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However, when open resection is required, free flap reconstruction is often necessary to provide sufficient well\u2010vascularized tissue for optimal wound healing as well as providing adequate tissue bulk for cosmesis. This articleaims to providea focused review of free flaps most commonly used in anterior skull base reconstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a state\u2010of\u2010the\u2010art review based on expert opinion and previously published reviews and journal articles, queried using PubMed and Google Scholar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results &amp; conclusion<\/jats:title><jats:p>Anterior skull base reconstruction via free tissue transfer is imperative in limiting complications and promoting healing, particularly with large defects, post\u2010radiation, and in at\u2010risk patients. The type of free flap utilized for a particular anterior skull base reconstruction should be tailored to the patient and nature of the disease. This review offers insight into the numerous reconstructive options for the free flap surgeon.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.wjorl.2020.01.004","type":"journal-article","created":{"date-parts":[[2020,4,17]],"date-time":"2020-04-17T21:49:51Z","timestamp":1587160191000},"page":"132-136","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Free tissue reconstruction of the anterior skull base: A review"],"prefix":"10.1002","volume":"6","author":[{"given":"Elizabeth Bradford","family":"Bell","sequence":"first","affiliation":[{"name":"Department of Otolaryngology University of Miami Miller School of Medicine Miami FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin R.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Miami Miller School of Medicine Miami FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoukaa","family":"Sargi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Miami Miller School of Medicine Miami FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Leibowitz","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Miami Miller School of Medicine Miami FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3171\/2012.5.FOCUS12129"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240101500410"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24182"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e328325a525"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1301402"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000223"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.332.7543.710"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1607274"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-959333"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000234933.37779.e4"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2005.02.001"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200105000-00003"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1098966"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e32833a4706"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-200110000-00004"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200210000-00032"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otot.2012.10.006"},{"key":"e_1_2_5_19_1","unstructured":"B.Nussenbaum P.Pipkorn.Rectus abdominis flap for head and neck reconstruction. 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