{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:51:05Z","timestamp":1790085065911,"version":"4.0.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"name":"Covidien, Inc."}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1016\/j.wneu.2011.12.011","type":"journal-article","created":{"date-parts":[[2011,12,11]],"date-time":"2011-12-11T03:14:48Z","timestamp":1323573288000},"page":"498-504","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":77,"title":["A Multicenter, Single-Blind, Prospective Randomized Trial to Evaluate the Safety of a Polyethylene Glycol Hydrogel (Duraseal Dural Sealant System) as a Dural Sealant in Cranial Surgery"],"prefix":"10.1016","volume":"78","author":[{"given":"Joshua W.","family":"Osbun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard G.","family":"Ellenbogen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall M.","family":"Chesnut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence S.","family":"Chin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"Connolly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Rees","family":"Cosgrove","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Johnny B.","family":"Delashaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.","family":"Golfinos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy D.W.","family":"Greenlee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Haines","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Jallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Paul","family":"Muizelaar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Nanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Shaffrey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitesh V.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"John M.","family":"Tew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry R.","family":"van Loveren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin E.","family":"Weinand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan A.","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James E.","family":"Wilberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2011.12.011_bib1","unstructured":"IMS Hospital Supply Index (HSI) Database, December 2010. Accessed July 15th, 2011."},{"key":"10.1016\/j.wneu.2011.12.011_bib2","doi-asserted-by":"crossref","first-page":"e4","DOI":"10.3171\/foc.2000.9.1.4","article-title":"Cerebrospinal fluid leaks following spinal or posterior fossa surgery: use of fat grafts for prevention and repair","volume":"9","author":"Black","year":"2000","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2011.12.011_bib3","first-page":"250","article-title":"Cerebrospinal fluid leaks following spinal surgery: use of fat grafts for prevention and repair","volume":"96","author":"Black","year":"2002","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2011.12.011_bib4","first-page":"146","article-title":"Use of a novel absorbable hydrogel for augmentation of dural repair: results of a preliminary clinical study","volume":"57","author":"Boogaarts","year":"2005","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2011.12.011_bib5","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1177\/019459989110400115","article-title":"Cerebrospinal fluid leaks and meningitis in acoustic neuroma surgery","volume":"104","author":"Bryce","year":"1991","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.wneu.2011.12.011_bib6","doi-asserted-by":"crossref","first-page":"52","DOI":"10.3171\/jns.2007.106.1.52","article-title":"Safety and efficacy of a novel polyethylene glycol hydrogel sealant for watertight dural repair","volume":"106","author":"Cosgrove","year":"2007","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2011.12.011_bib7","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1097\/00005537-199608000-00017","article-title":"Cerebrospinal fluid drainage in the management of CSF leak following acoustic neuroma surgery","volume":"106","author":"Fishman","year":"1996","journal-title":"Laryngoscope"},{"key":"10.1016\/j.wneu.2011.12.011_bib8","doi-asserted-by":"crossref","first-page":"821","DOI":"10.3171\/jns.2002.97.4.0821","article-title":"Surgical procedures for posterior fossa tumors in children: does craniotomy lead to fewer complications than craniectomy?","volume":"97","author":"Gnanalingham","year":"2002","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2011.12.011_bib9","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1080\/02688690310001627777","article-title":"MRI study of the natural history and risk factors for pseudomeningocoele formation following postfossa surgery in children","volume":"17","author":"Gnanalingham","year":"2003","journal-title":"Br J Neurosurg"},{"key":"10.1016\/j.wneu.2011.12.011_bib10","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.surneu.2005.03.041","article-title":"Costs of postoperative cerebrospinal fluid leakage: 1-year, retrospective analysis of 412 consecutive nontrauma cases","volume":"64","author":"Grotenhuis","year":"2005","journal-title":"Surg Neurol"},{"key":"10.1016\/j.wneu.2011.12.011_bib11","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.surneu.2005.07.059","article-title":"Nonsuture dural repair using polyglycolic acid mesh and fibrin glue: clinical application to spinal surgery","volume":"65","author":"Hida","year":"2006","journal-title":"Surg Neurol"},{"key":"10.1016\/j.wneu.2011.12.011_bib12","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1288\/00005537-199401000-00009","article-title":"Cerebrospinal fluid leak following acoustic neuroma removal","volume":"104","author":"Hoffman","year":"1994","journal-title":"Laryngoscope"},{"key":"10.1016\/j.wneu.2011.12.011_bib13","doi-asserted-by":"crossref","first-page":"155","DOI":"10.3171\/jns.1998.89.1.0155","article-title":"Use of ligamentum nuchae graft for dural closure in posterior fossa surgery","volume":"89","author":"Kosnik","year":"1998","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2011.12.011_bib14","first-page":"172","article-title":"Autologous fibrin glue in the prevention of cerebrospinal fluid leak following acoustic neuroma surgery","volume":"16","author":"Lebowitz","year":"1995","journal-title":"Am J Otol"},{"key":"10.1016\/j.wneu.2011.12.011_bib15","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1227\/01.NEU.0000108640.45371.1A","article-title":"Comparison of deep wound infection rates using a synthetic dural substitute (neuro-patch) or pericranium graft for dural closure: a clinical review of 1 year","volume":"54","author":"Malliti","year":"2004","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2011.12.011_bib16","doi-asserted-by":"crossref","first-page":"2861","DOI":"10.1097\/01.brs.0000148049.69541.ad","article-title":"Collagen matrix (DuraGen) in dural repair: analysis of a new modified technique","volume":"29","author":"Narotam","year":"2004","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.1016\/j.wneu.2011.12.011_bib17","doi-asserted-by":"crossref","first-page":"406","DOI":"10.3171\/jns.1995.82.3.0406","article-title":"A clinicopathological study of collagen sponge as a dural graft in neurosurgery","volume":"82","author":"Narotam","year":"1995","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2011.12.011_bib18","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s10143-006-0060-6","article-title":"Intraoperative management to prevent cerebrospinal fluid leakage after microvascular decompression: dural closure with a \u201cplugging muscle\u201d method","volume":"30","author":"Park","year":"2007","journal-title":"Neurosurg Rev"},{"key":"10.1016\/j.wneu.2011.12.011_bib19","first-page":"166","article-title":"The use of fibrin sealant in cerebrospinal fluid leakage","volume":"34","author":"Pomeranz","year":"1991","journal-title":"Neurochirurgia (Stuttg)"},{"key":"10.1016\/j.wneu.2011.12.011_bib20","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1227\/01.NEU.0000089481.87226.F7","article-title":"Toward optimal tissue sealants for neurosurgery: use of a novel hydrogel sealant in a canine durotomy repair model","volume":"53","author":"Preul","year":"2003","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2011.12.011_bib21","doi-asserted-by":"crossref","first-page":"642","DOI":"10.3171\/JNS-07\/09\/0642","article-title":"Application of a hydrogel sealant improves watertight closures of duraplasty onlay grafts in a canine craniotomy model","volume":"107","author":"Preul","year":"2007","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2011.12.011_bib22","first-page":"11","article-title":"Management of 1000 vestibular schwannomas (acoustic neuromas): surgical management and results with an emphasis on complications and how to avoid them","volume":"40","author":"Samii","year":"1997","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2011.12.011_bib23","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1097\/00006123-199902000-00048","article-title":"Evaluation of application techniques of fibrin sealant to prevent cerebrospinal fluid leakage: a new device for the application of aerosolized fibrin glue","volume":"44","author":"Sawamura","year":"1999","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2011.12.011_bib24","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1212\/01.wnl.0000265400.54810.13","article-title":"Anaphylactic reactions to fibrin sealant injection for spontaneous spinal CSF leaks","volume":"70","author":"Schievink","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2011.12.011_bib25","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1227\/00006123-199002000-00004","article-title":"Neurosurgical applications of fibrin glue: augmentation of dural closure in 134 patients","volume":"26","author":"Shaffrey","year":"1990","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2011.12.011_bib26","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3171\/JNS\/2008\/109\/8\/0215","article-title":"Efficacy and safety of a collagen matrix for cranial and spinal dural reconstruction using different fixation techniques","volume":"109","author":"Stendel","year":"2008","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2011.12.011_bib27","first-page":"ONS182","article-title":"Polyethylene glycol hydrogel dural sealant may reduce incisional cerebrospinal fluid leak after posterior fossa surgery","volume":"63","author":"Than","year":"2008","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2011.12.011_bib28","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1007\/BF02747190","article-title":"Duraplasty with freeze-dried cadaveric dura versus occipital pericranium for Chiari type I malformation: comparative study","volume":"139","author":"Vanaclocha","year":"1997","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2011.12.011_bib29","doi-asserted-by":"crossref","first-page":"428","DOI":"10.3171\/2009.6.JNS081540","article-title":"The safety and effectiveness of a dural sealant system for use with nonautologous duraplasty materials","volume":"112","author":"Weinstein","year":"2010","journal-title":"J Neurosurg"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875011014872?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875011014872?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T08:07:04Z","timestamp":1761811624000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875011014872"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["S1878875011014872"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2011.12.011","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2012,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Multicenter, Single-Blind, Prospective Randomized Trial to Evaluate the Safety of a Polyethylene Glycol Hydrogel (Duraseal Dural Sealant System) as a Dural Sealant in Cranial Surgery","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2011.12.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}