{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T18:57:00Z","timestamp":1785869820227,"version":"3.56.0"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,22]],"date-time":"2017-01-22T00:00:00Z","timestamp":1485043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World j. otorhinolaryngol.-head neck surg."],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The clinical presentation of sphenoid sinusitis can be highly variable. Rarely, sphenoid sinusitis may present with cranial nerve complications due to the proximity of these structures to the sphenoid sinus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A case series from Rabin Medical Center and all cases of cranial nerves palsies secondary to sphenoid sinusitis that have been reported in the literature were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventeen patients were identified. The abducent nerve was the most common cranial nerve affected (76%), followed by the oculomotor nerve (18%). One patient had combined oculomotor, trochlear and abducent palsies. The most common pathology was isolated purulent sphenoid sinusitis in 64% followed by allergic fungal sinusitis (AFS) in 18%, and fungal infection in 18%. 94% had an acute presentation. The majority (85%) received a combined intravenous antibiotics and surgical treatment. The remainder received conservative treatment alone. Complete recovery of cranial nerve palsy was noted in 82% during follow up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Sphenoid sinusitis presenting as diplopia and headaches is rare. A neoplastic process must be ruled out and early surgical intervention with intravenous antimicrobial therapy carry an excellent outcome with complete resolution of symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.wjorl.2017.02.001","type":"journal-article","created":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T06:49:26Z","timestamp":1488869366000},"page":"49-53","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Ocular cranial nerve palsies secondary to sphenoid sinusitis"],"prefix":"10.1002","volume":"3","author":[{"given":"Aiman","family":"El Mograbi","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Rabin Medical Center Petah Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ethan","family":"Soudry","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Rabin Medical Center Petah Tikva Israel"},{"name":"Sackler School of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940211100407"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198311103091904"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.6.777"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199712000-00003"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2003.11.011"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1941.00660040251002"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(95)70186-9"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100138204"},{"key":"e_1_2_6_10_1","first-page":"132","article-title":"Isolated sphenoid sinusitis","volume":"35","author":"Turgut S.","year":"1997","journal-title":"Rhinology"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480701762466"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-015-0053-y"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000436936.24787.82"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2013.27.3943"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.20344\/amp.5229"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13760-014-0292-0"},{"key":"e_1_2_6_17_1","first-page":"689","article-title":"Endoscopic sinus surgery for solitary abducens palsy in patients with isolated sphenoid sinus disease: report of four cases","volume":"25","author":"Lee L.A.","year":"2002","journal-title":"Chang Gung Med J"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459989110400604"}],"container-title":["World Journal of Otorhinolaryngology - 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