{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T12:38:01Z","timestamp":1783600681829,"version":"3.55.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81971167"],"award-info":[{"award-number":["81971167"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.wneu.2021.10.145","type":"journal-article","created":{"date-parts":[[2021,10,26]],"date-time":"2021-10-26T19:34:32Z","timestamp":1635276872000},"page":"e166-e178","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Vestibular Schwannomas in Young Patients: A 12-Year Experience in a Single Center"],"prefix":"10.1016","volume":"158","author":[{"given":"Zehan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiashu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangye","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongyi","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2021.10.145_bib1","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1097\/MAO.0000000000002316","article-title":"Characteristics and outcomes of pediatric vestibular schwannomas","volume":"40","author":"Janz","year":"2019","journal-title":"Otol Neurotol"},{"key":"10.1016\/j.wneu.2021.10.145_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jocn.2016.05.003","article-title":"Growth rate of vestibular schwannoma","volume":"32","author":"Paldor","year":"2016","journal-title":"J\u00a0Clin Neurosci"},{"key":"10.1016\/j.wneu.2021.10.145_bib3","first-page":"121","article-title":"Vestibular schwannomas in the modern era: epidemiology, treatment trends, and disparities in management","volume":"119","author":"Babu","year":"2013","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.145_bib4","first-page":"333","article-title":"Unilateral vestibular schwannomas in childhood without evidence of neurofibromatosis: experience of 10 patients at a single institute","volume":"27","author":"Yin","year":"2017","journal-title":"Turk Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.145_bib5","author":"Malina"},{"key":"10.1016\/j.wneu.2021.10.145_bib6","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.wneu.2016.06.119","article-title":"Surgical treatment of giant vestibular schwannomas: facial nerve outcome and tumor control","volume":"94","author":"Zhang","year":"2016","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.145_bib7","first-page":"114","article-title":"Gliomas: survival differences between metropolitan and non-metropolitan counties","volume":"63","author":"Best","year":"2019","journal-title":"J\u00a0Neurosurg Sci"},{"key":"10.1016\/j.wneu.2021.10.145_bib8","doi-asserted-by":"crossref","first-page":"e1203","DOI":"10.1016\/j.wneu.2018.09.039","article-title":"MIB Index as predictor of recurrence in sporadic vestibular schwannomas","volume":"120","author":"Panigrahi","year":"2018","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.145_bib9","doi-asserted-by":"crossref","first-page":"e440","DOI":"10.1016\/j.wneu.2020.01.019","article-title":"Patient demographics influencing vestibular schwannoma size and initial management plans","volume":"136","author":"Ostler","year":"2020","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.145_bib10","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.wneu.2016.01.038","article-title":"Functional outcome of the facial nerve after surgery for vestibular schwannoma: prediction of acceptable long-term facial nerve function based on immediate postoperative facial palsy","volume":"89","author":"Lee","year":"2016","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.145_bib11","first-page":"763","article-title":"Facial nerve injury caused by vestibular Schwannoma compression: severity and adaptation to maintain normal clinical facial function","volume":"20","author":"Axon","year":"1999","journal-title":"Am J Otol"},{"key":"10.1016\/j.wneu.2021.10.145_bib12","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.wneu.2016.06.107","article-title":"Position and course of facial nerve and postoperative facial nerve results in vestibular schwannoma microsurgery","volume":"94","author":"Mastronardi","year":"2016","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.145_bib13","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0749-0712(01)00012-9","article-title":"Pathophysiology of nerve compression","volume":"18","author":"Mackinnon","year":"2002","journal-title":"Hand Clin"},{"key":"10.1016\/j.wneu.2021.10.145_bib14","doi-asserted-by":"crossref","first-page":"722","DOI":"10.3109\/00016489.2013.776178","article-title":"Predictive factors influencing facial nerve outcomes in surgery for small-sized vestibular schwannoma","volume":"133","author":"Seo","year":"2013","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.wneu.2021.10.145_bib15","doi-asserted-by":"crossref","first-page":"E14","DOI":"10.3171\/2012.6.FOCUS12163","article-title":"Surgery for vestibular schwannomas: a systematic review of complications by approach","volume":"33","author":"Ansari","year":"2012","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2021.10.145_bib16","doi-asserted-by":"crossref","first-page":"e36","DOI":"10.1016\/j.wneu.2020.04.018","article-title":"Postoperative functional preservation of facial nerve in cystic vestibular schwannoma","volume":"143","author":"Mastronardi","year":"2020","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.145_bib17","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1080\/00016489.2019.1592223","article-title":"Prognostic factors of facial nerve function after vestibular schwannoma removal via translabyrinthine approach","volume":"139","author":"Ahn","year":"2019","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.wneu.2021.10.145_bib18","doi-asserted-by":"crossref","first-page":"168","DOI":"10.3342\/ceo.2011.4.4.168","article-title":"What really decides the facial function of vestibular schwannoma surgery?","volume":"4","author":"Kim","year":"2011","journal-title":"Clin Exp Otorhinolaryngol"},{"key":"10.1016\/j.wneu.2021.10.145_bib19","author":"Mastronardi"},{"key":"10.1016\/j.wneu.2021.10.145_bib20","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1093\/neuonc\/noz153","article-title":"EANO guideline on the diagnosis and treatment of vestibular schwannoma","volume":"22","author":"Goldbrunner","year":"2020","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.wneu.2021.10.145_bib21","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1097\/MAO.0000000000001219","article-title":"Single institutional experience with observing 564 vestibular schwannomas: factors associated with tumor growth","volume":"37","author":"Hunter","year":"2016","journal-title":"Otol Neurotol"},{"key":"10.1016\/j.wneu.2021.10.145_bib22","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1093\/neuros\/nyx568","article-title":"Decision making in the wait-and-scan approach for vestibular schwannomas: is there a price to pay in terms of hearing, facial nerve, and overall outcomes?","volume":"83","author":"Prasad","year":"2018","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2021.10.145_bib23","doi-asserted-by":"crossref","first-page":"185","DOI":"10.14639\/0392-100X-N1107","article-title":"Defining current practice patterns of vestibular schwannoma management in Italy: results of a nationwide survey","volume":"41","author":"Quaranta","year":"2021","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"10.1016\/j.wneu.2021.10.145_bib24","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1093\/neuros\/nyz200","article-title":"Residual tumor volume and location predict progression after primary subtotal resection of sporadic vestibular schwannomas: a retrospective volumetric study","volume":"86","author":"Breshears","year":"2020","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2021.10.145_bib25","author":"Nakatomi"},{"key":"10.1016\/j.wneu.2021.10.145_bib26","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1159\/000156711","article-title":"Recurrence of vestibular schwannomas after surgery","volume":"21","author":"Roche","year":"2008","journal-title":"Prog Neurol Surg"},{"key":"10.1016\/j.wneu.2021.10.145_bib27","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1177\/000348941212100303","article-title":"Rate of recurrent vestibular schwannoma after total removal via different surgical approaches","volume":"121","author":"Ahmad","year":"2012","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.wneu.2021.10.145_bib28","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.cca.2019.01.011","article-title":"Ki-67 protein as a tumour proliferation marker","volume":"491","author":"Menon","year":"2019","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.wneu.2021.10.145_bib29","first-page":"1061","article-title":"Subtotal resection of vestibular schwannoma: evaluation with Ki-67 measurement, magnetic resonance imaging, and long-term observation","volume":"45","author":"Iannella","year":"2017","journal-title":"J\u00a0Int Med Res"},{"key":"10.1016\/j.wneu.2021.10.145_bib30","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/his.13967","article-title":"Intracranial cellular schwannomas: a clinicopathological study of 20 cases","volume":"76","author":"D'Almeida Costa","year":"2020","journal-title":"Histopathology"},{"key":"10.1016\/j.wneu.2021.10.145_bib31","first-page":"922","article-title":"Determinants of tumor size and growth in vestibular schwannomas","volume":"94","author":"Nutik","year":"2001","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.145_bib32","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1017\/S0022215119000549","article-title":"Ki-67 index as a predictor of vestibular schwannoma regrowth or recurrence","volume":"133","author":"Prueter","year":"2019","journal-title":"J\u00a0Laryngol Otol"},{"key":"10.1016\/j.wneu.2021.10.145_bib33","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1097\/MAO.0b013e3181967874","article-title":"Do facial nerve displacement pattern and tumor adhesion influence the facial nerve outcome in vestibular schwannoma surgery?","volume":"30","author":"Esquia-Medina","year":"2009","journal-title":"Otol Neurotol"},{"key":"10.1016\/j.wneu.2021.10.145_bib34","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/j.mcna.2018.06.011","article-title":"Facial nerve paralysis","volume":"102","author":"Owusu","year":"2018","journal-title":"Med Clin North Am"},{"key":"10.1016\/j.wneu.2021.10.145_bib35","doi-asserted-by":"crossref","first-page":"e10449","DOI":"10.7717\/peerj.10449","article-title":"Assessing anxiety, depression and quality of life in patients with peripheral facial palsy: a systematic review","volume":"8","author":"Cuenca-Mart\u00ednez","year":"2020","journal-title":"Peer J"},{"key":"10.1016\/j.wneu.2021.10.145_bib36","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.wneu.2015.03.012","article-title":"Functional preservation after planned partial resection followed by gamma knife radiosurgery for large vestibular schwannomas","volume":"84","author":"Iwai","year":"2015","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.145_bib37","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1007\/s00701-017-3194-0","article-title":"Preserving normal facial nerve function and improving hearing outcome in large vestibular schwannomas with a combined approach: planned subtotal resection followed by gamma knife radiosurgery","volume":"159","author":"Daniel","year":"2017","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2021.10.145_bib38","doi-asserted-by":"crossref","first-page":"906","DOI":"10.3174\/ajnr.A0969","article-title":"Tumor-volume changes after radiosurgery for vestibular schwannoma: implications for follow-up MR imaging protocol","volume":"29","author":"Meijer","year":"2008","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.wneu.2021.10.145_bib39","doi-asserted-by":"crossref","first-page":"262","DOI":"10.4103\/ajns.AJNS_53_17","article-title":"Facial nerve paralysis occurring 4 days following stereotactic radiosurgery for a vestibular schwannoma","volume":"14","author":"Chow","year":"2019","journal-title":"Asian J Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.145_bib40","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.amjoto.2012.09.012","article-title":"Salvage surgery of vestibular schwannoma after failed radiotherapy: the Gruppo Otologico experience and review of the literature","volume":"34","author":"Husseini","year":"2013","journal-title":"Am J Otolaryngol"},{"key":"10.1016\/j.wneu.2021.10.145_bib41","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0140-6736(12)60815-0","article-title":"Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study","volume":"380","author":"Pearce","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.wneu.2021.10.145_bib42","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1093\/jnci\/djy104","article-title":"Radiation exposure from pediatric CT scans and subsequent cancer risk in The Netherlands","volume":"111","author":"Meulepas","year":"2019","journal-title":"J\u00a0Natl Cancer Inst"},{"key":"10.1016\/j.wneu.2021.10.145_bib43","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1136\/jnnp.66.6.764","article-title":"Probability of bilateral disease in people presenting with a unilateral vestibular schwannoma","volume":"66","author":"Evans","year":"1999","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.wneu.2021.10.145_bib44","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1001\/jamaneurol.2017.1406","article-title":"Association of genetic predisposition with solitary schwannoma or meningioma in children and young adults","volume":"74","author":"Pathmanaban","year":"2017","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.wneu.2021.10.145_bib45","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3171\/2013.6.PEDS1383","article-title":"Pediatric cerebellopontine angle and internal auditory canal tumors: clinical article","volume":"12","author":"Holman","year":"2013","journal-title":"J\u00a0Neurosurg Pediatr"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875021016466?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875021016466?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T09:12:50Z","timestamp":1761815570000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875021016466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":45,"alternative-id":["S1878875021016466"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2021.10.145","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vestibular Schwannomas in Young Patients: A 12-Year Experience in a Single Center","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2021.10.145","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}