{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:22:46Z","timestamp":1778685766869,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T00:00:00Z","timestamp":1588809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World j. otorhinolaryngol.-head neck surg."],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Multiple treatments are described in the literature for the treatment of chronic Eustachian tube dysfunction but high\u2010level quality evidence seems missing to support these treatments. This systematic review aimed to determine and compare the safety and efficacy of Laser Eustachian tuboplasty and Microdebrider Eustachian tuboplasty as a treatment for long\u2010term Eustachian tube dysfunction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data sources<\/jats:title><jats:p>A total of 12 electronic databases were searched up to April 2018 for published and unpublished literature in the English language. References of included studies were checked.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic review was undertaken. Outcomes assessed were: primary outcomes\u2010subjective improvement in symptoms (ETDQ\u20107), audiometric improvement of hearing, improvement of negative middle ear pressure noticed in tympanometry, objective improvement of tympanic membrane retraction. Secondary outcomes were\u2010the ability to auto\u2010insufflate Eustachian tube i.e. Valsalva manoeuvre, improved quality of life, passive tubal opening, tubomanometry, swallowing test, reduction in mucosal inflammation of Eustachian tube orifice in the nose, complications from the procedure, the need for further procedures. Results are reported in a narrative synthesis as a meta\u2010analysis was not possible due to heterogeneous data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three studies were included. All included studies were small\u2010scale case series (13\u201338 participants). Studies were conducted outside the UK. Subjective and objective improvement of Eustachian tube function was reported in all studies. But all included studies were at high risk of bias and subject to multiple limitations. No major complications were reported in either study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Based on current evidence, it is not possible to recommend the clinical use of either of these two interventions i.e. Laser or Microdebrider Eustachian tuboplasty. Lack of controlled studies was identified as a gap in the evidence. Future research should be directed toward designing randomised controlled trials. These trials should use strict standard methodology and reporting criteria. Future trials should make use of consensus statement document about Eustachian tube dysfunction definition, diagnostic methods, and outcome assessment criteria to design clinical trials.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.wjorl.2020.04.004","type":"journal-article","created":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T04:45:22Z","timestamp":1591850722000},"page":"54-62","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Laser vs microdebrider eustachian tuboplasty for the treatment of chronic adult eustachian tube dysfunction: A systematic review"],"prefix":"10.1002","volume":"7","author":[{"given":"Waqas","family":"Jamil","sequence":"first","affiliation":[{"name":"ENT Department Birmingham Heartland Hospital UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve","family":"Izzat","sequence":"additional","affiliation":[{"name":"Wrightington Wigan and Leigh NHS Foundation Trust UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1992.tb01004.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-004-1152-7"},{"key":"e_1_2_9_4_1","first-page":"1017","article-title":"The patulous eustachian tube\u2010novel surgical approaches","volume":"61","author":"Schr\u00f6der S.","year":"2013","journal-title":"HNO"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta18460"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12220"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599817753609"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599814567105"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215116008252"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26800"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-017-4476-0"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26827"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215117000974"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.10.031"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000246227.65877.1f"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-009-0646-7"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181de24bc"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000312871"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0346-9"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/0301-4738.71673"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1590\/2176-9451.19.4.027-029.ebo"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-1208.165154"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.332.7547.969"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0193841X16665199"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1298595"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-017-4476-0"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/31.1.115"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0266462312000086"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940211100907"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200401000-00001"},{"key":"e_1_2_9_31_1","first-page":"45","article-title":"Experiences with Nd:YAG laser interference for correction of Eustachian tube","volume":"25","author":"Boboshko M.Y.","year":"2005","journal-title":"Rivista Italiana di Otorinolaringologia Audiologia e Foniatria"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.12.046"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0b013e3181e85614"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e318248edcb"},{"key":"e_1_2_9_35_1","first-page":"299","article-title":"Restoring middle ear pressure equalization in divers by laser Eustachian tuboplasty","volume":"40","author":"Jumah M.J.","year":"2013","journal-title":"Undersea Hyperb Med"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12475"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.316.7126.201"},{"key":"e_1_2_9_38_1","first-page":"1341","article-title":"Randomized controlled trials \u2010 a matter of design","volume":"12","author":"Spieth P.M.","year":"2016","journal-title":"Neuropsychiatr Dis Treat"}],"container-title":["World Journal of Otorhinolaryngology - 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