{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T05:40:22Z","timestamp":1784958022780,"version":"3.55.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.wneu.2019.03.132","type":"journal-article","created":{"date-parts":[[2019,3,21]],"date-time":"2019-03-21T14:27:09Z","timestamp":1553178429000},"page":"354-358","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Klippel-Trenaunay-Weber Syndrome with Atypical Presentation of Cerebral Cavernous Angioma: A Case Report and Literature Review"],"prefix":"10.1016","volume":"126","author":[{"given":"Ali","family":"Karadag","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Senoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sevil","family":"Sayhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lela","family":"Okromelidze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik H.","family":"Middlebrooks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2019.03.132_bib1","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.wneu.2017.10.040","article-title":"Spinal cavernous angioma associated with Klippel-Trenaunay-Weber syndrome: Case report and literature review","volume":"109","author":"Oda","year":"2018","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2019.03.132_bib2","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.jvsv.2016.10.084","article-title":"Diagnosis and management of the venous malformations of Klippel-Trenaunay syndrome","volume":"5","author":"Wang","year":"2017","journal-title":"J\u00a0Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.wneu.2019.03.132_bib3","doi-asserted-by":"crossref","first-page":"552","DOI":"10.5999\/aps.2015.42.5.552","article-title":"Clinical experience of the Klippel-Trenaunay syndrome","volume":"42","author":"Sung","year":"2015","journal-title":"Arch Plast Surg"},{"key":"10.1016\/j.wneu.2019.03.132_bib4","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1258\/026835507782655209","article-title":"Klippel-Trenaunay syndrome: Current management","volume":"22","author":"Gloviczki","year":"2007","journal-title":"Phlebology"},{"key":"10.1016\/j.wneu.2019.03.132_bib5","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s12891-018-2393-z","article-title":"Kyphoscoliosis with Klippel-Trenaunay syndrome: A case report and literature review","volume":"20","author":"Zhai","year":"2019","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.wneu.2019.03.132_bib6","first-page":"140","article-title":"Action tremor caused by olivary cavernoma in Klippel-Tr\u00e9naunay syndrome mimicking asymmetric essential tremor","volume":"258","author":"S\u00fcdmeyer","year":"2011","journal-title":"J\u00a0Neurol"},{"key":"10.1016\/j.wneu.2019.03.132_bib7","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1007\/s11596-018-1964-4","article-title":"Radiological aspect of Klippel-Trenaunay syndrome: A case series with review of literature","volume":"38","author":"Alwalid","year":"2018","journal-title":"Curr Med Sci"},{"key":"10.1016\/j.wneu.2019.03.132_bib8","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2014-207486","article-title":"Klippel-Trenaunay syndrome and cavernous malformations","volume":"2014","author":"Ricks","year":"2014","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.wneu.2019.03.132_bib9","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.jocn.2009.11.013","article-title":"Multiple cerebral and spinal cord cavernomas in Klippel-Trenaunay-Weber syndrome","volume":"17","author":"Boutarbouch","year":"2010","journal-title":"J\u00a0Clin Neurosci"},{"key":"10.1016\/j.wneu.2019.03.132_bib10","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s00701-017-3408-5","article-title":"Cerebral and spinal cavernomas associated with Klippel-Trenaunay syndrome: Case report and literature review","volume":"160","author":"Yoshinaga","year":"2018","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2019.03.132_bib11","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/bjs.1800720331","article-title":"The Klippel-Trenaunay syndrome: Clinical, radiological and haemodynamic features and management","volume":"72","author":"Baskerville","year":"1985","journal-title":"Br J Surg"},{"key":"10.1016\/j.wneu.2019.03.132_bib12","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1097\/00000658-198511000-00015","article-title":"The etiology of the Klippel-Trenaunay syndrome","volume":"202","author":"Baskerville","year":"1985","journal-title":"Ann Surg"},{"key":"10.1016\/j.wneu.2019.03.132_bib13","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3109\/2000656X.2013.766201","article-title":"Diverse manifestations and management options in Klippel-Trenaunay syndrome: A single centre 10-year experience","volume":"47","author":"Sreekar","year":"2013","journal-title":"J\u00a0Plast Surg Hand Surg"},{"key":"10.1016\/j.wneu.2019.03.132_bib14","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0025-6196(11)63615-X","article-title":"Klippel-Trenaunay syndrome: Spectrum and management","volume":"73","author":"Jacob","year":"1998","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.wneu.2019.03.132_bib15","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1007\/s002340000310","article-title":"Klippel-Trenaunay syndrome: Frequency of cerebral and cerebellar hemihypertrophy on MRI","volume":"42","author":"Torregrosa","year":"2000","journal-title":"Neuroradiology"},{"key":"10.1016\/j.wneu.2019.03.132_bib16","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1001\/jamaneurol.2013.587","article-title":"Neurologic and vascular abnormalities in Klippel-Trenaunay-Weber syndrome","volume":"70","author":"Renard","year":"2013","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.wneu.2019.03.132_bib17","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/0720-048X(94)90340-9","article-title":"The use of ultrasound in the venous assessment of lower limb Klippel-Trenaunay syndrome","volume":"18","author":"Howlett","year":"1994","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.wneu.2019.03.132_bib18","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1111\/j.1365-2133.1992.tb00107.x","article-title":"Genetic aspects of the Klippel-Trenaunay syndrome","volume":"126","author":"Aelvoet","year":"1992","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.wneu.2019.03.132_bib19","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1002\/(SICI)1096-8628(19960614)63:3<426::AID-AJMG2>3.0.CO;2-P","article-title":"A\u00a0new case of Klippel-Trenaunay-Weber (KTW) syndrome: Evidence of autosomal dominant inheritance","volume":"63","author":"Ceballos-Quintal","year":"1996","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.wneu.2019.03.132_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpeds.2014.12.069","article-title":"Lymphatic and other vascular malformative\/overgrowth disorders are caused by somatic mutations in PIK3CA","volume":"166","author":"Luks","year":"2015","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.wneu.2019.03.132_bib21","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.gde.2005.03.004","article-title":"RASA1: Variable phenotype with capillary and arteriovenous malformations","volume":"15","author":"Boon","year":"2005","journal-title":"Curr Opin Genet Dev"},{"key":"10.1016\/j.wneu.2019.03.132_bib22","doi-asserted-by":"crossref","first-page":"496","DOI":"10.5114\/ninp.2012.31362","article-title":"Multiple spinal cavernous malformations in Klippel-Trenaunay-Weber syndrome","volume":"46","author":"Goksu","year":"2012","journal-title":"Neurol Neurochir Pol"},{"key":"10.1016\/j.wneu.2019.03.132_bib23","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s00403-008-0842-5","article-title":"A\u00a0novel mutation in RASA1 causes capillary malformation and limb enlargement","volume":"300","author":"Hershkovitz","year":"2008","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.wneu.2019.03.132_bib24","doi-asserted-by":"crossref","first-page":"10677","DOI":"10.1073\/pnas.122354499","article-title":"KRIT1, a gene mutated in cerebral cavernous malformation, encodes a microtubule-associated protein","volume":"99","author":"Gunel","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.wneu.2019.03.132_bib25","first-page":"86","article-title":"Klippel-Trenaunay and Sturge-Weber overlapping syndrome in a Saudi boy","volume":"16","author":"Kentab","year":"2016","journal-title":"Sudan J Paediatr"},{"key":"10.1016\/j.wneu.2019.03.132_bib26","first-page":"595476","article-title":"Sonographic identification of Klippel-Trenaunay-Weber syndrome","volume":"2013","author":"Cakiroglu","year":"2013","journal-title":"Case Rep Obstet Gynecol"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875019308101?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875019308101?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T08:30:26Z","timestamp":1761813026000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875019308101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":26,"alternative-id":["S1878875019308101"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2019.03.132","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Klippel-Trenaunay-Weber Syndrome with Atypical Presentation of Cerebral Cavernous Angioma: A Case Report and Literature Review","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2019.03.132","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}