{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T21:47:11Z","timestamp":1783460831935,"version":"3.55.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T00:00:00Z","timestamp":1730937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.wneu.2024.10.097","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T18:52:13Z","timestamp":1732128733000},"page":"123368","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["The Correlation of Vessel Wall Macrophage Infiltration With Hemosiderin in Arteriovenous Malformations"],"prefix":"10.1016","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0147-3139","authenticated-orcid":false,"given":"Jessica","family":"Hossa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8063-9389","authenticated-orcid":false,"given":"Laura Stone","family":"McGuire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tibor","family":"Valyi-Nagy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana","family":"Abou-Mrad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Theiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mpuekela","family":"Tshibangu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3601-9534","authenticated-orcid":false,"given":"Adrusht","family":"Madapoosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fady T.","family":"Charbel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1491-4634","authenticated-orcid":false,"given":"Ali","family":"Alaraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2024.10.097_bib1","doi-asserted-by":"crossref","first-page":"4841","DOI":"10.1002\/jcp.30226","article-title":"Neurovascular inflammation in the pathogenesis of brain arteriovenous malformations","volume":"236","author":"Krithika","year":"2021","journal-title":"J\u00a0Cell Physiol"},{"key":"10.1016\/j.wneu.2024.10.097_bib2","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1227\/01.neu.0000333306.64683.b5","article-title":"Evidence of inflammatory cell involvement in brain arteriovenous malformations","volume":"62","author":"Chen","year":"2008","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.10.097_bib3","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/jcbfm.2014.179","article-title":"Biology of cerebral arteriovenous malformations with a focus on inflammation","volume":"35","author":"Mouchtouris","year":"2015","journal-title":"J\u00a0Cerebr Blood Flow Metabol"},{"key":"10.1016\/j.wneu.2024.10.097_bib4","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1227\/01.NEU.0000334417.56742.24","article-title":"Aberrant angiogenic characteristics of human brain arteriovenous malformation endothelial cells","volume":"64","author":"Jabbour","year":"2009","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.10.097_bib5","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.wneu.2021.07.106","article-title":"Current concepts and perspectives on brain arteriovenous malformations: a review of pathogenesis and multidisciplinary treatment","volume":"159","author":"Sugiyama","year":"2022","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2024.10.097_bib6","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.3892\/mmr.2013.1332","article-title":"Relevance of IL-6 and MMP-9 to cerebral arteriovenous malformation and hemorrhage","volume":"7","author":"Li","year":"2013","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.wneu.2024.10.097_bib7","doi-asserted-by":"crossref","first-page":"E21","DOI":"10.3171\/2019.5.FOCUS19234","article-title":"Flow-induced, inflammation-mediated arterial wall remodeling in the formation and progression of intracranial aneurysms","volume":"47","author":"Fr\u00f6sen","year":"2019","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2024.10.097_bib8","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.630381","article-title":"Vascular macrophages as therapeutic targets to treat intracranial aneurysms","volume":"12","author":"Muhammad","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.wneu.2024.10.097_bib9","doi-asserted-by":"crossref","first-page":"403","DOI":"10.5114\/fn.2022.122342","article-title":"Impact of inflammation-related degenerative changes on the wall strength of unruptured intracranial aneurysms: a pilot study","volume":"60","author":"Lombarski","year":"2022","journal-title":"Folia Neuropathol"},{"key":"10.1016\/j.wneu.2024.10.097_bib10","first-page":"902","article-title":"Decreased contrast enhancement on high-resolution vessel wall imaging of unruptured intracranial aneurysms in patients taking aspirin","volume":"134","author":"Roa","year":"2020","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2024.10.097_bib11","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1161\/STROKEAHA.108.532556","article-title":"Impact of monocyte chemoattractant protein-1 deficiency on cerebral aneurysm formation","volume":"40","author":"Aoki","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2024.10.097_bib12","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1177\/15910199221143189","article-title":"Vessel wall imaging and quantitative flow assessment in arteriovenous malformations: a feasibility study","volume":"30","author":"McGuire","year":"2024","journal-title":"Intervent Neuroradiol"},{"key":"10.1016\/j.wneu.2024.10.097_bib13","first-page":"333","article-title":"Are hemodynamics responsible for inflammatory changes in venous vessel walls? A quantitative study of wall-enhancing intracranial arteriovenous malformation draining veins","volume":"141","author":"Stahl","year":"2024","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2024.10.097_bib14","article-title":"The REDCap consortium: building an international community of software platform partners","volume":"95","author":"Harris","year":"2019","journal-title":"J\u00a0Biomed Inf"},{"key":"10.1016\/j.wneu.2024.10.097_bib15","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J\u00a0Biomed Inf"},{"key":"10.1016\/j.wneu.2024.10.097_bib16","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.1161\/STROKEAHA.117.017785","article-title":"Higher flow is present in unruptured arteriovenous malformations with silent intralesional microhemorrhages","volume":"48","author":"Chen","year":"2017","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2024.10.097_bib17","doi-asserted-by":"crossref","first-page":"114","DOI":"10.5414\/NP300937","article-title":"Morphometric characterization of brain arteriovenous malformations for clinical and radiological studies to identify silent intralesional microhemorrhages","volume":"35","author":"Pekmezci","year":"2016","journal-title":"Clin Neuropathol"},{"key":"10.1016\/j.wneu.2024.10.097_bib18","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1161\/STROKEAHA.111.647263","article-title":"Silent intralesional microhemorrhage as a risk factor for brain arteriovenous malformation rupture","volume":"43","author":"Guo","year":"2023","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2024.10.097_bib19","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1161\/STROKEAHA.114.008569","article-title":"Quantitative assessment of changes in cerebral arteriovenous malformation hemodynamics after embolization","volume":"46","author":"Alaraj","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2024.10.097_bib20","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1093\/neuros\/nyx351","article-title":"Contrast time-density time on digital subtraction angiography correlates with cerebral arteriovenous malformation flow measured by quantitative magnetic resonance angiography, angioarchitecture, and hemorrhage","volume":"83","author":"Brunozzi","year":"2018","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2024.10.097_bib21","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jocn.2016.02.034","article-title":"Relationship of pulsatility and resistance indices to cerebral arteriovenous malformation angioarchitectural features and hemorrhage","volume":"33","author":"Shakur","year":"2016","journal-title":"J\u00a0Clin Neurosci"},{"key":"10.1016\/j.wneu.2024.10.097_bib22","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1161\/STROKEAHA.116.015666","article-title":"Cerebral arteriovenous malformation flow is associated with venous intimal hyperplasia","volume":"48","author":"Shakur","year":"2017","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2024.10.097_bib23","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.wneu.2023.08.047","article-title":"Rupture-risk stratifying patients with cerebral arteriovenous malformations using quantitative hemodynamic flow measurements","volume":"179","author":"Nico","year":"2023","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2024.10.097_bib24","first-page":"138","article-title":"The correlation of cerebral arteriovenous malformation flow measured by quantitative MR angiography on MR-detected arteriovenous malformation microhemorrhage","volume":"141","author":"Hossa","year":"2024","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.wneu.2024.10.097_bib25","doi-asserted-by":"crossref","first-page":"3427","DOI":"10.1161\/STROKEAHA.114.006622","article-title":"Effects of extracranial carotid stenosis on intracranial blood flow","volume":"45","author":"Shakur","year":"2014","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2024.10.097_bib26","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1161\/STROKEAHA.110.594739","article-title":"Detection of intracranial in-stent restenosis using quantitative magnetic resonance angiography","volume":"41","author":"Amin-Hanjani","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.wneu.2024.10.097_bib27","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.3174\/ajnr.A2546","article-title":"In\u00a0vivo evaluation of quantitative MR angiography in a canine carotid artery stenosis model","volume":"32","author":"Calderon-Arnulphi","year":"2011","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.wneu.2024.10.097_bib28","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.3174\/ajnr.A0582","article-title":"Regional cerebral blood flow using quantitative MR angiography","volume":"28","author":"Zhao","year":"2007","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.wneu.2024.10.097_bib29","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S0730-725X(00)00157-0","article-title":"Improved phase-contrast flow quantification by three-dimensional vessel localization","volume":"18","author":"Zhao","year":"2000","journal-title":"Magn Reson Imaging"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875024018011?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875024018011?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T05:59:38Z","timestamp":1750226378000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875024018011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":29,"alternative-id":["S1878875024018011"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2024.10.097","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Correlation of Vessel Wall Macrophage Infiltration With Hemosiderin in Arteriovenous Malformations","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2024.10.097","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"123368"}}