{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:27:57Z","timestamp":1792099677426,"version":"4.4.0"},"reference-count":93,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,11]],"date-time":"2022-12-11T00:00:00Z","timestamp":1670716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011718","name":"Eidgen\u00f6ssische Anstalt f\u00fcr Wasserversorgung Abwasserreinigung und Gew\u00e4sserschutz","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011718","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010665","name":"H2020 Marie Sk\u0142odowska-Curie Actions","doi-asserted-by":"publisher","award":["898843"],"award-info":[{"award-number":["898843"]}],"id":[{"id":"10.13039\/100010665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["181975"],"award-info":[{"award-number":["181975"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Water Research"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.watres.2022.119484","type":"journal-article","created":{"date-parts":[[2022,12,11]],"date-time":"2022-12-11T23:16:56Z","timestamp":1670800616000},"page":"119484","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"special_numbering":"C","title":["Ozonation of lake water and wastewater: Identification of carbonous and nitrogenous carbonyl-containing oxidation byproducts by non-target screening"],"prefix":"10.1016","volume":"232","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9156-9080","authenticated-orcid":false,"given":"Joanna","family":"Houska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8938-0828","authenticated-orcid":false,"given":"Tarek","family":"Manasfi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Gebhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6852-8977","authenticated-orcid":false,"given":"Urs","family":"von Gunten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.watres.2022.119484_bib0001","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1080\/01919510008547213","article-title":"Influence of carbonate on the ozone\/hydrogen peroxide based advanced oxidation process for drinking water treatment","volume":"22","author":"Acero","year":"2000","journal-title":"Ozone Sci Eng"},{"key":"10.1016\/j.watres.2022.119484_bib0002","doi-asserted-by":"crossref","first-page":"4916","DOI":"10.1021\/es300039h","article-title":"Antioxidant properties of humic substances","volume":"46","author":"Aeschbacher","year":"2012","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0003","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.watres.2007.08.032","article-title":"N-nitrosodimethylamine (NDMA) formation during ozonation of dimethylamine-containing waters","volume":"42","author":"Andrzejewski","year":"2008","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0004","doi-asserted-by":"crossref","first-page":"11725","DOI":"10.1021\/acs.est.9b03007","article-title":"The role of dissolved organic matter composition in determining photochemical reactivity at the molecular level","volume":"53","author":"Berg","year":"2019","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0005","doi-asserted-by":"crossref","first-page":"4341","DOI":"10.1016\/j.watres.2011.05.034","article-title":"Occurrence and control of nitrogenous disinfection by-products in drinking water \u2013 A review","volume":"45","author":"Bond","year":"2011","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0006","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.watres.2017.10.036","article-title":"Evaluation of a full-scale wastewater treatment plant upgraded with ozonation and biological post-treatments: abatement of micropollutants, formation of transformation products and oxidation by-products","volume":"129","author":"Bourgin","year":"2018","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0007","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1039\/B513226F","article-title":"Arene cis-dihydrodiol formation: from biology to application","volume":"4","author":"Boyd","year":"2006","journal-title":"Org Biomol Chem"},{"key":"10.1016\/j.watres.2022.119484_bib0008","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1021\/es052020c","article-title":"Phenols and amine induced HO. generation during the initial phase of natural water ozonation","volume":"40","author":"Buffle","year":"2006","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0009","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1063\/1.555805","article-title":"Critical Review of rate constants for reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals (\u22c5OH\/\u22c5O\u2212) in Aqueous Solution","volume":"17","author":"Buxton","year":"1988","journal-title":"J Phys Chem Ref Data"},{"key":"10.1016\/j.watres.2022.119484_bib0010","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.watres.2015.05.039","article-title":"Combination of UV absorbance and electron donating capacity to assess degradation of micropollutants and formation of bromate during ozonation of wastewater effluents","volume":"81","author":"Chon","year":"2015","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0011","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/j.1551-8833.2009.tb09963.x","article-title":"Occurrence and removal of amino acids during drinking water treatment","volume":"101","author":"Dotson","year":"2009","journal-title":"J Am Water Works Assoc"},{"key":"10.1016\/j.watres.2022.119484_bib0012","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1039\/b907093a","article-title":"JEM Spotlight: monitoring the treatment efficiency of a full scale ozonation on a sewage treatment plant with a mode-of-action based test battery","volume":"11","author":"Escher","year":"2009","journal-title":"J. Environ. Monit."},{"key":"10.1016\/j.watres.2022.119484_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2021.117864","article-title":"Reactions of amines with ozone and chlorine: two novel oxidative methods to evaluate the N-DBP formation potential from dissolved organic nitrogen","volume":"209","author":"Essa\u00efed","year":"2022","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0014","doi-asserted-by":"crossref","first-page":"7242","DOI":"10.1021\/jp022455b","article-title":"Determination of \u00b7 OH, O2\u00b7-, and Hydroperoxide Yields in Ozone Reactions in Aqueous Solution","volume":"107","author":"Flyunt","year":"2003","journal-title":"J Phys Chem B"},{"key":"10.1016\/j.watres.2022.119484_bib0015","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1039\/b204067k","article-title":"The reactions of thymine and thymidine with ozone","volume":"2 2","author":"Flyunt","year":"2002","journal-title":"J. Chem. Soc., Perkin Trans."},{"key":"10.1016\/j.watres.2022.119484_bib0016","doi-asserted-by":"crossref","DOI":"10.1038\/nrmicro2652","article-title":"Microbial degradation of aromatic compounds- From one strategy to four","author":"Fuchs","year":"2011","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.watres.2022.119484_bib0017","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1289\/ehp.8669151","article-title":"Reaction products of ozone\u00a0: a review","volume":"69","author":"Glaze","year":"1986","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.watres.2022.119484_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2021.117812","article-title":"Oxidation of 51 micropollutants during drinking water ozonation: formation of transformation products and their fate during biological post-filtration","volume":"207","author":"Gulde","year":"2021","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0019","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/j.watres.2007.01.001","article-title":"Formation of assimilable organic carbon (AOC) and specific natural organic matter (NOM) fractions during ozonation of phytoplankton","volume":"41","author":"Hammes","year":"2007","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0020","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1016\/j.watres.2006.04.029","article-title":"Mechanistic and kinetic evaluation of organic disinfection by-product and assimilable organic carbon (AOC) formation during the ozonation of drinking water","volume":"40","author":"Hammes","year":"2006","journal-title":"Water Res"},{"issue":"2","key":"10.1016\/j.watres.2022.119484_bib94","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0043-1354(83)90098-2","article-title":"Rate constants of reactions of ozone with organic and inorganic compounds in water\u2014I: non-dissociating organic compounds","volume":"17","author":"Hoign\u00e9","year":"1983","journal-title":"Water Research"},{"key":"10.1016\/j.watres.2022.119484_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2021.117790","article-title":"Oxidant-reactive carbonous moieties in dissolved organic matter: selective quantification by oxidative titration using chlorine dioxide and ozone","volume":"207","author":"Houska","year":"2021","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0022","unstructured":"IHSS, 2020. International humic substances society [WWW Document]. http:\/\/www.humicsubstances.org."},{"key":"10.1016\/j.watres.2022.119484_bib0023","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1021\/acs.est.1c04310","article-title":"Discovery of polar ozonation byproducts via direct injection of effluent organic matter with online LC-FT-ICR-MS","volume":"56","author":"Jennings","year":"2022","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0024","doi-asserted-by":"crossref","first-page":"7763","DOI":"10.1021\/acs.est.8b00582","article-title":"Elucidating the elementary reaction pathways and kinetics of hydroxyl radical-induced acetone degradation in aqueous phase advanced oxidation processes","volume":"52","author":"Kamath","year":"2018","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0025","doi-asserted-by":"crossref","first-page":"95","DOI":"10.2166\/ws.2007.149","article-title":"Characterisation of carbonyl byproducts of drinking water ozonation","volume":"7","author":"Khan","year":"2007","journal-title":"Water Supply"},{"key":"10.1016\/j.watres.2022.119484_bib0026","doi-asserted-by":"crossref","first-page":"4077","DOI":"10.1098\/rsta.2009.0108","article-title":"The formation and control of emerging disinfection by-products of health concern","volume":"367","author":"Krasner","year":"2009","journal-title":"Philos. Trans. R. Soc. A: Math., Phys. Eng. Sci."},{"key":"10.1016\/j.watres.2022.119484_bib0027","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1021\/es940544z","article-title":"Reactions of ozone and hydroxyl radicals with serine","volume":"30","author":"le Lacheur","year":"1996","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0028","doi-asserted-by":"crossref","first-page":"6177","DOI":"10.1016\/j.watres.2012.06.006","article-title":"Quantitative structure\u2013activity relationships (QSARs) for the transformation of organic micropollutants during oxidative water treatment","volume":"46","author":"Lee","year":"2012","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0029","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1080\/01919510903041354","article-title":"Ozonolysis of unsaturated acids in aqueous solution: acrylic, methacrylic, maleic, fumaric and muconic acids","volume":"31","author":"Leitzke","year":"2009","journal-title":"Ozone Sci Eng"},{"key":"10.1016\/j.watres.2022.119484_bib0030","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1021\/acs.est.7b05440","article-title":"Drinking water disinfection byproducts (DBPs) and human health effects: multidisciplinary challenges and opportunities","volume":"52","author":"Li","year":"2018","journal-title":"Environ. Sci. Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2022.118053","article-title":"Ozonation of organic compounds in water and wastewater: a critical review","author":"Lim","year":"2022","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0032","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.chemosphere.2014.12.054","article-title":"Formation of aldehydes and carboxylic acids in ozonated surface water and wastewater: a clear relationship with fluorescence changes","volume":"125","author":"Liu","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2022.119484_bib0033","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1021\/acs.est.9b04875","article-title":"Characterization of carbonyl disinfection by-products during ozonation, chlorination and chloramination of dissolved organic matters","volume":"54","author":"Liu","year":"2020","journal-title":"Environ. Sci. Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0034","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1021\/tx5001046","article-title":"Molecular mechanisms of aldehyde toxicity: a chemical perspective","volume":"27","author":"Lopachin","year":"2014","journal-title":"Chem Res Toxicol"},{"key":"10.1016\/j.watres.2022.119484_bib0035","doi-asserted-by":"crossref","first-page":"10724","DOI":"10.1021\/ac502818e","article-title":"MS2Analyzer: a software for small molecule substructure annotations from accurate tandem mass spectra","volume":"86","author":"Ma","year":"2014","journal-title":"Anal Chem"},{"key":"10.1016\/j.watres.2022.119484_bib0036","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.watres.2017.05.055","article-title":"The effect of advanced secondary municipal wastewater treatment on the molecular composition of dissolved organic matter","volume":"122","author":"Maizel","year":"2017","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0037","doi-asserted-by":"crossref","unstructured":"Manasfi, T., Houska, J., Gebhardt, I., von Gunten, U., Formation of carbonyl compounds during ozonation of lake water and wastewater: development of a non-target screening method and quantification of target compounds, in revision for Water Research. 2023.","DOI":"10.1016\/j.watres.2023.119751"},{"key":"10.1016\/j.watres.2022.119484_bib0038","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0027-5107(99)00010-X","article-title":"Lipid peroxidation - DNA damage by malondialdehyde","volume":"424","author":"Marnett","year":"1999","journal-title":"Mutat. Res. \u2013 Fundam. Mol. Mech. Mutagen."},{"key":"10.1016\/j.watres.2022.119484_bib0039","doi-asserted-by":"crossref","first-page":"10895","DOI":"10.1021\/acs.est.0c02793","article-title":"Formation and fate of carbonyls in potable water reuse systems","volume":"54","author":"Marron","year":"2020","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0040","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1021\/acs.est.0c07660","article-title":"Reactions of \u03b1,\u03b2-unsaturated carbonyls with free chlorine, free bromine, and combined chlorine","volume":"55","author":"Marron","year":"2021","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0041","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1039\/b301824p","article-title":"Ozonolysis of phenols in aqueous solution","volume":"1","author":"Mvula","year":"2003","journal-title":"Org Biomol Chem"},{"key":"10.1016\/j.watres.2022.119484_bib0042","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1080\/713610650","article-title":"Influence of ozonation conditions on aldehyde and carboxylic acid formation","volume":"25","author":"Nawrocki","year":"2003","journal-title":"Ozone Sci Eng"},{"key":"10.1016\/j.watres.2022.119484_bib0043","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.watres.2018.06.059","article-title":"Ozone and chlorine reactions with dissolved organic matter - assessment of oxidant-reactive moieties by optical measurements and the electron donating capacities","volume":"144","author":"\u00d6nnby","year":"2018","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0044","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1061\/(ASCE)0733-9372(1994)120:4(727)","article-title":"Control of disinfection byproducts in drinking water","volume":"120","author":"Philip Singer","year":"1994","journal-title":"J. Environ. Eng."},{"key":"10.1016\/j.watres.2022.119484_bib0045","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.watres.2019.05.002","article-title":"Molecular characteristics of dissolved organic matter transformed by O3 and O3\/H2O2 treatments and the effects on formation of unknown disinfection by-products","volume":"159","author":"Phungsai","year":"2019","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0046","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.watres.2016.05.047","article-title":"Molecular characterization of low molecular weight dissolved organic matter in water reclamation processes using Orbitrap mass spectrometry","volume":"100","author":"Phungsai","year":"2016","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0047","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1002\/bbpc.19920961019","article-title":"tert-butanol as an OH-scavenger in the pulse radiolysis of oxygenated aqueous systems","volume":"96","author":"Piechowski","year":"1992","journal-title":"Berichte Bunsengesellsc. Phys. Chem."},{"key":"10.1016\/j.watres.2022.119484_bib0048","doi-asserted-by":"crossref","DOI":"10.1039\/D0EM00471E","article-title":"Reactivity-directed analysis-a novel approach for the identification of toxic organic electrophiles in drinking water","author":"Prasse","year":"2021","journal-title":"Environ Sci Process Impacts"},{"key":"10.1016\/j.watres.2022.119484_bib0049","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1073\/pnas.1715821115","article-title":"Unexpected transformation of dissolved phenols to toxic dicarbonyls by hydroxyl radicals and UV light","volume":"115","author":"Prasse","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.watres.2022.119484_bib0050","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.watres.2015.09.023","article-title":"Spoilt for choice: a critical review on the chemical and biological assessment of current wastewater treatment technologies","volume":"87","author":"Prasse","year":"2015","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0051","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1021\/acs.est.9b04926","article-title":"Chlorination of phenols revisited: unexpected formation of \u03b1,\u03b2-unsaturated C4-dicarbonyl ring cleavage products","volume":"54","author":"Prasse","year":"2020","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0052","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1016\/j.watres.2010.12.002","article-title":"Formation of assimilable organic carbon during oxidation of natural waters with ozone, chlorine dioxide, chlorine, permanganate, and ferrate","volume":"45","author":"Ramseier","year":"2011","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0053","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1080\/01919510902740477","article-title":"Mechanisms of phenol ozonation-kinetics of formation of primary and secondary reaction products","volume":"31","author":"Ramseier","year":"2009","journal-title":"Ozone Sci Eng"},{"key":"10.1016\/j.watres.2022.119484_bib0054","doi-asserted-by":"crossref","first-page":"10351","DOI":"10.1021\/acs.est.0c03052","article-title":"Molecular-level transformation of dissolved organic matter during oxidation by ozone and hydroxyl radical","volume":"54","author":"Remucal","year":"2020","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0055","first-page":"110","article-title":"Disinfection by-products: formation and occurrence in drinking water, in: encyclopedia of environmental health","author":"Richardson","year":"2011","journal-title":"Elsevier"},{"key":"10.1016\/j.watres.2022.119484_bib0056","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1021\/acs.analchem.9b05269","article-title":"Water analysis: emerging contaminants and current issues","volume":"92","author":"Richardson","year":"2019","journal-title":"Anal Chem"},{"key":"10.1016\/j.watres.2022.119484_bib0057","doi-asserted-by":"crossref","first-page":"3368","DOI":"10.1021\/es981218c","article-title":"Identification of new ozone disinfection byproducts in drinking water","volume":"33","author":"Richardson","year":"1999","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0058","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116418","article-title":"Efficiency of pre-oxidation of natural organic matter for the mitigation of disinfection byproducts: electron donating capacity and UV absorbance as surrogate parameters","volume":"187","author":"Roug\u00e9","year":"2020","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0059","first-page":"2382","article-title":"Comparison of the impact of ozone, chlorine dioxide, ferrate and permanganate pre-oxidation on organic disinfection byproduct formation during post-chlorination","volume":"6","author":"Roug\u00e9","year":"2020","journal-title":"Environ Sci (Camb)"},{"key":"10.1016\/j.watres.2022.119484_bib0060","doi-asserted-by":"crossref","first-page":"6340","DOI":"10.1021\/es7030467","article-title":"N,N-dimethylsulfamide as precursor for N-nitrosodimethylamine (NDMA) formation upon ozonation and its fate during drinking water treatment","volume":"42","author":"Schmidt","year":"2008","journal-title":"Environ Sci Technol"},{"issue":"17","key":"10.1016\/j.watres.2022.119484_bib95","doi-asserted-by":"crossref","first-page":"5698","DOI":"10.1021\/ja00225a019","article-title":"The rapid hydration of the acetyl radical. A pulse radiolysis study of acetaldehyde in aqueous solution","volume":"110","author":"Schuchmann","year":"1988","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.watres.2022.119484_bib0061","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1021\/es5002105","article-title":"Identifying small molecules via high resolution mass spectrometry: communicating confidence","volume":"48","author":"Schymanski","year":"2014","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0062","unstructured":"Service Chemical Abstracts, 2022. SciFinder [WWW Document]. URL https:\/\/scifinder.cas.org (accessed 2.22.22)."},{"key":"10.1016\/j.watres.2022.119484_bib0063","doi-asserted-by":"crossref","first-page":"6281","DOI":"10.1021\/acs.est.0c07895","article-title":"Formation and fate of nitromethane in ozone-based water reuse processes","volume":"55","author":"Shi","year":"2021","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0064","doi-asserted-by":"crossref","first-page":"5089","DOI":"10.1021\/ac500810r","article-title":"Integrated quantification and identification of aldehydes and ketones in biological samples","volume":"86","author":"Siegel","year":"2014","journal-title":"Anal Chem"},{"key":"10.1016\/j.watres.2022.119484_bib0065","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1600-0773.1950.tb03477.x","article-title":"A toxicologieal investigation of lower aliphatic aldehydes.: I. toxicity of formaldehyde, acetaldehyde, propionaldehyde and butyraldehyde; as well as of acrolein and crotonaldehyde","volume":"6","author":"Skog","year":"1950","journal-title":"Acta Pharmacol Toxicol (Copenh)"},{"key":"10.1016\/j.watres.2022.119484_bib0066","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1021\/es00142a012","article-title":"Decomposition of ozone in water in the presence of organic solutes acting as promoters and inhibitors of radical chain reactions","volume":"19","author":"Staehelin","year":"1985","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0067","first-page":"367","article-title":"Diversity of extradiol dioxygenases in aromatic-degrading microbial community explored using both culture-dependent and culture-independent approaches","volume":"90","author":"Suenaga","year":"2014","journal-title":"FEMS Microbiol Ecol"},{"key":"10.1016\/j.watres.2022.119484_bib0068","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.watres.2003.10.034","article-title":"Reactivity of natural organic matter fractions with chlorine dioxide and ozone","volume":"38","author":"\u015awietlik","year":"2004","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0069","first-page":"976","article-title":"Reactions of pyrrole, imidazole, and pyrazole with ozone: kinetics and mechanisms","volume":"6","author":"Tekle-R\u00f6ttering","year":"2020","journal-title":"Environ Sci (Camb)"},{"key":"10.1016\/j.watres.2022.119484_bib0070","doi-asserted-by":"crossref","first-page":"4763","DOI":"10.1021\/acs.est.8b00011","article-title":"Ozonation of para -substituted phenolic compounds yields p -benzoquinones, other cyclic \u03b1,\u03b2-unsaturated ketones, and substituted catechols","volume":"52","author":"Tentscher","year":"2018","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0071","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1039\/b009388m","article-title":"Rate constants of ozone reactions with DNA, its constituents and relatedcompounds","volume":"2","author":"Theruvathu","year":"2001","journal-title":"J. Chem. Soc., Perkin Trans."},{"key":"10.1016\/j.watres.2022.119484_bib0072","doi-asserted-by":"crossref","first-page":"8382","DOI":"10.1021\/es050941h","article-title":"Structure-dependent reactivity of low molecular weight fulvic acid molecules during ozonation","volume":"39","author":"These","year":"2005","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0073","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/0043-1354(87)90157-6","article-title":"Formation de chloropicrine en milieu aqueux: influence des nitrites sur la formation de precurseurs par oxydation de composes organiques","volume":"21","author":"Thibaud","year":"1987","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0074","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0891-5849(96)00617-X","article-title":"In vivo exposure to ozone depletes vitamins c and e and induces lipid peroxidation in epidermal layers of murine skin","volume":"23","author":"Thiele","year":"1997","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.watres.2022.119484_bib0075","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1080\/01919518908552443","article-title":"The effects of ozonation, biological filtration and distribution on the concentration of easily assimilable organic carbon (AOC) in drinking water","volume":"11","author":"van der Kooij","year":"1989","journal-title":"Ozone Sci Eng"},{"key":"10.1016\/j.watres.2022.119484_bib0076","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1007\/s002160051572","article-title":"Hydrazine reagents as derivatizing agents in environmental analysis - a critical review","volume":"366","author":"Vogel","year":"2000","journal-title":"Fresenius J Anal Chem"},{"key":"10.1016\/j.watres.2022.119484_bib0077","doi-asserted-by":"crossref","first-page":"7215","DOI":"10.1021\/acs.est.9b00570","article-title":"Systematic review of toxicity removal by advanced wastewater treatment technologies via ozonation and activated carbon","volume":"53","author":"V\u00f6lker","year":"2019","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0078","doi-asserted-by":"crossref","first-page":"5062","DOI":"10.1021\/acs.est.8b00586","article-title":"Oxidation processes in water treatment: are we on track?","volume":"52","author":"von Gunten","year":"2018","journal-title":"Environ. Sci. Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0079","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1016\/S0043-1354(02)00457-8","article-title":"Ozonation of drinking water: part I. Oxidation kinetics and product formation","volume":"37","author":"von Gunten","year":"2003","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0080","doi-asserted-by":"crossref","first-page":"5762","DOI":"10.1021\/es1011862","article-title":"Kinetics and mechanisms of N -nitrosodimethylamine formation upon ozonation of N, N -dimethylsulfamide-containing waters: bromide catalysis","volume":"44","author":"von Gunten","year":"2010","journal-title":"Environ Sci Technol"},{"issue":"4","key":"10.1016\/j.watres.2022.119484_bib93","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2166\/wst.1997.0074","article-title":"The fate of peroxyl radicals in aqueous solution","volume":"35","author":"von Sonntag","year":"1997","journal-title":"Water Sci. Technol."},{"key":"10.1016\/j.watres.2022.119484_bib0081","series-title":"Chemistry of Ozone in Water and Wastewater Treatment-From Basic Principles to Applications","author":"von Sonntag","year":"2012"},{"key":"10.1016\/j.watres.2022.119484_bib0082","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116235","article-title":"Quantification of the electron donating capacity and UV absorbance of dissolved organic matter during ozonation of secondary wastewater effluent by an assay and an automated analyzer","volume":"185","author":"Walpen","year":"2020","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0084","doi-asserted-by":"crossref","DOI":"10.1021\/ac990857i","article-title":"A call for analytical techniques to deter-mine unidentified disinfection byproducts in drinking water","author":"Weinberg","year":"1999","journal-title":"Analyt. Chem. News Features 801A-808A"},{"key":"10.1016\/j.watres.2022.119484_bib0085","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1016\/j.watres.2007.01.020","article-title":"Formation of oxidation byproducts from ozonation of wastewater","volume":"41","author":"Wert","year":"2007","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0086","doi-asserted-by":"crossref","first-page":"415","DOI":"10.2166\/aqua.2002.0038","article-title":"Dissolved organic nitrogen in drinking water supplies: a review","volume":"51","author":"Westerhoff","year":"2002","journal-title":"J. Water Supply: Res. Technol. - AQUA"},{"key":"10.1016\/j.watres.2022.119484_bib0087","first-page":"73","article-title":"Occurrence of free amino acids in the source waters of Zhejiang province, China, and their removal and transformation in drinking water systems","volume":"12","author":"Yang","year":"2020","journal-title":"Water (Basel)"},{"key":"10.1016\/j.watres.2022.119484_bib0088","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1039\/a904739e","article-title":"Production of OH radicals in the autoxidation of the Fe(II)-EDTA system","volume":"2","author":"Yurkova","year":"1999","journal-title":"J. Chem. Soc. Perkin Trans."},{"key":"10.1016\/j.watres.2022.119484_bib0089","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116484","article-title":"Unveiling the transformation of dissolved organic matter during ozonation of municipal secondary effluent based on FT-ICR-MS and spectral analysis","volume":"188","author":"Zhang","year":"2021","journal-title":"Water Res"},{"key":"10.1016\/j.watres.2022.119484_bib0090","doi-asserted-by":"crossref","first-page":"4857","DOI":"10.1021\/es7031423","article-title":"Formation of N-nitrosamines from eleven disinfection treatments of seven different surface waters","volume":"42","author":"Zhao","year":"2008","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.watres.2022.119484_bib0091","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2021.117487","article-title":"Aqueous ozonation of furans: kinetics and transformation mechanisms leading to the formation of \u03b1,\u03b2-unsaturated dicarbonyl compounds","volume":"203","author":"Zoumpouli","year":"2021","journal-title":"Water Res"}],"container-title":["Water Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0043135422014294?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0043135422014294?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T04:33:19Z","timestamp":1758601999000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0043135422014294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":93,"alternative-id":["S0043135422014294"],"URL":"https:\/\/doi.org\/10.1016\/j.watres.2022.119484","relation":{},"ISSN":["0043-1354"],"issn-type":[{"value":"0043-1354","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ozonation of lake water and wastewater: Identification of carbonous and nitrogenous carbonyl-containing oxidation byproducts by non-target screening","name":"articletitle","label":"Article Title"},{"value":"Water Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.watres.2022.119484","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"119484"}}