{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:09:39Z","timestamp":1783775379937,"version":"3.55.0"},"reference-count":12,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","worldneurosurgery.org","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.wneu.2017.08.183","type":"journal-article","created":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T13:00:56Z","timestamp":1504616456000},"page":"992.e11-992.e14","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Cerebrospinal Fluid Leak Rhinorrhea after Systemic Erlotinib Chemotherapy for Metastatic Lung Cancer: A Familiar Problem from an Unfamiliar Culprit"],"prefix":"10.1016","volume":"108","author":[{"given":"Blake","family":"Priddy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas A.","family":"Hardesty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Beer-Furlan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley","family":"Otto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel M.","family":"Prevedello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2017.08.183_bib1","doi-asserted-by":"crossref","first-page":"E2","DOI":"10.3171\/2012.4.FOCUS1268","article-title":"Spontaneous and medically induced cerebrospinal fluid leakage in the setting of pituitary adenomas: review of the literature","volume":"32","author":"Lam","year":"2012","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2017.08.183_bib2","doi-asserted-by":"crossref","first-page":"104","DOI":"10.4103\/0974-1208.86096","article-title":"Bromocriptine or cabergoline-induced cerebrospinal fluid rhinorrhea: a life-threatening complication during management of prolactinoma","volume":"4","author":"Singh","year":"2011","journal-title":"J\u00a0Hum Reprod Sci"},{"key":"10.1016\/j.wneu.2017.08.183_bib3","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1046\/j.1365-2265.2000.00901.x","article-title":"CSF rhinorrhoea following treatment with dopamine agonists for massive invasive prolactinomas","volume":"52","author":"Leong","year":"2000","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.wneu.2017.08.183_bib4","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1590\/S0004-282X2001000200023","article-title":"Cerebrospinal fluid fistula as the presenting manifestation of pituitary adenoma: case report with a 4-year follow-up","volume":"59","author":"Hanel","year":"2001","journal-title":"Arq Neuropsiquiatr"},{"key":"10.1016\/j.wneu.2017.08.183_bib5","first-page":"1","article-title":"Dramatic radiographic response resulting in cerebrospinal fluid rhinorrhea associated with sunitinib therapy in recurrent atypical meningioma: case report","author":"Raheja","year":"2016","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2017.08.183_bib6","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.wneu.2017.01.001","article-title":"Delayed CSF rhinorrhea after gamma knife radiosurgery with or without preceding transsphenoidal resection for pituitary pathology","volume":"100","author":"Perry","year":"2017","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2017.08.183_bib7","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S1470-2045(03)01137-9","article-title":"Inhibitors of epidermal-growth-factor receptors: a review of clinical research with a focus on non-small-cell lung cancer","volume":"4","author":"Sridhar","year":"2003","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.wneu.2017.08.183_bib8","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1056\/NEJMoa050753","article-title":"Erlotinib in previously treated non\u2013small cell lung cancer","volume":"353","author":"Shepherd","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.wneu.2017.08.183_bib9","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1097\/MLG.0b013e3181820171","article-title":"Cerebrospinal fluid leakage after gamma knife radiosurgery for skull base metastasis from renal cell carcinoma: a case report","volume":"118","author":"Kim","year":"2008","journal-title":"Laryngoscope"},{"key":"10.1016\/j.wneu.2017.08.183_bib10","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.surneu.2009.06.005","article-title":"Is surgical intervention frequently required for medically managed macroprolactinomas? A study of spontaneous cerebrospinal fluid rhinorrhea","volume":"72","author":"de Lacy","year":"2009","journal-title":"Surg Neurol"},{"key":"10.1016\/j.wneu.2017.08.183_bib11","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s11102-010-0274-z","article-title":"Transnasal trans-sphenoidal endoscopic repair of CSF leak secondary to invasive pituitary tumours using a nasoseptal flap","volume":"14","author":"Thakur","year":"2011","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2017.08.183_bib12","first-page":"140020","article-title":"Delayed presentation of late-onset cerebrospinal fluid rhinorrhoea following dopamine agonist therapy for giant prolactinoma","volume":"2014","author":"Prague","year":"2014","journal-title":"Endocrinol Diabetes Metab Case Rep"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875017314936?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875017314936?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,27]],"date-time":"2018-08-27T23:20:47Z","timestamp":1535412047000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875017314936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":12,"alternative-id":["S1878875017314936"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2017.08.183","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cerebrospinal Fluid Leak Rhinorrhea after Systemic Erlotinib Chemotherapy for Metastatic Lung Cancer: A Familiar Problem from an Unfamiliar Culprit","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2017.08.183","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}