{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T00:42:17Z","timestamp":1793407337264,"version":"4.5.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.wneu.2024.08.027","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T03:57:51Z","timestamp":1724385471000},"page":"e41-e47","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Silent Corticotroph Adenomas Demonstrate Predilection for Sphenoid Sinus, Cavernous Sinus, and Clival Invasion Compared with Other Subtypes"],"prefix":"10.1016","volume":"191","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9244-700X","authenticated-orcid":false,"given":"Alexander S.","family":"Himstead","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3018-9897","authenticated-orcid":false,"given":"Alicia C.","family":"Wells","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8208-8813","authenticated-orcid":false,"given":"Joshua S.","family":"Kurtz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6596-6231","authenticated-orcid":false,"given":"Matthew R.","family":"Moldenhauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1550-0986","authenticated-orcid":false,"given":"Jordan L.","family":"Davies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianna M.","family":"Fote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9869-8114","authenticated-orcid":false,"given":"Benjamin F.","family":"Bitner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3788-1860","authenticated-orcid":false,"given":"Eleanor","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Mohyeldin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank P.K.","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3475-0718","authenticated-orcid":false,"given":"Eduard C.","family":"Kuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2024.08.027_bib1","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1001\/jama.2016.19699","article-title":"Diagnosis and treatment of pituitary adenomas: a review","volume":"317","author":"Molitch","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/j.wneu.2024.08.027_bib2","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1530\/EJE-16-0206","article-title":"Treatment of clinically nonfunctioning pituitary adenomas with dopamine agonists","volume":"175","author":"Greenman","year":"2016","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.wneu.2024.08.027_bib3","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ecl.2014.10.010","article-title":"Outcomes of endoscopic transsphenoidal pituitary surgery","volume":"44","author":"Dallapiazza","year":"2015","journal-title":"Endocrinol Metab Clin N Am"},{"key":"10.1016\/j.wneu.2024.08.027_bib4","doi-asserted-by":"crossref","first-page":"9919","DOI":"10.1038\/s41598-022-12980-1","article-title":"Prospective intraoperative and histologic evaluation of cavernous sinus medial wall invasion by pituitary adenomas and its implications for acromegaly remission outcomes","volume":"12","author":"Mohyeldin","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.wneu.2024.08.027_bib5","first-page":"1006","article-title":"Pure endoscopic endonasal approach for pituitary adenomas: early surgical results in 200 patients and comparison with previous microsurgical series","volume":"62","author":"Dehdashti","year":"2008","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.08.027_bib6","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1097\/SCS.0000000000007293","article-title":"Correlation between anatomic variations of sphenoid sinuses and pituitary adenoma","volume":"32","author":"Guo","year":"2021","journal-title":"J\u00a0Craniofac Surg"},{"key":"10.1016\/j.wneu.2024.08.027_bib7","article-title":"Invasive corridor of clivus extension in pituitary adenoma: bony anatomic consideration, surgical outcome and technical nuances","volume":"11","author":"Wu","year":"2021","journal-title":"Front Oncol"},{"key":"10.1016\/j.wneu.2024.08.027_bib8","first-page":"1706","article-title":"Silent corticotroph pituitary adenomas: clinical characteristics, long-term outcomes, and management of disease recurrence","volume":"135","author":"Strickland","year":"2021","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2024.08.027_bib9","doi-asserted-by":"crossref","DOI":"10.3390\/cancers13236134","article-title":"An update on silent corticotroph adenomas: diagnosis, mechanisms, clinical features, and management","volume":"13","author":"Jiang","year":"2021","journal-title":"Cancers"},{"key":"10.1016\/j.wneu.2024.08.027_bib10","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s12022-022-09703-7","article-title":"Overview of the 2022 WHO classification of pituitary tumors","volume":"33","author":"Asa","year":"2022","journal-title":"Endocr Pathol"},{"key":"10.1016\/j.wneu.2024.08.027_bib11","first-page":"669","article-title":"Sphenoid sinus anatomy and suprasellar extension of pituitary tumors","volume":"119","author":"Ramakrishnan","year":"2013","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2024.08.027_bib12","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1227\/01.neu.0000429858.96652.1e","article-title":"A\u00a0comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas","volume":"73","author":"Jahangiri","year":"2013","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.08.027_bib13","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1080\/02688690500081230","article-title":"A\u00a0spectrum of behaviour in silent corticotroph pituitary adenomas","volume":"19","author":"Baldeweg","year":"2005","journal-title":"Br J Neurosurg"},{"key":"10.1016\/j.wneu.2024.08.027_bib14","first-page":"723","article-title":"Clinically silent corticotroph tumors of the pituitary gland","volume":"47","author":"Scheithauer","year":"2000","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.08.027_bib15","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1227\/01.NEU.0000223437.51435.6E","article-title":"Pathobiology of pituitary adenomas and carcinomas","volume":"59","author":"Scheithauer","year":"2006","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.08.027_bib16","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1227\/01.NEU.0000290906.53685.79","article-title":"A\u00a0study of the correlation between morphological findings and biological activities in clinically nonfunctioning pituitary adenomas","volume":"61","author":"Yamada","year":"2007","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.08.027_bib17","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1007\/s11102-022-01217-z","article-title":"Growth hormone secreting pituitary adenomas show distinct extrasellar extension patterns compared to nonfunctional pituitary adenomas","volume":"25","author":"Pangal","year":"2022","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2024.08.027_bib18","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1007\/s12020-023-03449-w","article-title":"The clinicopathological features and prognosis of silent corticotroph tumors: an updated systematic review and meta-analysis","volume":"82","author":"Vuong","year":"2023","journal-title":"Endocrine"},{"key":"10.1016\/j.wneu.2024.08.027_bib19","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s00401-017-1769-8","article-title":"The 2017 World Health Organization classification of tumors of the pituitary gland: a summary","volume":"134","author":"Lopes","year":"2017","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.wneu.2024.08.027_bib20","first-page":"1039","article-title":"Recurrence in silent corticotroph adenomas after primary treatment: a systematic review and meta-analysis","volume":"104","author":"Fountas","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2024.08.027_bib21","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1046\/j.1365-2265.2003.01674.x","article-title":"Non-functioning pituitary adenomas with positive immunoreactivity for ACTH behave more aggressively than ACTH immunonegative tumours but do not recur more frequently","volume":"58","author":"Bradley","year":"2003","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.wneu.2024.08.027_bib22","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1007\/s12020-017-1447-6","article-title":"Clinical profile of silent growth hormone pituitary adenomas; higher recurrence rate compared to silent gonadotroph pituitary tumors, a large single center experience","volume":"58","author":"Langlois","year":"2017","journal-title":"Endocrine"},{"key":"10.1016\/j.wneu.2024.08.027_bib23","doi-asserted-by":"crossref","first-page":"132","DOI":"10.7150\/thno.47525","article-title":"Transcriptomic analysis identifies a tumor subtype mRNA classifier for invasive non-functioning pituitary neuroendocrine tumor diagnostics","volume":"11","author":"Bao","year":"2021","journal-title":"Theranostics"},{"key":"10.1016\/j.wneu.2024.08.027_bib24","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/s10014-023-00462-9","article-title":"Immunohistochemical and ultrastructural review of six cases previously diagnosed as null cell PitNETs","volume":"40","author":"Inoshita","year":"2023","journal-title":"Brain Tumor Pathol"},{"key":"10.1016\/j.wneu.2024.08.027_bib25","doi-asserted-by":"crossref","DOI":"10.1111\/nan.12870","article-title":"Unveiling the identities of null cell tumours: epigenomics corroborate subtle histological cues in pituitary neuroendocrine tumour\/adenoma classification","volume":"49","author":"Dottermusch","year":"2023","journal-title":"Neuropathol Appl Neurobiol"},{"key":"10.1016\/j.wneu.2024.08.027_bib26","first-page":"1173","article-title":"Clinicopathological correlates of extrasellar growth patterns in pituitary adenomas","volume":"22","author":"Sarkar","year":"2015","journal-title":"J\u00a0Clin Neurosci Off J Neurosurg Soc Australas"},{"key":"10.1016\/j.wneu.2024.08.027_bib27","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ccell.2019.11.002","article-title":"Pangenomic classification of pituitary neuroendocrine tumors","volume":"37","author":"Neou","year":"2020","journal-title":"Cancer Cell"},{"key":"10.1016\/j.wneu.2024.08.027_bib28","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1111\/j.1365-2265.2009.03673.x","article-title":"Silent corticotroph adenomas have unique recurrence characteristics compared with other nonfunctioning pituitary adenomas","volume":"72","author":"Cho","year":"2010","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.wneu.2024.08.027_bib29","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/s11102-023-01298-4","article-title":"Refractory nonfunctioning pituitary adenomas","volume":"26","author":"Kolitz","year":"2023","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2024.08.027_bib30","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1046\/j.1440-1789.2001.00409.x","article-title":"A\u00a0case of non-functioning pituitary adenoma with Cushing\u2019s syndrome upon recurrence","volume":"21","author":"Yokoyama","year":"2001","journal-title":"Neuropathology"},{"key":"10.1016\/j.wneu.2024.08.027_bib31","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1001\/archinte.1983.00350050206041","article-title":"Cushing\u2019s disease in a patient with a \u201cnonfunctioning\u201d pituitary tumor. Spontaneous development and remission","volume":"143","author":"Gogel","year":"1983","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.wneu.2024.08.027_bib32","first-page":"272","article-title":"Response of silent corticotroph pituitary carcinoma to chemotherapy: case report","volume":"60","author":"He","year":"2016","journal-title":"J\u00a0Neurosurg Sci"},{"key":"10.1016\/j.wneu.2024.08.027_bib33","doi-asserted-by":"crossref","first-page":"162","DOI":"10.14310\/horm.2002.1307","article-title":"Aggressive silent corticotroph adenoma progressing to pituitary carcinoma: the role of temozolomide therapy","volume":"10","author":"Moshkin","year":"2011","journal-title":"Horm Athens Greece"},{"key":"10.1016\/j.wneu.2024.08.027_bib34","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/s11102-018-0872-8","article-title":"Corticotrophic pituitary carcinoma with cervical metastases: case series and literature review","volume":"21","author":"Yoo","year":"2018","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2024.08.027_bib35","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1055\/s-0039-1683435","article-title":"A\u00a0population-level analysis of pituitary carcinoma from the national cancer database","volume":"81","author":"Carey","year":"2020","journal-title":"J\u00a0Neurol Surg Part B Skull Base"},{"key":"10.1016\/j.wneu.2024.08.027_bib36","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s11102-018-0864-8","article-title":"Silent corticotroph adenomas","volume":"21","author":"Ben-Shlomo","year":"2018","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2024.08.027_bib37","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1227\/01.NEU.0000088660.16904.F7","article-title":"Clinical characteristics of silent corticotrophic adenomas and creation of an internet-accessible database to facilitate their multi-institutional study","volume":"53","author":"Webb","year":"2003","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.08.027_bib38","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1507\/endocrj.49.285","article-title":"Comparison of ACTH secretion in Cushing\u2019s adenoma and clinically silent corticotroph adenoma by cell immunoblot assay","volume":"49","author":"Kojima","year":"2002","journal-title":"Endocr J"},{"key":"10.1016\/j.wneu.2024.08.027_bib39","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1007\/s12672-010-0014-x","article-title":"Silent corticogonadotroph adenomas: clinical and cellular characteristics and long-term outcomes","volume":"1","author":"Cooper","year":"2010","journal-title":"Horm Cancer"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875024013858?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875024013858?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T01:31:14Z","timestamp":1749691874000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875024013858"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":39,"alternative-id":["S1878875024013858"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2024.08.027","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Silent Corticotroph Adenomas Demonstrate Predilection for Sphenoid Sinus, Cavernous Sinus, and Clival Invasion Compared with Other Subtypes","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2024.08.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}