{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T05:48:24Z","timestamp":1780724904391,"version":"3.54.1"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.wneu.2021.10.158","type":"journal-article","created":{"date-parts":[[2021,10,30]],"date-time":"2021-10-30T11:19:02Z","timestamp":1635592742000},"page":"e277-e282","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["The Relationship Between APOE Gene Polymorphism and In-stent Restenosis After Stenting at the Beginning of the Vertebral Artery"],"prefix":"10.1016","volume":"158","author":[{"given":"Luxia","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinqi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qijin","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liandong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2021.10.158_bib1","doi-asserted-by":"crossref","first-page":"2618","DOI":"10.1056\/NEJMra041544","article-title":"Vertebrobasilar disease","volume":"352","author":"Savitz","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.wneu.2021.10.158_bib2","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1007\/s00062-018-0708-y","article-title":"Long-term risk of in-stent restenosis and stent fracture for extracranial vertebral artery stenting","volume":"29","author":"Li","year":"2019","journal-title":"Clin Neuroradiol"},{"key":"10.1016\/j.wneu.2021.10.158_bib3","doi-asserted-by":"crossref","first-page":"e937","DOI":"10.1016\/j.wneu.2017.11.112","article-title":"The incidence and risk factors of in-stent restenosis for vertebrobasilar artery stenting","volume":"110","author":"Zheng","year":"2018","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2021.10.158_bib4","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1583\/07-2175.1","article-title":"Risk factors for in-stent restenosis after vertebral ostium stenting","volume":"15","author":"Taylor","year":"2008","journal-title":"J\u00a0Endovasc Ther"},{"key":"10.1016\/j.wneu.2021.10.158_bib5","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1186\/s12872-020-01798-2","article-title":"The characteristics and risk factors of in-stent restenosis in patients with percutaneous coronary intervention: what can we do","volume":"20","author":"Wang","year":"2020","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.wneu.2021.10.158_bib6","doi-asserted-by":"crossref","first-page":"337","DOI":"10.4070\/kcj.2018.0103","article-title":"Current management of in-stent restenosis","volume":"48","author":"Her","year":"2018","journal-title":"Korean Circ J"},{"key":"10.1016\/j.wneu.2021.10.158_bib7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s11886-018-0952-4","article-title":"Therapeutic options for in-stent restenosis","volume":"20","author":"Nicolais","year":"2018","journal-title":"Curr Cardiol Rep"},{"key":"10.1016\/j.wneu.2021.10.158_bib8","first-page":"292","article-title":"Neoatherosclerosis: from basic principles to intravascular imaging","volume":"66","author":"Nicol","year":"2018","journal-title":"Minerva Cardioangiol"},{"key":"10.1016\/j.wneu.2021.10.158_bib9","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.atherosclerosis.2018.02.015","article-title":"Hyperlipidemia induces typical atherosclerosis development in LDLR and APOE deficient rats","volume":"271","author":"Zhao","year":"2018","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.wneu.2021.10.158_bib10","first-page":"328","article-title":"Comparison of drug-eluting and bare metal stents for extracranial vertebral artery stenting","volume":"15","author":"Maciejewski","year":"2019","journal-title":"Postepy Kardiol Interwencyjnej"},{"key":"10.1016\/j.wneu.2021.10.158_bib11","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/ana.20204","article-title":"New England Medical Center Posterior Circulation registry","volume":"56","author":"Caplan","year":"2004","journal-title":"Ann Neurol"},{"key":"10.1016\/j.wneu.2021.10.158_bib12","first-page":"1733","article-title":"Efficacy and safety of stenting for elderly patients with severe and symptomatic carotid artery stenosis: a critical meta-analysis of randomized controlled trials","volume":"10","author":"Ouyang","year":"2015","journal-title":"Clin Interv Aging"},{"key":"10.1016\/j.wneu.2021.10.158_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jstrokecerebrovasdis.2012.12.004","article-title":"The natural history of vertebral artery origin stenosis","volume":"23","author":"Thompson","year":"2014","journal-title":"J\u00a0Stroke Cerebrovasc Dis"},{"key":"10.1016\/j.wneu.2021.10.158_bib14","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/j.jvs.2011.09.084","article-title":"Percutaneous transluminal angioplasty and stenting in patients with proximal vertebral artery stenosis","volume":"55","author":"Antoniou","year":"2012","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.wneu.2021.10.158_bib15","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1089\/rej.2011.1169","article-title":"The genetics of the human APOE polymorphism","volume":"14","author":"Seripa","year":"2011","journal-title":"Rejuvenation Res"},{"key":"10.1016\/j.wneu.2021.10.158_bib16","doi-asserted-by":"crossref","first-page":"173","DOI":"10.4103\/0022-3859.68629","article-title":"Apolipoprotein E gene polymorphism and total serum cholesterol level in Iranian population","volume":"56","author":"Bazzaz","year":"2010","journal-title":"J\u00a0Postgrad Med"},{"key":"10.1016\/j.wneu.2021.10.158_bib17","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1159\/000443568","article-title":"Association between Apolipoprotein \u03b54 Gene Polymorphism and Risk of Ischemic Stroke: A Meta-Analysis","volume":"23","author":"Kumar","year":"2016","journal-title":"Ann Neurosci"},{"key":"10.1016\/j.wneu.2021.10.158_bib18","doi-asserted-by":"crossref","first-page":"18153","DOI":"10.1038\/s41598-019-54541-z","article-title":"Apolipoprotein E deficient rats generated via zinc-finger nucleases exhibit pronounced in-stent restenosis","volume":"9","author":"Cornelissen","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.wneu.2021.10.158_bib19","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.atherosclerosis.2009.09.071","article-title":"A\u00a0novel mouse model of in-stent restenosis","volume":"209","author":"Rodriguez-Menocal","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.wneu.2021.10.158_bib20","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1536\/ihj.20-139","article-title":"Incidence and predictors of neoatherosclerosis in patients with early in-stent restenosis determined using optical coherence tomography","volume":"61","author":"Meng","year":"2020","journal-title":"Int Heart J"},{"key":"10.1016\/j.wneu.2021.10.158_bib21","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1155\/2013\/472845","article-title":"Baseline LDL-C and Lp(a) elevations portend a high risk of coronary revascularization in patients after stent placement","volume":"35","author":"Cai","year":"2013","journal-title":"Dis Markers"},{"key":"10.1016\/j.wneu.2021.10.158_bib22","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.ijcard.2011.01.058","article-title":"Impact of out-stent plaque volume on in-stent intimal hyperplasia: results from serial volumetric analysis with high-gain intravascular ultrasound","volume":"158","author":"Tada","year":"2012","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.wneu.2021.10.158_bib23","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.ihj.2013.10.003","article-title":"Apolipoproteins AI\/B\/E gene polymorphism and their plasma levels in patients with coronary artery disease in a tertiary care-center of Eastern India","volume":"65","author":"Biswas","year":"2013","journal-title":"Indian Heart J"},{"key":"10.1016\/j.wneu.2021.10.158_bib24","first-page":"2149","article-title":"Apolipoprotein E gene polymorphism and its effect on plasma lipids in arteriosclerosis","volume":"7","author":"Zende","year":"2013","journal-title":"J\u00a0Clin Diagn Res"},{"key":"10.1016\/j.wneu.2021.10.158_bib25","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1016\/j.clinbiochem.2008.09.109","article-title":"Low basal levels of circulating adiponectin in patients undergoing coronary stenting predict in-stent restenosis, independently of basal levels of inflammatory markers: lipoprotein associated phospholipase A2, and myeloperoxidase","volume":"41","author":"Moldoveanu","year":"2008","journal-title":"Clin Biochem"},{"key":"10.1016\/j.wneu.2021.10.158_bib26","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1476-511X-13-41","article-title":"Baseline elevated Lp-PLA2 is associated with increased risk for re-stenosis after stent placement","volume":"13","author":"Zheng","year":"2014","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.wneu.2021.10.158_bib27","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1177\/00369330211034809","article-title":"Relationship between Lp-PLA2 and in-stent restenosis after coronary stenting: a 3-year follow-up study","volume":"66","author":"Sheng","year":"2021","journal-title":"Scott Med J"},{"key":"10.1016\/j.wneu.2021.10.158_bib28","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s13167-011-0063-4","article-title":"Lipoprotein associated phospholipase A: role in atherosclerosis and utility as a biomarker for cardiovascular risk","volume":"2","author":"Colley","year":"2011","journal-title":"EPMA J"},{"key":"10.1016\/j.wneu.2021.10.158_bib29","doi-asserted-by":"crossref","first-page":"263","DOI":"10.3109\/10408363.2014.913549","article-title":"Critical appraisal of inflammatory markers in cardiovascular risk stratification","volume":"51","author":"Krintus","year":"2014","journal-title":"Crit Rev Clin Lab Sci"},{"key":"10.1016\/j.wneu.2021.10.158_bib30","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1373\/clinchem.2004.032656","article-title":"Preprocedural C-reactive protein is not associated with angiographic restenosis or target lesion revascularization after coronary artery stent placement","volume":"50","author":"Rittersma","year":"2004","journal-title":"Clin Chem"},{"key":"10.1016\/j.wneu.2021.10.158_bib31","first-page":"1002","article-title":"Association of smoking with restenosis and major adverse cardiac events after coronary stenting: a meta-analysis","volume":"31","author":"Hu","year":"2015","journal-title":"Pak J Med Sci"},{"key":"10.1016\/j.wneu.2021.10.158_bib32","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1186\/s12933-020-01111-7","article-title":"Visit-to-visit HbA(1c) variability is associated with in-stent restenosis in patients with type 2 diabetes after percutaneous coronary intervention","volume":"19","author":"Yang","year":"2020","journal-title":"Cardiovasc Diabetol"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875021016697?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875021016697?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T09:13:34Z","timestamp":1761815614000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875021016697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":32,"alternative-id":["S1878875021016697"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2021.10.158","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Relationship Between APOE Gene Polymorphism and In-stent Restenosis After Stenting at the Beginning of the Vertebral Artery","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2021.10.158","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}