{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:46:32Z","timestamp":1790628392118,"version":"4.1.0"},"reference-count":35,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Wilderness &amp; Environmental Medicine"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:p>The objective of this case series was to describe 2 patients presenting with subarachnoid hemorrhage with hydrocephalus and hemoventricle after a snakebite caused by presumed Bothrops ssp. Both cases occurred in the municipality of Guajar\u00e1 (Amazonas state), Western Brazilian Amazon. Both cases featured delay in administration of serum therapy, which may have contributed to the emergence of complications such as stroke. Patient 1 was admitted to hospital 16 h after the snakebite occurred. Before receiving antivenom, testing showed the patient as having unclottable blood. She developed hemorrhagic stroke (a subarachnoid hemorrhage with hydrocephalus and hemoventricle). On the seventh day, she was discharged from hospital. Patient 2 arrived at the hospital 3 d after the snakebite occurred and presented with unclottable blood. He had a stroke (right frontoparietal hemorrhage, intraparenchymal hemorrhage already open to the ventricle) and died on the eighth day after the snakebite. Delay in seeking health care after snake envenomation can result in worse outcome.<\/jats:p>","DOI":"10.1016\/j.wem.2020.04.009","type":"journal-article","created":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T01:49:47Z","timestamp":1597974587000},"page":"337-343","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Cerebrovascular Accidents Related to Snakebites in the Amazon\u2014Two Case Reports"],"prefix":"10.1177","volume":"31","author":[{"given":"Jacqueline de Almeida Gon\u00e7alves","family":"Sachett","sequence":"first","affiliation":[{"name":"Universidade do Estado do Amazonas, Manaus, Brazil"},{"name":"Funda\u00e7\u00e3o de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ageane","family":"Mota da Silva","sequence":"additional","affiliation":[{"name":"Instituto Federal do Acre, Campus de Cruzeiro do Sul, Cruzeiro do Sul, Brazil"},{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o Bionorte\u2013Universidade Federal do Acre\u2013UFAC, Campus Universit\u00e1rio\u2013BR 364, Rio Branco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alba Waldilene Coelho Batista","family":"Dantas","sequence":"additional","affiliation":[{"name":"Hospital Regional do Juru\u00e1, Cruzeiro do Sul, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theobaldo Rebou\u00e7as","family":"Dantas","sequence":"additional","affiliation":[{"name":"Hospital Regional do Juru\u00e1, Cruzeiro do Sul, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f4nica","family":"Colombini","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Imunopatologia, Instituto Butantan, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Maria","family":"Moura da Silva","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Imunopatologia, Instituto Butantan, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wuelton Marcelo","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Universidade do Estado do Amazonas, Manaus, Brazil"},{"name":"Funda\u00e7\u00e3o de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo S\u00e9rgio","family":"Bernarde","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Herpetologia, Centro Multidisciplinar, Campus Floresta, Universidade Federal do Acre, Cruzeiro do Sul, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,9,1]]},"reference":[{"key":"bibr1-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2018.06.070"},{"issue":"5","key":"bibr2-j.wem.2020.04.009","volume":"9","author":"Wen F.H.","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"key":"bibr3-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(03)00005-1"},{"key":"bibr4-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46651992000400013"},{"key":"bibr5-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1590\/S0104-42301998000400010"},{"key":"bibr6-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0202361"},{"key":"bibr7-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002442"},{"key":"bibr8-j.wem.2020.04.009","first-page":"130","volume-title":"Serpientes venenosas: lecciones aprendidas desde Colombia","author":"Ca\u00f1as C.","year":"2016","edition":"1"},{"key":"bibr9-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1016\/j.wem.2019.04.003"},{"key":"bibr10-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000061614.52580.A1"},{"key":"bibr11-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2017.08.021"},{"key":"bibr12-j.wem.2020.04.009","volume-title":"Reatividade antig\u00eanica cruzada entre os venenos de Bothrops atrox e Lachesis muta muta e desenvolvimento de um teste imunoenzim\u00e1tico diferencial para acidentes causados por essas serpentes","author":"Colombini M.","year":"2003"},{"key":"bibr13-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000069"},{"issue":"1","key":"bibr14-j.wem.2020.04.009","first-page":"39","volume":"1","author":"Gagliardi R.J.","year":"2001","journal-title":"Acad Bras Neurol Rev Neuroci\u00eancias."},{"key":"bibr15-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1017\/cjn.2018.328"},{"key":"bibr16-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2016.08.005"},{"key":"bibr17-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-282X2007000200030"},{"key":"bibr18-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86822010000500029"},{"key":"bibr19-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.15344\/2456-8007\/2019\/133"},{"key":"bibr20-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-0101(00)00139-2"},{"key":"bibr21-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.15381\/anales.v64i3.1439"},{"key":"bibr22-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1021\/bi00583a021"},{"issue":"3","key":"bibr23-j.wem.2020.04.009","first-page":"241","volume":"31","author":"Rosing J.","year":"2001","journal-title":"Haemostasis"},{"key":"bibr24-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1648475"},{"key":"bibr25-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-20790-2_119-1"},{"key":"bibr26-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.3390\/toxins11010022"},{"key":"bibr27-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2017.04.013"},{"key":"bibr28-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1016\/0041-0101(91)90116-9"},{"key":"bibr29-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2017.03.003"},{"key":"bibr30-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0208532"},{"key":"bibr31-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0050218"},{"key":"bibr32-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0115-2019"},{"key":"bibr33-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1186\/s40409-015-0052-5"},{"key":"bibr34-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0132237"},{"key":"bibr35-j.wem.2020.04.009","doi-asserted-by":"publisher","DOI":"10.1080\/15563650.2019.1648817"}],"container-title":["Wilderness &amp; Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1080603220301010?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1080603220301010?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.wem.2020.04.009","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1016\/j.wem.2020.04.009","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.wem.2020.04.009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T03:06:11Z","timestamp":1741662371000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1016\/j.wem.2020.04.009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1016\/j.wem.2020.04.009"],"URL":"https:\/\/doi.org\/10.1016\/j.wem.2020.04.009","relation":{},"ISSN":["1080-6032","1545-1534"],"issn-type":[{"value":"1080-6032","type":"print"},{"value":"1545-1534","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9]]}}}