{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:55:32Z","timestamp":1792169732784,"version":"4.4.0"},"reference-count":128,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2024M760442"],"award-info":[{"award-number":["2024M760442"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["GZC20240246"],"award-info":[{"award-number":["GZC20240246"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82404225"],"award-info":[{"award-number":["82404225"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Water Research"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.watres.2026.127114","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T23:17:08Z","timestamp":1791587828000},"page":"127114","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"PA","title":["Bacterial degradation of microcystins beyond parent-toxin loss: An evidence map of mechanisms, ecological constraints, and treatment validation"],"prefix":"10.1016","volume":"309","author":[{"given":"Qin","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolei","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongtong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuoxiao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongli","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihong","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuepu","family":"Pu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.watres.2026.127114_bib0001","first-page":"6552","article-title":"Biodegradation of microcystin by a new Bacillus sp. isolated from a Saudi freshwater lake","volume":"9","author":"Alamri","year":"2010","journal-title":"Afr. J. Biotechnol."},{"key":"10.1016\/j.watres.2026.127114_bib0002","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1007\/s10811-022-02701-6","article-title":"Promoting the simultaneous removal of Microcystis bloom and microcystin-RR by Bacillus sp. AK3 immobilized on floating porous glass pellets","volume":"34","author":"Boonbangkeng","year":"2022","journal-title":"J. Appl. Phycol."},{"key":"10.1016\/j.watres.2026.127114_bib0003","doi-asserted-by":"crossref","DOI":"10.1016\/j.toxicon.2025.108500","article-title":"Detection and quantification of microcystins in the mucilage of colonial cyanobacteria","volume":"265","author":"Bormans","year":"2025","journal-title":"Toxicon"},{"key":"10.1016\/j.watres.2026.127114_bib0004","doi-asserted-by":"crossref","first-page":"714","DOI":"10.3390\/toxins11120714","article-title":"Structural diversity, characterization and toxicology of microcystins","volume":"11","author":"Boua\u00efcha","year":"2019","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0005","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.watres.2006.01.022","article-title":"Biodegradation of the cyanobacterial toxin microcystin LR in natural water and biologically active slow sand filters","volume":"40","author":"Bourne","year":"2006","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0006","doi-asserted-by":"crossref","first-page":"4086","DOI":"10.1128\/aem.62.11.4086-4094.1996","article-title":"Enzymatic pathway for the bacterial degradation of the cyanobacterial cyclic peptide toxin microcystin LR","volume":"62","author":"Bourne","year":"1996","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.watres.2026.127114_bib0007","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1002\/tox.10013","article-title":"Characterisation of a gene cluster involved in bacterial degradation of the cyanobacterial toxin microcystin LR","volume":"16","author":"Bourne","year":"2001","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.watres.2026.127114_bib0008","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1007\/s00204-016-1913-6","article-title":"Cyanotoxins: producing organisms, occurrence, toxicity, mechanism of action and human health toxicological risk evaluation","volume":"91","author":"Buratti","year":"2017","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.watres.2026.127114_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113436","article-title":"The detoxification activities and mechanisms of microcystinase towards MC-LR","volume":"236","author":"Cai","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.watres.2026.127114_bib0010","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1002\/lno.12096","article-title":"Quantification of microcystin production and biodegradation rates in the western basin of Lake Erie","volume":"67","author":"Chaffin","year":"2022","journal-title":"Limnology & Oceanography"},{"key":"10.1016\/j.watres.2026.127114_bib0012","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1016\/j.watres.2009.11.025","article-title":"An effective pathway for the removal of microcystin LR via anoxic biodegradation in lake sediments","volume":"44","author":"Chen","year":"2010","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0011","first-page":"2527","article-title":"Anaerobic biodegradation of microcystin by bacterial community from sediment of Dianchi Lake","volume":"30","author":"Chen","year":"2009","journal-title":"Huan. Jing. Ke Xue"},{"key":"10.1016\/j.watres.2026.127114_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128139","article-title":"Treatment of microcystin (MC-LR) and nutrients in eutrophic water by constructed wetlands: performance and microbial community","volume":"263","author":"Cheng","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2026.127114_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2022.114669","article-title":"Removal of microcystin (MC-LR) in constructed wetlands integrated with microbial fuel cells: efficiency, bioelectricity generation and microbial response","volume":"309","author":"Cheng","year":"2022","journal-title":"J. Environ. Manage"},{"key":"10.1016\/j.watres.2026.127114_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116646","article-title":"Microcystinase \u2013 a review of the natural occurrence, heterologous expression, and biotechnological application of MlrA","volume":"189","author":"Dexter","year":"2021","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0016","doi-asserted-by":"crossref","first-page":"183","DOI":"10.3390\/toxins12030183","article-title":"Effects of microcystin-LR on metabolic functions and structure succession of sediment bacterial community under anaerobic conditions","volume":"12","author":"Ding","year":"2020","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0017","doi-asserted-by":"crossref","first-page":"536","DOI":"10.3390\/toxins10120536","article-title":"Further understanding of degradation pathways of microcystin-LR by an indigenous Sphingopyxis sp. in environmentally relevant pollution concentrations","volume":"10","author":"Ding","year":"2018","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0018","doi-asserted-by":"crossref","first-page":"446","DOI":"10.3390\/toxins17090446","article-title":"Comprehensive insight into microcystin-degrading mechanism of Sphingopyxis sp. m6 Based on Mlr enzymes","volume":"17","author":"Ding","year":"2025","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.118787","article-title":"Multiple pathways for the anaerobic biodegradation of microcystin-LR in the enriched microbial communities from Lake Taihu","volume":"297","author":"Ding","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.watres.2026.127114_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119947","article-title":"Microcystin-LR exposure enhances toxin-degrading capacity and reduces metabolic diversity of sediment microbial communities","volume":"311","author":"Ding","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.watres.2026.127114_bib0021","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.ecoenv.2017.07.046","article-title":"The biodegradation of microcystins in temperate freshwater bodies with previous cyanobacterial history","volume":"145","author":"Dziga","year":"2017","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.watres.2026.127114_bib0022","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1021\/tx300174e","article-title":"Verification of the Role of MlrC in microcystin biodegradation by studies using a heterologously expressed enzyme","volume":"25","author":"Dziga","year":"2012","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.watres.2026.127114_bib0023","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1021\/tx4000045","article-title":"Microbial degradation of microcystins","volume":"26","author":"Dziga","year":"2013","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.watres.2026.127114_bib0024","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.toxicon.2012.01.001","article-title":"Heterologous expression and characterisation of microcystinase","volume":"59","author":"Dziga","year":"2012","journal-title":"Toxicon"},{"key":"10.1016\/j.watres.2026.127114_bib0025","doi-asserted-by":"crossref","first-page":"76","DOI":"10.3390\/toxins8030076","article-title":"Characterization of enzymatic activity of MlrB and MlrC proteins involved in bacterial degradation of cyanotoxins microcystins","volume":"8","author":"Dziga","year":"2016","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0027","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1016\/j.chemosphere.2008.07.015","article-title":"Biodegradation of microcystins and nodularin in freshwaters","volume":"73","author":"Edwards","year":"2008","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2026.127114_bib0026","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1016\/j.toxicon.2010.02.020","article-title":"Biodegradation studies and sequencing of microcystin-LR degrading bacteria isolated from a drinking water biofilter and a fresh water lake","volume":"55","author":"Eleuterio","year":"2010","journal-title":"Toxicon"},{"key":"10.1016\/j.watres.2026.127114_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2022.118674","article-title":"Cyanopeptides restriction and degradation co-mediate microbiota assembly during a freshwater cyanobacterial harmful algal bloom (CyanoHAB)","volume":"220","author":"Gao","year":"2022","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0029","doi-asserted-by":"crossref","first-page":"402","DOI":"10.4257\/oeco.2009.1302.12","article-title":"Effects of different dissolved organic carbon concentrations and bacterial activity on biodegradation of microcystin (cyanotoxin)","volume":"13","author":"Gomes","year":"2009","journal-title":"Oecol. Bras."},{"key":"10.1016\/j.watres.2026.127114_bib0030","doi-asserted-by":"crossref","DOI":"10.1099\/ijsem.0.005659","article-title":"Shinella lacus sp. nov., a novel microcystin-degrading alphaproteobacterium containing the bla carbapenemase gene","volume":"72","author":"Gong","year":"2022","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"10.1016\/j.watres.2026.127114_bib0031","doi-asserted-by":"crossref","DOI":"10.1093\/ismeco\/ycae170","article-title":"Microcystin shapes the Microcystis phycosphere through community filtering and by influencing cross-feeding interactions","volume":"5","author":"Gro\u00dfe","year":"2025","journal-title":"ISMe Commun."},{"key":"10.1016\/j.watres.2026.127114_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.137866","article-title":"Crystal structural analysis and characterization for MlrC enzyme of Sphingomonas sp. ACM-3962 involved in linearized microcystin degradation","volume":"317","author":"Guo","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2026.127114_bib0033","article-title":"Structural insight into the substrate-binding mode and catalytic mechanism for MlrC enzyme of Sphingomonas sp. ACM-3962 in linearized microcystin biodegradation","volume":"14","author":"Guo","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.watres.2026.127114_bib0034","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.toxicon.2004.04.003","article-title":"Isolation of Adda from microcystin-LR by microbial degradation","volume":"44","author":"Harada","year":"2004","journal-title":"Toxicon"},{"key":"10.1016\/j.watres.2026.127114_bib0035","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1021\/tx8003517","article-title":"Further investigation of microbial degradation of microcystin using the advanced marfey method","volume":"22","author":"Hashimoto","year":"2009","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.watres.2026.127114_bib0036","article-title":"Microcystins in water: detection, microbial degradation strategies, and mechanisms","volume":"19","author":"He","year":"2022","journal-title":"IJERPH"},{"key":"10.1016\/j.watres.2026.127114_bib0037","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.toxicon.2007.03.021","article-title":"Bacterial degradation of microcystin toxins in drinking water eliminates their toxicity","volume":"50","author":"Ho","year":"2007","journal-title":"Toxicon"},{"key":"10.1016\/j.watres.2026.127114_bib0038","doi-asserted-by":"crossref","first-page":"4685","DOI":"10.1016\/j.watres.2007.06.057","article-title":"Isolation and identification of a novel microcystin-degrading bacterium from a biological sand filter","volume":"41","author":"Ho","year":"2007","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0039","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/j.watres.2005.12.009","article-title":"Bacterial degradation of microcystin toxins within a biologically active sand filter","volume":"40","author":"Ho","year":"2006","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0040","doi-asserted-by":"crossref","first-page":"4748","DOI":"10.1016\/S0043-1354(03)00413-5","article-title":"Degradation of microcystin in sediments at oxic and anoxic, denitrifying conditions","volume":"37","author":"Holst","year":"2003","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0041","doi-asserted-by":"crossref","first-page":"864","DOI":"10.3390\/toxins13120864","article-title":"Widespread distribution and adaptive degradation of microcystin degrader (mlr-Genotype) in Lake Taihu, China","volume":"13","author":"Hu","year":"2021","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0042","first-page":"4193","article-title":"Degradation of MC-LR in soil","volume":"36","author":"Huang","year":"2016","journal-title":"Acta Sci. Circumstantiae"},{"key":"10.1016\/j.watres.2026.127114_bib0043","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1080\/15287394.2019.1699345","article-title":"Anaerobic degradation of microcystin-LR by an indigenous bacterial Enterobacter sp. YF3","volume":"82","author":"Huang","year":"2019","journal-title":"J. Toxicol. Environ. Health A"},{"key":"10.1016\/j.watres.2026.127114_bib0044","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.137160","article-title":"Review: current understanding on biological filtration for the removal of microcystins","volume":"313","author":"Jeon","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2026.127114_bib0045","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/j.1574-6968.2011.02337.x","article-title":"Active and silent members in the mlr gene cluster of a microcystin-degrading bacterium isolated from Lake Taihu, China","volume":"322","author":"Jiang","year":"2011","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.watres.2026.127114_bib0046","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/0043-1354(94)90093-0","article-title":"Release and degradation of microcystin following algicide treatment of a Microcystis aeruginosa bloom in a recreational lake, as determined by HPLC and protein phosphatase inhibition assay","volume":"28","author":"Jones","year":"1994","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0047","first-page":"508","article-title":"Microcystin-LR biodegradation by Bacillus sp.: reaction rates and possible genes involved in the degradation","volume":"8","author":"Kansole","year":"2016","journal-title":"Water. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0048","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0111794","article-title":"Biodegradation of microcystins during gravity-driven membrane (GDM) ultrafiltration","volume":"9","author":"Kohler","year":"2014","journal-title":"PLoS. One"},{"key":"10.1016\/j.watres.2026.127114_bib0049","doi-asserted-by":"crossref","DOI":"10.1016\/j.hal.2020.101895","article-title":"Taxonomic and genotypical heterogeneity of microcystin degrading bacterioplankton in western Lake Erie","volume":"98","author":"Krishnan","year":"2020","journal-title":"Harmful. Algae"},{"key":"10.1016\/j.watres.2026.127114_bib0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2019.123090","article-title":"Co-culturing of native bacteria from drinking water treatment plant with known degraders to accelerate microcystin-LR removal using biofilter","volume":"383","author":"Kumar","year":"2020","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.watres.2026.127114_bib0051","doi-asserted-by":"crossref","first-page":"337","DOI":"10.3390\/toxins18080337","article-title":"Sphingopyxis sp. IM-1 reduces intact microcystin-LR and attenuates MC-LR-associated inflammatory gene expression in Hep3B hepatocytes","volume":"18","author":"Lad","year":"2026","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0052","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1021\/es00001a030","article-title":"Biotransformation of the cyanobacterial hepatotoxin microcystin-LR, as determined by HPLC and protein phosphatase bioassay","volume":"29","author":"Lam","year":"1995","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2026.127114_bib0053","doi-asserted-by":"crossref","first-page":"318","DOI":"10.3390\/toxins8110318","article-title":"Presence or absence of mlr genes and nutrient concentrations co-determine the microcystin biodegradation efficiency of a natural bacterial community","volume":"8","author":"Lezcano","year":"2016","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0054","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.117644","article-title":"Algicidal mechanism of Raoultella ornithinolytica against Microcystis aeruginosa: antioxidant response, photosynthetic system damage and microcystin degradation","volume":"287","author":"Li","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.watres.2026.127114_bib0055","doi-asserted-by":"crossref","first-page":"11903","DOI":"10.1021\/acs.est.6b03986","article-title":"Simultaneous Microcystis algicidal and microcystin degrading capability by a single Acinetobacter bacterial strain","volume":"50","author":"Li","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2026.127114_bib0058","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.scitotenv.2017.03.285","article-title":"Current research scenario for microcystins biodegradation \u2013 A review on fundamental knowledge, application prospects and challenges","volume":"595","author":"Li","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2026.127114_bib0056","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.biortech.2011.11.099","article-title":"Investigations into the biodegradation of microcystin-LR mediated by the biofilm in wintertime from a biological treatment facility in a drinking-water treatment plant","volume":"106","author":"Li","year":"2012","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.watres.2026.127114_bib0057","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.biochi.2025.01.005","article-title":"Structure and function analysis of microcystin transport protein MlrD","volume":"231","author":"Li","year":"2025","journal-title":"Biochimie"},{"key":"10.1016\/j.watres.2026.127114_bib0060","doi-asserted-by":"crossref","first-page":"333","DOI":"10.3390\/toxins14050333","article-title":"Genomic analysis of Sphingopyxis sp. USTB-05 for biodegrading cyanobacterial hepatotoxins","volume":"14","author":"Liu","year":"2022","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0061","doi-asserted-by":"crossref","first-page":"8811","DOI":"10.1021\/acs.est.0c02155","article-title":"Simultaneous microcystin degradation and Microcystis aeruginosa Inhibition with the single enzyme microcystinase A","volume":"54","author":"Liu","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2026.127114_bib0059","first-page":"496","article-title":"Biodegradation of Microcystin-RR by Sphingopyxis sp. and its influencing factors","volume":"51","author":"Liu","year":"2021","journal-title":"J. Southeast Univ. Nat. Sci. Ed."},{"key":"10.1016\/j.watres.2026.127114_bib0062","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1021\/acs.chemrestox.3c00341","article-title":"MlrA, an essential enzyme for microcystins and nodularin on first step biodegradation in microcystin-degrading bacteria","volume":"37","author":"Liu","year":"2024","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.watres.2026.127114_bib0063","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s00203-023-03554-4","article-title":"Evaluating the microcystin-LR-degrading potential of bacteria growing in extreme and polluted environments","volume":"205","author":"Lukhele","year":"2023","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.watres.2026.127114_bib0064","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0014-5793(90)80245-E","article-title":"Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants","volume":"264","author":"MacKintosh","year":"1990","journal-title":"FEBS Lett."},{"key":"10.1016\/j.watres.2026.127114_bib0065","doi-asserted-by":"crossref","first-page":"6924","DOI":"10.1128\/AEM.01928-09","article-title":"Isolation and identification of novel microcystin-degrading bacteria","volume":"75","author":"Manage","year":"2009","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.watres.2026.127114_bib0066","first-page":"1523","article-title":"The effect of organic carbon addition on the community structure and kinetics of microcystin-degrading bacterial consortia","volume":"10","author":"Manheim","year":"2018","journal-title":"Water. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0067","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.174745","article-title":"Saturated constructed wetlands for the remediation of cylindrospermopsin and microcystin-LR: plants, microbes, and biodegradation pathways","volume":"948","author":"Martinez I Quer","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2026.127114_bib0068","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s00248-002-3007-7","article-title":"Dynamics of microcystin-degrading bacteria in mucilage of Microcystis","volume":"46","author":"Maruyama","year":"2003","journal-title":"Microb. Ecol."},{"key":"10.1016\/j.watres.2026.127114_bib0069","doi-asserted-by":"crossref","first-page":"268","DOI":"10.3390\/toxins12040268","article-title":"A mini review on microcystins and bacterial degradation","volume":"12","author":"Massey","year":"2020","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0070","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.envint.2013.06.013","article-title":"State of knowledge and concerns on cyanobacterial blooms and cyanotoxins","volume":"59","author":"Merel","year":"2013","journal-title":"Environ. Int."},{"key":"10.1016\/j.watres.2026.127114_bib0071","doi-asserted-by":"crossref","first-page":"16372","DOI":"10.1021\/acs.est.3c05298","article-title":"Nature-based solution to eliminate cyanotoxins in water using biologically enhanced biochar","volume":"57","author":"Moore","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2026.127114_bib0072","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.139672","article-title":"Exploring microcystin-degrading bacteria thriving on recycled membranes during a cyanobacterial bloom","volume":"736","author":"Mor\u00f3n-L\u00f3pez","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2026.127114_bib0073","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclepro.2024.142187","article-title":"Innovative approaches for Microcystin removal: bacterioplankton biodegradation and multi-soil-layering system performance assessment","volume":"452","author":"Mugani","year":"2024","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.watres.2026.127114_bib0074","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2024.121497","article-title":"Unlocking the potential of bacterioplankton-mediated microcystin degradation and removal: a bibliometric analysis of sustainable water treatment strategies","volume":"255","author":"Mugani","year":"2024","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0075","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00203-024-04218-7","article-title":"Autoinducer-2 promotes microbial degradation of microcystin-LR by Leuconostoc mesenteroides BSH-02","volume":"207","author":"Ock","year":"2025","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.watres.2026.127114_bib0076","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2024.122241","article-title":"Insights into the interaction mechanisms between Microcystin-degrading bacteria and Microcystis aeruginosa","volume":"265","author":"Peng","year":"2024","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0077","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1186\/s40168-021-01140-8","article-title":"Single-colony sequencing reveals microbe-by-microbiome phylosymbiosis between the cyanobacterium Microcystis and its associated bacteria","volume":"9","author":"P\u00e9rez-Carrascal","year":"2021","journal-title":"Microbiome"},{"key":"10.1016\/j.watres.2026.127114_bib0078","doi-asserted-by":"crossref","DOI":"10.1093\/femsec\/fiae035","article-title":"The Microcystis -microbiome interactions: origins of the colonial lifestyle","volume":"100","author":"Piccini","year":"2024","journal-title":"FEMS. Microbiol. Ecol."},{"key":"10.1016\/j.watres.2026.127114_bib0079","doi-asserted-by":"crossref","first-page":"269","DOI":"10.3390\/toxins11050269","article-title":"Isolation of a novel microcystin-degrading bacterium and the evolutionary origin of mlr Gene cluster","volume":"11","author":"Qin","year":"2019","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0080","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1099\/ijs.0.63599-0","article-title":"Paucibacter toxinivorans gen. nov., sp. nov., a bacterium that degrades cyclic cyanobacterial hepatotoxins microcystins and nodularin","volume":"55","author":"Rapala","year":"2005","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"10.1016\/j.watres.2026.127114_bib0081","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s11157-014-9334-6","article-title":"The cyanotoxin-microcystins: current overview","volume":"13","author":"Rastogi","year":"2014","journal-title":"Rev. Environ. Sci. Biotechnol."},{"key":"10.1016\/j.watres.2026.127114_bib0082","doi-asserted-by":"crossref","first-page":"790","DOI":"10.3390\/toxins12120790","article-title":"Regulation efficacy and mechanism of the toxicity of microcystin-LR targeting protein phosphatase 1 via the biodegradation pathway","volume":"12","author":"Ren","year":"2020","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0083","doi-asserted-by":"crossref","first-page":"9647","DOI":"10.1021\/acs.est.5c16532","article-title":"Degradation of toxins and metabolites of cyanobacteria and micropollutants during biological sand filtration","volume":"60","author":"Roug\u00e9","year":"2026","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2026.127114_bib0084","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2023.120816","article-title":"Elucidating microbial mechanisms of microcystin-LR degradation in Lake Erie beach sand through metabolomics and metatranscriptomics","volume":"247","author":"Salter","year":"2023","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.hal.2024.102646","article-title":"Microcystin removal by microbial communities from a coastal lagoon: influence of abiotic factors, bacterioplankton composition and estimated functions","volume":"135","author":"Santos","year":"2024","journal-title":"Harmful. Algae"},{"key":"10.1016\/j.watres.2026.127114_bib0086","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1021\/acs.chemrestox.0c00164","article-title":"Microcystins: biogenesis, toxicity, analysis, and control","volume":"33","author":"Schreidah","year":"2020","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.watres.2026.127114_bib0087","doi-asserted-by":"crossref","first-page":"575","DOI":"10.3390\/microorganisms11030575","article-title":"Microcystin-detoxifying recombinant Saccharomyces cerevisiae expressing the mlrA gene from Sphingosinicella microcystinivorans B9","volume":"11","author":"Silva","year":"2023","journal-title":"Microorganisms"},{"key":"10.1016\/j.watres.2026.127114_bib0088","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.syapm.2017.11.009","article-title":"Priming of microbial microcystin degradation in biomass-fed gravity driven membrane filtration biofilms","volume":"41","author":"Silva","year":"2018","journal-title":"Syst. Appl. Microbiol."},{"key":"10.1016\/j.watres.2026.127114_bib0089","doi-asserted-by":"crossref","first-page":"fiz157","DOI":"10.1093\/femsec\/fiz157","article-title":"Priming of microcystin degradation in carbon-amended membrane biofilm communities is promoted by oxygen-limited conditions","volume":"95","author":"Silva","year":"2019","journal-title":"FEMS. Microbiol. Ecol."},{"key":"10.1016\/j.watres.2026.127114_bib0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.algal.2021.102244","article-title":"Bioinformatic analyses and enzymatic properties of microcystinase","volume":"55","author":"Sun","year":"2021","journal-title":"Algal. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0091","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1389235","article-title":"Enzymatic mechanism of MlrB for catalyzing linearized microcystins by Sphingopyxis sp. USTB-05","volume":"15","author":"Teng","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.watres.2026.127114_bib0092","doi-asserted-by":"crossref","first-page":"5275","DOI":"10.1021\/acsestwater.4c00308","article-title":"Identification of novel peptides originated from biodegradation of microcystins using UHPLC-HRMS\/MS","volume":"4","author":"Thenuwara","year":"2024","journal-title":"ACS EST Water"},{"key":"10.1016\/j.watres.2026.127114_bib0093","doi-asserted-by":"crossref","DOI":"10.1016\/j.hal.2023.102549","article-title":"Constructed wetland mesocosms improve the biodegradation of microcystin-LR and cylindrospermopsin by indigenous bacterial consortia","volume":"131","author":"Thyssen","year":"2024","journal-title":"Harmful. Algae"},{"key":"10.1016\/j.watres.2026.127114_bib0094","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2024.143436","article-title":"Biodegradation of microcystins by microbiota of duckweed Spirodela polyrhiza","volume":"366","author":"Toporowska","year":"2024","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2026.127114_bib0095","article-title":"Immobilized mixed bacterial communities as a sustainable strategy to curb harmful algal blooms: mesocosm investigations","author":"Tripathi","year":"2026","journal-title":"Environ. Sci.: Water Res. Technol."},{"key":"10.1016\/j.watres.2026.127114_bib0096","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2025.144783","article-title":"Immobilised native bacterial consortia for algal toxin removal: towards sustainable in-situ remediation","volume":"394","author":"Tripathi","year":"2026","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2026.127114_bib0097","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1504\/IJEWM.2009.026340","article-title":"Separated adsorption and bacterial degradation of microcystins in GAC filtration","volume":"3","author":"Wang","year":"2009","journal-title":"Int. J. Environ. Waste Manage"},{"key":"10.1016\/j.watres.2026.127114_bib0098","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.3389\/fmicb.2019.01750","article-title":"Microcystin-LR degradation and gene regulation of microcystin-degrading Novosphingobium sp. THN1 at different carbon concentrations","volume":"10","author":"Wang","year":"2019","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.watres.2026.127114_bib0099","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.126906","article-title":"Functional and structural analyses for MlrC enzyme of Novosphingobium sp. THN1 in microcystin-biodegradation: involving optimized heterologous expression, bioinformatics and site-directed mutagenesis","volume":"255","author":"Wang","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2026.127114_bib0100","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.chemosphere.2018.06.140","article-title":"Enhanced removal of Microcystis bloom and microcystin-LR using microcosm constructed wetlands with bioaugmentation of degrading bacteria","volume":"210","author":"Wang","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2026.127114_bib0101","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.3390\/microorganisms9081594","article-title":"Simultaneous removal of the freshwater bloom-forming cyanobacterium microcystis and cyanotoxin microcystins via combined use of algicidal bacterial filtrate and the microcystin-degrading enzymatic agent, MlrA","volume":"9","author":"Wang","year":"2021","journal-title":"Microorganisms"},{"key":"10.1016\/j.watres.2026.127114_bib0102","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.chemosphere.2015.12.067","article-title":"Influences of metal ions on microcystin-LR degradation capacity and dynamics in microbial distribution of biofilm collected from water treatment plant nearby Kasumigaura Lake","volume":"147","author":"Wang","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.watres.2026.127114_bib0103","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2024.118336","article-title":"Comparative genomic analysis and functional investigations for MCs catabolism mechanisms and evolutionary dynamics of MCs-degrading bacteria in ecology","volume":"248","author":"Wei","year":"2024","journal-title":"Environ. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0104","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1007\/s00216-010-3709-5","article-title":"A review of cyanobacteria and cyanotoxins removal\/inactivation in drinking water treatment","volume":"397","author":"Westrick","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.watres.2026.127114_bib0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113653","article-title":"Effect of the immobilized microcystin-LR-degrading enzyme MlrA on nodularin degradation and its immunotoxicity study","volume":"258","author":"Wu","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.watres.2026.127114_bib0106","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1021\/es103729m","article-title":"Mechanisms and factors affecting sorption of microcystins onto natural sediments","volume":"45","author":"Wu","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.watres.2026.127114_bib0107","doi-asserted-by":"crossref","DOI":"10.1016\/j.eti.2023.103440","article-title":"Biodegradation of microcystin using free and alginate-immobilized Stenotrophomonas geniculate DMC-X3 bacterium","volume":"32","author":"Xie","year":"2023","journal-title":"Environ. Technol. Innov."},{"key":"10.1016\/j.watres.2026.127114_bib0108","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2025.140565","article-title":"The coexistence of Bacillus haynesii and Bacillus tequilensis achieves synchronous algicidal activity and denitrification and enhances the MC-LR degradation of phycosphere microbiota","volume":"500","author":"Xing","year":"2025","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.watres.2026.127114_bib0109","doi-asserted-by":"crossref","first-page":"549","DOI":"10.3390\/toxins11100549","article-title":"Cloning and expression of genes for biodegrading Nodularin by Sphingopyxis sp. USTB-05","volume":"11","author":"Xu","year":"2019","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.115638","article-title":"A complete route for biodegradation of potentially carcinogenic cyanotoxin microcystin-LR in a novel indigenous bacterium","volume":"174","author":"Yang","year":"2020","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0111","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1080\/15287394.2018.1423803","article-title":"Microcystin-LR degradation utilizing a novel effective indigenous bacterial community YFMCD1 from Lake Taihu","volume":"81","author":"Yang","year":"2018","journal-title":"J. Toxicol. Environ. Health A"},{"key":"10.1016\/j.watres.2026.127114_bib0112","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.117721","article-title":"Comprehensive genomic and transcriptomic analyses of the anaerobic degradation of microcystin in Alcaligenes faecalis D04","volume":"290","author":"Yang","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.watres.2026.127114_bib0113","article-title":"Microcystin-degrading activity of an indigenous bacterial strain Stenotrophomonas acidaminiphila MC-LTH2 isolated from Lake Taihu","volume":"9","author":"Yang","year":"2014","journal-title":"PLoS. One"},{"key":"10.1016\/j.watres.2026.127114_bib0114","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1007\/s00343-024-4047-3","article-title":"Structural and functional analyses of microcystinase A: optimized heterologous expression, stability, and degradability","volume":"42","author":"Yang","year":"2024","journal-title":"J. Ocean. Limnol."},{"key":"10.1016\/j.watres.2026.127114_bib0115","first-page":"313","article-title":"Isolation, identification and characterization of a microcystin-degrading bacterium Paucibacter sp. strain CH","volume":"35","author":"You","year":"2014","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.watres.2026.127114_bib0116","doi-asserted-by":"crossref","first-page":"964","DOI":"10.3390\/ijerph20020964","article-title":"Regulation effectiveness and mechanism of biotransformation pathway on the toxicity of microcystin-LR target to protein phosphatase 2A","volume":"20","author":"Yu","year":"2023","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.watres.2026.127114_bib0117","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.123491","article-title":"Non-negligible inhibition effect of microcystin-LR biodegradation products target to protein phosphatase 2A","volume":"345","author":"Yu","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.watres.2026.127114_bib0118","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116092","article-title":"Two hierarchical LuxR-LuxI type quorum sensing systems in Novosphingobium activate microcystin degradation through transcriptional regulation of the mlr pathway","volume":"183","author":"Zeng","year":"2020","journal-title":"Water. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0119","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.145437","article-title":"Transcriptome analysis expands the potential roles of quorum sensing in biodegradation and physiological responses to microcystin","volume":"771","author":"Zeng","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.watres.2026.127114_bib0120","first-page":"775","article-title":"Efficiency and mechanisms of simultaneous removal of algae and microcystins in source water","volume":"30","author":"Zhan","year":"2010","journal-title":"Acta Sci. Circumstantiae"},{"key":"10.1016\/j.watres.2026.127114_bib0121","doi-asserted-by":"crossref","first-page":"573","DOI":"10.3390\/toxins14080573","article-title":"Immobilization of microbes for biodegradation of microcystins: a mini review","volume":"14","author":"Zhang","year":"2022","journal-title":"Toxins. (Basel)"},{"key":"10.1016\/j.watres.2026.127114_bib0122","doi-asserted-by":"crossref","first-page":"3044","DOI":"10.1021\/acsestwater.3c00240","article-title":"Immobilization of microcystin by the hydrogel\u2013biochar composite to enhance biodegradation during drinking water treatment","volume":"3","author":"Zhang","year":"2023","journal-title":"ACS EST Water"},{"key":"10.1016\/j.watres.2026.127114_bib0123","doi-asserted-by":"crossref","first-page":"745","DOI":"10.3724\/SP.J.1145.2012.00745","article-title":"Isolation and influencing factors of lactic acid bacteria with Microcystin-LR degradation ability","volume":"18","author":"Zhang","year":"2012","journal-title":"Chin. J. Appl. Environ. Biol."},{"key":"10.1016\/j.watres.2026.127114_bib0124","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1080\/15287394.2024.2438837","article-title":"Isolation and identification of a native bacterium Citrobacter farmeri against microcystin-LR in anaerobic environments","volume":"88","author":"Zhang","year":"2025","journal-title":"J. Toxicol. Environ. Health A"},{"key":"10.1016\/j.watres.2026.127114_bib0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2025.138479","article-title":"Quorum sensing regulates the efficiency of a microcystin-degrading microbial consortium","volume":"494","author":"Zhou","year":"2025","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.watres.2026.127114_bib0126","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/j.envpol.2019.02.013","article-title":"A novel pathway for the anaerobic biotransformation of microcystin-LR using enrichment cultures","volume":"247","author":"Zhu","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.watres.2026.127114_bib0127","doi-asserted-by":"crossref","first-page":"26020","DOI":"10.1007\/s11356-018-2676-9","article-title":"Regulation on the toxicity of microcystin-LR target to protein phosphatase 1 by biotransformation pathway: effectiveness and mechanism","volume":"25","author":"Zong","year":"2018","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.watres.2026.127114_bib0128","doi-asserted-by":"crossref","first-page":"602","DOI":"10.3390\/toxins14090602","article-title":"Purification and mechanism of microcystinase MlrC for catalyzing linearized cyanobacterial hepatotoxins using Sphingopyxis sp. USTB-05","volume":"14","author":"Zou","year":"2022","journal-title":"Toxins. (Basel)"}],"container-title":["Water Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0043135426017859?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0043135426017859?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:38:13Z","timestamp":1792168693000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0043135426017859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":128,"alternative-id":["S0043135426017859"],"URL":"https:\/\/doi.org\/10.1016\/j.watres.2026.127114","relation":{},"ISSN":["0043-1354"],"issn-type":[{"value":"0043-1354","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bacterial degradation of microcystins beyond parent-toxin loss: An evidence map of mechanisms, ecological constraints, and treatment validation","name":"articletitle","label":"Article Title"},{"value":"Water Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.watres.2026.127114","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"127114"}}