{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:03:03Z","timestamp":1778817783002,"version":"3.51.4"},"reference-count":42,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","worldneurosurgery.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.wneu.2015.07.011","type":"journal-article","created":{"date-parts":[[2015,7,13]],"date-time":"2015-07-13T19:02:15Z","timestamp":1436814135000},"page":"1681-1685","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Fusiform Aneurysms Are Associated with Aortic Root Dilatation in Patients with Subarachnoid Hemorrhage"],"prefix":"10.1016","volume":"84","author":[{"given":"Anil","family":"Can","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Volovici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruben","family":"Dammers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clemens M.F.","family":"Dirven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Calum A.","family":"MacRae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2641-6496","authenticated-orcid":false,"given":"Rose","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2015.07.011_bib1","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/S0735-1097(03)00922-7","article-title":"Is aortic dilatation an atherosclerosis-related process? Clinical, laboratory, and transesophageal echocardiographic correlates of thoracic aortic dimensions in the population with implications for thoracic aortic aneurysm formation","volume":"42","author":"Agmon","year":"2003","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.wneu.2015.07.011_bib2","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/jhg.2010.82","article-title":"Genome-wide association study to identify genetic variants present in Japanese patients harboring intracranial aneurysms","volume":"55","author":"Akiyama","year":"2010","journal-title":"J\u00a0Hum Genet"},{"key":"10.1016\/j.wneu.2015.07.011_bib3","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1136\/jnnp.57.10.1279","article-title":"Intracranial fusiform aneurysms in von Recklinghausen's disease: case report and literature review","volume":"57","author":"Benatar","year":"1994","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.wneu.2015.07.011_bib4","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.4065\/78.12.1491","article-title":"Intracranial aneurysms in patients with coarctation of the aorta: a prospective magnetic resonance angiographic study of 100 patients","volume":"78","author":"Connolly","year":"2003","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.wneu.2015.07.011_bib5","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1161\/CIRCULATIONAHA.110.949131","article-title":"What is new in dilatation of the ascending aorta? Review of current literature and practical advice for the cardiologist","volume":"123","author":"Cozijnsen","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.wneu.2015.07.011_bib6","doi-asserted-by":"crossref","first-page":"228","DOI":"10.3171\/jns.2003.99.2.0228","article-title":"Spontaneous fusiform middle cerebral artery aneurysms: characteristics and a proposed mechanism of formation","volume":"99","author":"Day","year":"2003","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2015.07.011_bib7","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1001\/archinte.1916.00080130010002","article-title":"A\u00a0formula to estimate the approximate surface area if height and weight be known","volume":"17","author":"Du Bois","year":"1916","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.wneu.2015.07.011_bib8","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ydbio.2012.02.035","article-title":"Neural crest progenitors and stem cells: from early development to adulthood","volume":"366","author":"Dupin","year":"2012","journal-title":"Dev Biol"},{"key":"10.1016\/j.wneu.2015.07.011_bib9","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1242\/dev.128.7.1059","article-title":"The cephalic neural crest provides pericytes and smooth muscle cells to all blood vessels of the face and forebrain","volume":"128","author":"Etchevers","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.wneu.2015.07.011_bib10","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1017\/S0317167100001700","article-title":"Non-atherosclerotic fusiform cerebral aneurysms","volume":"29","author":"Findlay","year":"2002","journal-title":"Can J Neurol Sci"},{"key":"10.1016\/j.wneu.2015.07.011_bib11","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/0090-3019(85)90211-3","article-title":"Coarctation of the descending aorta with aneurysm of the anterior communicating artery","volume":"23","author":"Fukuda","year":"1985","journal-title":"Surg Neurol"},{"key":"10.1016\/j.wneu.2015.07.011_bib12","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0039-6060(97)90018-0","article-title":"Flow-induced arterial enlargement is inhibited by suppression of nitric oxide synthase activity in\u00a0vivo","volume":"122","author":"Guzman","year":"1997","journal-title":"Surgery"},{"key":"10.1016\/j.wneu.2015.07.011_bib13","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1080\/01616412.1998.11740494","article-title":"Evidence for apoptosis in human intracranial aneurysms","volume":"20","author":"Hara","year":"1998","journal-title":"Neurol Res"},{"key":"10.1016\/j.wneu.2015.07.011_bib14","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1161\/01.STR.28.3.660","article-title":"Case-fatality rates and functional outcome after subarachnoid hemorrhage: a systematic review","volume":"28","author":"Hop","year":"1997","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2015.07.011_bib15","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/S0022-5223(19)33931-5","article-title":"The neural crest as a possible pathogenetic factor in coarctation of the aorta and bicuspid aortic valve","volume":"102","author":"Kappetein","year":"1991","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.wneu.2015.07.011_bib16","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s007010170072","article-title":"Genesis of cerebral aneurysms\u2013an update","volume":"143","author":"Krex","year":"2001","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2015.07.011_bib17","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/j.mod.2004.06.003","article-title":"The avian embryo as a model to study the development of the neural crest: a long and still ongoing story","volume":"121","author":"Le Douarin","year":"2004","journal-title":"Mech Dev"},{"key":"10.1016\/j.wneu.2015.07.011_bib18","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/00006123-199908000-00010","article-title":"Proposed classification of nonatherosclerotic cerebral fusiform and dissecting aneurysms","volume":"45","author":"Mizutani","year":"1999","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2015.07.011_bib19","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1161\/01.STR.31.4.896","article-title":"Clinicopathological study of intracranial fusiform and dolichoectatic aneurysms : insight on the mechanism of growth","volume":"31","author":"Nakatomi","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2015.07.011_bib20","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S1050-1738(99)80002-4","article-title":"Cell origins and tissue boundaries during outflow tract development","volume":"5","author":"Noden","year":"1995","journal-title":"Trends Cardiovasc Med"},{"key":"10.1016\/j.wneu.2015.07.011_bib21","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0733-8619(18)30162-2","article-title":"The neurologic complications of congenital heart disease","volume":"11","author":"Park","year":"1993","journal-title":"Neurol Clin"},{"key":"10.1016\/j.wneu.2015.07.011_bib22","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3340\/jkns.2008.44.3.116","article-title":"Intracranial fusiform aneurysms: it's pathogenesis, clinical characteristics and managements","volume":"44","author":"Park","year":"2008","journal-title":"J\u00a0Korean Neurosurg Soc"},{"key":"10.1016\/j.wneu.2015.07.011_bib23","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S1474-4422(11)70017-5","article-title":"Long-term outcomes of patients with aneurysmal subarachnoid haemorrhage","volume":"10","author":"Rinkel","year":"2011","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.wneu.2015.07.011_bib24","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1161\/01.STR.29.1.251","article-title":"Prevalence and risk of rupture of intracranial aneurysms: a systematic review","volume":"29","author":"Rinkel","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2015.07.011_bib25","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/ar.1092260312","article-title":"Impaired elastic matrix development in the great arteries after ablation of the cardiac neural crest","volume":"226","author":"Rosenquist","year":"1990","journal-title":"Anat Rec"},{"key":"10.1016\/j.wneu.2015.07.011_bib26","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1212\/01.WNL.0000115104.19787.8E","article-title":"Characteristics of intracranial aneurysms in patients with familial subarachnoid hemorrhage","volume":"62","author":"Ruigrok","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2015.07.011_bib27","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1097\/00006123-199610000-00006","article-title":"Intracranial aneurysms and cervicocephalic arterial dissections associated with congenital heart disease","volume":"39","author":"Schievink","year":"1996","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2015.07.011_bib28","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1212\/WNL.0b013e3181dc1acf","article-title":"Screening for intracranial aneurysms in patients with bicuspid aortic valve","volume":"74","author":"Schievink","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2015.07.011_bib29","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/0002-9149(60)90303-9","article-title":"Ruptured intracranial aneurysm associated with coarctation of the aorta; report of a patient treated by hypothermia and surgical repair of the coarctation","volume":"6","author":"Schwartz","year":"1960","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.wneu.2015.07.011_bib30","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s007010200039","article-title":"Fusiform aneurysm of the posterior cerebral artery: report of two cases","volume":"144","author":"Selviaridis","year":"2002","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2015.07.011_bib31","doi-asserted-by":"crossref","first-page":"342","DOI":"10.2176\/nmc.32.342","article-title":"Ruptured cerebral aneurysm associated with coarctation of the aorta\u2013report of two cases","volume":"32","author":"Serizawa","year":"1992","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"10.1016\/j.wneu.2015.07.011_bib32","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1146\/annurev.fluid.40.111406.102126","article-title":"Hemodynamics of cerebral aneurysms","volume":"41","author":"Sforza","year":"2009","journal-title":"Annu Rev Fluid Mech"},{"key":"10.1016\/j.wneu.2015.07.011_bib33","doi-asserted-by":"crossref","first-page":"e100569","DOI":"10.1371\/journal.pone.0100569","article-title":"Echocardiographic evidence of innate aortopathy in the human intracranial aneurysm","volume":"9","author":"Shin","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.wneu.2015.07.011_bib34","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1161\/hq0701.092118","article-title":"Blood flow decrease induces apoptosis of endothelial cells in previously dilated arteries resulting from chronic high blood flow","volume":"21","author":"Sho","year":"2001","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.wneu.2015.07.011_bib35","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1097\/00006123-199811000-00156","article-title":"Familial intracranial aneurysms: an autopsy study","volume":"43","author":"Stehbens","year":"1998","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2015.07.011_bib36","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1161\/HYPERTENSIONAHA.115.05156","article-title":"Determinants of aortic root dilatation and reference values among young adults over a 20-year period: Coronary Artery Risk Development in Young Adults Study","volume":"66","author":"Teixido-Tura","year":"2015","journal-title":"Hypertension"},{"key":"10.1016\/j.wneu.2015.07.011_bib37","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/jmri.24183","article-title":"Determinants and normal values of ascending aortic diameter by age, gender, and race\/ethnicity in the Multi-Ethnic Study of Atherosclerosis (MESA)","volume":"39","author":"Turkbey","year":"2014","journal-title":"J\u00a0Magn Reson Imaging"},{"key":"10.1016\/j.wneu.2015.07.011_bib38","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1161\/01.CIR.91.3.734","article-title":"Determinants of echocardiographic aortic root size. The Framingham Heart Study","volume":"91","author":"Vasan","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.wneu.2015.07.011_bib39","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/S1474-4422(11)70109-0","article-title":"Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis","volume":"10","author":"Vlak","year":"2011","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.wneu.2015.07.011_bib40","doi-asserted-by":"crossref","first-page":"624","DOI":"10.2176\/nmc.40.624","article-title":"Dissecting aneurysm of the anterior cerebral artery requiring surgical treatment\u2013case report","volume":"40","author":"Wakabayashi","year":"2000","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"10.1016\/j.wneu.2015.07.011_bib41","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/00125817-200205000-00003","article-title":"Prevalence of aortic root dilation in the Ehlers-Danlos syndrome","volume":"4","author":"Wenstrup","year":"2002","journal-title":"Genet Med"},{"key":"10.1016\/j.wneu.2015.07.011_bib42","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1038\/ng.563","article-title":"Genome-wide association study of intracranial aneurysm identifies three new risk loci","volume":"42","author":"Yasuno","year":"2010","journal-title":"Nat Genet"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875015008773?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875015008773?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T00:58:46Z","timestamp":1652835526000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875015008773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S1878875015008773"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2015.07.011","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fusiform Aneurysms Are Associated with Aortic Root Dilatation in Patients with Subarachnoid Hemorrhage","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2015.07.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}