{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:04:30Z","timestamp":1790615070000,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100009467","name":"University of the Witwatersrand, Johannesburg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009467","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001336","name":"University of the Witwatersrand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004424","name":"Water Research Commission","doi-asserted-by":"publisher","award":["C2020\/2021-00568"],"award-info":[{"award-number":["C2020\/2021-00568"]}],"id":[{"id":"10.13039\/501100004424","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Water Research"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.watres.2022.119145","type":"journal-article","created":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T09:01:12Z","timestamp":1663923672000},"page":"119145","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Development and application of a membrane assisted solvent extraction-molecularly imprinted polymer based passive sampler for monitoring of selected pharmaceuticals in surface water"],"prefix":"10.1016","volume":"225","author":[{"given":"Sinegugu","family":"Khulu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somandla","family":"Ncube","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yannick","family":"Nuapia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence Mzukisi","family":"Madikizela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Mavhunga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke","family":"Chimuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.watres.2022.119145_bib0001","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1080\/00032719.2015.1033722","article-title":"Optimization of the temperature for the extraction of pharmaceuticals from wastewater by a hollow fiber silicone membrane","volume":"48","author":"Amdany","year":"2015","journal-title":"Anal. Lett."},{"key":"10.1016\/j.watres.2022.119145_bib0002","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.scitotenv.2014.02.082","article-title":"Application of polar organic chemical integrative sampler (POCIS) to monitor emerging contaminants in tropical waters","volume":"482\u2013483","author":"Bayen","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2022.119145_bib0003","doi-asserted-by":"crossref","first-page":"131","DOI":"10.2989\/16085914.2017.1347083","article-title":"Health effects in fish from the polluted Orlando Dam and Klipspruit wetland system , Soweto , South Africa Health effects in fish from the polluted Orlando Dam and Klipspruit wetland","volume":"42","author":"Bengu","year":"2017","journal-title":"Afr. J. Aquat. Sci."},{"key":"10.1016\/j.watres.2022.119145_bib0004","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1002\/etc.4160","article-title":"Review of atrazine sampling by polar organic chemical integrative samplers and Chemcatcher","volume":"37","author":"Booij","year":"2018","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.watres.2022.119145_bib0005","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.envpol.2012.01.038","article-title":"Occurrence and persistence of organic emerging contaminants and priority pollutants in five sewage treatment plants of Spain: Two years pilot survey monitoring","volume":"164","author":"Bueno","year":"2012","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.watres.2022.119145_bib0006","doi-asserted-by":"crossref","first-page":"5019","DOI":"10.1007\/s11356-014-3796-5","article-title":"POCIS passive samplers as a monitoring tool for pharmaceutical residues and their transformation products in marine environment","volume":"23","author":"Bueno","year":"2016","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.watres.2022.119145_bib0007","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.apsusc.2017.02.105","article-title":"New immobilisation protocol for the template used in solid-phase synthesis of MIP nanoparticles","volume":"406","author":"Chen","year":"2017","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.watres.2022.119145_bib0008","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.chroma.2010.12.019","article-title":"Selective extraction of triazine herbicides based on a combination of membrane assisted solvent extraction and molecularly imprinted solid phase extraction","volume":"1218","author":"Chimuka","year":"2011","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.watres.2022.119145_bib0009","doi-asserted-by":"crossref","first-page":"6272","DOI":"10.1021\/ac400432p","article-title":"Natural deep eutectic solvents as a new extraction media for phenolic metabolites in carthamus tinctorius L","volume":"85","author":"Dai","year":"2013","journal-title":"Anal. Chem."},{"key":"10.1016\/j.watres.2022.119145_bib0010","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1002\/etc.4225","article-title":"Effects of hydrodynamic conditions and temperature on polar organic chemical integrative sampling rates","volume":"37","author":"Djomte","year":"2018","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.watres.2022.119145_bib0011","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.scitotenv.2013.12.091","article-title":"A passive sampling method for detecting analgesics, psycholeptics, antidepressants and illicit drugs in aquatic environments in the Czech Republic","volume":"487","author":"Fedorova","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2022.119145_bib0012","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.talanta.2020.121316","article-title":"Study of passive sampler calibration ( Chemcatcher \u00ae ) for environmental monitoring of organotin compounds\u00a0: Matrix effect , concentration levels and laboratory vs in situ calibration","volume":"219","author":"Garnier","year":"2020","journal-title":"Talanta"},{"key":"10.1016\/j.watres.2022.119145_bib0013","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10408347.2019.1565983","article-title":"Critical reviews in analytical chemistry application of the polar organic chemical integrative sampler for isolation of environmental micropollutants \u2013 a review application of the polar organic chemical integrative sampler for isolation of environmental M","volume":"50","author":"Godlewska","year":"2020","journal-title":"Crit. Rev. Anal. Chem."},{"key":"10.1016\/j.watres.2022.119145_bib0014","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.gsd.2017.12.009","article-title":"Occurrence and fate of emerging contaminants in water environment: a review","volume":"6","author":"Gogoi","year":"2018","journal-title":"Groundw. Sustain. Dev."},{"key":"10.1016\/j.watres.2022.119145_bib0015","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1007\/s00289-021-03553-9","article-title":"Synthesis, characterization and application of a molecularly imprinted polymer as an adsorbent for solid-phase extraction of selected pharmaceuticals from water samples","volume":"79","author":"Khulu","year":"2022","journal-title":"Polym. Bull."},{"key":"10.1016\/j.watres.2022.119145_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.131973","article-title":"Multivariate optimization of a two-way technique for extraction of pharmaceuticals in surface water using a combination of membrane assisted solvent extraction and a molecularly imprinted polymer","volume":"286","author":"Khulu","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2022.119145_bib0017","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1146\/annurev-environ-052809-161223","article-title":"Pharmaceuticals in the environment","volume":"35","author":"K\u00fcmmerer","year":"2010","journal-title":"Annu. Rev. Environ. Resour."},{"key":"10.1016\/j.watres.2022.119145_bib0018","first-page":"80","article-title":"Detection of pharmaceutical and personal care products ( PPCPs ) in 3 maine lakes by synchronous-scan fluorescence spectroscopy ( SFS )","author":"Lausier","year":"2009","journal-title":"J. U.S. SJWP"},{"key":"10.1016\/j.watres.2022.119145_bib0019","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1021\/acs.est.6b05159","article-title":"Aquatic global passive sampling (AQUA-GAPS) revisited: first steps toward a network of networks for monitoring organic contaminants in the aquatic environment","volume":"51","author":"Lohmann","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2022.119145_bib0020","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.scitotenv.2019.07.052","article-title":"Anthropogenic contaminants of high concern: existence in water resources and their adverse effects","volume":"690","author":"L\u00f3pez-Pacheco","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2022.119145_bib0021","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1002\/etc.5265","article-title":"Target and suspect screening of pharmaceuticals and their transformation products in the Klip River, South Africa, using ultra-high\u2013performance liquid chromatography\u2013mass spectrometry","volume":"41","author":"Madikizela","year":"2022","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.watres.2022.119145_bib0022","doi-asserted-by":"crossref","first-page":"36724","DOI":"10.1007\/s11356-018-3602-x","article-title":"Synthesis of a molecularly imprinted polymer and its application in selective extraction of fenoprofen from wastewater","volume":"25","author":"Mbhele","year":"2018","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.watres.2022.119145_bib0023","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1080\/10408347.2016.1259063","article-title":"Calibration of passive samplers for the monitoring of pharmaceuticals in water-sampling rate variation","volume":"47","author":"M\u0119czykowska","year":"2017","journal-title":"Crit. Rev. Anal. Chem."},{"key":"10.1016\/j.watres.2022.119145_bib0024","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.aca.2011.03.045","article-title":"Analytica Chimica Acta Membrane assisted passive sampler for triazine compounds in water bodies \u2014 characterization of environmental conditions and field performance","volume":"694","author":"Nyoni","year":"2011","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.watres.2022.119145_bib0025","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.chroma.2006.03.115","article-title":"Potential of membrane-assisted solvent extraction for the determination of phosphoric acid triesters in wastewater samples by liquid chromatography \u2013 tandem mass spectrometry","volume":"1124","author":"Quintana","year":"2006","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.watres.2022.119145_bib0026","doi-asserted-by":"crossref","DOI":"10.1007\/s10661-019-7515-z","article-title":"Use of the chemcatcher\u00ae passive sampler and time-of-flight mass spectrometry to screen for emerging pollutants in rivers in Gauteng Province of South Africa","volume":"191","author":"Rimayi","year":"2019","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.watres.2022.119145_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2020.116108","article-title":"Deep eutectic solvents. The new generation of green solvents in analytical chemistry","volume":"134","author":"Santana-Mayor","year":"2021","journal-title":"TrAC - Trends Anal. Chem."},{"key":"10.1016\/j.watres.2022.119145_bib0028","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.microc.2017.07.015","article-title":"Application of deep eutectic solvents in analytical chemistry. A review","volume":"135","author":"Shishov","year":"2017","journal-title":"Microchem. J."},{"key":"10.1016\/j.watres.2022.119145_bib0029","doi-asserted-by":"crossref","first-page":"7325","DOI":"10.1007\/s00216-018-1346-6","article-title":"Evaluation of fatty acid\/alcohol-based hydrophobic deep eutectic solvents as media for extracting antibiotics from environmental water","volume":"410","author":"Tang","year":"2018","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.watres.2022.119145_bib0030","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1007\/s11814-016-0316-y","article-title":"Optimal separation of phenol from model oils by forming deep eutectic solvents with quaternary ammonium salts","volume":"34","author":"Tang","year":"2017","journal-title":"Korean J. Chem. Eng."},{"key":"10.1016\/j.watres.2022.119145_bib0031","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1080\/10408347.2019.1675043","article-title":"Applications for passive sampling of hydrophobic organic contaminants in water\u2014a review","volume":"51","author":"Taylor","year":"2021","journal-title":"Crit. Rev. Anal. Chem."},{"key":"10.1016\/j.watres.2022.119145_bib0032","doi-asserted-by":"crossref","unstructured":"Togola, A., Environ, J.A., Toxicol, C., 2007. Development of Polar Organic Integrative Samplers for Analysis of Pharmaceuticals in Aquatic Systems 79, 6734\u20136741.","DOI":"10.1021\/ac070559i"},{"key":"10.1016\/j.watres.2022.119145_bib0033","doi-asserted-by":"crossref","unstructured":"Verhagen, R., Kaserzon, S.L., Tscharke, B.J., Shukla, P., Clokey, J., Vrana, B., Thomas, K. V, Mueller, J.F., 2020. Time-Integrative Passive Sampling of Very Hydrophilic Chemicals in Wastewater In fl uent. https:\/\/doi.org\/10.1021\/acs.estlett.0c00685.","DOI":"10.1021\/acs.estlett.0c00685"},{"key":"10.1016\/j.watres.2022.119145_bib0034","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1039\/B710790K","article-title":"The role of hydrodynamics, matrix and sampling duration in passive sampling of polar compounds with EmporeTM SDB-RPS disks","volume":"10","author":"Vermeirssen","year":"2008","journal-title":"J. Environ. Monit."},{"key":"10.1016\/j.watres.2022.119145_bib0035","doi-asserted-by":"crossref","first-page":"6759","DOI":"10.1021\/es3007854","article-title":"Transfer kinetics of polar organic compounds over polyethersulfone membranes in the passive samplers pocis and chemcatcher","volume":"46","author":"Vermeirssen","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2022.119145_bib0036","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.trac.2005.06.006","article-title":"Passive sampling techniques for monitoring pollutants in water","volume":"24","author":"Vrana","year":"2005","journal-title":"TrAC - Trends Anal. Chem."},{"key":"10.1016\/j.watres.2022.119145_bib0037","doi-asserted-by":"crossref","unstructured":"Vrana, B., Fedorova, G., Svecov, H., Grabic, R., Golovko, O., 2021. In situ calibration of polar organic chemical integrative sampler ( POCIS ) for monitoring of pharmaceuticals in surface waters * 269. https:\/\/doi.org\/10.1016\/j.envpol.2020.116121.","DOI":"10.1016\/j.envpol.2020.116121"},{"key":"10.1016\/j.watres.2022.119145_bib0038","doi-asserted-by":"crossref","unstructured":"Vrana, B., Mills, G.A., Allan, I.J., Dominiak, E., Svensson, K., Knutsson, J., Morrison, G., Greenwood, R., 2005b. Passive sampling techniques for monitoring pollutants in water 24. https:\/\/doi.org\/10.1016\/j.trac.2005.06.006.","DOI":"10.1016\/j.trac.2005.06.006"},{"key":"10.1016\/j.watres.2022.119145_bib0039","doi-asserted-by":"crossref","first-page":"10415","DOI":"10.1007\/s11356-020-07616-8","article-title":"Development of quantitative structure-property relationship model for predicting the field sampling rate (R s) of Chemcatcher passive sampler","volume":"27","author":"Wang","year":"2020","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.watres.2022.119145_bib0040","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.crci.2016.09.006","article-title":"Synthesis and application of a molecularly imprinted polymer in the solid-phase extraction of ketoprofen from wastewater","volume":"20","author":"Zunngu","year":"2017","journal-title":"Comptes Rendus Chim"}],"container-title":["Water Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0043135422010910?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0043135422010910?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T04:26:32Z","timestamp":1758601592000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0043135422010910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":40,"alternative-id":["S0043135422010910"],"URL":"https:\/\/doi.org\/10.1016\/j.watres.2022.119145","relation":{},"ISSN":["0043-1354"],"issn-type":[{"value":"0043-1354","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development and application of a membrane assisted solvent extraction-molecularly imprinted polymer based passive sampler for monitoring of selected pharmaceuticals in surface water","name":"articletitle","label":"Article Title"},{"value":"Water Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.watres.2022.119145","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"119145"}}