{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T17:03:09Z","timestamp":1777482189464,"version":"3.51.4"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.wneu.2019.08.119","type":"journal-article","created":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T19:44:24Z","timestamp":1567712664000},"page":"e443-e446","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Effect of L-Arginine Therapy on Vasospasm: Experimental Study in Rats"],"prefix":"10.1016","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8582-2948","authenticated-orcid":false,"given":"Ezgi","family":"Akar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selin Tural","family":"Emon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serap","family":"Uslu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Metin","family":"Orakdogen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan","family":"Somay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2019.08.119_bib1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1161\/01.STR.20.2.217","article-title":"Prostaglandins and vasoactive amines in cerebral vasospasm after aneurysmal subarachnoid hemorrhage","volume":"20","author":"Chehrazi","year":"1989","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2019.08.119_bib2","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.nec.2014.04.008","article-title":"Cerebral vasospasm","volume":"25","author":"Baggott","year":"2014","journal-title":"Neurosurg Clin N Am"},{"key":"10.1016\/j.wneu.2019.08.119_bib3","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1161\/CIRCULATIONAHA.105.602532","article-title":"Endothelial nitric oxide synthase in vascular disease","volume":"13","author":"F\u00f6rstermann","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.wneu.2019.08.119_bib4","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/0092-8674(94)90266-6","article-title":"Nitric oxide synthase: roles, tolls, and controls","volume":"78","author":"Nathan","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.wneu.2019.08.119_bib5","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1227\/00006123-199009000-00002","article-title":"A\u00a0rat femoral artery model for vasospasm","volume":"27","author":"Okada","year":"1990","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2019.08.119_bib6","series-title":"Temel N\u00f6ro\u015firurji","first-page":"191","author":"K\u0131l\u0131\u00e7","year":"2005"},{"key":"10.1016\/j.wneu.2019.08.119_bib7","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jocn.2006.10.010","article-title":"Antiinflammatory effect of meloxicam on experimental vasospasm in the rat femoral artery","volume":"15","author":"Hakan","year":"2008","journal-title":"J\u00a0Clin Neurosci"},{"key":"10.1016\/j.wneu.2019.08.119_bib8","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/978-3-211-75718-5_7","article-title":"Oxidative stress in subarachnoid haemorrhage: significance in acute brain injury and vasospasm","volume":"104","author":"Ayer","year":"2008","journal-title":"Acta Neurochirurg"},{"key":"10.1016\/j.wneu.2019.08.119_bib9","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1179\/174313209X393906","article-title":"Glutathione peroxidase and subarachnoid hemorrhage: implications for the role of oxidative stress in cerebral vasospasm","volume":"31","author":"Pyne-Geithman","year":"2009","journal-title":"Neurol Res"},{"key":"10.1016\/j.wneu.2019.08.119_bib10","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1097\/00006123-200002000-00035","article-title":"In\u00a0vivo animal models of cerebral vasospasm: a review","volume":"46","author":"Megyesi","year":"2000","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2019.08.119_bib11","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.surneu.2007.07.031","article-title":"The effects of resveratrol on vasospasm after experimental subarachnoidal hemorrhage in rats","volume":"70","author":"Karaoglan","year":"2008","journal-title":"Surg Neurol"},{"key":"10.1016\/j.wneu.2019.08.119_bib12","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1227\/01.NEU.0000338067.83059.EB","article-title":"Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage","volume":"64","author":"Munakata","year":"2009","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2019.08.119_bib13","series-title":"Cerebral Blood Flow and Metabolism","author":"Edvinsson","year":"2002"},{"key":"10.1016\/j.wneu.2019.08.119_bib14","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.pharmthera.2004.10.002","article-title":"Delayed cerebral vasospasm and nitric oxide: review, new hypothesis, and proposed treatment","volume":"105","author":"Pluta","year":"2005","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.wneu.2019.08.119_bib15","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1227\/01.NEU.0000210182.48546.8F","article-title":"Intracranial delivery of the nitric oxide donor diethylenetriamine\/nitric oxide from a controlled-release polymeter: toxicity in cynomolgus monkeys","volume":"58","author":"Tierney","year":"2006","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2019.08.119_bib16","first-page":"279","article-title":"Reversal of cerebral vasospasm using an intrathecally administered nitric oxide donor","volume":"89","author":"Wolf","year":"1998","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2019.08.119_bib17","first-page":"862","article-title":"Hemin activation of an inducible isoform of nitric oxide synthase in vascular smooth-muscle cells","volume":"83","author":"Suzuki","year":"1995","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2019.08.119_bib18","first-page":"476","article-title":"Combined effect of L-arginine and superoxide dismutase on the spastic basilar artery after subarachnoid hemorrhage in dogs","volume":"80","author":"Kajita","year":"1994","journal-title":"J\u00a0Neurosurg"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875019322752?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875019322752?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T08:33:03Z","timestamp":1761813183000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875019322752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":18,"alternative-id":["S1878875019322752"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2019.08.119","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of L-Arginine Therapy on Vasospasm: Experimental Study in Rats","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2019.08.119","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}