{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T21:19:57Z","timestamp":1793308797040,"version":"4.5.0"},"reference-count":78,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42077331"],"award-info":[{"award-number":["42077331"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52100027"],"award-info":[{"award-number":["52100027"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Water Research"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.watres.2024.122570","type":"journal-article","created":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T18:13:25Z","timestamp":1727892805000},"page":"122570","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"special_numbering":"PA","title":["Understanding the mechanism of microplastic-associated antibiotic resistance genes in aquatic ecosystems: Insights from metagenomic analyses and machine learning"],"prefix":"10.1016","volume":"268","author":[{"given":"Tengyi","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuicui","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3803-2847","authenticated-orcid":false,"given":"Wenxuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7574-4774","authenticated-orcid":false,"given":"Ming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9970-2701","authenticated-orcid":false,"given":"Zhiyuan","family":"Zong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bipeng","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"16","key":"10.1016\/j.watres.2024.122570_bib0001","doi-asserted-by":"crossref","first-page":"4814","DOI":"10.3390\/molecules26164814","article-title":"The impacts of different biological treatments on the transformation of explosives waste contaminated sludge","volume":"26","author":"Aburto-Medina","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.watres.2024.122570_bib0002","series-title":"Plant Pathology (Fifth Edition)","author":"Agrios","year":"2005"},{"key":"10.1016\/j.watres.2024.122570_bib0003","first-page":"517","article-title":"CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database","volume":"48","author":"Alcock","year":"2019","journal-title":"Nucl. Acid. Res."},{"key":"10.1016\/j.watres.2024.122570_bib0004","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.2147\/IDR.S173867","article-title":"Antibiotic resistance: a rundown of a global crisis","volume":"11","author":"Aslam","year":"2018","journal-title":"Infect. Drug Resist."},{"issue":"16","key":"10.1016\/j.watres.2024.122570_bib0005","doi-asserted-by":"crossref","first-page":"9033","DOI":"10.1021\/acs.est.8b01219","article-title":"Tracking the sources of antibiotic resistance genes in an urban stream during wet weather using shotgun metagenomic analyses","volume":"52","author":"Baral","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2024.122570_bib0006","doi-asserted-by":"crossref","first-page":"262","DOI":"10.3389\/fmars.2020.00262","article-title":"Major role of surrounding environment in shaping biofilm community composition on marine plastic debris","volume":"7","author":"Basili","year":"2020","journal-title":"Front. Mar. Sci."},{"issue":"20","key":"10.1016\/j.watres.2024.122570_bib0007","doi-asserted-by":"crossref","first-page":"15347","DOI":"10.1007\/s11356-014-4009-y","article-title":"Substrates specialization in lipid compounds and hydrocarbons of Marinobacter genus","volume":"22","author":"Bonin","year":"2015","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.watres.2024.122570_bib0008","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.polymdegradstab.2018.03.023","article-title":"Isolation and role of polylactic acid-degrading bacteria on degrading enzymes productions and PLA biodegradability at mesophilic conditions","volume":"152","author":"Bubpachat","year":"2018","journal-title":"Polym. Degrad. Stab."},{"key":"10.1016\/j.watres.2024.122570_bib0009","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.eurpolymj.2019.01.060","article-title":"Impact modification of PLA using biobased biodegradable PHA biopolymers","volume":"114","author":"Burzic","year":"2019","journal-title":"Eur. Polym. J."},{"issue":"10","key":"10.1016\/j.watres.2024.122570_bib0010","doi-asserted-by":"crossref","first-page":"18162","DOI":"10.3390\/ijms151018162","article-title":"Towards global QSAR model building for acute toxicity: munro database case study","volume":"15","author":"Chavan","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.watres.2024.122570_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.118284","article-title":"Enhanced propagation of intracellular and extracellular antibiotic resistance genes in municipal wastewater by microplastics","volume":"292","author":"Cheng","year":"2022","journal-title":"Environ. Pollut."},{"issue":"5","key":"10.1016\/j.watres.2024.122570_bib0012","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1093\/gigascience\/giaa046","article-title":"Global ocean resistome revealed: exploring antibiotic resistance gene abundance and distribution in TARA Oceans samples","volume":"9","author":"Cuadrat","year":"2020","journal-title":"Gigascience"},{"issue":"4","key":"10.1016\/j.watres.2024.122570_bib0013","doi-asserted-by":"crossref","DOI":"10.26508\/lsa.202302420","article-title":"Accessory genes define species-specific routes to antibiotic resistance","volume":"7","author":"Dillon","year":"2024","journal-title":"Life Sci. Alliance"},{"issue":"3","key":"10.1016\/j.watres.2024.122570_bib0014","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/femsec\/fiae019","article-title":"A metagenomic alpha-diversity index for microbial functional biodiversity","volume":"100","author":"Finn","year":"2024","journal-title":"FEMS Microbiol. Ecol."},{"issue":"9","key":"10.1016\/j.watres.2024.122570_bib0015","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1365\/s10337-010-1741-4","article-title":"QSRR models for Kov\u00e1ts\u2019 retention indices of a variety of volatile organic compounds on polar and apolar GC stationary phases using molecular connectivity indexes","volume":"72","author":"Ghavami","year":"2010","journal-title":"Chromatographia"},{"key":"10.1016\/j.watres.2024.122570_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128824","article-title":"Microplastics as vectors of the antibiotics azithromycin and clarithromycin: effects towards freshwater microalgae","volume":"268","author":"Gonz\u00e1lez-Pleiter","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2024.122570_bib0017","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.watres.2017.07.002","article-title":"Metagenomic analysis reveals wastewater treatment plants as hotspots of antibiotic resistance genes and mobile genetic elements","volume":"123","author":"Guo","year":"2017","journal-title":"Water Res."},{"key":"10.1016\/j.watres.2024.122570_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.156211","article-title":"Exploration of machine learning algorithms for predicting the changes in abundance of antibiotic resistance genes in anaerobic digestion","volume":"839","author":"Haffiez","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"3","key":"10.1016\/j.watres.2024.122570_bib0019","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1111\/j.1365-2672.2009.04471.x","article-title":"Stenotrophomonas and Lysobacter: ubiquitous plant-associated gamma-proteobacteria of developing significance in applied microbiology","volume":"108","author":"Hayward","year":"2010","journal-title":"J. Appl. Microbiol."},{"issue":"1","key":"10.1016\/j.watres.2024.122570_bib0020","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s40793-023-00489-7","article-title":"Identification of diverse antibiotic resistant bacteria in agricultural soil with H218O stable isotope probing combined with high-throughput sequencing","volume":"18","author":"Hern\u00e1ndez","year":"2023","journal-title":"Environ. Microbiom."},{"issue":"21","key":"10.1016\/j.watres.2024.122570_bib0021","doi-asserted-by":"crossref","first-page":"14948","DOI":"10.1021\/acs.est.2c00745","article-title":"Impact of plastic particles on the horizontal transfer of antibiotic resistance genes to bacterium: dependent on particle sizes and antibiotic resistance gene vector replication capacities","volume":"56","author":"Hu","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2024.122570_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121910","article-title":"The role of microplastic aging on chlorpyrifos adsorption-desorption and microplastic bioconcentration","volume":"331","author":"Ju","year":"2023","journal-title":"Environ. Pollut."},{"issue":"8","key":"10.1016\/j.watres.2024.122570_bib0023","doi-asserted-by":"crossref","first-page":"04639","DOI":"10.1016\/j.heliyon.2020.e04639","article-title":"Predicting novel drugs for SARS-CoV-2 using machine learning from a >10 million chemical space","volume":"6","author":"Kowalewski","year":"2020","journal-title":"Heliyon"},{"key":"10.1016\/j.watres.2024.122570_bib0024","series-title":"Trim Galore!: a Wrapper Around Cutadapt and FastQC to Consistently Apply Adapter and Quality Trimming to FastQ Files, with Extra Functionality for RRBS Data","author":"Krueger","year":"2015"},{"key":"10.1016\/j.watres.2024.122570_bib0025","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.jpba.2016.02.050","article-title":"Quantitative structure-(chromatographic) retention relationship models for dissociating compounds","volume":"127","author":"Kubik","year":"2016","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"1","key":"10.1016\/j.watres.2024.122570_bib0026","doi-asserted-by":"crossref","first-page":"15611","DOI":"10.1038\/ncomms15611","article-title":"River plastic emissions to the world's oceans","volume":"8","author":"Lebreton","year":"2017","journal-title":"Nat. Commun."},{"issue":"21","key":"10.1016\/j.watres.2024.122570_bib0027","doi-asserted-by":"crossref","first-page":"12227","DOI":"10.1021\/acs.est.9b03850","article-title":"Vertical distribution of microplastics in the water column and surficial sediment from the Milwaukee River Basin to Lake Michigan","volume":"53","author":"Lenaker","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2024.122570_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.133428","article-title":"Potential environmental risks of field bio\/non-degradable microplastic from mulching residues in farmland: evidence from metagenomic analysis of plastisphere","volume":"465","author":"Li","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.watres.2024.122570_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.158330","article-title":"Plastisphere showing unique microbiome and resistome different from activated sludge","volume":"851","author":"Li","year":"2022","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.watres.2024.122570_bib0030","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.ymeth.2019.04.008","article-title":"Deep learning in bioinformatics: introduction, application, and perspective in the big data era","volume":"166","author":"Li","year":"2019","journal-title":"Methods"},{"issue":"5","key":"10.1016\/j.watres.2024.122570_bib0031","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1007\/s10653-020-00759-0","article-title":"Impact factors of the accumulation, migration and spread of antibiotic resistance in the environment","volume":"43","author":"Lin","year":"2021","journal-title":"Environ. Geochem. Health"},{"key":"10.1016\/j.watres.2024.122570_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.enzmictec.2020.109719","article-title":"The polyhydroxyalkanoate (PHA) synthase 1 of Pseudomonas sp. H9 synthesized a 3-hydroxybutyrate-dominant hybrid of short- and medium-chain-length PHA","volume":"143","author":"Liu","year":"2021","journal-title":"Enzym. Microb. Technol."},{"key":"10.1016\/j.watres.2024.122570_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2019.109631","article-title":"Effects of microplastics on distribution of antibiotic resistance genes in recirculating aquaculture system","volume":"184","author":"Lu","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"33","key":"10.1016\/j.watres.2024.122570_bib0034","doi-asserted-by":"crossref","first-page":"12137","DOI":"10.1021\/acs.est.3c01128","article-title":"Determining the contribution of micro\/nanoplastics to antimicrobial resistance: challenges and perspectives","volume":"57","author":"Luo","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2024.122570_bib0035","doi-asserted-by":"crossref","first-page":"593","DOI":"10.3390\/ijms25010593","article-title":"Biodegradation of typical plastics: from microbial diversity to metabolic mechanisms","volume":"25","author":"Lv","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.watres.2024.122570_bib0036","article-title":"The usage of 10-fold cross-validation and grid search to enhance ML methods performance in solar farm power generation prediction","volume":"15","author":"Malakouti","year":"2023","journal-title":"Clean. Eng. Technol."},{"issue":"3","key":"10.1016\/j.watres.2024.122570_bib0037","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1055\/s-0042-1742423","article-title":"Molecular characterization of high-level aminoglycoside resistance among Enterococcus species","volume":"14","author":"Manoharan","year":"2022","journal-title":"J. Lab. Physic."},{"key":"10.1016\/j.watres.2024.122570_bib0038","doi-asserted-by":"crossref","first-page":"10","DOI":"10.14806\/ej.17.1.200","article-title":"Cutadapt removes adapter sequences from high-throughput sequencing reads","volume":"17","author":"Martin","year":"2011","journal-title":"EMBnet J."},{"key":"10.1016\/j.watres.2024.122570_bib0039","doi-asserted-by":"crossref","first-page":"11257","DOI":"10.1038\/ncomms11257","article-title":"Fast and sensitive taxonomic classification for metagenomics with Kaiju","volume":"7","author":"Menzel","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.watres.2024.122570_bib0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.168728","article-title":"Temporal dynamics of microbial composition and antibiotic resistome in fermentation bed culture pig farms across various ages","volume":"912","author":"Pan","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2024.122570_bib0041","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.ejbt.2019.04.005","article-title":"Development of biodegradation process for Poly(DL-lactic acid) degradation by crude enzyme produced by Actinomadura keratinilytica strain T16-1","volume":"40","author":"Panyachanakul","year":"2019","journal-title":"Electron. J. Biotechnol."},{"issue":"1","key":"10.1016\/j.watres.2024.122570_bib0042","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3390\/ijerph20010042","article-title":"Understanding the interplay between antimicrobial resistance, microplastics and xenobiotic contaminants: a leap towards one health?","volume":"20","author":"Piergiacomo","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"8\u20139","key":"10.1016\/j.watres.2024.122570_bib0043","article-title":"Intercorrelation limits in molecular descriptor preselection for QSAR\/QSPR","volume":"38","author":"R\u00e1cz","year":"2019","journal-title":"Mol. Inf."},{"issue":"1","key":"10.1016\/j.watres.2024.122570_bib0044","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1186\/s40168-017-0379-y","article-title":"Discovery of the fourth mobile sulfonamide resistance gene","volume":"5","author":"Razavi","year":"2017","journal-title":"Microbiome"},{"issue":"5","key":"10.1016\/j.watres.2024.122570_bib0045","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1021\/acs.estlett.0c00202","article-title":"Determining hosts of antibiotic resistance genes: a review of methodological advances","volume":"7","author":"Rice","year":"2020","journal-title":"Environ. Sci. Technol. Lett."},{"issue":"24","key":"10.1016\/j.watres.2024.122570_bib0046","doi-asserted-by":"crossref","first-page":"13976","DOI":"10.1021\/es403605f","article-title":"Polystyrene plastic: a source and sink for polycyclic aromatic hydrocarbons in the marine environment","volume":"47","author":"Rochman","year":"2013","journal-title":"Environ. Sci. Technol."},{"issue":"11","key":"10.1016\/j.watres.2024.122570_bib0047","first-page":"11794","article-title":"Raiders of the lost correlation: a guide on using Pearson and Spearman coefficients to detect hidden correlations in medical sciences","volume":"12","author":"Rovetta","year":"2020","journal-title":"Cureus"},{"key":"10.1016\/j.watres.2024.122570_bib0048","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.131200","article-title":"Dissemination of sulfonamide resistance genes in digester microbiome during anaerobic digestion of food waste leachate","volume":"452","author":"Saha","year":"2023","journal-title":"J. Hazard. Mater."},{"issue":"10","key":"10.1016\/j.watres.2024.122570_bib0049","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1177\/0734242X18785730","article-title":"Worldwide distribution and abundance of microplastic: how dire is the situation?","volume":"36","author":"Shahul Hamid","year":"2018","journal-title":"Waste Manage. Res."},{"key":"10.1016\/j.watres.2024.122570_bib0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclepro.2021.128188","article-title":"Microplastics act as an important protective umbrella for bacteria during water\/wastewater disinfection","volume":"315","author":"Shen","year":"2021","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.watres.2024.122570_bib0051","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.154596","article-title":"Biodegradable microplastics induced the dissemination of antibiotic resistance genes and virulence factors in soil: a metagenomic perspective","volume":"828","author":"Song","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2024.122570_bib0052","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112525","article-title":"Chemometric QSAR modeling of acute oral toxicity of Polycyclic Aromatic Hydrocarbons (PAHs) to rat using simple 2D descriptors and interspecies toxicity modeling with mouse","volume":"222","author":"Sun","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"22","key":"10.1016\/j.watres.2024.122570_bib0053","doi-asserted-by":"crossref","first-page":"13370","DOI":"10.1021\/acs.est.8b03853","article-title":"Bacterial survival strategies in an alkaline tailing site and the physiological mechanisms of dominant phylotypes as revealed by metagenomic analyses","volume":"52","author":"Sun","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2024.122570_bib0054","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2021.117384","article-title":"Predicting antibiotic resistance gene abundance in activated sludge using shotgun metagenomics and machine learning","volume":"202","author":"Sun","year":"2021","journal-title":"Water Res."},{"issue":"1","key":"10.1016\/j.watres.2024.122570_bib0055","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/ismeco\/ycad012","article-title":"Homogenization of bacterial plastisphere community in soil: a continental-scale microcosm study","volume":"4","author":"Sun","year":"2024","journal-title":"ISME Commun."},{"key":"10.1016\/j.watres.2024.122570_bib0056","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/978-1-0716-0195-2_8","article-title":"Bacterial differential expression analysis methods","volume":"2096","author":"Utturkar","year":"2020","journal-title":"Method. Mol. Biol."},{"issue":"9","key":"10.1016\/j.watres.2024.122570_bib0057","doi-asserted-by":"crossref","first-page":"4869","DOI":"10.1021\/es405721v","article-title":"Strong sorption of PCBs to nanoplastics, microplastics, carbon nanotubes, and fullerenes","volume":"48","author":"Velzeboer","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2024.122570_bib0058","article-title":"Microplastic biofilm: an important microniche that may accelerate the spread of antibiotic resistance genes via natural transformation","volume":"459","author":"Wang","year":"2023","journal-title":"J. Hazard. Mater."},{"issue":"19","key":"10.1016\/j.watres.2024.122570_bib0059","first-page":"12780","article-title":"Biofilm-developed microplastics as vectors of pollutants in aquatic environments","volume":"55","author":"Wang","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2024.122570_bib0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2022.118920","article-title":"Slower antibiotics degradation and higher resistance genes enrichment in plastisphere","volume":"222","author":"Wang","year":"2022","journal-title":"Water Res."},{"key":"10.1016\/j.watres.2024.122570_bib0061","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132952","article-title":"The pH-specific response of soil resistome to triclocarban and arsenic co-contamination","volume":"464","author":"Wang","year":"2024","journal-title":"J. Hazard. Mater."},{"issue":"4","key":"10.1016\/j.watres.2024.122570_bib0062","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s00128-023-03700-0","article-title":"Succession of bacteria attached to microplastics after transferring from a mariculture area to a seagrass meadow","volume":"110","author":"Wang","year":"2023","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.watres.2024.122570_bib0063","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.marpolbul.2019.06.005","article-title":"Zooplankton distribution and influencing factors in the South Yellow Sea in spring","volume":"146","author":"Wang","year":"2019","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.watres.2024.122570_bib0064","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2022.119192","article-title":"Deciphering the mechanisms shaping the plastisphere antibiotic resistome on riverine microplastics","volume":"225","author":"Xu","year":"2022","journal-title":"Water Res."},{"issue":"18","key":"10.1016\/j.watres.2024.122570_bib0065","doi-asserted-by":"crossref","first-page":"11322","DOI":"10.1021\/acs.est.0c04292","article-title":"Temporal dynamics of antibiotic resistome in the plastisphere during microbial colonization","volume":"54","author":"Yang","year":"2020","journal-title":"Environ. Sci. Technol."},{"issue":"18","key":"10.1016\/j.watres.2024.122570_bib0066","doi-asserted-by":"crossref","first-page":"10197","DOI":"10.1021\/es4017365","article-title":"Exploring variation of antibiotic resistance genes in activated sludge over a four-year period through a metagenomic approach","volume":"47","author":"Yang","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2024.122570_bib0067","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.envint.2018.11.061","article-title":"Plastics in the marine environment are reservoirs for antibiotic and metal resistance genes","volume":"123","author":"Yang","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.watres.2024.122570_bib0068","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.122522","article-title":"Physicochemical and biological changes on naturally aged microplastic surfaces in real environments over 10 months","volume":"337","author":"Yu","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.watres.2024.122570_bib0069","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.127895","article-title":"UV-aging of microplastics increases proximal ARG donor-recipient adsorption and leaching of chemicals that synergistically enhance antibiotic resistance propagation","volume":"427","author":"Yuan","year":"2022","journal-title":"J. Hazard. Mater."},{"issue":"1","key":"10.1016\/j.watres.2024.122570_bib0070","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1186\/s40168-023-01662-3","article-title":"Microbial hitchhikers harbouring antimicrobial-resistance genes in the riverine plastisphere","volume":"11","author":"Zadjelovic","year":"2023","journal-title":"Microbiome"},{"issue":"1","key":"10.1016\/j.watres.2024.122570_bib0071","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1080\/02664763.2011.578621","article-title":"Bias-corrected random forests in regression","volume":"39","author":"Zhang","year":"2012","journal-title":"J. Appl. Stat."},{"key":"10.1016\/j.watres.2024.122570_bib0072","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.watres.2016.01.010","article-title":"Impacts of addition of natural zeolite or a nitrification inhibitor on antibiotic resistance genes during sludge composting","volume":"91","author":"Zhang","year":"2016","journal-title":"Water Res."},{"key":"10.1016\/j.watres.2024.122570_bib0073","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2019.109852","article-title":"Potential risks of microplastics combined with superbugs: enrichment of antibiotic resistant bacteria on the surface of microplastics in mariculture system","volume":"187","author":"Zhang","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.watres.2024.122570_bib0074","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2023.136855","article-title":"Accelerating the discovery of N-annulated perylene organic sensitizers via an interpretable machine learning model","volume":"1296","author":"Zhang","year":"2024","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.watres.2024.122570_bib0075","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.watres.2018.01.063","article-title":"Antibiotic resistome in landfill leachate from different cities of China deciphered by metagenomic analysis","volume":"134","author":"Zhao","year":"2018","journal-title":"Water Res."},{"issue":"3","key":"10.1016\/j.watres.2024.122570_bib0076","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s10482-016-0646-0","article-title":"Pontibacter locisalis Sy30T sp. nov. isolated from soil collected from an abandoned saltern","volume":"109","author":"Zhou","year":"2016","journal-title":"Antonie Van Leeuwenhoek"},{"key":"10.1016\/j.watres.2024.122570_bib0077","doi-asserted-by":"crossref","first-page":"579","DOI":"10.3389\/fgene.2019.00579","article-title":"A review and tutorial of machine learning methods for microbiome host trait prediction","volume":"10","author":"Zhou","year":"2019","journal-title":"Front. Genet."},{"key":"10.1016\/j.watres.2024.122570_bib0078","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2023.120574","article-title":"Quantifying health risks of plastisphere antibiotic resistome and deciphering driving mechanisms in an urbanizing watershed","volume":"245","author":"Zhu","year":"2023","journal-title":"Water Res."}],"container-title":["Water Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0043135424014696?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0043135424014696?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T08:17:17Z","timestamp":1778660237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0043135424014696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":78,"alternative-id":["S0043135424014696"],"URL":"https:\/\/doi.org\/10.1016\/j.watres.2024.122570","relation":{},"ISSN":["0043-1354"],"issn-type":[{"value":"0043-1354","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Understanding the mechanism of microplastic-associated antibiotic resistance genes in aquatic ecosystems: Insights from metagenomic analyses and machine learning","name":"articletitle","label":"Article Title"},{"value":"Water Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.watres.2024.122570","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"122570"}}