{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:31:57Z","timestamp":1762018317969,"version":"build-2065373602"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.wneu.2020.10.065","type":"journal-article","created":{"date-parts":[[2020,10,17]],"date-time":"2020-10-17T19:38:18Z","timestamp":1602963498000},"page":"6-13","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Hypothalamic Cavernomas: Pediatric Case Report with 8.5-Year Follow-up and Review of the Literature"],"prefix":"10.1016","volume":"146","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7760-1491","authenticated-orcid":false,"given":"Gennadiy A.","family":"Katsevman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bayan","family":"Razzaq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesar A.","family":"Serrano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2020.10.065_bib1","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/nrneurol.2009.177","article-title":"Cavernous malformations: natural history, diagnosis and treatment","volume":"5","author":"Batra","year":"2009","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.wneu.2020.10.065_bib2","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1046\/j.1440-1673.2001.00914.x","article-title":"Cavernous haemangiomas (angiomas) of the brain","volume":"45","author":"Sage","year":"2001","journal-title":"Australas Radiol"},{"key":"10.1016\/j.wneu.2020.10.065_bib3","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.surneu.2004.05.032","article-title":"Intracranial cavernous angioma: a practical review of clinical and biological aspects","volume":"63","author":"Raychaudhuri","year":"2005","journal-title":"Surg Neurol"},{"key":"10.1016\/j.wneu.2020.10.065_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2010.5.FOCUS10149","article-title":"Update on the natural history of cavernous malformations and factors predicting aggressive clinical presentation","volume":"29","author":"Washington","year":"2010","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2020.10.065_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2011.3.FOCUS1165","article-title":"The natural history of intracranial cavernous malformations","volume":"30","author":"Gross","year":"2011","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2020.10.065_bib6","first-page":"197","article-title":"Intracranial and orbital cavernous angiomas. A review of 30 cases","volume":"64","author":"Yamasaki","year":"1986","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib7","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1227\/00006123-198602000-00008","article-title":"Cavernous angioma: a review of 126 collected and 12 new clinical cases","volume":"18","author":"Simard","year":"1986","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2020.10.065_bib8","first-page":"518","article-title":"The MRI appearance of cavernous malformations (angiomas)","volume":"67","author":"Rigamonti","year":"1987","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2010.5.FOCUS10129","article-title":"Cavernous malformations of the optic pathway and hypothalamus: analysis of 65 cases in the literature","volume":"29","author":"Liu","year":"2010","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2020.10.065_bib10","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1148\/rg.322105761","article-title":"Intracranial lesions with high signal intensity on T1-weighted MR images: differential diagnosis","volume":"32","author":"Ginat","year":"2012","journal-title":"RadioGraphics"},{"key":"10.1016\/j.wneu.2020.10.065_bib11","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s10140-011-0940-0","article-title":"Exophytic hypothalamic cavernous malformation mimicking an extra-axial suprasellar mass","volume":"18","author":"Rheinboldt","year":"2011","journal-title":"Emerg Radiol"},{"key":"10.1016\/j.wneu.2020.10.065_bib12","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s00234-017-1867-2","article-title":"Sensitivity of susceptibility-weighted imaging in detecting developmental venous anomalies and associated cavernomas and microhemorrhages in children","volume":"59","author":"Young","year":"2017","journal-title":"Neuroradiology"},{"key":"10.1016\/j.wneu.2020.10.065_bib13","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1093\/neuros\/nyx091","article-title":"Synopsis of guidelines for the clinical management of cerebral cavernous malformations: consensus recommendations based on systematic literature review by the angioma alliance scientific advisory board clinical experts panel","volume":"80","author":"Akers","year":"2017","journal-title":"Clin Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib14","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3171\/2011.11.PEDS11390","article-title":"Natural history and imaging prevalence of cavernous malformations in children and young adults. Clinical article","volume":"9","author":"Al-Holou","year":"2012","journal-title":"J\u00a0Neurosurg Pediatr"},{"key":"10.1016\/j.wneu.2020.10.065_bib15","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/PL00014581","article-title":"Central nervous system cavernomas in the pediatric age group","volume":"24","author":"Mottolese","year":"2001","journal-title":"Neurosurg Rev"},{"key":"10.1016\/j.wneu.2020.10.065_bib16","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1159\/000209283","article-title":"Cavernous malformations of the central nervous system in the pediatric age group","volume":"45","author":"Acciarri","year":"2009","journal-title":"Pediatr Neurosurg"},{"issue":"5 suppl","key":"10.1016\/j.wneu.2020.10.065_bib17","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3171\/ped.2007.106.5.379","article-title":"Incidence of cavernoma development in children after radiotherapy for brain tumors","volume":"106","author":"Burn","year":"2007","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib18","first-page":"1158","article-title":"Radiation-induced cavernomas of the brain","volume":"26","author":"Jain","year":"2005","journal-title":"Am J Neuroradiol"},{"key":"10.1016\/j.wneu.2020.10.065_bib19","doi-asserted-by":"crossref","first-page":"E805","DOI":"10.1227\/01.NEU.0000343668.44288.18","article-title":"Brainstem cavernous malformations","volume":"64","author":"Gross","year":"2009","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2020.10.065_bib20","first-page":"422","article-title":"The natural history of familial cavernous malformations: results of an ongoing study","volume":"80","author":"Zabramski","year":"1994","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib21","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1001\/archneur.1981.00510060081017","article-title":"Cavernous hemangioma in the diencephalon","volume":"38","author":"Mizutani","year":"1981","journal-title":"Arch Neurol"},{"key":"10.1016\/j.wneu.2020.10.065_bib22","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1620\/tjem.166.259","article-title":"Clinical analysis of ten cases with surgically treated brain stem cavernous angiomas","volume":"166","author":"Mizoi","year":"1992","journal-title":"Tohoku J Exp Med"},{"key":"10.1016\/j.wneu.2020.10.065_bib23","doi-asserted-by":"crossref","first-page":"238","DOI":"10.2176\/nmc.35.238","article-title":"Mixed cavernous angioma and glioma (angioglioma) in the hypothalamus\u2014case report","volume":"35","author":"Hasegawa","year":"1995","journal-title":"Neurol Med Chir (Tokyo)"},{"issue":"suppl 1","key":"10.1016\/j.wneu.2020.10.065_bib24","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1054\/jocn.2001.0888","article-title":"Surgical strategy for cavernous angioma in hypothalamus","volume":"8","author":"Kurokawa","year":"2001","journal-title":"J\u00a0Clin Neurosci"},{"key":"10.1016\/j.wneu.2020.10.065_bib25","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s00701-003-0041-2","article-title":"Multiple deep-seated cavernomas in the third ventricle, hypothalamus and thalamus","volume":"145","author":"Wang","year":"2003","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2020.10.065_bib26","first-page":"234","article-title":"Cavernoma of the hypothalamus","volume":"14","author":"Toe","year":"2011","journal-title":"Hong Kong J Radiol"},{"key":"10.1016\/j.wneu.2020.10.065_bib27","first-page":"246","article-title":"Hypothalamic cavernous angioma associated with memory and behavior disturbance attacks: Role of imaging in diagnosis","volume":"9","author":"Patil","year":"2012","journal-title":"Iran J Radiol"},{"key":"10.1016\/j.wneu.2020.10.065_bib28","doi-asserted-by":"crossref","first-page":"339","DOI":"10.4103\/jnrp.jnrp_282_18","article-title":"Blooming in the hypothalamus","volume":"10","author":"Rai","year":"2019","journal-title":"J\u00a0Neurosci Rural Pract"},{"key":"10.1016\/j.wneu.2020.10.065_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s101430100179","article-title":"Cerebral cavernomas in the adult. Review of the literature and analysis of 72 surgically treated patients","volume":"25","author":"Bertalanffy","year":"2002","journal-title":"Neurosurg Rev"},{"key":"10.1016\/j.wneu.2020.10.065_bib30","doi-asserted-by":"crossref","first-page":"105830","DOI":"10.1016\/j.clineuro.2020.105830","article-title":"Cerebral cavernous malformation presenting in childhood: a single-centered surgical experience of 29 cases","volume":"194","author":"Aslan","year":"2020","journal-title":"Clin Neurol Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib31","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1159\/000209284","article-title":"Pediatric cavernous malformation in the central nervous system: report of 66 cases","volume":"45","author":"Xia","year":"2009","journal-title":"Pediatr Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib32","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3171\/2015.2.PEDS14541","article-title":"The natural history of cerebral cavernous malformations in children","volume":"17","author":"Gross","year":"2016","journal-title":"J\u00a0Neurosurg Pediatr"},{"key":"10.1016\/j.wneu.2020.10.065_bib33","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1007\/s00381-017-3429-7","article-title":"Cavernous malformations of central nervous system in pediatric patients: our single-centered experience in 50 patients and review of literature","volume":"33","author":"Sawarkar","year":"2017","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.wneu.2020.10.065_bib34","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s00381-007-0465-8","article-title":"Management of intracranial cavernous malformation in pediatric patients","volume":"24","author":"Lee","year":"2008","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.wneu.2020.10.065_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2011.9.FOCUS11211","article-title":"Management of incidental cavernous malformations: a review","volume":"31","author":"Dalyai","year":"2011","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2020.10.065_bib36","doi-asserted-by":"crossref","first-page":"E15","DOI":"10.3171\/2017.6.FOCUS17256","article-title":"The hypothalamus at the crossroads of psychopathology and neurosurgery","volume":"43","author":"Barbosa","year":"2017","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2020.10.065_bib37","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.optm.2009.07.016","article-title":"Vision and the hypothalamus","volume":"81","author":"Trachtman","year":"2010","journal-title":"Optometry"},{"key":"10.1016\/j.wneu.2020.10.065_bib38","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1227\/01.NEU.0000073531.84342.C2","article-title":"Surgical management of cavernous malformations involving the cranial nerves","volume":"53","author":"Deshmukh","year":"2003","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2020.10.065_bib39","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s00701-006-0751-3","article-title":"Cavernous haemangiomas of the anterior visual pathways. Short review on occasion of an exceptional case","volume":"148","author":"Lehner","year":"2006","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2020.10.065_bib40","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1080\/02688690601000238","article-title":"Cavernous malformation of the optic chiasm: Case report","volume":"20","author":"Muta","year":"2006","journal-title":"Br J Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib41","first-page":"981","article-title":"Dynamic nature of cavernous malformations: a prospective magnetic resonance imaging study with volumetric analysis","volume":"93","author":"Clatterbuck","year":"2000","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib42","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.wneu.2015.11.003","article-title":"Propranolol treatment of cavernous malformations with symptomatic hemorrhage","volume":"88","author":"Zabramski","year":"2016","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib43","first-page":"31","article-title":"Deep and brainstem cavernomas: a consecutive 8-year series","volume":"99","author":"Mathiesen","year":"2003","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib44","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3171\/foc.2006.21.1.6","article-title":"The association of venous developmental anomalies and cavernous malformations: pathophysiological, diagnostic, and surgical considerations","volume":"21","author":"Perrini","year":"2006","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2020.10.065_bib45","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1227\/00006123-199410000-00026","article-title":"Endoscopic resection of a subthalamic cavernous angioma: technical case report","volume":"35","author":"Otsuki","year":"1994","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2020.10.065_bib46","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1227\/NEU.0000000000001033","article-title":"Magnetic resonance thermometry-guided stereotactic laser ablation of cavernous malformations in drug-resistant epilepsy: imaging and clinical results","volume":"12","author":"McCracken","year":"2016","journal-title":"Oper Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib47","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1007\/s00701-020-04316-7","article-title":"Stereotactic laser interstitial thermal therapy for brainstem cavernous malformations: two preliminary cases","volume":"162","author":"Gamboa","year":"2020","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2020.10.065_bib48","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/epi.14634","article-title":"Safety and effectiveness of stereotactic laser ablation for epileptogenic cerebral cavernous malformations","volume":"60","author":"Willie","year":"2019","journal-title":"Epilepsia"},{"key":"10.1016\/j.wneu.2020.10.065_bib49","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.nec.2015.08.007","article-title":"Stereotactic laser ablation for hypothalamic hamartoma","volume":"27","author":"Rolston","year":"2016","journal-title":"Neurosurg Clin N Am"},{"key":"10.1016\/j.wneu.2020.10.065_bib50","doi-asserted-by":"crossref","first-page":"E10","DOI":"10.3171\/2016.7.FOCUS16236","article-title":"Stereotactic laser ablation for hypothalamic and deep intraventricular lesions","volume":"41","author":"Buckley","year":"2016","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2020.10.065_bib51","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.wneu.2018.11.166","article-title":"Improvement of hypothalamic hamartoma-related psychiatric disorder after stereotactic laser ablation: case report and review of literature","volume":"122","author":"Arocho-Quinones","year":"2019","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib52","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1093\/neuros\/nyx604","article-title":"Magnetic resonance imaging-guided laser interstitial thermal therapy for the treatment of hypothalamic hamartomas: a retrospective review","volume":"83","author":"Xu","year":"2018","journal-title":"Clin Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib53","first-page":"1190","article-title":"Long-term results after stereotactic radiosurgery for patients with cavernous malformations","volume":"50","author":"Hasegawa","year":"2002","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2020.10.065_bib54","first-page":"164","article-title":"Erratum: Brainstem cavernous malformations: the role of Gamma Knife surgery","volume":"117","author":"Lee","year":"2012","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2010.7.FOCUS10151","article-title":"Stereotactic radiosurgery for the treatment of symptomatic brainstem cavernous malformations","volume":"29","author":"Monaco","year":"2010","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2020.10.065_bib56","first-page":"691","article-title":"Stereotactic radiosurgery for deep-seated cavernous malformations: a move toward more active, early intervention: clinical article","volume":"113","author":"Nagy","year":"2010","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2020.10.065_bib57","first-page":"16","article-title":"Radiosurgery in cavernous malformations: anatomy of a controversy","volume":"113","author":"Steiner","year":"2010","journal-title":"J\u00a0Neurosurg"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875020322579?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875020322579?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T08:57:54Z","timestamp":1761814674000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875020322579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":57,"alternative-id":["S1878875020322579"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2020.10.065","relation":{},"ISSN":["1878-8750"],"issn-type":[{"type":"print","value":"1878-8750"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypothalamic Cavernomas: Pediatric Case Report with 8.5-Year Follow-up and Review of the Literature","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2020.10.065","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}