{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T14:10:04Z","timestamp":1781619004197,"version":"3.54.5"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:00:00Z","timestamp":1764028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100015285","name":"Hebei Province Medical Science Research Key Project","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015285","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.wneu.2025.124685","type":"journal-article","created":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T00:27:30Z","timestamp":1764635250000},"page":"124685","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Percutaneous Balloon Compression Exerts Multidimensional Efficacy in Trigeminal Neuralgia via Neuroinflammation and Neurotransmitter Regulation"],"prefix":"10.1016","volume":"205","author":[{"given":"Yihui","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haowei","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zenghui","family":"Xi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinzhan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenchang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2025.124685_bib1","article-title":"Trigeminal neuralgia in advanced head and neck cancer: a complex palliative care case","volume":"15","author":"Vidal","year":"2023","journal-title":"Cureus"},{"key":"10.1016\/j.wneu.2025.124685_bib2","doi-asserted-by":"crossref","first-page":"109","DOI":"10.2174\/1570159X17666191010094350","article-title":"Trigeminal neuralgia: basic and clinical aspects","volume":"18","author":"Araya","year":"2020","journal-title":"CN"},{"key":"10.1016\/j.wneu.2025.124685_bib3","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/01.NURSE.0000525995.89850.10","article-title":"What\u2019s trigeminal neuralgia?","volume":"47","author":"Bitanga","year":"2017","journal-title":"Nursing"},{"key":"10.1016\/j.wneu.2025.124685_bib4","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/S1474-4422(20)30233-7","article-title":"Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia","volume":"19","author":"Bendtsen","year":"2020","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.wneu.2025.124685_bib5","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1093\/brain\/124.12.2347","article-title":"Trigeminal neuralgia: pathology and pathogenesis","volume":"124","author":"Love","year":"2001","journal-title":"Brain"},{"key":"10.1016\/j.wneu.2025.124685_bib6","doi-asserted-by":"crossref","DOI":"10.4065\/mcp.2011.0420","article-title":"Impressive vascular compression of the trigeminal nerve","volume":"86","author":"Demetriades","year":"2011","journal-title":"Mayo Clinic Proc"},{"key":"10.1016\/j.wneu.2025.124685_bib7","article-title":"Exploring the role of inflammatory biomarkers in trigeminal neuralgia","volume":"43","author":"Lai","year":"2025","journal-title":"Brain Behav Immun Health"},{"key":"10.1016\/j.wneu.2025.124685_bib8","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1111\/j.1745-7254.2008.00801.x","article-title":"Glial involvement in trigeminal central sensitization","volume":"29","author":"Feng","year":"2008","journal-title":"Acta Pharmacologica Sinica"},{"key":"10.1016\/j.wneu.2025.124685_bib9","article-title":"OTULIN\u2019s influence on neuroinflammation and pain modulation in trigeminal neuralgia","volume":"30","author":"Wang","year":"2024","journal-title":"CNS Neurosci Ther"},{"key":"10.1016\/j.wneu.2025.124685_bib10","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1007\/s40265-018-0964-9","article-title":"Current and innovative pharmacological options to treat typical and atypical trigeminal neuralgia","volume":"78","author":"Di Stefano","year":"2018","journal-title":"Drugs"},{"key":"10.1016\/j.wneu.2025.124685_bib11","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1212\/CON.0000000000000451","article-title":"Trigeminal neuralgia","volume":"23","author":"Cruccu","year":"2017","journal-title":"Continuum"},{"key":"10.1016\/j.wneu.2025.124685_bib12","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1129-2377-15-34","article-title":"Natural history and outcome of 200 outpatients with classical trigeminal neuralgia treated with carbamazepine or oxcarbazepine in a tertiary centre for neuropathic pain","volume":"15","author":"Di","year":"2014","journal-title":"J Headache Pain"},{"key":"10.1016\/j.wneu.2025.124685_bib13","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1186\/s10194-015-0563-z","article-title":"Comparison of tolerability and adverse symptoms in oxcarbazepine and carbamazepine in the treatment of trigeminal neuralgia and neuralgiform headaches using the Liverpool adverse events profile (AEP)","volume":"16","author":"Besi","year":"2015","journal-title":"J Headache Pain"},{"key":"10.1016\/j.wneu.2025.124685_bib14","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1080\/02688697.2018.1504882","article-title":"Percutaneous retrogasserian glycerol rhizotomy for trigeminal neuralgia: an alternative technique","volume":"32","author":"Paranathala","year":"2018","journal-title":"Br J Neurosurg"},{"key":"10.1016\/j.wneu.2025.124685_bib15","doi-asserted-by":"crossref","DOI":"10.3171\/CASE23173","article-title":"Pterygoid venous plexus anastomosis in trigeminal percutaneous glycerol rhizotomy: illustrative case","volume":"6","author":"Cordeiro","year":"2023","journal-title":"J Neurosurg Case Lessons"},{"key":"10.1016\/j.wneu.2025.124685_bib16","article-title":"Percutaneous radiofrequency trigeminal rhizotomy benefits in patients with refractory trigeminal neuralgia","volume":"101","author":"Yang","year":"2022","journal-title":"Medicine"},{"key":"10.1016\/j.wneu.2025.124685_bib17","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.neurol.2021.07.019","article-title":"An unknown complication of percutaneous radiofrequency rhizotomy in trigeminal neuralgia","volume":"178","author":"Grini-Mazouzi","year":"2022","journal-title":"Revue Neurologique"},{"key":"10.1016\/j.wneu.2025.124685_bib18","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1080\/02688697.2020.1787341","article-title":"Efficacy of and risk factors for percutaneous balloon compression for trigeminal neuralgia in elderly patients","volume":"35","author":"Li","year":"2020","journal-title":"Br J Neurosurg"},{"key":"10.1016\/j.wneu.2025.124685_bib19","doi-asserted-by":"crossref","first-page":"e685","DOI":"10.1097\/SCS.0000000000006544","article-title":"Outcomes of treatment for elderly patients with trigeminal neuralgia: percutaneous balloon compression versus microvascular decompression","volume":"31","author":"Ni","year":"2020","journal-title":"J Craniofac Surg"},{"key":"10.1016\/j.wneu.2025.124685_bib20","article-title":"Clinical analysis of the treatment of primary trigeminal neuralgia by percutaneous balloon compression","volume":"9","author":"Wang","year":"2022","journal-title":"Front Surg"},{"key":"10.1016\/j.wneu.2025.124685_bib21","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.wneu.2011.05.021","article-title":"Long-term Follow-up of patients treated with percutaneous balloon compression for trigeminal neuralgia in Taiwan","volume":"76","author":"Chen","year":"2011","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2025.124685_bib22","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1590\/0004-282x-anp-2020-0115","article-title":"Trigeminal neuralgia recurrence: a comparison of microvascular decompression and percutaneous balloon compression: a five years follow-up study","volume":"79","author":"Chaves","year":"2021","journal-title":"Arq Neuro Psiquiatr"},{"key":"10.1016\/j.wneu.2025.124685_bib23","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.3171\/2022.2.JNS212644","article-title":"Multivariate models to predict pain recurrence and sensitive complications after percutaneous balloon compression in trigeminal neuralgia","volume":"137","author":"Kourilsky","year":"2022","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2025.124685_bib24","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000005379","article-title":"Percutaneous trigeminal ganglion radiofrequency thermocoagulation alleviates anxiety and depression disorders in patients with classic trigeminal neuralgia","volume":"95","author":"Tang","year":"2016","journal-title":"Medicine"},{"key":"10.1016\/j.wneu.2025.124685_bib25","doi-asserted-by":"crossref","DOI":"10.1093\/geroni\/igz036","article-title":"Effect size guidelines, sample size calculations, and statistical power in gerontology","volume":"3","author":"Brydges","year":"2019","journal-title":"Innov Aging"},{"key":"10.1016\/j.wneu.2025.124685_bib26","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1037\/0033-2909.112.1.155","article-title":"A power primer","volume":"112","author":"Cohen","year":"1992","journal-title":"Psychol Bull"},{"key":"10.1016\/j.wneu.2025.124685_bib27","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.2044-8341.1959.tb00467.x","article-title":"The assessment of anxiety states by rating","volume":"32","author":"Hamilton","year":"1959","journal-title":"Br J Med Psychol"},{"key":"10.1016\/j.wneu.2025.124685_bib28","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.wneu.2025.124685_bib29","doi-asserted-by":"crossref","first-page":"7012","DOI":"10.3390\/ijerph17197012","article-title":"Chronic facial pain: trigeminal neuralgia, persistent idiopathic facial pain, and myofascial pain syndrome\u2014an evidence-based narrative review and etiological hypothesis","volume":"17","author":"Gerwin","year":"2020","journal-title":"IJERPH"},{"key":"10.1016\/j.wneu.2025.124685_bib30","doi-asserted-by":"crossref","DOI":"10.1177\/03000605221132027","article-title":"Quality of life after trigeminal nerve block in refractory trigeminal neuralgia: a retrospective cohort study and literature review","volume":"50","author":"Jacques","year":"2022","journal-title":"J Int Med Res"},{"key":"10.1016\/j.wneu.2025.124685_bib31","doi-asserted-by":"crossref","first-page":"814","DOI":"10.3340\/jkns.2020.0139","article-title":"Clinical outcome of percutaneous trigeminal nerve block in elderly patients in outpatient clinics","volume":"63","author":"Seo","year":"2020","journal-title":"J Korean Neurosurg Soc"},{"key":"10.1016\/j.wneu.2025.124685_bib32","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1097\/j.pain.0000000000000853","article-title":"Evaluating the impact of trigeminal neuralgia","volume":"158","author":"Zakrzewska","year":"2017","journal-title":"Pain"},{"key":"10.1016\/j.wneu.2025.124685_bib33","article-title":"Percutaneous balloon compression for the treatment of trigeminal neuralgia: a review of 10 years of clinical experience","volume":"15","author":"Valenzuela Cecchi","year":"2023","journal-title":"Cureus"},{"key":"10.1016\/j.wneu.2025.124685_bib34","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1007\/s13760-023-02310-1","article-title":"Percutaneous balloon compression for trigeminal neuralgia: experience and surgical techniques from a single institution","volume":"123","author":"Deng","year":"2023","journal-title":"Acta Neurol Belg"},{"issue":"Supplement","key":"10.1016\/j.wneu.2025.124685_bib35","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3171\/2010.8.GKS10879","article-title":"Quality-of-life outcomes after gamma knife surgery for trigeminal neuralgia","volume":"113","author":"Pan","year":"2010","journal-title":"JNS"},{"key":"10.1016\/j.wneu.2025.124685_bib36","doi-asserted-by":"crossref","first-page":"3905","DOI":"10.1007\/s00701-023-05823-z","article-title":"Effectiveness of percutaneous balloon compression (PBC) in improving physical function and quality of life in trigeminal neuralgia: a retrospective study","volume":"165","author":"Huang","year":"2023","journal-title":"Acta Neurochir"},{"key":"10.1016\/j.wneu.2025.124685_bib37","first-page":"E1255","article-title":"The analysis of percutaneous balloon compression on efficacy and negative emotion in the treatment of recurrent trigeminal neuralgia after surgical procedures","volume":"24","author":"Fan","year":"2021","journal-title":"Pain Physician"},{"key":"10.1016\/j.wneu.2025.124685_bib38","doi-asserted-by":"crossref","first-page":"530","DOI":"10.3390\/brainsci13040530","article-title":"Outcome comparison of drug-resistant trigeminal neuralgia surgical treatments\u2014an umbrella review of meta-analyses and systematic reviews","volume":"13","author":"Rapisarda","year":"2023","journal-title":"Brain Sci"},{"key":"10.1016\/j.wneu.2025.124685_bib39","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2022.953765","article-title":"Chinese expert consensus on minimally invasive interventional treatment of trigeminal neuralgia","volume":"15","author":"Fan","year":"2022","journal-title":"Front Mol Neurosci"},{"key":"10.1016\/j.wneu.2025.124685_bib40","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s00441-018-2922-y","article-title":"Substance P and pain chronicity","volume":"375","author":"Zieglg\u00e4nsberger","year":"2018","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.wneu.2025.124685_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/24740527.2019.1709163","article-title":"Biomarkers in temporomandibular disorder and trigeminal neuralgia: a conceptual framework for understanding chronic pain","volume":"4","author":"Doshi","year":"2020","journal-title":"Can J Pain"},{"key":"10.1016\/j.wneu.2025.124685_bib42","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1742-2094-7-27","article-title":"TNF-\u03b1 and neuropathic pain - a review","volume":"7","author":"Leung","year":"2010","journal-title":"J Neuroinflammation"},{"key":"10.1016\/j.wneu.2025.124685_bib43","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1590\/S0100-879X2003001000011","article-title":"Pentoxifylline decreases tumor necrosis factor and interleukin-1 during high tidal volume","volume":"36","author":"Oliveira-Junior","year":"2003","journal-title":"Braz J Med Biol Res"},{"key":"10.1016\/j.wneu.2025.124685_bib44","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1006\/clin.1997.4351","article-title":"The effects of general anesthesia on human peripheral immune cell distribution and cytokine production","volume":"83","author":"Brand","year":"1997","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1016\/j.wneu.2025.124685_bib45","article-title":"The role of neuron-specific enolase as a biomarker of response in percutaneous balloon compression for drug-resistant trigeminal neuralgia","author":"Burattini","year":"2025","journal-title":"Neurosurgery"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875025010435?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875025010435?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T13:14:36Z","timestamp":1781615676000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875025010435"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":45,"alternative-id":["S1878875025010435"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2025.124685","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Percutaneous Balloon Compression Exerts Multidimensional Efficacy in Trigeminal Neuralgia via Neuroinflammation and Neurotransmitter Regulation","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2025.124685","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"124685"}}