{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T14:38:05Z","timestamp":1794062285717,"version":"4.8.0"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.wneu.2018.11.117","type":"journal-article","created":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T17:15:15Z","timestamp":1542993315000},"page":"e186-e193","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Transsphenoidal Approaches for Microsurgical Resection of Pituitary Adenomas in Pediatric Patients"],"prefix":"10.1016","volume":"123","author":[{"given":"Abdullah M.","family":"Abunimer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussam","family":"Abou-Al-Shaar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed A.","family":"Azab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0422-7937","authenticated-orcid":false,"given":"Michael","family":"Karsy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4762-7113","authenticated-orcid":false,"given":"Jian","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Kestle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William T.","family":"Couldwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2018.11.117_bib1","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1159\/000413694","article-title":"Pituitary adenomas in childhood and adolescence","volume":"30","author":"Laws","year":"1987","journal-title":"Prog Exp Tumor Res"},{"key":"10.1016\/j.wneu.2018.11.117_bib2","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1227\/00006123-199110000-00004","article-title":"Pediatric pituitary tumors","volume":"29","author":"Haddad","year":"1991","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2018.11.117_bib3","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1080\/01616412.1998.11740540","article-title":"Pituitary tumors in adolescent patients","volume":"20","author":"Artese","year":"1998","journal-title":"Neurol Res"},{"key":"10.1016\/j.wneu.2018.11.117_bib4","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.jocn.2004.10.003","article-title":"Pediatric pituitary adenoma: a series of 42 patients","volume":"12","author":"Pandey","year":"2005","journal-title":"J\u00a0Clin Neurosci"},{"key":"10.1016\/j.wneu.2018.11.117_bib5","first-page":"209","article-title":"Pituitary adenomas in childhood and adolescence. Results of transsphenoidal surgery","volume":"80","author":"Partington","year":"1994","journal-title":"J\u00a0Neurosurg"},{"issue":"suppl","key":"10.1016\/j.wneu.2018.11.117_bib6","doi-asserted-by":"crossref","first-page":"S95","DOI":"10.1507\/endocrj.47.SupplMarch_S95","article-title":"Pediatric pituitary adenoma","volume":"47","author":"Tamura","year":"2000","journal-title":"Endocr J"},{"key":"10.1016\/j.wneu.2018.11.117_bib7","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.wneu.2017.05.148","article-title":"Assessment of cost drivers in transsphenoidal approaches for resection of pituitary tumors using the value-driven outcome database","volume":"105","author":"Karsy","year":"2017","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2018.11.117_bib8","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1530\/EJE-10-0519","article-title":"Pituitary adenomas in childhood, adolescence and young adulthood: presentation, management, endocrine and metabolic outcomes","volume":"163","author":"Steele","year":"2010","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.wneu.2018.11.117_bib9","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3171\/2009.7.PEDS09252","article-title":"The transsphenoidal resection of pediatric craniopharyngiomas: a case series","volume":"5","author":"Jane","year":"2010","journal-title":"J\u00a0Neurosurg Pediatr"},{"key":"10.1016\/j.wneu.2018.11.117_bib10","first-page":"163","article-title":"Pituitary adenomas in childhood and adolescence","volume":"49","author":"Richmond","year":"1978","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2018.11.117_bib11","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1227\/00006123-199402000-00001","article-title":"Transsphenoidal surgery for pituitary adenomas in children","volume":"34","author":"Dyer","year":"1994","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2018.11.117_bib12","first-page":"1135","article-title":"Pituitary adenomas in childhood and adolescence","volume":"79","author":"Kane","year":"1994","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2018.11.117_bib13","first-page":"2475","article-title":"Long term follow-up of transsphenoidal surgery for the treatment of Cushing's disease in childhood","volume":"80","author":"Leinung","year":"1995","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2018.11.117_bib14","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1227\/00006123-199502000-00004","article-title":"Pediatric pituitary adenomas","volume":"36","author":"Mindermann","year":"1995","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2018.11.117_bib15","doi-asserted-by":"crossref","first-page":"4385","DOI":"10.1210\/jcem.84.12.6240","article-title":"Pediatric pituitary adenomas","volume":"84","author":"Kunwar","year":"1999","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2018.11.117_bib16","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1227\/01.NEU.0000166580.94215.53","article-title":"Cushing's disease in children and adolescents: 20 years of experience in a single neurosurgical center","volume":"57","author":"Joshi","year":"2005","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2018.11.117_bib17","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s00381-006-0259-4","article-title":"Pituitary tumors in children: clinical analysis of 21 cases","volume":"23","author":"Mehrazin","year":"2007","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.wneu.2018.11.117_bib18","doi-asserted-by":"crossref","first-page":"77","DOI":"10.5858\/2008-132-77-PPA","article-title":"Pediatric pituitary adenomas","volume":"132","author":"Webb","year":"2008","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.wneu.2018.11.117_bib19","doi-asserted-by":"crossref","first-page":"501","DOI":"10.3171\/2011.2.PEDS10278","article-title":"Microscopic endonasal transsphenoidal pituitary adenomectomy in the pediatric population","volume":"7","author":"Tarapore","year":"2011","journal-title":"J\u00a0Neurosurg Pediatr"},{"key":"10.1016\/j.wneu.2018.11.117_bib20","doi-asserted-by":"crossref","first-page":"369","DOI":"10.4158\/EP10143.OR","article-title":"Cushing disease in children and adolescents: twenty years' experience in a tertiary care center in India","volume":"17","author":"Shah","year":"2011","journal-title":"Endocr Pract"},{"key":"10.1016\/j.wneu.2018.11.117_bib21","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1210\/jc.2012-3604","article-title":"Outcome of surgical treatment of 200 children with Cushing's disease","volume":"98","author":"Lonser","year":"2013","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2018.11.117_bib22","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1136\/archdischild-2015-308365","article-title":"Surgical outcomes of the endoscopic transsphenoidal route to pituitary tumours in paediatric patients >10 years of age: 5 years of experience at a single institute","volume":"100","author":"Zhan","year":"2015","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.wneu.2018.11.117_bib23","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1097\/SCS.0000000000001946","article-title":"Endonasal endoscopic transsphenoidal approach to lesions of the sellar region in pediatric patients","volume":"26","author":"Zhan","year":"2015","journal-title":"J\u00a0Craniofac Surg"},{"key":"10.1016\/j.wneu.2018.11.117_bib24","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1159\/000381862","article-title":"Transnasal transsphenoidal surgical method in pediatric pituitary adenomas","volume":"50","author":"Taskapilioglu","year":"2015","journal-title":"Pediatr Neurosurg"},{"key":"10.1016\/j.wneu.2018.11.117_bib25","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1007\/s00381-017-3538-3","article-title":"A\u00a0retrospective review of 34 cases of pediatric pituitary adenoma","volume":"33","author":"Zhang","year":"2017","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.wneu.2018.11.117_bib26","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1097\/SCS.0000000000003632","article-title":"Microscopic transnasal transsphenoidal surgery for pediatric pituitary adenomas","volume":"28","author":"Jiao","year":"2017","journal-title":"J\u00a0Craniofac Surg"},{"key":"10.1016\/j.wneu.2018.11.117_bib27","doi-asserted-by":"crossref","unstructured":"Barzaghi LR, Losa M, Capitanio JF, Albano L, Weber G, Mortini P. Pediatric pituitary adenomas: early and long-term surgical outcome in a series of 85 consecutive patients [e-pub ahead of print]. Neurosurgery. https:\/\/doi.org\/10.1093\/neuros\/nyy204. August 13, 2018.","DOI":"10.1093\/neuros\/nyy204"},{"key":"10.1016\/j.wneu.2018.11.117_bib28","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1055\/s-0038-1625984","article-title":"Pediatric pituitary adenoma: case series, review of the literature, and a skull base treatment paradigm","volume":"79","author":"Perry","year":"2018","journal-title":"J\u00a0Neurol Surg B Skull Base"},{"issue":"suppl 1","key":"10.1016\/j.wneu.2018.11.117_bib29","first-page":"355","article-title":"Surgical management of craniopharyngiomas--experience with a pediatric series","volume":"19","author":"Di Rocco","year":"2006","journal-title":"J\u00a0Pediatr Endocrinol Metab"},{"key":"10.1016\/j.wneu.2018.11.117_bib30","first-page":"237","article-title":"Surgical treatment of craniopharyngiomas: experience with 168 patients","volume":"90","author":"Fahlbusch","year":"1999","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2018.11.117_bib31","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1159\/000103306","article-title":"Craniopharyngiomas in children","volume":"43","author":"Ohmori","year":"2007","journal-title":"Pediatr Neurosurg"},{"key":"10.1016\/j.wneu.2018.11.117_bib32","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1515\/JPEM.2006.19.2.121","article-title":"Weight gain in craniopharyngioma--a model for hypothalamic obesity","volume":"19","author":"Ahmet","year":"2006","journal-title":"J\u00a0Pediatr Endocrinol Metab"},{"issue":"suppl 1","key":"10.1016\/j.wneu.2018.11.117_bib33","first-page":"329","article-title":"Radical resection for craniopharyngiomas in children: surgical technique and clinical results","volume":"19","author":"Dhellemmes","year":"2006","journal-title":"J\u00a0Pediatr Endocrinol Metab"},{"issue":"suppl 1","key":"10.1016\/j.wneu.2018.11.117_bib34","first-page":"431","article-title":"Endocrine and growth features in childhood craniopharyngioma: a mono-institutional study","volume":"19","author":"Di Battista","year":"2006","journal-title":"J\u00a0Pediatr Endocrinol Metab"},{"key":"10.1016\/j.wneu.2018.11.117_bib35","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1007\/s00701-010-0929-6","article-title":"Quality of postoperative course in children: endoscopic endonasal surgery versus sublabial microsurgery","volume":"153","author":"Massimi","year":"2011","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2018.11.117_bib36","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.ijporl.2011.06.004","article-title":"Endoscopic transsphenoidal approach versus microscopic approach in children","volume":"75","author":"Rigante","year":"2011","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.wneu.2018.11.117_bib37","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1001\/jama.1910.04330090046014","article-title":"Endonasal method of removal of hypophyseal tumorswith report of two successful cases","volume":"55","author":"Hirsch","year":"1910","journal-title":"JAMA"},{"key":"10.1016\/j.wneu.2018.11.117_bib38","first-page":"140","article-title":"A\u00a0direct transnasal approach to the sphenoid sinus. Technical note","volume":"66","author":"Griffith","year":"1987","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2018.11.117_bib39","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1002\/lary.20964","article-title":"Anatomical considerations for endoscopic endonasal skull base surgery in pediatric patients","volume":"120","author":"Tatreau","year":"2010","journal-title":"Laryngoscope"},{"key":"10.1016\/j.wneu.2018.11.117_bib40","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/j.ijporl.2003.07.012","article-title":"The development of sphenoid sinus in Asian children","volume":"67","author":"Tan","year":"2003","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.wneu.2018.11.117_bib41","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3171\/ped.2007.106.2.75","article-title":"Fully endoscopic expanded endonasal approach treating skull base lesions in pediatric patients","volume":"106","author":"Kassam","year":"2007","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2018.11.117_bib42","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1007\/s003810000350","article-title":"The role of the endoscopic transsphenoidal approach in pediatric neurosurgery","volume":"16","author":"de Divitiis","year":"2000","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.wneu.2018.11.117_bib43","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1055\/s-0037-1615806","article-title":"Skull base reconstruction in the pediatric patient","volume":"79","author":"Duek","year":"2018","journal-title":"J\u00a0Neurol Surg B Skull Base"},{"key":"10.1016\/j.wneu.2018.11.117_bib44","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1007\/s00381-008-0710-9","article-title":"Combined endoscopic and microscopic management of pediatric pituitary region tumors through one nostril: technical note with case illustrations","volume":"24","author":"Frazier","year":"2008","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.wneu.2018.11.117_bib45","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.ijporl.2010.08.009","article-title":"Endoscopic endonasal transsphenoidal surgery for sellar tumors in children","volume":"74","author":"Locatelli","year":"2010","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.wneu.2018.11.117_bib46","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3171\/2012.10.PEDS12160","article-title":"Endoscopic endonasal skull base surgery in the pediatric population","volume":"11","author":"Chivukula","year":"2013","journal-title":"J\u00a0Neurosurg Pediatr"},{"key":"10.1016\/j.wneu.2018.11.117_bib47","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1002\/lary.20216","article-title":"Endoscopic pedicled nasoseptal flap reconstruction for pediatric skull base defects","volume":"119","author":"Shah","year":"2009","journal-title":"Laryngoscope"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875018326676?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875018326676?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T20:27:53Z","timestamp":1662496073000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875018326676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":47,"alternative-id":["S1878875018326676"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2018.11.117","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transsphenoidal Approaches for Microsurgical Resection of Pituitary Adenomas in Pediatric Patients","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2018.11.117","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}