{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T07:11:21Z","timestamp":1772176281666,"version":"3.50.1"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009104","name":"Department of Health Research, India","doi-asserted-by":"publisher","award":["DHR-ICMR\/GIA\/18\/18\/2020"],"award-info":[{"award-number":["DHR-ICMR\/GIA\/18\/18\/2020"]}],"id":[{"id":"10.13039\/501100009104","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009104","name":"Department of Health Research, India","doi-asserted-by":"publisher","award":["ICMR-CAR-5\/3\/8\/1\/2022\/MDMS"],"award-info":[{"award-number":["ICMR-CAR-5\/3\/8\/1\/2022\/MDMS"]}],"id":[{"id":"10.13039\/501100009104","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.wneu.2024.05.014","type":"journal-article","created":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T03:27:15Z","timestamp":1715311635000},"page":"e937-e948","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Clinicoradiological Parameters and Biochemical and Molecular Alterations Predicting Remission and Recurrence After Surgical Treatment of Corticotroph Adenomas\u2014Cushing Disease"],"prefix":"10.1016","volume":"187","author":[{"given":"Nidhisha","family":"Sadhwani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4083-6799","authenticated-orcid":false,"given":"Santanu Kumar","family":"Bora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Deepa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varidh","family":"Katiyar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amol","family":"Raheja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajay","family":"Garg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vaishali","family":"Suri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhil","family":"Tandon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehar Chand","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Khadgawat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0464-0860","authenticated-orcid":false,"given":"Ashish","family":"Suri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2024.05.014_bib1","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1210\/er.2013-1048","article-title":"The treatment of cushing\u2019s disease","volume":"36","author":"Pivonello","year":"2015","journal-title":"Endocr Rev"},{"key":"10.1016\/j.wneu.2024.05.014_bib2","doi-asserted-by":"crossref","first-page":"6348","DOI":"10.1210\/jc.2003-032180","article-title":"Transsphenoidal microsurgery for Cushing\u2019s disease: initial outcome and long-term results","volume":"89","author":"Hammer","year":"2004","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib3","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1159\/000258677","article-title":"Biochemical predictors of outcome of pituitary surgery for Cushing\u2019s disease","volume":"91","author":"Alwani","year":"2010","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.wneu.2024.05.014_bib4","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1007\/s00701-017-3140-1","article-title":"Efficacy of endoscopic endonasal transsphenoidal surgery for Cushing\u2019s disease in 230 patients with positive and negative MRI","volume":"159","author":"Cebula","year":"2017","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2024.05.014_bib5","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1530\/eje.1.02133","article-title":"Transsphenoidal pituitary surgery via the endoscopic technique: results in 35 consecutive patients with Cushing\u2019s disease","volume":"154","author":"Netea-Maier","year":"2006","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.wneu.2024.05.014_bib6","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1111\/j.1365-2265.2008.03334.x","article-title":"Repeated transsphenoidal pituitary surgery (TS) via the endoscopic technique: a good therapeutic option for recurrent or persistent Cushing\u2019s disease (CD)","volume":"70","author":"Wagenmakers","year":"2009","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.wneu.2024.05.014_bib7","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0950-351X(95)80418-8","article-title":"Surgical management of pituitary adenomas","volume":"9","author":"Laws","year":"1995","journal-title":"Baillieres Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib8","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1365-2265.1993.tb00975.x","article-title":"Transsphenoidal resection in Cushing\u2019s disease: undetectable serum cortisol as the definition of successful treatment","volume":"38","author":"Trainer","year":"1993","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.wneu.2024.05.014_bib9","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/ng.3166","article-title":"Mutations in the deubiquitinase gene USP8 cause Cushing\u2019s disease","volume":"47","author":"Reincke","year":"2015","journal-title":"Nat Genet"},{"key":"10.1016\/j.wneu.2024.05.014_bib10","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1093\/neuonc\/noz109","article-title":"Driver mutations in USP8 wild-type Cushing\u2019s disease","volume":"21","author":"Sbiera","year":"2019","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.wneu.2024.05.014_bib11","first-page":"1526","article-title":"The diagnosis of Cushing's syndrome: an endocrine society clinical practice guideline","volume":"93","author":"Nieman","year":"2008","journal-title":"Clin Biochem Rev"},{"key":"10.1016\/j.wneu.2024.05.014_bib12","doi-asserted-by":"crossref","first-page":"R12","DOI":"10.1530\/EC-16-0029","article-title":"Bilateral inferior petrosal sinus sampling","volume":"5","author":"Zampetti","year":"2016","journal-title":"Endocrine Connections"},{"key":"10.1016\/j.wneu.2024.05.014_bib13","first-page":"138","article-title":"[Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue]","volume":"8","author":"Remmele","year":"1987","journal-title":"Pathologe"},{"key":"10.1016\/j.wneu.2024.05.014_bib14","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1210\/jc.2012-3604","article-title":"Outcome of surgical treatment of 200 children with Cushing\u2019s disease","volume":"98","author":"Lonser","year":"2013","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib15","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1016\/S0140-6736(06)68699-6","article-title":"Cushing\u2019s syndrome","volume":"367","author":"Newell-Price","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.wneu.2024.05.014_bib16","doi-asserted-by":"crossref","first-page":"5593","DOI":"10.1210\/jc.2003-030871","article-title":"Diagnosis and complications of Cushing\u2019s syndrome: a consensus statement","volume":"88","author":"Arnaldi","year":"2003","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib17","first-page":"423","article-title":"A\u00a0critical evaluation of transsphenoidal pituitary surgery in the treatment of Cushing\u2019s disease: prediction of outcome","volume":"123","author":"Arnott","year":"1990","journal-title":"Acta Endocrinol"},{"key":"10.1016\/j.wneu.2024.05.014_bib18","first-page":"195","article-title":"Transsphenoidal microsurgical management of Cushing\u2019s disease. Report of 100 cases","volume":"59","author":"Boggan","year":"1983","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2024.05.014_bib19","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/neurosurgery\/16.CN_suppl_1.185","article-title":"Transphenoidal microsurgery of the normal and pathological pituitary","volume":"16","author":"Hardy","year":"1969","journal-title":"Clin Neurosurg"},{"key":"10.1016\/j.wneu.2024.05.014_bib20","doi-asserted-by":"crossref","first-page":"R143","DOI":"10.1530\/EJE-14-0556","article-title":"Management of endocrine disease: mortality remains increased in Cushing\u2019s disease despite biochemical remission: a systematic review and meta-analysis","volume":"172","author":"Haalen","year":"2015","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.wneu.2024.05.014_bib21","first-page":"117","article-title":"Incidence and late prognosis of cushing\u2019s syndrome: a population-based study","volume":"86","author":"Lindholm","year":"2001","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.beem.2021.101485","article-title":"The definition of remission and recurrence of Cushing\u2019s disease","volume":"35","author":"Hinojosa-Amaya","year":"2021","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib23","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s11102-020-01066-8","article-title":"Outcomes of pituitary surgery for Cushing\u2019s disease: a systematic review and meta-analysis","volume":"23","author":"Stroud","year":"2020","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2024.05.014_bib24","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0720-048X(94)90333-6","article-title":"Pituitary microadenomas: diagnosis with dynamic serial CT, conventional CT and T1-weighted MR imaging before and after injection of gadolinium","volume":"18","author":"Stadnik","year":"1994","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.wneu.2024.05.014_bib25","first-page":"1183","article-title":"The accuracy of CT and MR evaluation of the sella turcica for detection of adrenocorticotropic hormone-secreting adenomas in Cushing disease","volume":"14","author":"Buchfelder","year":"1993","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.wneu.2024.05.014_bib26","doi-asserted-by":"crossref","first-page":"e46","DOI":"10.1016\/j.wneu.2019.08.165","article-title":"Management of cushing\u2019s disease: changing trend from microscopic to endoscopic surgery","volume":"134","author":"Bora","year":"2020","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2024.05.014_bib27","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s11102-011-0347-7","article-title":"Clinical factors involved in the recurrence of pituitary adenomas after surgical remission: a structured review and meta-analysis","volume":"15","author":"Roelfsema","year":"2012","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2024.05.014_bib28","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1210\/jc.2005-1204","article-title":"Clinical review: early morning cortisol levels as a predictor of remission after transsphenoidal surgery for Cushing\u2019s disease","volume":"91","author":"Esposito","year":"2006","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib29","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1210\/jc.2009-1672","article-title":"Delayed remission after transsphenoidal surgery in patients with cushing\u2019s disease","volume":"95","author":"Valassi","year":"2010","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib30","first-page":"1268","article-title":"Dynamics of postoperative serum cortisol after transsphenoidal surgery for Cushing\u2019s disease: implications for immediate reoperation and remission","volume":"129","author":"Mayberg","year":"2018","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2024.05.014_bib31","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/cen.12300","article-title":"Evaluation of Cushing\u2019s disease remission after transsphenoidal surgery based on early serum cortisol dynamics","volume":"80","author":"Costenaro","year":"2014","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.wneu.2024.05.014_bib32","doi-asserted-by":"crossref","first-page":"2454","DOI":"10.1210\/jc.2007-2734","article-title":"Treatment of adrenocorticotropin-dependent Cushing\u2019s syndrome: a consensus statement","volume":"93","author":"Biller","year":"2008","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib33","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1007\/s11102-012-0455-z","article-title":"Remission rate after transsphenoidal surgery in patients with pathologically confirmed Cushing\u2019s disease, the role of cortisol, ACTH assessment and immediate reoperation: a large single center experience","volume":"16","author":"Hameed","year":"2013","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2024.05.014_bib34","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1007\/s11154-021-09626-4","article-title":"Paediatric Cushing\u2019s disease: epidemiology, pathogenesis, clinical management and outcome","volume":"22","author":"Ferrigno","year":"2021","journal-title":"Rev Endocr Metab Disord"},{"key":"10.1016\/j.wneu.2024.05.014_bib35","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s12020-019-02036-2","article-title":"Treatment challenges in pediatric Cushing\u2019s disease: review of the literature with particular emphasis on predictive factors for the disease recurrence","volume":"66","author":"Pasternak-Pietrzak","year":"2019","journal-title":"Endocrine"},{"key":"10.1016\/j.wneu.2024.05.014_bib36","doi-asserted-by":"crossref","first-page":"369","DOI":"10.4158\/EP10143.OR","article-title":"Cushing disease in children and adolescents: twenty years\u2019 experience in a tertiary care center in India","volume":"17","author":"Shah","year":"2011","journal-title":"Endocr Pract"},{"key":"10.1016\/j.wneu.2024.05.014_bib37","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.jamcollsurg.2009.02.054","article-title":"Bilateral adrenalectomy for refractory Cushing disease: a safe and definitive therapy","volume":"208","author":"Smith","year":"2009","journal-title":"J\u00a0Am Coll Surg"},{"key":"10.1016\/j.wneu.2024.05.014_bib38","doi-asserted-by":"crossref","first-page":"3939","DOI":"10.1210\/jc.2013-1470","article-title":"Clinical review: outcome of bilateral adrenalectomy in Cushing\u2019s syndrome: a systematic review","volume":"98","author":"Ritzel","year":"2013","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib39","doi-asserted-by":"crossref","DOI":"10.3171\/2014.10.FOCUS14684","article-title":"The role of bilateral adrenalectomy in the treatment of refractory Cushing\u2019s disease","volume":"38","author":"Wong","year":"2015","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2024.05.014_bib40","first-page":"440","article-title":"Diagnosis and management of cushing\u2019s syndrome: results of an Italian multicentre study. Study group of the Italian society of endocrinology on the pathophysiology of the hypothalamic-pituitary-adrenal Axis","volume":"84","author":"Invitti","year":"1999","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib41","first-page":"347","article-title":"Value of pituitary gland MRI at 7 T in Cushing\u2019s disease and relationship to inferior petrosal sinus sampling: case report","volume":"130","author":"Law","year":"2019","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2024.05.014_bib42","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.wneu.2022.03.076","article-title":"MRI\u2013negative cushing\u2019s disease: a review on therapeutic management","volume":"162","author":"Sabahi","year":"2022","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2024.05.014_bib43","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.3174\/ajnr.A5244","article-title":"Role of high-resolution dynamic contrast-enhanced MRI with golden-angle radial sparse parallel reconstruction to identify the normal pituitary gland in patients with macroadenomas","volume":"38","author":"Sen","year":"2017","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.wneu.2024.05.014_bib44","doi-asserted-by":"crossref","first-page":"V7","DOI":"10.3171\/2023.4.FOCVID2318","article-title":"Management protocol and surgical techniques for MRI-Negative Cushing\u2019s disease: a series of 6 cases","volume":"9","author":"Sadhwani","year":"2023","journal-title":"Neurosurg Focus Video"},{"key":"10.1016\/j.wneu.2024.05.014_bib45","doi-asserted-by":"crossref","DOI":"10.3171\/foc.2007.23.3.8","article-title":"Cushing disease: use of perioperative serum cortisol measurements in early determination of success following pituitary surgery","volume":"23","author":"Krikorian","year":"2007","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2024.05.014_bib46","doi-asserted-by":"crossref","first-page":"e4232","DOI":"10.1210\/clinem\/dgac341","article-title":"Cushing mortality in remission: not out of the woods","volume":"107","author":"Kelsall","year":"2022","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib47","doi-asserted-by":"crossref","DOI":"10.1210\/clinem\/dgaa291","article-title":"Excess morbidity persists in patients with cushing\u2019s disease during long-term remission: a Swedish nationwide study","volume":"105","author":"Papakokkinou","year":"2020","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.05.014_bib48","doi-asserted-by":"crossref","DOI":"10.1111\/jne.13134","article-title":"Role of radiosurgery in the treatment of Cushing\u2019s disease","volume":"34","author":"Losa","year":"2022","journal-title":"J\u00a0Neuroendocrinol"},{"key":"10.1016\/j.wneu.2024.05.014_bib49","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1038\/cr.2015.20","article-title":"Recurrent gain-of-function USP8 mutations in Cushing\u2019s disease","volume":"25","author":"Ma","year":"2015","journal-title":"Cell Res"},{"key":"10.1016\/j.wneu.2024.05.014_bib50","article-title":"Identification of recurrent USP48 and BRAF mutations in Cushing\u2019s disease","volume":"9","author":"Chen","year":"2018","journal-title":"Nat Commun"},{"key":"10.1016\/j.wneu.2024.05.014_bib51","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1080\/13543784.2017.1266338","article-title":"Currently used and investigational drugs for Cushing's disease","volume":"26","author":"Ciato","year":"2017","journal-title":"Expet Opin Invest Drugs"},{"key":"10.1016\/j.wneu.2024.05.014_bib52","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1677\/joe.1.05616","article-title":"Expression of epidermal growth factor receptor in neoplastic pituitary cells: evidence for a role in corticotropinoma cells","volume":"183","author":"Theodoropoulou","year":"2004","journal-title":"J\u00a0Endocrinol"},{"key":"10.1016\/j.wneu.2024.05.014_bib53","doi-asserted-by":"crossref","first-page":"4712","DOI":"10.1172\/JCI60417","article-title":"EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas","volume":"121","author":"Fukuoka","year":"2011","journal-title":"J\u00a0Clin Invest"},{"issue":"suppl 2","key":"10.1016\/j.wneu.2024.05.014_bib54","doi-asserted-by":"crossref","first-page":"ii62","DOI":"10.1136\/ard.2004.028274","article-title":"Mitogen activated protein kinases as targets for development of novel anti-inflammatory drugs","volume":"63","author":"Karin","year":"2004","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.wneu.2024.05.014_bib55","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/cen.13802","article-title":"The USP8 mutational status may predict long-term remission in patients with Cushing\u2019s disease","volume":"89","author":"Albani","year":"2018","journal-title":"Clin Endocrinol (Oxf)"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875024007678?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875024007678?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T01:22:22Z","timestamp":1749691342000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875024007678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":55,"alternative-id":["S1878875024007678"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2024.05.014","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinicoradiological Parameters and Biochemical and Molecular Alterations Predicting Remission and Recurrence After Surgical Treatment of Corticotroph Adenomas\u2014Cushing Disease","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2024.05.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}