-163","article-title":"Photoautotrophic-periphyton composition in reaches with differing nutrient concentrations in the harpeth river of Middle Tennessee","volume":"83","author":"Lebkuecher","year":"2018","journal-title":"Castanea"},{"key":"10.1016\/j.watres.2021.117486_bib0031","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1093\/bioinformatics\/btr507","article-title":"FLASH: fast length adjustment of short reads to improve genome assemblies","volume":"27","author":"Mago\u010d","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.watres.2021.117486_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.135727","article-title":"Microbial community shifts in streams receiving treated wastewater effluent","volume":"709","author":"Mansfeldt","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2021.117486_bib0033","doi-asserted-by":"crossref","first-page":"10","DOI":"10.14806\/ej.17.1.200","article-title":"Cutadapt removes adapter sequences from high-throughput sequencing reads","volume":"17","author":"Martin","year":"2011","journal-title":"EMBnet.J."},{"key":"10.1016\/j.watres.2021.117486_bib0034","series-title":"pairwiseAdonis: Pairwise Multilevel Comparison Using Adonis","author":"Martinez Arbizu","year":"2020"},{"key":"10.1016\/j.watres.2021.117486_bib0035","doi-asserted-by":"crossref","first-page":"e61217","DOI":"10.1371\/journal.pone.0061217","article-title":"phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data","volume":"8","author":"McMurdie","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.watres.2021.117486_bib0036","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1080\/1080-700291905747","article-title":"Contaminant-adaptation and community tolerance in ecological risk assessment: introduction","volume":"8","author":"Millward","year":"2002","journal-title":"Human Ecol. Risk Assess.: Int. J."},{"key":"10.1016\/j.watres.2021.117486_bib0037","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s10750-010-0105-2","article-title":"The periphyton as a multimetric bioindicator for assessing the impact of land use on rivers: an overview of the Ardi\u00e8res-Morcille experimental watershed (France)","volume":"657","author":"Montuelle","year":"2010","journal-title":"Hydrobiologia"},{"key":"10.1016\/j.watres.2021.117486_bib0038","doi-asserted-by":"crossref","DOI":"10.3389\/fenvs.2018.00131","article-title":"A time-dose response model to assess diuron-induced photosynthesis inhibition in freshwater biofilms","volume":"6","author":"Morin","year":"2018","journal-title":"Front. Environ. Science"},{"key":"10.1016\/j.watres.2021.117486_bib0039","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1007\/s10646-012-0910-7","article-title":"Use of polar organic chemical integrative samplers to assess the effects of chronic pesticide exposure on biofilms","volume":"21","author":"Morin","year":"2012","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.watres.2021.117486_bib0040","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.watres.2014.12.043","article-title":"Evaluation of in-situ calibration of Chemcatcher passive samplers for 322 micropollutants in agricultural and urban affected rivers","volume":"71","author":"Moschet","year":"2015","journal-title":"Water Res."},{"key":"10.1016\/j.watres.2021.117486_bib0041","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.watres.2016.11.001","article-title":"Pesticides drive risk of micropollutants in wastewater-impacted streams during low flow conditions","volume":"110","author":"Munz","year":"2017","journal-title":"Water Res."},{"key":"10.1016\/j.watres.2021.117486_bib0042","doi-asserted-by":"crossref","first-page":"10347","DOI":"10.1021\/acs.est.8b03632","article-title":"Internal concentrations in Gammarids reveal increased risk of organic micropollutants in wastewater-impacted streams","volume":"52","author":"Munz","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2021.117486_bib0043","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0003-2670(00)88444-5","article-title":"A modified single solution method for the determination of phosphate in natural waters","volume":"27","author":"Murphy","year":"1962","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.watres.2021.117486_bib0044","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/1574-6941.12103","article-title":"Colonization of freshwater biofilms by nitrifying bacteria from activated sludge","volume":"85","author":"Mu\u00dfmann","year":"2013","journal-title":"FEMS Microbiol. Ecol."},{"key":"10.1016\/j.watres.2021.117486_bib0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.115254","article-title":"Impact of treated sewage effluent on the bacterial community composition in an intermittent mediterranean stream","volume":"266","author":"Pascual-Benito","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.watres.2021.117486_bib0046","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jes.2017.05.015","article-title":"Characteristics of microbial community involved in early biofilms formation under the influence of wastewater treatment plant effluent","volume":"66","author":"Peng","year":"2018","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.watres.2021.117486_bib0047","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.ecoenv.2018.11.103","article-title":"Immediate and legacy effects of urban pollution on river ecosystem functioning: a mesocosm experiment","volume":"169","author":"Pereda","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.watres.2021.117486_bib0048","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.envpol.2010.11.034","article-title":"Combining polar organic chemical integrative samplers (POCIS) with toxicity testing to evaluate pesticide mixture effects on natural phototrophic biofilms","volume":"159","author":"Pesce","year":"2011","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.watres.2021.117486_bib0049","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.watres.2014.08.053","article-title":"A review on emerging contaminants in wastewaters and the environment: current knowledge, understudied areas and recommendations for future monitoring","volume":"72","author":"Petrie","year":"2015","journal-title":"Water Res."},{"key":"10.1016\/j.watres.2021.117486_bib0050","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1016\/j.scitotenv.2017.09.162","article-title":"Wastewater treatment plant effluent introduces recoverable shifts in microbial community composition in receiving streams","volume":"613\u2013614","author":"Price","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2021.117486_bib0051","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.chemosphere.2013.01.063","article-title":"Response of biofilm bacterial communities to antibiotic pollutants in a Mediterranean river","volume":"92","author":"Proia","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2021.117486_bib0052","series-title":"The Influence of Organisms on the Composition of Seawater","first-page":"26","author":"Redfield","year":"1963"},{"key":"10.1016\/j.watres.2021.117486_bib0053","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.watres.2018.12.028","article-title":"Desiccation events change the microbial response to gradients of wastewater effluent pollution","volume":"151","author":"Romero","year":"2019","journal-title":"Water Res."},{"key":"10.1016\/j.watres.2021.117486_bib0054","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1111\/1365-2664.12146","article-title":"Multiple stressors in periphyton - comparison of observed and predicted tolerance responses to high ionic loads and herbicide exposure","volume":"50","author":"Rotter","year":"2013","journal-title":"J. Appl. Ecol."},{"key":"10.1016\/j.watres.2021.117486_bib0055","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1007\/s00216-006-1051-8","article-title":"Monitoring the effect of chemicals on biological communities. The biofilm as an interface","volume":"387","author":"Sabater","year":"2007","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.watres.2021.117486_bib0056","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/BF00031869","article-title":"Extraction of chlorophyll a from freshwater phytoplankton for spectrophotometric analysis","volume":"114","author":"Sartory","year":"1984","journal-title":"Hydrobiologia"},{"key":"10.1016\/j.watres.2021.117486_bib0057","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1093\/bioinformatics\/btr026","article-title":"Quality control and preprocessing of metagenomic datasets","volume":"27","author":"Schmieder","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.watres.2021.117486_bib0058","doi-asserted-by":"crossref","first-page":"e53445","DOI":"10.1371\/journal.pone.0053445","article-title":"Anilofos tolerance and its mineralization by the cyanobacterium Synechocystis sp. Strain PUPCCC 64","volume":"8","author":"Singh","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.watres.2021.117486_bib0059","series-title":"Unravelling the Impacts of Micropollutants in Aquatic Ecosystems","first-page":"183","author":"Stamm","year":"2016"},{"key":"10.1016\/j.watres.2021.117486_bib0060","doi-asserted-by":"crossref","first-page":"5567","DOI":"10.1111\/mec.14288","article-title":"Wastewater pollution differently affects the antibiotic resistance gene pool and biofilm bacterial communities across streambed compartments","volume":"26","author":"Subirats","year":"2017","journal-title":"Mol. Ecol."},{"key":"10.1016\/j.watres.2021.117486_bib0061","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1111\/fwb.12558","article-title":"Pollution-induced community tolerance (PICT): towards an ecologically relevant risk assessment of chemicals in aquatic systems","volume":"61","author":"Tlili","year":"2016","journal-title":"Freshwater Biol."},{"key":"10.1016\/j.watres.2021.117486_bib0062","doi-asserted-by":"crossref","first-page":"10745","DOI":"10.1021\/acs.est.0c02975","article-title":"Tolerance patterns in stream biofilms link complex chemical pollution to ecological impacts","volume":"54","author":"Tlili","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2021.117486_bib0063","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.aquatox.2008.02.004","article-title":"Responses of chronically contaminated biofilms to short pulses of diuron An experimental study simulating flooding events in a small river","volume":"87","author":"Tlili","year":"2008","journal-title":"Aquatic. Toxicol."},{"key":"10.1016\/j.watres.2021.117486_bib0064","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.watres.2017.01.016","article-title":"Micropollutant-induced tolerance of in situ periphyton: establishing causality in wastewater-impacted streams","volume":"111","author":"Tlili","year":"2017","journal-title":"Water Res."},{"key":"10.1016\/j.watres.2021.117486_bib0065","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.envpol.2010.09.033","article-title":"Use of the MicroRespTM method to assess pollution-induced community tolerance to metals for lotic biofilms","volume":"159","author":"Tlili","year":"2011","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.watres.2021.117486_bib0066","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1016\/j.scitotenv.2011.01.056","article-title":"Impact of chronic and acute pesticide exposures on periphyton communities","volume":"409","author":"Tlili","year":"2011","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2021.117486_bib0067","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3354\/ame01515","article-title":"Response of heterotrophic stream biofilm \u00adcommunities to a gradient of resources","volume":"64","author":"Van Horn","year":"2011","journal-title":"Aquat. Microb. Ecol."},{"key":"10.1016\/j.watres.2021.117486_bib0068","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/nature09440","article-title":"Global threats to human water security and river biodiversity","volume":"467","author":"V\u00f6r\u00f6smarty","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.watres.2021.117486_bib0069","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1002\/ecm.1315","article-title":"The food web perspective on aquatic biofilms","volume":"88","author":"Weitere","year":"2018","journal-title":"Ecol. Monogr."},{"key":"10.1016\/j.watres.2021.117486_bib0070","series-title":"Postharvest Physiology and Biochemistry of Fruits and Vegetables","first-page":"47","article-title":"Photosynthesis","author":"Yahia","year":"2019"}],"container-title":["Water Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0043135421006849?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0043135421006849?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T04:02:33Z","timestamp":1758600153000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0043135421006849"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":70,"alternative-id":["S0043135421006849"],"URL":"https:\/\/doi.org\/10.1016\/j.watres.2021.117486","relation":{},"ISSN":["0043-1354"],"issn-type":[{"value":"0043-1354","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of wastewater on the microbial diversity of periphyton and its tolerance to micropollutants in an engineered flow-through channel system","name":"articletitle","label":"Article Title"},{"value":"Water Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.watres.2021.117486","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"117486"}}