{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:24:34Z","timestamp":1790706274901,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,23]],"date-time":"2023-12-23T00:00:00Z","timestamp":1703289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005743","name":"Catholic University of the Sacred Heart","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005743","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.wneu.2023.12.117","type":"journal-article","created":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T02:10:04Z","timestamp":1703556604000},"page":"e432-e439","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Effect of General Anesthesia Versus Conscious Sedation\/Local Anesthesia on the Outcome of Patients with Minor Stroke and Isolated M2 Occlusion Undergoing Immediate Thrombectomy: A Retrospective Multicenter Matched Analysis"],"prefix":"10.1016","volume":"183","author":[{"given":"Iacopo","family":"Valente","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8080-3916","authenticated-orcid":false,"given":"Andrea M.","family":"Alexandre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7164-6584","authenticated-orcid":false,"given":"Francesca","family":"Col\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5714-5353","authenticated-orcid":false,"given":"Valerio","family":"Brunetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1604-6594","authenticated-orcid":false,"given":"Giovanni","family":"Frisullo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna","family":"Camilli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5133-6650","authenticated-orcid":false,"given":"Anne","family":"Falcou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1316-0383","authenticated-orcid":false,"given":"Luca","family":"Scarcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4264-1151","authenticated-orcid":false,"given":"Riccardo","family":"Gigli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2370-840X","authenticated-orcid":false,"given":"Irene","family":"Scala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5698-2336","authenticated-orcid":false,"given":"Pier A.","family":"Rizzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3793-5566","authenticated-orcid":false,"given":"Serena","family":"Abruzzese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Milonia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariangela","family":"Piano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Macera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Ruggiero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7167-7594","authenticated-orcid":false,"given":"Valerio","family":"Da Ros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1280-3022","authenticated-orcid":false,"given":"Luigi","family":"Bellini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido A.","family":"Lazzarotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirco","family":"Cosottini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio A.","family":"Caragliano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio L.","family":"Vinci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6905-3627","authenticated-orcid":false,"given":"Joseph D.","family":"Gabrieli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Causin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Panni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Roveri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0432-5414","authenticated-orcid":false,"given":"Nicola","family":"Limbucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3941-7383","authenticated-orcid":false,"given":"Francesco","family":"Arba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Renieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5503-3147","authenticated-orcid":false,"given":"Simone","family":"Ferretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7691-8999","authenticated-orcid":false,"given":"Marco","family":"Pileggi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Bianco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele G.","family":"Romano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5912-3345","authenticated-orcid":false,"given":"Giulia","family":"Frauenfelder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7546-4251","authenticated-orcid":false,"given":"Vittorio","family":"Semeraro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria P.","family":"Ganimede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3992-9071","authenticated-orcid":false,"given":"Emilio","family":"Lozupone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8727-9141","authenticated-orcid":false,"given":"Antonio","family":"Fasano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvis","family":"Lafe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna M.","family":"Cavallini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2224-8002","authenticated-orcid":false,"given":"Federico","family":"Mazzacane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Bergui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8295-9271","authenticated-orcid":false,"given":"Aldobrando","family":"Broccolini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2558-8838","authenticated-orcid":false,"given":"Alessandro","family":"Pedicelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2023.12.117_bib1","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1016\/S0140-6736(16)00163-X","article-title":"Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials","volume":"387","author":"Goyal","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.wneu.2023.12.117_bib2","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1007\/s12028-011-9638-0","article-title":"Increased rate of aspiration pneumonia and poor Discharge outcome among acute ischemic stroke patients following intubation for endovascular treatment","volume":"16","author":"Hassan","year":"2012","journal-title":"Neurocrit Care"},{"key":"10.1016\/j.wneu.2023.12.117_bib3","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1161\/STROKEAHA.117.016554","article-title":"General anesthesia versus conscious sedation for endovascular treatment of acute ischemic stroke: the AnStroke trial (anesthesia during stroke)","volume":"48","author":"L\u00f6whagen Hend\u00e9n","year":"2017","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2023.12.117_bib4","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1001\/jama.2016.16623","article-title":"Effect of conscious sedation vs general anesthesia on early neurological improvement among patients with ischemic stroke undergoing endovascular thrombectomy: arandomized clinical trial","volume":"316","author":"Sch\u00f6nenberger","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.wneu.2023.12.117_bib5","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1001\/jamaneurol.2017.4474","article-title":"Effect of general anesthesia and conscious sedation during endovascular therapy on infarct growth and clinical outcomes in acute ischemic stroke: arandomized clinical trial","volume":"75","author":"Simonsen","year":"2018","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.wneu.2023.12.117_bib6","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1001\/jama.2019.11455","article-title":"Association of general anesthesia vs procedural sedation with functional outcome among patients with acute ischemic stroke undergoing thrombectomy: asystematic review and meta-analysis","volume":"322","author":"Sch\u00f6nenberger","year":"2019","journal-title":"JAMA"},{"key":"10.1016\/j.wneu.2023.12.117_bib7","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1212\/WNL.0000000000002976","article-title":"The effect of anesthetic management during intra-arterial therapy for acute stroke in MR CLEAN","volume":"87","author":"Berkhemer","year":"2016","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2023.12.117_bib8","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S1474-4422(17)30407-6","article-title":"Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data","volume":"17","author":"Campbell","year":"2018","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.wneu.2023.12.117_bib9","doi-asserted-by":"crossref","first-page":"e97","DOI":"10.1212\/WNL.0000000000008674","article-title":"Anesthetic management during endovascular treatment of acute ischemic stroke in the MR CLEAN Registry","volume":"94","author":"Goldhoorn","year":"2020","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2023.12.117_bib10","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1001\/jamaneurol.2023.0413","article-title":"Outcomes after endovascular therapy with procedural sedation vs general anesthesia in patients with acute ischemic stroke: the AMETIS randomized clinical trial","volume":"80","author":"Chabanne","year":"2023","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.wneu.2023.12.117_bib11","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1136\/neurintsurg-2022-018662","article-title":"Effects of endovascular therapy for mild stroke due to proximal or M2 occlusions: meta-analysis","volume":"15","author":"Lin","year":"2023","journal-title":"J\u00a0Neurointerv Surg"},{"key":"10.1016\/j.wneu.2023.12.117_bib12","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.1007\/s10072-021-05771-5","article-title":"Mechanical thrombectomy in acute ischemic stroke due to large vessel occlusion in the anterior circulation and low baseline National Institute of Health Stroke Scale score: a multicenter retrospective matched analysis","volume":"43","author":"Alexandre","year":"2022","journal-title":"Neurol Sci"},{"key":"10.1016\/j.wneu.2023.12.117_bib13","first-page":"2924","article-title":"Endovascular treatment achieves better outcomes than best medical management in patients with M2 occlusion and high stroke severity: a meta-analysis","volume":"270","author":"Guo","year":"2023","journal-title":"J\u00a0Neurol"},{"key":"10.1016\/j.wneu.2023.12.117_bib14","doi-asserted-by":"crossref","first-page":"e475","DOI":"10.1136\/jnis-2022-019959","article-title":"Endovascular treatment versus medical management for mild stroke with acute anterior circulation large vessel occlusion: a meta-analysis","volume":"15","author":"Qin","year":"2023","journal-title":"J\u00a0Neurointerv Surg"},{"key":"10.1016\/j.wneu.2023.12.117_bib15","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1016\/S0140-6736(00)02237-6","article-title":"Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS Study Group. Alberta Stroke Programme Early CT Score","volume":"355","author":"Barber","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.wneu.2023.12.117_bib16","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1148\/radiol.15142256","article-title":"Multiphase CT angiography: anew tool for the imaging triage of patients with acute ischemic stroke","volume":"275","author":"Menon","year":"2015","journal-title":"Radiology"},{"key":"10.1016\/j.wneu.2023.12.117_bib17","doi-asserted-by":"crossref","first-page":"E40","DOI":"10.3174\/ajnr.A5179","article-title":"Caution; confusion ahead","volume":"38","author":"Capocci","year":"2017","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.wneu.2023.12.117_bib18","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1136\/neurintsurg-2015-012191","article-title":"What constitutes the M1 segment of the middle cerebral artery?","volume":"8","author":"Goyal","year":"2016","journal-title":"J\u00a0Neurointerv Surg"},{"key":"10.1016\/j.wneu.2023.12.117_bib19","doi-asserted-by":"crossref","first-page":"e344","DOI":"10.1161\/STROKEAHA.118.022606","volume":"50","author":"Powers","year":"2019","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2023.12.117_bib20","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1136\/neurintsurg-2020-016427","article-title":"Benefit of endovascular thrombectomy for M2 middle cerebral artery occlusion in the ARISE II study","volume":"13","author":"de Havenon","year":"2021","journal-title":"J\u00a0Neurointerv Surg"},{"key":"10.1016\/j.wneu.2023.12.117_bib21","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s00234-014-1460-x","article-title":"Scoring flow restoration in cerebral angiograms after endovascular revascularization in acute ischemic stroke patients","volume":"57","author":"Gerber","year":"2015","journal-title":"Neuroradiology"},{"key":"10.1016\/j.wneu.2023.12.117_bib22","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1136\/neurintsurg-2015-011839","article-title":"Proposed methodology and classification of Infarct in New Territory (INT) after endovascular stroke treatment","volume":"9","author":"Goyal","year":"2017","journal-title":"J\u00a0Neurointerv Surg"},{"key":"10.1016\/j.wneu.2023.12.117_bib23","doi-asserted-by":"crossref","first-page":"e198","DOI":"10.1136\/jnis-2022-019557","article-title":"Mechanical thrombectomy in minor stroke due to isolated M2 occlusion: a multicenter retrospective matched analysis","volume":"15","author":"Alexandre","year":"2023","journal-title":"J\u00a0Neurointerv Surg"},{"key":"10.1016\/j.wneu.2023.12.117_bib24","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/bimj.200810488","article-title":"Some methods of propensity-score matching had superior performance to others: results of an empirical investigation and Monte Carlo simulations","volume":"51","author":"Austin","year":"2009","journal-title":"Biom J"},{"key":"10.1016\/j.wneu.2023.12.117_bib25","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1002\/ana.26331","article-title":"Endovascular thrombectomy versus medical management in isolated M2 occlusions: pooled patient-level analysis from the EXTEND-IA trials, INSPIRE, and SELECT studies","volume":"91","author":"Sarraj","year":"2022","journal-title":"Ann Neurol"},{"key":"10.1016\/j.wneu.2023.12.117_bib26","doi-asserted-by":"crossref","first-page":"e1655","DOI":"10.1212\/WNL.0000000000207066","article-title":"General anesthesia compared with non-GA in endovascular thrombectomy for ischemic stroke: asystematic review and meta-analysis of randomized controlled trials","volume":"100","author":"Campbell","year":"2023","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2023.12.117_bib27","doi-asserted-by":"crossref","first-page":"e336","DOI":"10.1212\/WNL.0000000000201384","article-title":"Thrombectomy outcomes with general vs nongeneral anesthesia: apooled patient-level analysis from the EXTEND-IA trials and selectstudy","volume":"100","author":"Sarraj","year":"2023","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2023.12.117_bib28","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1136\/jnis-2023-020210","article-title":"Effect of anesthetic strategies on distal stroke thrombectomy in the anterior and posterior cerebral artery","volume":"16","author":"Meyer","year":"2024","journal-title":"J Neurointerv Surg"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875023018508?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875023018508?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T20:52:13Z","timestamp":1749675133000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875023018508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":28,"alternative-id":["S1878875023018508"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2023.12.117","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of General Anesthesia Versus Conscious Sedation\/Local Anesthesia on the Outcome of Patients with Minor Stroke and Isolated M2 Occlusion Undergoing Immediate Thrombectomy: A Retrospective Multicenter Matched Analysis","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2023.12.117","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}