{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T18:28:30Z","timestamp":1793384910553,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["313047\/2023\\u2013-5"],"award-info":[{"award-number":["313047\/2023\\u2013-5"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.wneu.2024.08.149","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T15:24:50Z","timestamp":1725377090000},"page":"e411-e422","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Trends in Hospitalization and Mortality Rates Associated with Subarachnoid Hemorrhage and Unruptured Cerebral Aneurysms in Brazil"],"prefix":"10.1016","volume":"191","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9754-6648","authenticated-orcid":false,"given":"Gianfelipe Belini","family":"Poliseli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1678-5262","authenticated-orcid":false,"given":"Thiago Ara\u00fajo dos","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9lio Rubens de Carvalho","family":"Nunes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassiano","family":"Vict\u00f3ria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5712-9783","authenticated-orcid":false,"given":"Marco Ant\u00f4nio","family":"Zanini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6436-9307","authenticated-orcid":false,"given":"Pedro Tadao","family":"Hamamoto Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2024.08.149_bib1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1227\/01.neu.0000430290.93304.33","article-title":"The epidemiology of admissions of nontraumatic subarachnoid hemorrhage in the United States","volume":"73","author":"Rincon","year":"2013","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.08.149_bib2","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1111\/j.1468-1331.2008.02280.x","article-title":"Diagnosing headache in the emergency department: what is more important? Being right, or not being wrong?","volume":"15","author":"Edlow","year":"2008","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.wneu.2024.08.149_bib3","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1056\/NEJMcp1605827","article-title":"Subarachnoid hemorrhage","volume":"377","author":"Lawton","year":"2017","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.wneu.2024.08.149_bib4","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S1474-4422(14)70015-8","article-title":"Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening","volume":"13","author":"Brown","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.wneu.2024.08.149_bib5","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S1474-4422(09)70126-7","article-title":"Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis","volume":"8","author":"Nieuwkamp","year":"2009","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.wneu.2024.08.149_bib6","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1212\/WNL.50.5.1413","article-title":"The burden, trends, and demographics of mortality from subarachnoid hemorrhage","volume":"505","author":"Johnston","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2024.08.149_bib7","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s12028-019-00905-2","article-title":"Outcome, return to work and health-related costs after aneurysmal subarachnoid hemorrhage","volume":"33","author":"Seule","year":"2020","journal-title":"Neurocrit Care"},{"key":"10.1016\/j.wneu.2024.08.149_bib8","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1136\/neurintsurg-2019-015418","article-title":"Treatment and diagnosis of cerebral aneurysms in the post-International Subarachnoid Aneurysm Trial (ISAT) era: trends and outcomes","volume":"12","author":"Luther","year":"2020","journal-title":"J\u00a0Neurointerv Surg"},{"key":"10.1016\/j.wneu.2024.08.149_bib9","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1056\/NEJMoa1113260","article-title":"The natural course of unruptured cerebral aneurysms in a Japanese cohort","volume":"366","author":"Morita","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.wneu.2024.08.149_bib10","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1093\/neuros\/nyx226","article-title":"Aneurysm morphology and prediction of rupture: an international study of unruptured intracranial aneurysms analysis","volume":"824","author":"Mocco","year":"2018","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.08.149_bib11","first-page":"1062","article-title":"How definitive treatment affects the rupture rate of unruptured cerebral aneurysms: a competing risk survival analysis","volume":"132","author":"Kimura","year":"2019","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2024.08.149_bib12","article-title":"Trends of ruptured and unruptured aneurysms treatment in the United States in post-ISAT era: a national inpatient sample analysis","volume":"10","author":"Salem","year":"2021","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.wneu.2024.08.149_bib13","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1212\/WNL.0000000000003091","article-title":"Incidence of subarachnoid hemorrhage is decreasing together with decreasing smoking rates","volume":"87","author":"Korja","year":"2016","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2024.08.149_bib14","doi-asserted-by":"crossref","first-page":"e123","DOI":"10.1212\/WNL.0000000000201340","article-title":"Trends in the incidence of spontaneous subarachnoid hemorrhages in the United States, 2007-2017","volume":"100","author":"Xia","year":"2023","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2024.08.149_bib15","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1161\/STROKEAHA.120.029538","article-title":"Incidence and outcome of aneurysmal subarachnoid hemorrhage: the Swiss Study on Subarachnoid Hemorrhage (Swiss SOS)","volume":"52","author":"Bervini","year":"2021","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2024.08.149_bib16","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1177\/23969873231198324","article-title":"Epidemiology and treatment of atraumatic subarachnoid hemorrhage over 10 years in a population-based registry","volume":"9","author":"Ragaglini","year":"2024","journal-title":"Eur Stroke J"},{"key":"10.1016\/j.wneu.2024.08.149_bib17","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1007\/s00701-020-04463-x","article-title":"Incidence and case fatality of aneurysmal subarachnoid hemorrhage admitted to hospital between 2008 and 2014 in Norway","volume":"162","author":"\u00d8ie","year":"2020","journal-title":"Acta Neurochir"},{"key":"10.1016\/j.wneu.2024.08.149_bib18","doi-asserted-by":"crossref","first-page":"e438","DOI":"10.1016\/j.wneu.2020.08.186","article-title":"Incidence and case-fatality of aneurysmal subarachnoid hemorrhage in Australia, 2008-2018","volume":"144","author":"Huang","year":"2020","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2024.08.149_bib19","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1161\/STROKEAHA.116.013637","article-title":"First-ever stroke and transient ischemic attack incidence and 30-day case-fatality rates in a population-based study in Argentina","volume":"47","author":"Bahit","year":"2016","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2024.08.149_bib20","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1177\/23969873231202392","article-title":"Trends in hemorrhagic stroke incidence and mortality in a National Stroke Registry of a multi-ethnic Asian population","volume":"9","author":"Lim","year":"2024","journal-title":"Eur Stroke J"},{"key":"10.1016\/j.wneu.2024.08.149_bib21","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1001\/jamaneurol.2019.0006","article-title":"Worldwide incidence of aneurysmal subarachnoid hemorrhage according to region, time period, blood pressure, and smoking prevalence in the population: a systematic review and meta-analysis","volume":"76","author":"Etminan","year":"2019","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.wneu.2024.08.149_bib22","first-page":"1039","article-title":"National socioeconomic indicators are associated with outcomes after aneurysmal subarachnoid hemorrhage: a hierarchical mixed-effects analysis","volume":"1215","author":"Guha","year":"2014","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2024.08.149_bib23","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1227\/NEU.0000000000000850","article-title":"High subarachnoid hemorrhage patient volume associated with lower mortality and better outcomes","volume":"773","author":"Pandey","year":"2015","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.08.149_bib24","doi-asserted-by":"crossref","DOI":"10.1093\/intqhc\/mzab019","article-title":"Time and predictors of time to treatment for aneurysmal subarachnoid haemorrhage (aSAH): a systematic review","volume":"33","author":"Phuong Nguyen","year":"2021","journal-title":"Int J Qual Health Care"},{"key":"10.1016\/j.wneu.2024.08.149_bib25","first-page":"2529","article-title":"Health insurance coverage in Brazil: analyzing data from the National Health Survey, 2013 and 2019","volume":"26","author":"Souza","year":"2021","journal-title":"Cien Saude Colet"},{"key":"10.1016\/j.wneu.2024.08.149_bib26","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1136\/jnnp.2009.172098","article-title":"Incidence of stroke subtypes, prognosis and prevalence of risk factors in Joinville, Brazil: a 2 year community based study","volume":"80","author":"Cabral","year":"2009","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.wneu.2024.08.149_bib27","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1159\/000445060","article-title":"Trends of stroke incidence from 1995 to 2013 in Joinville, Brazil","volume":"46","author":"Cabral","year":"2016","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.wneu.2024.08.149_bib28","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1016\/S0140-6736(11)60054-8","article-title":"The Brazilian health system: history, advances, and challenges","volume":"377","author":"Paim","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.wneu.2024.08.149_bib29","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0140-6736(19)31243-7","article-title":"Brazil's unified health system: the first 30 years and prospects for the future","volume":"394","author":"Castro","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.wneu.2024.08.149_bib30","doi-asserted-by":"crossref","first-page":"e492","DOI":"10.1016\/S2542-5196(19)30244-X","article-title":"Health inequalities in Latin America: persistent gaps in life expectancy","volume":"3","author":"D\u00e1vila-Cervantes","year":"2019","journal-title":"Lancet Planet Health"},{"key":"10.1016\/j.wneu.2024.08.149_bib31","article-title":"Time trend in the prevalence of systemic arterial hypertension in Brazil","volume":"33","author":"Lobo","year":"2017","journal-title":"Cad Sa\u00fade P\u00fablica"},{"key":"10.1016\/j.wneu.2024.08.149_bib32","doi-asserted-by":"crossref","first-page":"4007","DOI":"10.1590\/1413-81232021269.08092021","article-title":"Trends in the prevalence of systemic arterial hypertension and health care service use in Brazil over a decade (2008-2019)","volume":"26","author":"Juli\u00e3o","year":"2021","journal-title":"Cien Saude Colet"},{"key":"10.1016\/j.wneu.2024.08.149_bib33","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12963-020-00215-2","article-title":"Trends in prevalence and mortality burden attributable to smoking, Brazil and federated units, 1990 and 2017","volume":"18","author":"Malta","year":"2020","journal-title":"Popul Health Metr"},{"key":"10.1016\/j.wneu.2024.08.149_bib35","doi-asserted-by":"crossref","first-page":"E13","DOI":"10.3171\/2020.8.FOCUS20571","article-title":"Malpractice and socioeconomic aspects in neurosurgery: a developing-country reality","volume":"49","author":"de Mac\u00eado Filho","year":"2020","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2024.08.149_bib36","article-title":"Social determinants of health and survival on Brazilian patients with glioblastoma: a retrospective analysis of a large populational database","volume":"4","author":"Marta","year":"2021","journal-title":"Lancet Reg Health Am"},{"key":"10.1016\/j.wneu.2024.08.149_bib37","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1212\/WNL.0b013e3181dd42b3","article-title":"Time trends in outcome of subarachnoid hemorrhage: population-based study and systematic review","volume":"74","author":"Lovelock","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2024.08.149_bib38","first-page":"698","article-title":"The falling rates of hospital admission, case fatality, and population-based mortality for subarachnoid hemorrhage in England, 1999-2010","volume":"1253","author":"Mukhtar","year":"2016","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2024.08.149_bib39","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1159\/000526983","article-title":"Case fatality rates of subarachnoid hemorrhage are decreasing with substantial between-country variation: a systematic review of population-based studies between 1980 and 2020","volume":"56","author":"Mahlam\u00e4ki","year":"2022","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.wneu.2024.08.149_bib40","doi-asserted-by":"crossref","first-page":"e309","DOI":"10.1016\/j.wneu.2023.09.066","article-title":"Current state of Brazilian neurosurgery: evaluation of burden of care and case volume","volume":"180","author":"Koester","year":"2023","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2024.08.149_bib41","doi-asserted-by":"crossref","first-page":"e250","DOI":"10.1016\/j.wneu.2023.12.068","article-title":"Impact of medical and neurologic complications on the outcome of patients with aneurysmal subarachnoid hemorrhage in a middle-income country","volume":"183","author":"Vasconcellos de Oliveira Souza","year":"2024","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2024.08.149_bib42","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1056\/NEJMoa070972","article-title":"Incidental findings on brain MRI in the general population","volume":"357","author":"Vernooij","year":"2007","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.wneu.2024.08.149_bib43","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/S1474-4422(11)70109-0","article-title":"Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis","volume":"10","author":"Vlak","year":"2011","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.wneu.2024.08.149_bib44","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S1474-4422(13)70263-1","article-title":"Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies","volume":"13","author":"Greving","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.wneu.2024.08.149_bib45","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1038\/nrneurol.2016.150","article-title":"Unruptured intracranial aneurysms: development, rupture and preventive management","volume":"12","author":"Etminan","year":"2016","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.wneu.2024.08.149_bib46","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1161\/STROKEAHA.118.021030","article-title":"Unruptured intracranial aneurysms","volume":"499","author":"Hackenberg","year":"2018","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2024.08.149_bib47","doi-asserted-by":"crossref","first-page":"e415","DOI":"10.1016\/j.wneu.2023.09.081","article-title":"Mortality after microsurgical treatment of unruptured intracranial aneurysms in the modern era","volume":"180","author":"Catapano","year":"2023","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2024.08.149_bib48","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1159\/000506396","article-title":"Regional and country-specific burden of ischaemic stroke, intracerebral haemorrhage and subarachnoid haemorrhage: a systematic analysis of the global burden of disease study 2017","volume":"54","author":"Krishnamurthi","year":"2020","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.wneu.2024.08.149_bib49","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s12028-022-01476-5","article-title":"Trends in admissions and outcomes for treatment of aneurysmal subarachnoid hemorrhage in the United States","volume":"37","author":"Wahood","year":"2022","journal-title":"Neurocrit Care"},{"key":"10.1016\/j.wneu.2024.08.149_bib50","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/ene.14517","article-title":"Aguinaga-ontoso I. trends in mortality from stroke in the European union, 1996-2015","volume":"28","author":"Soto","year":"2021","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.wneu.2024.08.149_bib51","first-page":"297","article-title":"Detection rates and trends of asymptomatic unruptured intracranial aneurysms from 2005 to 2019","volume":"94","author":"Laukka","year":"2024","journal-title":"Neurosurgery"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875024015183?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875024015183?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T01:35:08Z","timestamp":1749692108000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875024015183"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":50,"alternative-id":["S1878875024015183"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2024.08.149","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Trends in Hospitalization and Mortality Rates Associated with Subarachnoid Hemorrhage and Unruptured Cerebral Aneurysms in Brazil","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2024.08.149","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}